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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 550 of 676

Negative / Null Result ReportMedicine

The relationships between proprioceptive awareness, balance, and spasticity in patients post-stroke with varying levels of trunk impairment.

Ada G, Duray M · 2026 · Physiotherapy theory and practice

Background Cervical and trunk proprioceptive deficits resulting from impaired sensorimotor integration post-stroke may contribute to deficiencies in balance reactions and tone regulation. Purpose: To examine relationships between cervical…

View details →DOI: 10.1080/09593985.2026.2656807
Negative / Null Result ReportMedicine

Associations between attitudes and beliefs about the role of nutrition and diet quality with pain interference and physical function.

Fredhoff B, Bernstetter A, Fotiou H et al. · 2026 · Complementary therapies in clinical practice

Background and purpose Nutrition likely influences pain, but the role of patient beliefs remains understudied in musculoskeletal conditions. This study examined whether beliefs about the role of nutrition in pain, diet quality, and eating…

View details →DOI: 10.1016/j.ctcp.2026.102057
Negative / Null Result ReportMedicine

Other-Oriented Perfectionism and Romantic Relationship Stress: The Role of Social Media Use Among Italians.

Amodeo AL, Giaquinto V, Reginelli F et al. · 2026 · Psychological reports

The present study examines the associations between other-oriented perfectionism and individual stress within romantic relationships, focusing on the intervening role of social media use as a relational context. Data were collected through…

View details →DOI: 10.1177/00332941261423478
Negative / Null Result Report

Predictive Value of Clinical and Trauma Scores for Life-Saving Interventions in Pediatric Trauma Patients: A Retrospecti̇ve Cohort Study

Güngör E, Birbilen AZ, Yildiz LA et al. · 2026 · Preprint

Abstract Purpose Early identification of pediatric trauma patients requiring life-saving interventions (LSIs) is fundamental for optimizing emergency triage and allocation planning. This study aimed to evaluate and compare the predictive…

View details →DOI: 10.21203/rs.3.rs-9271487/v1
Negative / Null Result ReportMedicine

Factors Contributing to the Depressive Symptoms among Patients Receiving Hemodialysis: A Cross-Sectional Analysis Using the PHQ-9.

Jeremias Macedo M, Beirão B, Rodrigues R et al. · 2026 · Blood purification

Introduction Depression is the most prevalent psychiatric disorder among patients with end-stage renal disease receiving hemodialysis (HD), associated with reduced quality of life, poor treatment adherence, higher hospitalization rates,…

View details →DOI: 10.1159/000551823
Negative / Null Result ReportMedicine

Associations of preoperative patient mental health status, sociodemographic and clinical characteristics with baseline pain, function and satisfaction in patients undergoing revision rotator cuff repairs.

Streubel PN, Sahoo S, Zhang C et al. · 2026 · Journal of shoulder and elbow surgery

Background This study aimed to investigate the associations of general patient and disease-specific factors with baseline patient reported outcome measures (PROMs) in patients undergoing revision rotator cuff repair (RCR). Baseline…

View details →DOI: 10.1016/j.jse.2026.05.007
Negative / Null Result ReportMedicine

Individuals with posttraumatic stress disorder have increased beat-to-beat blood pressure variability.

McGranahan MJ, Sabino-Carvalho JL, Zanuzzi MG et al. · 2026 · American journal of physiology. Regulatory, integrative and comparative physiology

Individuals with posttraumatic stress disorder (PTSD) are at elevated risk for cardiovascular disease (CVD). Emerging research suggests that increased blood pressure variability (BPV) reflects abnormalities in autonomic regulation and may…

View details →DOI: 10.1152/ajpregu.00322.2025
Negative / Null Result ReportOpen accessMedicine

Sexual and bowel function in women with obstetric anal sphincter injuries after perineoplasty and sphincterorrhaphy.

Imantika E, Praharsini RK, Sasotya RM et al. · 2026 · Narra J

Obstetric anal sphincter injury (OASIS) may lead to persistent sexual and bowel dysfunction, even after surgical repair. Evidence on the functional outcomes after sphincterorrhaphy and perineoplasty remains limited, particularly in…

View details →DOI: 10.52225/narra.v6i1.3038
Negative / Null Result ReportMedicine

Risk Factors for Recurrence and Complications Following Cytoreductive Surgery in Platinum-Resistant Ovarian Cancer: A Retrospective Cohort Study.

Wang L, Yao L, Wan J et al. · 2026 · Annali italiani di chirurgia

Aim This study aims to identify independent risk factors for tumor recurrence and postoperative complications in platinum-resistant ovarian cancer patients undergoing cytoreductive surgery. Methods This study retrospectively included 96…

View details →DOI: 10.62713/aic.4351
Negative / Null Result ReportOpen accessMedicine

Associations of circulating resistin with Alzheimer's disease biomarkers and cognitive function in the preclinical stage of Alzheimer's disease.

Eruysal E, Ravdin L, Iadecola C et al. · 2026 · Journal of Alzheimer's disease : JAD

BackgroundResistin is a circulating protein linked to systemic metabolic disorders and inflammation, both of which can contribute to the pathogenesis of Alzheimer's disease (AD). However, the role of resistin during the preclinical stage…

View details →DOI: 10.1177/13872877261442230
Negative / Null Result ReportOpen accessMedicine

Clinical Predictors of Survival After Palliative Radiotherapy for Glioblastoma in a Real-World Cohort Study.

Bock F, Hildebrandt G, Frerker B et al. · 2026 · Current oncology (Toronto, Ont.)

Background This study sought to evaluate overall survival (OS) following palliative radiotherapy in glioblastoma and to identify clinically applicable predictors supporting patient-centred treatment decisions, with exploration of early…

View details →DOI: 10.3390/curroncol33060305
Negative / Null Result ReportOpen accessMedicine

Glycemic trends following hypoglossal nerve stimulation in patients with obstructive sleep apnea and type 2 diabetes.

Ahmed A, Segal S, Gibber M · 2026 · Sleep & breathing = Schlaf & Atmung

Purpose To describe glycemic trends following hypoglossal nerve stimulation (HNS) therapy in patients with obstructive sleep apnea (OSA) and type 2 diabetes. Methods A retrospective review was conducted of patients with type 2 diabetes who…

View details →DOI: 10.1007/s11325-026-03736-6
Negative / Null Result ReportMedicine

The relationship between pre-incarceration related social determinants and glycaemic control in African Americans with criminal legal involvement and type 2 diabetes.

Akinboboye O, Walker RJ, Campbell JA et al. · 2026 · Diabetic medicine : a journal of the British Diabetic Association

Aims To evaluate the relationship between pre-incarceration social determinants, demographic and clinical factors, and glycaemic control in African Americans with a history of criminal legal involvement and type 2 diabetes mellitus.…

View details →DOI: 10.1111/dme.70342
Negative / Null Result ReportMedicine

Surgical Helmet Systems Were Not Associated With Lower Operative Infection Rates After Total Ankle Arthroplasty: A Retrospective Cohort Study.

McCahon JAS, Thomas GM, Hsu A et al. · 2026 · Foot & ankle international

BackgroundConflicting evidence exists regarding the ability of surgical helmet systems (SHSs) to reduce rates of infection after joint replacement. The purpose of this study was to investigate the use of SHS in total ankle arthroplasty…

View details →DOI: 10.1177/10711007261436417
Negative / Null Result ReportMedicine

Can we predict functional recovery following non-operative treatment of proximal humerus fractures?

Hammond B, Goldstein A, Murugesan D et al. · 2026 · Journal of clinical orthopaedics and trauma

Background Functional recovery following non-operative treatment of proximal humerus fractures (PHFs) varies widely, but the relative impact of patient characteristics and medical comorbidities remain unclear. This study aimed to identify…

View details →DOI: 10.1016/j.jcot.2026.103435
Negative / Null Result ReportMedicine

Discharge destination and one-year mortality in acute limb ischemia survivors after revascularization: A multicenter registry study.

Yoshioka N, Hata Y, Haraguchi T et al. · 2026 · Journal of vascular surgery

Objective Acute limb ischemia may impair functional status and hinder return home after hospitalization, even in patients who survive to discharge. However, the associations among discharge destination, clinical characteristics, and…

View details →DOI: 10.1016/j.jvs.2026.04.027
Negative / Null Result ReportMedicine

The Efficacy of 5% Propolis Gel in the Treatment of Primary Herpetic Gingivostomatitis in Children and Its Effect on Salivary IFN-γ Levels: A Parallel Randomized Controlled Pilot Trial.

Shalaby R, Sadek GEM, Gamil Y et al. · 2026 · European journal of dentistry

Objectives This pilot trial was designed to investigate the efficacy of propolis-based gel in the treatment of primary herpetic gingivostomatitis in children and assessed salivary IFN-γ levels before and after treatment to reflect the…

View details →DOI: 10.1055/s-0046-1822966
Negative / Null Result ReportMedicine

Comparison of Knee Extensor Mechanism, Function, and Flexion Range of Motion Between Obese and Nonobese Patients After Simultaneous Bilateral Total Knee Arthroplasty: A Retrospective Follow-up Study.

Bakırhan S, Şahinoğlu E, Ünver B et al. · 2026 · The journal of knee surgery

Abstract Conflicting findings exist regarding the association between obesity and functionality after total knee arthroplasty (TKA). We aimed to compare knee extensor mechanism function, knee function, and knee flexion range of motion…

View details →DOI: 10.1055/a-2886-8345
Negative / Null Result ReportOpen accessMedicine

Health Storylines Mobile Application and Self-management among Chronically Ill Patients: A Quasi-experimental Research Design.

Moreno-Lacalle RC, Agbayani KPG, Alog JR et al. · 2026 · Acta medica Philippina

Background Self-management is crucial for individuals with chronic illnesses. While mobile applications (mAPPs) have emerged to support diverse health needs, evidence regarding their efficacy for self-management among chronically ill…

View details →DOI: 10.47895/amp.vi0.12853
Negative / Null Result ReportOpen accessMedicine

Impact of Post-Curing Exposure Time on the Dimensional Fidelity of 3D-Printed Provisional Crowns: A Root Mean Square (RMS) Evaluation.

Anghel MA, Mitruț I, Ionescu M et al. · 2026 · Journal of functional biomaterials

Background Dimensional stability during post-curing exposure time is critical for the clinical success of 3D-printed restorations. This study evaluates how different post-curing protocols affect the accuracy of provisional crowns. Methods…

View details →DOI: 10.3390/jfb17060263
Negative / Null Result ReportOpen accessMedicine

Impact of a structured case report on self-reported responses to simulated emergency scenarios: a randomized survey-based study.

Porschen C, Hellenthal KEM, Zarbock A et al. · 2026 · Scientific reports

Case reports are a long-standing component of medical research, but their association with self-reported responses to simulated clinical scenarios remains underexplored. This study investigated whether exposure to a structured case report…

View details →DOI: 10.1038/s41598-026-54854-w
Negative / Null Result ReportMedicine

[Efficacy of stapes prosthesis surgery for congenital stapes fixation or oval window atresia in pediatric patients].

Zhang R, Dang PH, Zhou DX et al. · 2026 · Zhonghua yi xue za zhi

Objective: To explore the clinical efficacy of stapes prosthesis surgery for the treatment of congenital fixation of stapes or oval window atresia in pediatric patients. Methods: The clinical data of children with congenital fixation of…

View details →DOI: 10.3760/cma.j.cn112137-20260407-00942
Negative / Null Result ReportMedicine

ANOVA-based comparative study for landfill age and climate impacts on landfill leachate characteristics.

Ergene D, Aksoy A, Sanin FD · 2026 · Environmental monitoring and assessment

This study investigates the combined effects of precipitation and landfill age on leachate characteristics using one-way ANOVA to identify statistically significant differences among impact groups. The primary objective is to evaluate how…

View details →DOI: 10.1007/s10661-026-15577-7