Negative / Null Result Report
Holstein R, Hongisto M, Jämsen E et al. · 2026 · Preprint
Abstract Background. Polypharmacy and potentially inappropriate medication (PIM) use are well-known risk factors for drug-related problems among older adults, but their association with clinical outcomes of older emergency department (ED)…
View details →DOI: 10.21203/rs.3.rs-9326583/v1 Negative / Null Result ReportMedicine
Ishimoto K, Narita T, Sekine Y et al. · 2026 · Urologic oncology
Objective To evaluate whether the EV-ineligible criteria (EVITA) are associated with severe adverse events (AEs) and early treatment discontinuation in patients with locally advanced or metastatic urothelial carcinoma (la/mUC) treated with…
View details →DOI: 10.1016/j.urolonc.2026.05.025 Negative / Null Result ReportMedicine
Kristoffersen SF, Domazet SL, Pouwer F et al. · 2026 · Diabetes research and clinical practice
Aims We investigated longitudinal, bidirectional associations between objectively measured moderate to vigorous physical activity (MVPA), health-related quality of life (HRQoL), and emotional well-being (EWB) in individuals recently…
View details →DOI: 10.1016/j.diabres.2026.113185 Negative / Null Result ReportMedicine
Muir MT, Noll K, Patel R et al. · 2026 · Journal of neurosurgery
Objective For patients with language-eloquent brain tumors, surgeons must maximize the extent of resection while minimizing neurological morbidity. Despite the extensive use of noninvasive brain mapping techniques, it remains unclear how…
View details →DOI: 10.3171/2025.6.jns242301 Negative / Null Result Report
KARAASLAN F, BİNBAŞIOĞLU DD, ÇEKİÇ EC et al. · 2026 · Preprint
Abstract Objective To assess long-term outcomes of immediate implant placement in endodontic, periodontal and endo–perio compromised sockets and in sites immediately replaced after failed implant explantation, and to examine the roles of…
View details →DOI: 10.21203/rs.3.rs-9259324/v1 Negative / Null Result Report
White CJM, Muthukrishna M · 2026 · Preprint
Behavioral scientists increasingly recruit participants from less-WEIRD societies, but continue to oversample highly educated people, such as university students and online workers. Here we test how representative highly educated…
View details →DOI: 10.31234/osf.io/8wr5d_v3 Negative / Null Result ReportMedicine
Noroozi Gilandehi S, Shoubash L, Leyendecker J et al. · 2026 · Journal of neurosurgery. Spine
Objective Although patients often report improvements in pain and functional capacity after endoscopic lumbar spine surgery, objectively measured real-life physical activity may differ from that reported. This multicenter prospective study…
View details →DOI: 10.3171/2026.1.spine25926 Negative / Null Result ReportMedicine
Yoo SW, Ryu DW, Oh Y et al. · 2026 · Journal of movement disorders
Background The thyroid gland receives sympathetic innervation. 123I-meta-iodobenzylguanidine (123I-MIBG) is a noradrenaline analog taken up by adrenergic nerve terminals. Although thyroid uptake can be seen on 123I-MIBG scintigraphy, its…
View details →DOI: 10.14802/jmd.26046 Negative / Null Result ReportMedicine
Sullivan AJ, Whalen M, Cooper SE et al. · 2026 · Biological psychology
Fear conditioning research can provide insight into how individuals with clinically relevant traits learn to distinguish between threatening and safe stimuli. Prior studies have found higher anxiety symptoms to be associated with increased…
View details →DOI: 10.1016/j.biopsycho.2026.109282 Negative / Null Result ReportOpen accessMedicine
Korbmacher M, Myhr KM, Wergeland S et al. · 2026 · Frontiers in neurology
Objective To replicate and extend recent findings, suggesting that higher serum alpha-linolenic acid (ALA) levels are associated with reduced disease activity and progression in multiple sclerosis (MS). Methods We reanalysed clinical trial…
View details →DOI: 10.3389/fneur.2026.1796427 Negative / Null Result ReportMedicine
Tabullo ÁJ · 2026 · Trends in neuroscience and education
Background Neuromyths-misconceptions arising from misinterpretations of neuroscientific findings-are widely endorsed by educators and students, including those in psychology. Their persistence has been linked to contextual, cognitive, and…
View details →DOI: 10.1016/j.tine.2026.100284 Negative / Null Result ReportMedicine
Munsch MA, Nguyen DM, Crowley S et al. · 2026 · Hand (New York, N.Y.)
Background This study evaluated the results of minimally invasive headless compression screw (HCS) fixation for treatment of scaphoid delayed union or nonunion. A minimally invasive approach has several potential benefits, including…
View details →DOI: 10.1177/15589447261437823 Negative / Null Result ReportMedicine
Joffe AR, Humber A, Bates A et al. · 2026 · Antimicrobial agents and chemotherapy
Achieving antibiotic pharmacodynamic targets is critical to surviving sepsis. The purpose of this study was to determine the achievement of pharmacodynamic target-free minimum plasma concentration (fCmin)-during the first 2 days of…
View details →DOI: 10.1128/aac.01968-25 Negative / Null Result Report
Howard MM, Bolin LG, Bogar GD et al. · 2026 · Preprint
ABSTRACT Microbial communities can shift under drought in ways that enhance plant performance during drought (“microbe-mediated acclimation”). However, it is also possible for microbial communities to shift in ways that worsen the effects…
View details →DOI: 10.64898/2026.04.02.715620 Negative / Null Result Report
Bading KC, Béna J, Barth M et al. · 2026 · Preprint
Evaluative conditioning (EC) refers to a change in the evaluation of a conditioned stimulus (CS) following its pairing with a positive or negative unconditioned stimulus (US). Theories of EC commonly assume that such effects depend on…
View details →DOI: 10.31234/osf.io/twuh4_v1 Negative / Null Result ReportMedicine
Gomez-Suarez R, Lin E, Gershon E et al. · 2026 · Journal of pediatric gastroenterology and nutrition
Objectives To evaluate the clinical utility of the simplified colon transit protocol of radiopaque markers (SROM) in pediatric functional constipation (FC). Methods Retrospective study of children meeting Rome IV criteria for FC undergoing…
View details →DOI: 10.1002/jpn3.70428 Negative / Null Result ReportMedicine
Jang M, Lee KH, Shin J et al. · 2026 · Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Adolescent depression differs from adult depression in neurobiology and treatment response. Although resting-state functional connectivity (rsFC) of the default mode network (DMN) has been linked to treatment response in adults, its value…
View details →DOI: 10.1038/s41386-026-02442-x Negative / Null Result ReportMedicine
Perkins ER, Flum MW, Plate RC et al. · 2026 · Journal of personality disorders
Psychopathy involves disruptions in affiliation and threat sensitivity, but these are hard to disentangle behaviorally. This preregistered study (independent sample N s = 175 and 173) used clinical-forensic and transdiagnostic measures…
View details →DOI: 10.1521/pedi.2026.40.2.166 Negative / Null Result ReportOpen accessMedicine
Grossmann T, Miller H, Allison O · 2026 · Developmental science
Positive affect (PA) is integral to health and development, yet its early origins remain largely unexplored. In this pre-registered study (N = 78), we investigated whether infant-specific biological and social-behavioral factors predict PA…
View details →DOI: 10.1111/desc.70192 Negative / Null Result ReportOpen accessMedicine
Zournatzidis P, Vorria P, Krana E et al. · 2026 · Personality and mental health
Mentalizing is a socio-cognitive capacity that develops within early attachment relationships, but institutional care may disrupt this process. Although adoption significantly improves developmental outcomes, it remains unclear whether…
View details →DOI: 10.1002/pmh.70084 Negative / Null Result ReportMedicine
Kumar AA, Lim HL, Saffari SE et al. · 2025 · Journal of neurotrauma
Acute traumatic central cord syndrome (ATCCS) is the most common form of incomplete spinal cord injury. Treatment recommendations for ATCCS patients are largely from North America, and their applicability to Asian populations remains…
View details →DOI: 10.1177/08977151251406611 Negative / Null Result ReportMedicine
Cakici O, Aykac K, Seyrek BE et al. · 2026 · The American journal of tropical medicine and hygiene
Tularemia is a rare zoonotic infection with marked geographic clustering and long interepidemic periods. Pediatric data, particularly those on host immune responses during active disease and treatment, remain scarce. The authors aimed to…
View details →DOI: 10.4269/ajtmh.26-0084 Negative / Null Result ReportMedicine
Dunn CB, Farrell AD · 2026 · Research on child and adolescent psychopathology
Prior research has identified externalizing and internalizing pathways to adolescent-onset substance use, but few studies have considered how psychopathology is associated with the development of polysubstance use during early adolescence.…
View details →DOI: 10.1007/s10802-026-01451-0 Negative / Null Result ReportMedicine
Anderson AJ, Rodriguez CM, Henson JM · 2026 · Child psychiatry and human development
Parental psychological distress is a commonly examined risk factor for the emergence of child problem behaviors, but the factors that contribute to that relationship-such as limited parental resources like greater social support and coping…
View details →DOI: 10.1007/s10578-026-01997-6 Negative / Null Result ReportMedicine
Cronblad IA, Warvik CE, Bjerkli IH et al. · 2026 · Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Background Oral tongue squamous cell carcinomas (OTSCC) frequently metastasise via lymphatic vessels, thus lymphangiogenesis may enhance tumour cell dissemination by increasing tumour-lymphatic interactions. The prognostic significance of…
View details →DOI: 10.1111/jop.70148 Negative / Null Result Report
Chen YA, Lind MN, Ram N et al. · 2026 · Preprint
Concerns about adolescent screen time have fueled debates about the role of mobile phone use in adolescent development, yet most research has relied on cross-sectional self-reports and global measures of use. The present study advances the…
View details →DOI: 10.31234/osf.io/5d67p_v1 Negative / Null Result ReportMedicine
Pfeiffer JP, Pinquart M, Neubauer BA · 2026 · Epilepsy & behavior : E&B
Objective Using strategies for achieving age-specific goals is essential for developmental regulation. In a previous study, we demonstrated that adolescents with epilepsy have difficulty achieving some of their goals, which necessitates…
View details →DOI: 10.1016/j.yebeh.2026.110971 Negative / Null Result ReportOpen accessMedicine
Balousis P, Abood SK, Brazeau L et al. · 2026 · Frontiers in veterinary science
Introduction Raw meat-based diets (RMBD) are increasingly popular among dog guardians, yet the role of personal nutrition habits and pet-guardian relationships in their adoption remains unclear. This study examines how these factors,…
View details →DOI: 10.3389/fvets.2026.1793754 Negative / Null Result Report
Voorhorst A, Pouzot-Nevoret C, Vernooij JC et al. · 2026 · Preprint
Intravenous lipid therapy (ILE) is used to treat neurotoxicosis in companion animals, but clinical evidence for in vivo xenobiotic partitioning and benefit remains limited. This study evaluated associations between the log n-octanol/water…
View details →DOI: 10.20944/preprints202602.1330.v1 Negative / Null Result Report
Wong BWL, Samuel AG, Kapnoula EC · 2026 · Preprint
Speech perception consistency refers to the extent to which listeners provide similar responses to repeated presentations of the same speech sound (e.g., along a /ba/–/pa/ continuum). Although recent research has demonstrated multiple…
View details →DOI: 10.31234/osf.io/gxmnr_v1 