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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 560 of 676

Negative / Null Result Report

Effect of Oxidative Roasting on Selective Leaching of Lithium from Industrially Shredded Lithium Iron Phosphate Blackmass

Tasawar A, Dotto Munchen D, Birich A et al. · 2025 · Preprint

The increasing need-based demand of lithium iron phosphate (LFP) batteries in electric vehicles and energy storage systems necessitates the development of efficient and sustainable recycling methods. This study investigates the effect of…

View details →DOI: 10.20944/preprints202505.1484.v1
Negative / Null Result ReportMedicine

Hyperhomocysteinemia in chronic schizophrenia: prevalence, clinical correlates, and paradoxical associations with symptom severity.

Du J, Jiang R, Liu Y et al. · 2026 · European archives of psychiatry and clinical neuroscience

Background Elevated homocysteine levels, known as hyperhomocysteinemia (HHcy), have been implicated in the pathophysiology of schizophrenia. Most prior studies focused on first-episode or acute-phase schizophrenia patients, leaving the…

View details →DOI: 10.1007/s00406-025-02106-9
Negative / Null Result Report

From leaves to defenders: how the amount and dispersion of leaf damage affect extrafloral nectar production and ant-mediated protection in wild cotton

Ramírez-Delgado VH, Briones-May Y, Garnica-Cabrera A et al. · 2025 · Preprint

Extrafloral nectar (EFN) drives mutualistic interactions between plants and ants. However, EFN production is costly, and its induction is predicted to vary with herbivore-related factors. We examine how the amount and within-plant damage…

View details →DOI: 10.1101/2025.07.31.667819
Negative / Null Result ReportMedicine

Head Acceleration Event Magnitude and Incidence Rate in Academy Rugby Union: A Comparison Across Club and International Competition.

Ward J, Bonnet D, Roumeau M et al. · 2026 · Sports medicine (Auckland, N.Z.)

Background Head acceleration events (HAEs) are an increasing concern in rugby union due to their association with brain injury and long-term neurological health. Objectives This original research study aimed to establish essential baseline…

View details →DOI: 10.1007/s40279-025-02327-x
Negative / Null Result Report

Bumblebees do not prefer consistent floral scents over variable ones

Armand M, Zeilmann L, Weinzettl C et al. · 2025 · Preprint

Abstract To attract pollinators, flowering plants evolve diverse sensory traits into compelling signals. Floral scent, in particular, plays a key role in drawing bees from a distance and shaping their foraging choices. Scent composition…

View details →DOI: 10.21203/rs.3.rs-6292403/v1
Negative / Null Result ReportMedicine

The effects of processing speed and cognitive load demands on working memory performance in young adults born very preterm.

Mills T, Pascoe L, Spencer-Smith M et al. · 2025 · The Clinical neuropsychologist

Objective To examine working memory performance in young adults born very preterm (VP) and full-term (FT) in the context of information processing. Methods A cohort of 118 young adults born VP (mean age 20.1 years) and 48 young adults born…

View details →DOI: 10.1080/13854046.2025.2533300
Negative / Null Result ReportOpen accessMedicine

Indomethacin Fails to Increase Intestinal Permeability in Healthy Volunteers.

Camilleri M, Busciglio I, Carlson P et al. · 2026 · Clinical and translational gastroenterology

Introduction Indomethacin is often used experimentally to induce intestinal hyperpermeability, enabling evaluation of interventions targeting barrier function. Methods We conducted a randomized, double-blind, placebo-controlled study…

View details →DOI: 10.14309/ctg.0000000000000944
Negative / Null Result ReportMedicine

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance.

Williams EP, Harris LN, Moore JS et al. · 2025 · Journal of fish biology

Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult…

View details →DOI: 10.1111/jfb.70206
Negative / Null Result ReportMedicine

Unveiling Incompatibility of High Nickel Cathode With p-xylene Solvent for Facile Wet-Slurry Process in All-Solid-State Batteries.

Kim J, Kim J, Park J et al. · 2025 · Small (Weinheim an der Bergstrasse, Germany)

All-solid-state batteries (ASSBs) are considered one of the most promising next-generation batteries due to their outstanding safety and superior energy density. For the commercial success of ASSBs, developing a scalable wet-slurry-based…

View details →DOI: 10.1002/smll.202406842
Negative / Null Result Report

Bumblebees do not prefer consistent floral scents over variable ones

Armand M, Zeilmann L, Weinzettl C et al. · 2025 · Preprint

ABSTRACT To attract pollinators, flowering plants evolve diverse sensory traits into compelling signals. Floral scent, in particular, plays a key role in drawing bees from a distance and shaping their foraging choices. Scent composition…

View details →DOI: 10.1101/2025.03.15.643418
Negative / Null Result ReportMedicine

Effects of two years of COVID-19 pandemic on individuals with fibromyalgia.

Sahar T, Minerbi A, Pagé MG et al. · 2025 · Clinical and experimental rheumatology

Objectives The COVID-19 pandemic has caused prolonged stress, potentially exacerbating fibromyalgia (FM) symptoms. This study aimed to compare the health status of FM patients and healthy controls (HC) before and 2.5 years into the…

View details →DOI: 10.55563/clinexprheumatol/ide0x0
Negative / Null Result ReportMedicine

"Did I buy that just now?" - Investigating factors influencing the accuracy of food choice self-reports in a simulated online grocery store.

Manzke L, O'Sullivan K, Tiefenbeck V · 2025 · Appetite

Food choices profoundly impact population health and the environment. Related research often relies on self-reported data, which is prone to biases, compromising the accuracy and validity of conclusions about consumer behavior. There are…

View details →DOI: 10.1016/j.appet.2025.108032
Negative / Null Result ReportMedicine

Delivering health care without degrading health: Factors associated with hospital commitment to environmental sustainability.

Ranucci R · 2025 · Health care management review

Background In delivering health care, hospitals contribute to climate change, which adversely impacts human health. Given this paradox, there are mounting efforts to encourage environmental sustainability in hospitals. Purpose With growing…

View details →DOI: 10.1097/hmr.0000000000000439
Negative / Null Result ReportMedicine

Faster bladder filling in rats reduces detrusor overactivity but worsens (i.e., decreases) bladder compliance.

He W, Slavik N, Braun J et al. · 2024 · American journal of physiology. Renal physiology

The impact of bladder filling rate on cystometric outcomes remains unclear. Clinically, faster bladder filling is believed to increase the likelihood of observing detrusor overactivity (DO) in those with bladder dysfunction, although…

View details →DOI: 10.1152/ajprenal.00209.2024
Negative / Null Result ReportMedicine

Evaluating NLP Approaches to Extract Drug Indications.

Sarkar IN · 2026 · AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Reliable drug-indication knowledge is essential for clinical decision support and pharmacovigilance, yet manual curation is labor-intensive and difficult to scale. This study evaluated nine natural language processing approaches to extract…

Negative / Null Result ReportMedicine

Lighting Up MS2: Exploring Fluence Rates for Virus Inactivation

Pousty D, Betzalel Y, Mamane H · 2025 · AWWA Water Science

This study examined the impact of UV‐LED fluence rate (incident irradiance) and wavelengths on the inactivation of MS2 bacteriophage, determined by log reduction value (LRV). Three levels of fluence rates, each differing by an order of…

Negative / Null Result ReportOpen accessMedicine

Reciprocal cross-feeding between bacteria can limit the emergence of metabolic dependencies.

Chuang Y-C, Behringer MG, Patton GE et al. · 2026 · Applied and environmental microbiology

Cross-feeding is prevalent in microbial communities. Through time, cross-feeding is thought to enrich for loss-of-function mutations, thereby creating or reinforcing dependencies between community members. However, few studies have…

View details →DOI: 10.1128/aem.00363-26