A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19893 results in Negative / Null Result Report · page 546 of 664
Lesoinne P, Korczewski F · 2025 · Revue medicale de Liege
Ocular metallosis is a rare ophthalmologic condition characterized by alterations of all intraocular structures in the setting of a metallic intraocular foreign body. There are two main types: ocular siderosis - the most frequent and most…
Dutta S, Shenoy P, Varadhan S · 2025 · Preprint
Everyday interactions with objects depend on keeping the grasped item in static equilibrium by effectively distributing the contact forces from the fingertips. The mechanical advantage hypothesis (MAH) proposes that the central nervous…
Harper MM, Jones MG, Gramlich OW et al. · 2026 · Experimental eye research
Traumatic brain injury from blast exposure (bTBI) has been shown to cause functional and structural retinal ganglion cell (RGC) damage. Previous studies have shown the immune system is activated following blast exposure and that adoptive…
Yılmaz MC, Tezer P, Olgaç G et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Background Spinal tumors constitute approximately 15% of all primary central nervous system neoplasms, with extradural tumors accounting for the majority. Ganglioneuromas are rare, benign tumors of neural crest origin, most often located…
Morais JVS, Oliveira TRd, Moura ACMd et al. · 2026 · Preprint
Cowpea (Vigna unguiculata) is a crop of major socioeconomic importance in Northern and Northeastern Brazil, but its productivity is strongly constrained by infestations of the black aphid Aphis craccivora, which causes direct damage…
Dasmeh U, Mohammadi AA, Shahrokhi R et al. · 2025 · Journal of wound care
Objective This study aimed to investigate whether application of autologous platelet-rich plasma (PRP) at split-thickness skin grafting (STSG) donor sites in patients with burns can promote wound healing. Method A randomised crossover…
Lin YS, Hung CC · 2025 · Microsurgery
Introduction Peroneal artery-based free flaps, including fibula and peroneal flaps, are commonly used in reconstructive surgeries. Despite their clinical utility, donor site morbidity remains a concern. Elastography is a non-invasive…
Hando BR, Rhon DI, Barker D et al. · 2026 · The Journal of orthopaedic and sports physical therapy
OBJECTIVE: To determine the effect on Shoulder Pain and Disability Index (SPADI) scores of adding dry needling to a program of exercise and manual therapy in individuals with subacromial pain syndrome (SAPS). DESIGN: Three-arm randomized…
Liang C, He J · 2025 · Journal of Visualized Experiments
Autografts are always used in anterior cruciate ligament (ACL) reconstruction. Traditional sources, such as hamstring tendons, bone-patellar tendon-bone, and quadriceps tendon, are popular choices but may result in muscle imbalances and…
Marean-Reardon CL, Reardon PN, Mortimer NT · 2025 · Preprint
Many insect species use self-medication, the consumption of an environmental compound with antipathogen activity, as a defense against pathogen infection. One well-studied example is the interaction between Drosophila melanogaster and…
Bailhache M, El-Khoury F, Chazelas E et al. · 2026 · Academic pediatrics
Objective To determine the association between parental psychological intimate partner violence (IPV) before and around the time of the child's birth, and their use of an emergency department (ED) and hospitalization from 2 months to 10…
Conceicao D, Helayel P, Garcia J et al. · 2025 · Preprint
Abstract Background: Midshaft clavicular fractures account for approximately 5% of bone fractures. Surgical correction is often necessary to ensure adequate functional recovery. There is no consensus in the literature on which Regional…
Türkiş NA, Taşdemir N · 2026 · Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
Purpose Postoperative nausea and vomiting (PONV) is one of the most common complications in surgical patients during the first 24 hours after general anesthesia. This research aimed to evaluate the effect of cold application on early PONV…
Kazensky L, Lovrić Štefiček MJ, Kašuba V et al. · 2026 · Environmental research
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous air pollutants, where their genotoxic potential raises significant public health concerns. This study evaluated the cytotoxic and genotoxic effects of an environmentally relevant…
McCullen MN, Zerger HM · 2025 · Journal of applied behavior analysis
Previous research supports behavioral interventions, such as contingency management, to increase physical activity. A common limitation of these interventions is a lack of maintenance effects or assessment of the target behavior following…
Zhao Z, Fang Y, Xu G et al. · 2026 · Drug discoveries & therapeutics
This pilot study investigated the protective effect of transfecting brain-derived neurotrophic factor (BDNF) and B-cell lymphoma 2 (bcl-2) genes in retinal ganglion cells (RGCs) using in vivo electroporation in an adult rat optic nerve…
Jabba SV, Erythropel HC, Anastas PT et al. · 2025 · Preprint
Background Since late 2022, the sale of most flavoured tobacco products has been prohibited in California, including menthol cigarettes. Tobacco companies responded by introducing “non-menthol” cigarettes in which menthol was replaced with…
Beeck WV, Lemos M, Niesen AM et al. · 2025 · Preprint
Cephalosporins and other broad-spectrum antibiotics are frequently administered prophylactically into the udder when dairy cows end their lactation cycle, termed dry-off, to reduce mastitis risk. However, the use of antibiotics on cows…
Testa EJ, Fallon RT, Badida R et al. · 2026 · The American journal of sports medicine
Background Posterior glenoid reconstruction for shoulder instability is commonly performed with distal tibia allograft (DTA), but with variable results. Recent evidence shows that distal radius allograft (DRA) has a radius of curvature…
Raposo SR, Lopes RP, Barbosa LF et al. · 2026 · Archives of medical research
Objective To address the major public health problems of increased body weight and obesity, causing conditions such as hypertension and diabetes. Early obesity in childhood and adolescence has more severe long-term health consequences. The…
Israeli R, Steinmetz C, Gannot G et al. · 2026 · Cureus
Introduction Transverse carpal ligament (TCL) release is the standard treatment for carpal tunnel syndrome; however, its potential to alter carpal biomechanics is unclear. Specifically, it has been hypothesized that TCL transection may…
Janssen JC, Schurink AW, Verhoef C et al. · 2026 · European journal of cancer (Oxford, England : 1990)
Background Adjuvant systemic therapy for resected stage III melanoma was introduced in clinical practice following the improved recurrence free survival in randomized controlled trials. However, after ten years of follow-up, adjuvant…
Liang C, He J · 2025 · Journal of visualized experiments : JoVE
Autografts are always used in anterior cruciate ligament (ACL) reconstruction. Traditional sources, such as hamstring tendons, bone-patellar tendon-bone, and quadriceps tendon, are popular choices but may result in muscle imbalances and…
Grewal RS, Berger GK, Pennock AT et al. · 2026 · Journal of pediatric orthopedics
Background Patellofemoral instability is common in adolescent patients and is frequently associated with increased tibial tuberosity-trochlear groove (TT-TG) distances. Medial patellofemoral ligament (MPFL) reconstruction is a standard…
Morey J, Yu J, Brockley L · 2026 · Australian veterinary journal
Introduction Stromal sarcomas are rare canine primary splenic tumors. Previous studies assessing outcomes in dogs with these tumors are limited by small sample sizes, with few dogs receiving adjuvant therapy, leaving the role of…
Santaularia N, Arnau A, Torà N et al. · 2026 · Journal of cardiopulmonary rehabilitation and prevention
Purpose Our purpose was to assess the efficacy of a phase III cardiac rehabilitation (CR) program, based on counseling in the maintenance of physical exercise, on the time spent on physical exercise per week in patients with ischemic heart…
Potten S, Li Z, Cohen E et al. · 2025 · Foot (Edinburgh, Scotland)
Introduction Calcaneal fractures present significant treatment challenges due to their complex anatomy and load-bearing function. Increasingly, minimally invasive techniques are used in treatment. This study evaluates the biomechanical…
Nuyen BA, Kruglik CP, Wang A et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
Objective Patient satisfaction scores, especially the "likelihood to recommend" (LTR) a provider, are becoming increasingly important as measures of surgical quality. In this study, we examined the influence of a surgeon's vocal pitch and…
Saravia DH, Silvan YA, Martinez JI · 2025 · Preprint
Abstract Despite similar rates of mental illness, non-Latinx Whites received care at higher rates compared to Latinxs (NIMH, 2024). Latinx adults report lower mental health literacy (MHL) and higher stigma compared to NLW, which can…
Kulbida M, Kemps E, Tiggemann M · 2026 · Appetite
Excessive soft drink and alcohol consumption have been associated with negative health outcomes. This study tested whether an intervention to reduce preferences for smaller, immediate rewards over larger, delayed rewards (i.e., delay…