Negative / Null Result ReportMedicine
Gay A, Laudet F, Meynard P et al. · 2026 · Orthopaedics & traumatology, surgery & research : OTSR
Introduction Infection is a significant and challenging complication of total hip and knee arthroplasties. Diagnosing chronic periprosthetic joint infection (PJI) can be difficult, particularly when joint aspiration yields inconclusive…
View details →DOI: 10.1016/j.otsr.2025.104334 Negative / Null Result ReportOpen accessMedicine
Payton C, Kvaratskhelia N, Chalfin M et al. · 2025 · Journal of immigrant and minority health
Cancer screening can detect cancer at an early stage and decrease cancer morbidity and mortality. Refugee populations may have had limited access to cancer screening before arrival in the United States. A cross-sectional analysis of…
View details →DOI: 10.1007/s10903-025-01685-y Negative / Null Result ReportOpen accessMedicine
Kaseb A, Benider H, Treglia G et al. · 2025 · European journal of clinical investigation
Background 4D-CT has garnered attention as complementary imaging for patients with primary hyperparathyroidism (pHPT). Herein we evaluated a diagnostic strategy using [ 18 F]Fluorocholine Positron Emission Tomography/Computed Tomography…
View details →DOI: 10.1111/eci.14336 Negative / Null Result ReportOpen accessMedicine
Kuyucu M, Erdogan KM, Adiyaman D et al. · 2025 · Medicine
This study shares our 5-year experience with chorionic villus sampling (CVS) and analyzes the indications, results, and complications of this procedure. We conducted a retrospective analysis of data from singleton pregnancies that…
View details →DOI: 10.1097/md.0000000000041582 Negative / Null Result ReportOpen accessMedicine
Ramasindrazana B, Rahalison ZA, Gauthier P et al. · 2025 · PLoS neglected tropical diseases
Background The plague, caused by Yersinia pestis, remains a critical public health issue, particularly in endemic regions like Madagascar. Rapid and accurate detection of this pathogen is essential for effective outbreak management and…
View details →DOI: 10.1371/journal.pntd.0013278 Negative / Null Result ReportMedicine
Espada-Musitu D, Manero-Azua Á, Vado Y et al. · 2025 · Anales de pediatria
Advances in next-generation sequencing (NGS) technologies have made the detection of the molecular causes of paediatric diseases increasingly affordable, accessible and rapid. While exome sequencing and genome sequencing were until…
View details →DOI: 10.1016/j.anpede.2024.503712 Negative / Null Result ReportOpen accessMedicine
Paracino R, De Domenico P, Ricciuti RA et al. · 2025 · Surgical neurology international
Background Idiopathic normal pressure hydrocephalus (iNPH) is a benign neurologic condition with treatment response rates ranging only between 30 and 50%. Several studies have attempted to identify clinical or radiological predictive…
View details →DOI: 10.25259/sni_975_2024 Negative / Null Result ReportMedicine
Pelegrín-Mateo FJ, Zambrano CB, Vázquez EB et al. · 2025 · European journal of internal medicine
Cancer-associated thrombosis (CAT) remains a leading cause of morbidity and mortality among oncology patients, with an incidence influenced by tumor type, stage, treatment, and molecular characteristics. This review explores the molecular…
View details →DOI: 10.1016/j.ejim.2025.04.004 Negative / Null Result ReportMedicine
Datta A, Katyayan I, Das KK et al. · 2025 · Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Parent Artery Occlusion (PAO) is a valid treatment choice in giant internal carotid artery (ICA) aneurysms of the cavernous segment when the preoperative balloon test occlusion (BTO) demonstrates an adequate cross circulation from the…
View details →DOI: 10.1016/j.jocn.2025.111044 Negative / Null Result ReportOpen accessMedicine
Stahlmann K, Reitsma JB, Zapf A · 2023 · Statistical methods in medical research
Most diagnostic studies exclude missing values and inconclusive results from the analysis or apply simple methods resulting in biased accuracy estimates. This may be due to the lack of availability or awareness of appropriate methods. This…
View details →DOI: 10.1177/09622802231192954 Negative / Null Result ReportMedicine
Saber Tanha A, Hosseini S, Soltani E et al. · 2025 · Clinical nuclear medicine
Abstract A 47-year-old woman, recently diagnosed with breast cancer, underwent staging. A whole-body bone scan revealed an unexpected focal 99m Tc-MDP uptake in her right ovary. Extensive literature review suggested various malignant…
View details →DOI: 10.1097/rlu.0000000000005606 Negative / Null Result Report
Vezirian K, Beffara B, begue l · 2024 · Preprint
To develop pharmaceutical drugs, people experiment on lab-animals, and a wide variety of factors might predict the involvement into this situation. Using an ultra-realistic protocol mimicking animal research (n = 145), we examined…
View details →DOI: 10.31234/osf.io/ft7xe Negative / Null Result ReportOpen accessMedicine
Dudnyk A, Tytarenko N, Lytvyniuk O et al. · 2026 · Therapeutic advances in infectious disease
Background Patients with multidrug-resistant tuberculosis (MDR-TB) receive treatment that is at least 20% less effective than drug-susceptible cases globally. Objectives The study evaluated the diagnostic accuracy of mfloDx MDR-TB assay…
View details →DOI: 10.1177/20499361261436542 Negative / Null Result ReportMedicine
Mieites V, Fernández-Manteca MG, Santiuste Torcida I et al. · 2025 · Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study explores the potential of conventional Raman spectroscopy and commonly used spectral analysis pipelines for rapid and straightforward assessment of degradation in serum samples resulting from storage delays. Serum samples from…
View details →DOI: 10.1016/j.saa.2025.126297 Negative / Null Result Report
Mwakibete L, Hoarau AOG, Ahyong V et al. · 2024 · Preprint
Investigations of wildlife diseases and mortality events can sometimes lead to inconclusive results due to limitations in diagnostics combined with an ever-increasing number of emerging viruses. The use of tools such as unbiased…
View details →DOI: 10.1101/2024.12.21.629921 Negative / Null Result ReportMedicine
Juutilainen J, Khan MW, Naarala J et al. · 2024 · Occupational and environmental medicine
Objectives Studies assessing the association of adult cancers with extremely low frequency (ELF) magnetic fields (MF) have provided inconclusive results, probably affected by limitations such as low exposure levels, confounding and various…
View details →DOI: 10.1136/oemed-2024-109466 Negative / Null Result Report
Jäggi T, Sato S, Gygax P · 2024 · Preprint
Recently, researchers have started to experimentally investigate the claim that the grammaticalization of the future may impact our mental representations of future events. Yet, this research has mainly focused on the perceived distance of…
View details →DOI: 10.31234/osf.io/4h8gs Negative / Null Result ReportOpen accessMedicine
Hernández-Cuellar E, Tsuchiya K, Medina-Contreras O et al. · 2025 · Journal of clinical medicine
Background/Objectives : Sepsis is a life-threatening condition characterized by an uncontrolled immune response due to systemic infections. It is responsible for millions of deaths worldwide. Although inflammasomes play an important role…
View details →DOI: 10.3390/jcm14197102 Negative / Null Result Report
Teuwen CJ, Vorstermans K, Kusurkar RA et al. · 2024 · Preprint
Interprofessional education is one of the interventions used to increase health care students’ motivation for working with older patients. Previous research about such interventions has been conducted without the use of control groups and…
View details →DOI: 10.12688/mep.19773.2 Negative / Null Result ReportMedicine
Nielsen MK, Bartholdy ID, Kristensen KS et al. · 2025 · Veterinary parasitology
Equine strongylids are ubiquitous and can cause severe health issues. Anthelmintic resistance is widely common in cyathostomin parasites, and recent studies have documented increasing incidence of resistance to the macrocyclic lactone drug…
View details →DOI: 10.1016/j.vetpar.2025.110465 Negative / Null Result ReportMedicine
MacCarrick G, Aradhya S, Bailey M et al. · 2024 · American journal of medical genetics. Part A
Molecular genetics enables more precise diagnoses of skeletal dysplasia and other skeletal disorders (SDs). We investigated the clinical utility of multigene panel testing for 5011 unrelated individuals with SD in the United States…
View details →DOI: 10.1002/ajmg.a.63646 Negative / Null Result ReportOpen accessMedicine
Karvasarski E, Park J, Savaris S et al. · 2026 · CJC open
Background Resting hemodynamic assessment of suspected pulmonary hypertension (PH) in older adults with cardiovascular risk factors may not effectively discriminate pre-capillary from post-capillary disease. Exercise right-heart…
View details →DOI: 10.1016/j.cjco.2026.02.005 Negative / Null Result ReportMedicine
Crabtree D, Seidler K, Barrow M · 2025 · Clinical nutrition ESPEN
Background and aims Epidemiological studies have associated reduced bacterial diversity and abundance and food allergy. This mechanistic review investigated the link between gut dysbiosis and food allergy with a focus on the role of…
View details →DOI: 10.1016/j.clnesp.2024.11.019 Negative / Null Result ReportOpen accessMedicine
Portillo-Gallo JH, Sánchez-González JM, Saldaña-Cruz AM et al. · 2026 · Current issues in molecular biology
Pre-eclampsia is a Hypertensive Disorder of Pregnancy (HDP) characterized by hypertension and proteinuria, affecting 2-8% of pregnancies worldwide and constituting a major public health concern. Genes of the renin-angiotensin system have…
View details →DOI: 10.3390/cimb48020168 Negative / Null Result ReportOpen accessMedicine
Beissat K, Lattard V, Picard-Meyer E et al. · 2025 · PloS one
Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, a wide range of animal species (pets, mink…) have been naturally infected with this betacoronavirus. The emergence of new variants has…
View details →DOI: 10.1371/journal.pone.0316882 Negative / Null Result ReportOpen accessMedicine
Xie J, Jiang Y, Zhou Y et al. · 2024 · Maternal-fetal medicine (Wolters Kluwer Health, Inc.)
Objective To conduct a hierarchical classification analysis of the nonreportable results of noninvasive prenatal testing in an attempt to reduce failure rates and provide pregnant women with accurate information to alleviate their anxiety.…
View details →DOI: 10.1097/fm9.0000000000000248 Negative / Null Result ReportMedicine
Abdo M, Kunisaki KM, Morris A et al. · 2026 · AIDS research and human retroviruses
People aging with HIV (PAWH) experience greater impairment in physical and pulmonary function than individuals aging without HIV. We examined whether baseline physical function was associated with subsequent pulmonary impairments.…
View details →DOI: 10.1177/08892229261448283 Negative / Null Result ReportMedicine
Patchen BK, Best CM, Boiteau J et al. · 2025 · The Cochrane database of systematic reviews
Background Randomised controlled studies evaluating vitamin D supplementation in pregnancy or early childhood for preventing childhood asthma have yielded inconclusive results. Previous systematic reviews of vitamin D for asthma prevention…
View details →DOI: 10.1002/14651858.cd013396.pub2 Negative / Null Result ReportOpen accessMedicine
Lang X, Zhao Y, Zhu Y et al. · 2025 · Risk management and healthcare policy
Background To assess the consequence of different degrees of missing primary endpoint data for randomized controlled trials and to find the influence factors. Methods PubMed, Cochrane Library, EMBASE and ClinicalTrials.gov were searched up…
View details →DOI: 10.2147/rmhp.s511449 Negative / Null Result ReportMedicine
Grillo AR · 2025 · American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Depression is a major public health problem with a continued need to uncover its etiology. Current models of depression contend that gene-by-environment (G × E) interactions influence depression risk, and further, that depression is…
View details →DOI: 10.1002/ajmg.b.33000 