Negative / Null Result ReportOpen accessMedicine
Li Z, Hu X, Feng H et al. · 2026 · Animals : an open access journal from MDPI
We evaluated the effects of different levels of DON (LD 441 and HD 1223 μg DON/kg in diet) on the growth performance, immunity, reproductive hormones, and intestinal health of immature gilts. No significant differences were observed in…
View details →DOI: 10.3390/ani16111751 Negative / Null Result ReportMedicine
Fisher JP, Roche J, Duffy AG et al. · 2026 · Autonomic neuroscience : basic & clinical
We investigated whether three days of hypoxic exposure in a hypobaric chamber, and the associated nocturnal periodic breathing (nPB), reduce sympathetic nerve activity (MSNA) transduction to blood pressure (BP). While hypoxia did not…
View details →DOI: 10.1016/j.autneu.2026.103386 Negative / Null Result ReportMedicine
Liu CX, Blair BA, Tenney ER · 2026 · Psychological science
In 2012, Livingston et al. found that Black women were buffered against gender backlash; whether Black women were dominant or supportive toward an employee did not affect people's perceptions of them as leaders in an organization.…
View details →DOI: 10.1177/09567976261436988 Negative / Null Result ReportOpen accessMedicine
Wang L, Sardella BR, Aronson EK et al. · 2026 · NPJ breast cancer
We utilized the K14-Cre Brca1 f/f Tp53 f/f mouse model to investigate whether a pulse of PARP inhibitor (PARPi) ± an AKT inhibitor (AKTi) can prevent Brca1-related breast cancer. PARPi alone did not intercept or prevent tumor development.…
View details →DOI: 10.1038/s41523-026-00892-6 Negative / Null Result ReportMedicine
Yang EH, Lopez C, Shay SL et al. · 2026 · Infection control and hospital epidemiology
The clinical outcomes associated with using commercial versus open ISDTs (initial specimen diverting techniques) remain unclear. This multicenter study showed that switching from the commercial to open ISDT did not change blood culture…
View details →DOI: 10.1017/ice.2026.10412 Negative / Null Result ReportMedicine
Thomas A, Tucker CB, Lunn DE et al. · 2026 · Journal of biomechanics
Studies investigating the concurrent validity of markerless motion capture (MMC) systems for obtaining joint and segment kinematics have largely failed to consider the impact of ambient lighting and camera position, which can both affect…
View details →DOI: 10.1016/j.jbiomech.2026.113343 Negative / Null Result ReportMedicine
Tazumi T, Prados J, Urcelay GP · 2026 · Journal of comparative psychology (Washington, D.C. : 1983)
This study examined whether saline acts as an aversive stimulus for planarians and how it influences learning and memory. Using saline as an unconditioned stimulus, we first tested conditioned place avoidance. Saline did not support…
View details →DOI: 10.1037/com0000449 Negative / Null Result ReportOpen accessMedicine
Sameed M, Meng Z, Marciniak ET · 2019 · Breathe (Sheffield, England)
In the EOLIA trial, early use of ECMO did not significantly improve mortality at 60 days in patients with severe ARDS, but when used as a rescue modality ECMO might help improve survival http://bit.ly/2XOjwSE.
View details →DOI: 10.1183/20734735.0363-2018 Negative / Null Result ReportOpen accessMedicine
Bath PM, Howard G, Hacke W · 2025 · Neurological research and practice
Background The majority of randomised controlled trials in acute stroke and many for prevention are neutral, i.e. they failed to reach statistical significance. However, many of these will find apparent benefit in a component of a…
View details →DOI: 10.1186/s42466-025-00369-0 Negative / Null Result ReportMedicine
Galipienso-Eri M, Baraldés-Canals M, Aliaga-Martínez A et al. · 2025 · Indian journal of orthopaedics
Background/purpose Periprosthetic joint infection (PJI) accounts for up to 25% of failed total knee arthroplasties and 15% of the hips. The ICM18 established the criteria for the diagnosis, and the alpha-defensin lateral flow test (ADLT)…
View details →DOI: 10.1007/s43465-025-01409-2 Negative / Null Result ReportOpen accessMedicine
Saqib K, Goel V, Dubin JA et al. · 2026 · International journal of public health
Objective To examine differences in mental health-related healthcare utilization for anxiety and depression between individuals who did and did not undergo COVID-19 PCR testing in Ontario. Background: The COVID-19 pandemic has been…
View details →DOI: 10.3389/ijph.2026.1609134 Negative / Null Result ReportMedicine
Campo-Beamud C, Roig-Ferreruela G · 2026 · Archivos de la Sociedad Espanola de Oftalmologia
Blue light is a physiological component of visible light, essential for daytime vision and circadian synchronization. There is no evidence supporting the routine use of blue-blocking glasses for preventive or therapeutic purposes. The most…
View details →DOI: 10.1016/j.oftale.2026.502590 Negative / Null Result ReportMedicine
Marder SR, Eriksson H, Zhao Y et al. · 2020 · Acta neuropsychiatrica
Objective We provide a closer look at the result of a randomised, placebo-controlled, active-reference (quetiapine XR), flexible-dose, 6-week study of brexpiprazole in schizophrenia, which did not meet its primary endpoint - change from…
View details →DOI: 10.1017/neu.2020.8 Negative / Null Result ReportMedicine
Shah R, Das S, Gentile Kruse CF et al. · 2025 · Pediatric neurology
Background Triptans are used to treat migraine attacks, but little to no evidence supports their use for youth with post-traumatic headache (PTH). This study evaluated patterns of use and benefit of triptans in the treatment of acute…
View details →DOI: 10.1016/j.pediatrneurol.2025.03.013 Negative / Null Result Report
Eggeling-Böcker M, Karabetsos E, Christopoulou M et al. · 2025 · Preprint
Background: Technological advancements, such as the introduction of the fifth generation technology standard 5G, offer opportunities but also raise concerns. Although no evidence suggests negative effects of radiofrequency electromagnetic…
View details →DOI: 10.12688/openreseurope.19236.2 Negative / Null Result ReportMedicine
Park K, Özgüroğlu M, Vansteenkiste J et al. · 2021 · Lung cancer (Amsterdam, Netherlands)
Objectives The JAVELIN Lung 200 phase 3 trial did not meet its primary endpoint of improving overall survival (OS) with avelumab vs docetaxel in patients with platinum-treated PD-L1+ NSCLC. We report post hoc analyses assessing the effects…
View details →DOI: 10.1016/j.lungcan.2021.01.026 Negative / Null Result ReportMedicine
Ponce H, Cordero R, Tran J et al. · 2025 · Journal of patient experience
In a prior study, communication scholar ratings of clinician communication effectiveness did not correlate with perceived clinician empathy, which is one aspect of patient experience. We repeated the analysis with a different rating of…
View details →DOI: 10.1177/23743735251323674 Negative / Null Result ReportOpen accessMedicine
Neter E, Youngmann R, Gruper N · 2025 · JMIR formative research
Unlabelled Associations between eHealth literacy and mental health literacy were examined; no significant association was identified between overall eHealth and mental health literacy and only weak associations between specific skills were…
View details →DOI: 10.2196/76812 Negative / Null Result ReportOpen accessMedicine
Pienkos S, Swank Z, Hamlin RE et al. · 2025 · Open forum infectious diseases
Plasma samples obtained approximately 3 ( n = 100) and 12 months ( n = 78) after acute SARS-CoV-2 infection were tested for S1, spike, and N antigens. There were no significant differences in plasma proteins or single-cell protein…
View details →DOI: 10.1093/ofid/ofaf515 Negative / Null Result ReportOpen accessMedicine
Wesley CD, Strange JE, Holt A et al. · 2025 · European heart journal open
Aims Fluoroquinolones (FQ) have been associated with aortic aneurysm and aortic dissection (AA/AD) resulting in an official warning. Recently, large-scale epidemiological studies failed to confirm this. Methods and results The current…
View details →DOI: 10.1093/ehjopen/oeaf021 Negative / Null Result ReportOpen access
Physical activity has many health and psychological benefits, however many programs aimed at increasing physical activity have failed to show the expected results. This may be because when people increase their level of exercise, they…
Negative / Null Result ReportOpen access
Growth factors and cytokines have a great potential for regenerative medicine applications. Yet, most of these molecules have failed to show efficacy in humans or raised major safety concerns, due to high dosing and inappropriate delivery…
Negative / Null Result ReportOpen accessMedicine
Demattio L, Fietz D, Schuler G et al. · 2024 · Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
A 9.4 mg deslorelin slow-release implant was inserted into an adult, healthy billy goat to achieve temporary infertility and a reduction in sexual behavior. The implant was inserted in late autumn. No significant change in testis size was…
View details →DOI: 10.1055/a-2289-5640 Negative / Null Result ReportOpen accessChemical technology
Maximilian J. Chmielinski, Martin A. Cohen, Michael G. Yost et al. · 2022 · Sensors
Available wearable dosimeters suffer from spectral mismatch during the measurement of broadband UV and visible radiation in environments that receive radiation from multiple sources emitting differing spectra. We observed this type of multi-spectra environment in all five Washington State cannabis farms visited during a field study investigating worker exposure to ultraviolet radiation in 2018. Spectroradiometers do not suffer from spectral mismatch in these environments, however, an extensive literature review conducted at the time of writing did not identify any spectroradiometers that were
View details →DOI: 10.3390/s22228829 Negative / Null Result ReportOpen accessNursing
Luana Vieira Toledo, Bárbara Xavier dos Santos, Patrícia de Oliveira Salgado et al. · Revista Brasileira de Enfermagem
ABSTRACT Objectives: to compare tympanic and axillary body temperature values of critical patients before and after the traditional and dry bed bath. Methods: this is a randomized, open crossover clinical trial conducted with 50 adult critical patients. All patients received both types of bed bathing. The tympanic and axillary temperature values were measured at the beginning and end of the baths. The Wilcoxon test or paired Student’s t test was used. Results: elderly and male patients predominated. There was no significant difference between tympanic temperature medians measured during the tr
View details →DOI: 10.1590/0034-7167-2020-0969 Negative / Null Result ReportOpen accessPhysiology
Mazen Samie Hassn · 2018 · مجلة الرافدين للعلوم الرياضية
The subject of the research focuses on identifying the differences between the three attempts to test the viability of VC and the contribution of age ratios, and some anthropometric measurements in the best bioenergy test. It also aims to adjust a regression model to predict the biological capacitance in relation to age and some anthropometric variables. The researcher hypothesizes that there are no significant differences between the three tests of the vital capacity, and that the coefficients of the regression model for linear regression equation in the biomass test are not different from ze
View details →DOI: 10.33899/rajsport.2018.163014 Negative / Null Result ReportOpen accessPlant culture
Gy. Horváth, A. Farkas, Gy. L. Szabó · 2004 · International Journal of Horticultural Science
The presence of phloretin-glycosides in the hypanthium and pistil of apple and pear flowers can be verified. Thin layer chromatography is a reliable method for detecting phloretin, gained by acidic hydrolysis. The dominance of phloretin was equally characteristic for flowers in apple (`Sampion', 'Freedom') and pear (Tem-re Bosc', 'Conference') cultivars treated with various bioregulators (Biomit, Bion 50WG, Regalis), no significant difference could be found visually as compared to control samples. Chlorogenic acid and caffeic acid was detected in all apple and pear samples, rutin was present o
View details →DOI: 10.31421/ijhs/10/2/459 Negative / Null Result ReportOpen accessScience
Sang-Suk Choi, Jin Jung, Sung-Ho Her et al. · 2023 · Life
(1) Background: Moderate-intensity statin therapy, when compared to high-intensity statin therapy in Asian populations, has shown no significant difference in cardiovascular prognosis in small studies. The aim of this study was to compare the prognosis of patients based on statin intensity following rotational atherectomy (RA) during high-complexity percutaneous coronary intervention (PCI). (2) Methods: The ROCK registry, a multicenter retrospective study, included patients who had undergone rotational atherectomy (RA) during percutaneous coronary intervention (PCI) at nine tertiary medical ce
View details →DOI: 10.3390/life13112232 Negative / Null Result ReportOpen accessMedicine
LU Yongping, PAN Tingfang · 2025 · Jichu yixue yu linchuang
In order to cultivate interdisciplinary innovative medical talents who can adapt to the development of the needs of national medical care and of global file of medical education, Peking Union Medical College has initiated the project of the “4+4” model, which covers a series of education remodeling like candidate trainees’ enrollment, curriculum integration application of new teaching methods, assessment and evaluation, etc., and has made a great progress. The existing evaluation data show that there is no significant difference between the academic performance of students in the “4+4” trainin
View details →DOI: 10.16352/j.issn.1001-6325.2025.04.0551 Negative / Null Result ReportOpen accessAnimal culture
Samadi F, Sahneh M · 2015 · Poultry Science Journal
A total of 240, one-day-old quail chicks (Coturnix coturnix japonica) were used to study the effects of Artichoke leaf meal (ALM) and vitamin E in diet on growth performance, ileal microbial populations and intestinal morphology in a 42-d trial. This experiment was performed as a completely randomized design with 4 replicates of 15 quails each, using a 4 × 2 factorial arrangement with diet and gender as the main effects. Four dietary treatments were formulated by addition of 2 levels (1.5 and 3 percent) of ALM and 300 mg/Kg vitamin E to the basal diet. Supplementing basal diet with ALM did not
