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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19893 results in Negative / Null Result Report · page 547 of 664

Negative / Null Result ReportMedicine

Combined effects of commercial insecticides on survival of the red mason bee Osmia bicornis.

Misiewicz A, Zbrozek M, Laskowski R et al. · 2025 · Ecotoxicology and environmental safety

Insecticides are widely used to control pests, but can also be toxic to ecosystem service providers, including bees. Moreover, their efficacy can increase if they are applied in mixtures. These mixtures can be intentional, e.g., two or…

View details →DOI: 10.1016/j.ecoenv.2025.119023
Negative / Null Result ReportMedicine

Disentangling the effects of environmental and anthropogenic drivers on fungal fruitbody and spore diversity in a Mediterranean coniferous forest

Centenaro G, Ponce Á, de-Miguel S et al. · 2025 · Journal of Environmental Management

Wild macrofungal species are important non-wood forest products in Mediterranean forests, where their ability to release and disperse spores is crucial for completing their life cycle. However, the ecological drivers behind fruitbody…

Negative / Null Result ReportMedicine

How are host-parasite interactions affected by veterinary anti-parasitic treatment? An experimental approach.

Lorrain-Soligon L, Agostini S, Biard C et al. · 2025 · Environmental toxicology and pharmacology

The effects of veterinary anti-parasitic compounds on wild fish species and their parasites are poorly investigated. Bithionol, an antibacterial, anthelmintic, and algaecide, is commonly used in aquaculture to control parasitic infections,…

View details →DOI: 10.1016/j.etap.2025.104782
Negative / Null Result ReportMedicine

Audit and feedback: effects on professional practice.

Ivers N, Yogasingam S, Lacroix M et al. · 2026 · The Cochrane database of systematic reviews

Background Audit and feedback (A&F) is a widely used strategy to improve professional practice. This is supported by prior Cochrane reviews and behavioural theories describing how healthcare professionals are prompted to modify their…

View details →DOI: 10.1002/14651858.cd000259.pub5
Negative / Null Result ReportOpen accessMedicine

Is Religious Coping a Protective Factor, and for Whom? A Moderation and Subgroup Analysis on Loneliness and Suicide Attempts Among LGBTQ+ Adults Raised as Latter-Day Saints.

Kim S, Lefevor GT, Miller CK et al. · 2026 · Suicide & life-threatening behavior

Introduction LGBTQ+ adults face elevated rates of loneliness and suicide attempts, yet little research has examined whether religious coping-a protective factor for people generally-effectively mitigates these risks for LGBTQ+ adults…

View details →DOI: 10.1111/sltb.70088
Negative / Null Result ReportMedicine

A comparison of transduction efficiency of medial septal neurons by adeno-associated viruses with three promoters.

Koryagina AA, Dobryakova YV, Gerasimov KA et al. · 2025 · Journal of neuroscience methods

Background Most researchers rely on popular promoters like the synthetic CAG promoter or human synapsin promoter to transduce various brain neurons. However, their effectiveness in transducing forebrain cholinergic neurons remains unclear.…

View details →DOI: 10.1016/j.jneumeth.2025.110570
Negative / Null Result ReportOpen accessMedicine

The Effect of Stereotype Threat on Aggressive Reactions.

Fourgassie L, Subra B, Sanitioso RB · 2026 · International journal of psychology : Journal international de psychologie

Two studies investigated the impact of stereotype threat on aggressive reactions. Female participants performed a working memory task under a stereotype threat or a control condition. Following this task, they had the opportunity to…

View details →DOI: 10.1002/ijop.70203
Negative / Null Result Report

Effect of Oxidative Roasting on Selective Leaching of Lithium from Industrially Shredded Lithium Iron Phosphate Blackmass

Tasawar A, Dotto Munchen D, Birich A et al. · 2025 · Preprint

The increasing need-based demand of lithium iron phosphate (LFP) batteries in electric vehicles and energy storage systems necessitates the development of efficient and sustainable recycling methods. This study investigates the effect of…

View details →DOI: 10.20944/preprints202505.1484.v1
Negative / Null Result ReportMedicine

Hyperhomocysteinemia in chronic schizophrenia: prevalence, clinical correlates, and paradoxical associations with symptom severity.

Du J, Jiang R, Liu Y et al. · 2026 · European archives of psychiatry and clinical neuroscience

Background Elevated homocysteine levels, known as hyperhomocysteinemia (HHcy), have been implicated in the pathophysiology of schizophrenia. Most prior studies focused on first-episode or acute-phase schizophrenia patients, leaving the…

View details →DOI: 10.1007/s00406-025-02106-9
Negative / Null Result Report

From leaves to defenders: how the amount and dispersion of leaf damage affect extrafloral nectar production and ant-mediated protection in wild cotton

Ramírez-Delgado VH, Briones-May Y, Garnica-Cabrera A et al. · 2025 · Preprint

Extrafloral nectar (EFN) drives mutualistic interactions between plants and ants. However, EFN production is costly, and its induction is predicted to vary with herbivore-related factors. We examine how the amount and within-plant damage…

View details →DOI: 10.1101/2025.07.31.667819
Negative / Null Result ReportMedicine

Head Acceleration Event Magnitude and Incidence Rate in Academy Rugby Union: A Comparison Across Club and International Competition.

Ward J, Bonnet D, Roumeau M et al. · 2026 · Sports medicine (Auckland, N.Z.)

Background Head acceleration events (HAEs) are an increasing concern in rugby union due to their association with brain injury and long-term neurological health. Objectives This original research study aimed to establish essential baseline…

View details →DOI: 10.1007/s40279-025-02327-x
Negative / Null Result Report

Bumblebees do not prefer consistent floral scents over variable ones

Armand M, Zeilmann L, Weinzettl C et al. · 2025 · Preprint

Abstract To attract pollinators, flowering plants evolve diverse sensory traits into compelling signals. Floral scent, in particular, plays a key role in drawing bees from a distance and shaping their foraging choices. Scent composition…

View details →DOI: 10.21203/rs.3.rs-6292403/v1
Negative / Null Result ReportMedicine

The effects of processing speed and cognitive load demands on working memory performance in young adults born very preterm.

Mills T, Pascoe L, Spencer-Smith M et al. · 2025 · The Clinical neuropsychologist

Objective To examine working memory performance in young adults born very preterm (VP) and full-term (FT) in the context of information processing. Methods A cohort of 118 young adults born VP (mean age 20.1 years) and 48 young adults born…

View details →DOI: 10.1080/13854046.2025.2533300
Negative / Null Result ReportOpen accessMedicine

Indomethacin Fails to Increase Intestinal Permeability in Healthy Volunteers.

Camilleri M, Busciglio I, Carlson P et al. · 2026 · Clinical and translational gastroenterology

Introduction Indomethacin is often used experimentally to induce intestinal hyperpermeability, enabling evaluation of interventions targeting barrier function. Methods We conducted a randomized, double-blind, placebo-controlled study…

View details →DOI: 10.14309/ctg.0000000000000944
Negative / Null Result ReportMedicine

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance.

Williams EP, Harris LN, Moore JS et al. · 2025 · Journal of fish biology

Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult…

View details →DOI: 10.1111/jfb.70206
Negative / Null Result ReportMedicine

Unveiling Incompatibility of High Nickel Cathode With p-xylene Solvent for Facile Wet-Slurry Process in All-Solid-State Batteries.

Kim J, Kim J, Park J et al. · 2025 · Small (Weinheim an der Bergstrasse, Germany)

All-solid-state batteries (ASSBs) are considered one of the most promising next-generation batteries due to their outstanding safety and superior energy density. For the commercial success of ASSBs, developing a scalable wet-slurry-based…

View details →DOI: 10.1002/smll.202406842
Negative / Null Result Report

Bumblebees do not prefer consistent floral scents over variable ones

Armand M, Zeilmann L, Weinzettl C et al. · 2025 · Preprint

ABSTRACT To attract pollinators, flowering plants evolve diverse sensory traits into compelling signals. Floral scent, in particular, plays a key role in drawing bees from a distance and shaping their foraging choices. Scent composition…

View details →DOI: 10.1101/2025.03.15.643418
Negative / Null Result ReportMedicine

Effects of two years of COVID-19 pandemic on individuals with fibromyalgia.

Sahar T, Minerbi A, Pagé MG et al. · 2025 · Clinical and experimental rheumatology

Objectives The COVID-19 pandemic has caused prolonged stress, potentially exacerbating fibromyalgia (FM) symptoms. This study aimed to compare the health status of FM patients and healthy controls (HC) before and 2.5 years into the…

View details →DOI: 10.55563/clinexprheumatol/ide0x0
Negative / Null Result ReportMedicine

"Did I buy that just now?" - Investigating factors influencing the accuracy of food choice self-reports in a simulated online grocery store.

Manzke L, O'Sullivan K, Tiefenbeck V · 2025 · Appetite

Food choices profoundly impact population health and the environment. Related research often relies on self-reported data, which is prone to biases, compromising the accuracy and validity of conclusions about consumer behavior. There are…

View details →DOI: 10.1016/j.appet.2025.108032