A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19893 results in Negative / Null Result Report · page 544 of 664
Hshieh TT, Kunicki ZJ, Fong TG et al. · 2026 · JAMA internal medicine
Importance Postoperative delirium is associated with long-term cognitive decline in older adults. This might be caused by the delirium itself or because delirium is more common in persons who are ill and frail, and these conditions are…
Anwar S, Younas R, Iqbal M et al. · 2026 · Clinical psychology & psychotherapy
Obsessive-compulsive disorder (OCD) is a heterogeneous condition characterized by a wide range of symptoms and maladaptive beliefs. However, previous research has often studied these symptoms and metacognitive beliefs in isolation,…
Tokushige A, Akasaki Y, Shibata K et al. · 2026 · Preprint
Background: /Objectives: We aimed to evaluate the efficacy and safety of trigonelline-rich Sakurajima radish on vascular endothelial function in patients with metabolic syndrome (MetS). Methods: In this multicenter, open-label, randomized,…
Bielen T · 2025 · Preprint
Conversational AI holds promise for scalable mental health screening, yet its impact on therapeuticalliance and user perceptions remains underexplored. This preregistered, cross-sectional, randomizedmixed-methods experiment (N = 149)…
Kim SK, Shin JH, Ji YJ et al. · 2026 · Journal of hazardous materials
Estuarine-coastal regimes are critical links between land and the open ocean, yet their role as microplastics (MPs) sinks and the mechanisms governing MP retention remain poorly constrained. We conducted a coupled water-sediment survey in…
Omer AA, Abdelaziz MO, Bashir RE et al. · 2026 · Preprint
Abstract Background Diabetes and hypertension constitute a dual public health burden, particularly in low-income countries. While urban-rural disparities in healthcare access are well documented, this study aims to compare the prevalence,…
Commauda S, Maglieri V, Prato-Previde E et al. · 2026 · Animals : an open access journal from MDPI
Dogs exhibit sophisticated interspecific communication skills, including the use of visual signals to indicate the location of inaccessible resources, known as showing behaviour. Previous studies have investigated factors such as age and…
Kara D, Bohn A · 2026 · Memory (Hove, England)
The present study investigated whether remembering the distant versus the recent personal past influences self-continuity levels and expected future event characteristics in a sample of immigrants. Seventy-three Turkish immigrants living…
Mądziel M, Campisi T · 2026 · Preprint
Plug-in hybrid electric vehicles (PHEVs) are critical to the EU s decarbonization strategy, yet their real-world climate benefits remain uncertain. This study presents a large-scale analysis of real-world PHEV performance using on-board…
Ivanov S, Fosse S, dos Reis M et al. · 2026 · Preprint
Bayesian inference of divergence times for extant species using molecular data is an unconventional statistical problem: Divergence times and molecular rates are confounded, and only their product, the molecular branch length, is…
Thong S, Hendrikse J, Chong TT- et al. · 2026 · Preprint
Motor and episodic memories are classically conceptualised as distinct memory domains. However, both memory sequences are characterised by order and timing of their elements. Generalisation has been previously documented between these…
Giovenco D, Rousseau E, Wallace M et al. · 2026 · AIDS (London, England)
Objective To examine associations between mental health, substance use, and pre-exposure prophylaxis (PrEP) persistence among South African adolescent girls and young women (AGYW). Design A longitudinal analysis of a decentralized PrEP…
Visser K, Keulen J, Bodden D et al. · 2026 · Journal of autism and developmental disorders
Purpose In clinical practice and research, there is growing interest in transdiagnostic interventions, such as Acceptance and Commitment Therapy (ACT), for patients with autism spectrum disorder (ASD), due to the pervasive nature of the…
Hong W, Jung H · 2026 · Behavioral sciences (Basel, Switzerland)
This study examines how structured interventions influence team creativity on a metaverse-based collaboration platform. Using B.sket, a custom virtual workspace, we tested two interventions during an online brainstorming task: (1)…
Rashidi Y, Maurer F, Wrublewsky S et al. · 2026 · Biophysical journal
Bifurcations are a crucial part of the mammalian microvasculature, as they establish the interface between blood and tissue. The flexibility of red blood cells (RBCs), the main cellular constituent of blood, is believed to strongly impact…
Manzoor A, Allen G, Havelaar AH et al. · 2026 · Journal of food protection
Sous vide cooking is increasingly adopted in both food service and domestic settings due to its ability to deliver precise temperature control and consistent quality. However, food safety remains a critical concern, particularly regarding…
Ishizawa H, Umemoto R, Yoshida N et al. · 2026 · Preprint
ABSTRACT Plants are colonized by characteristic microbiomes that help maintain plant health and function. However, the mechanisms that make these communities assemble in a consistent, repeatable manner remain poorly understood. Here, we…
Liu Y, Ju L, Shi L et al. · 2026 · Preprint
Abstract Previous studies have established that metabolic dysfunction-associated steatotic liver disease (MASLD) disrupts the intestinal barrier, allowing harmful microbial metabolites such as lipopolysaccharide (LPS) to translocate to the…
Fernandes S, Algarra M, Brandão ATSC et al. · 2026 · Nanoscale
While heteroatom doping is widely used to enhance the fluorescence of carbon dots, the actual mechanism underlying this claimed enhancement remains unclear. Herein, we report a systematic comparison between nitrogen-doped carbon dots…
Moreno-Ayala V, Medina-Sánchez JM, Zambrano AF et al. · 2026 · Ecotoxicology and environmental safety
The increasing production of plastics worldwide is a growing source of emerging contaminants, particularly bisphenol A (BPA), a major chemical additive in plastics that, as waste, ends up polluting aquatic ecosystems. This study…
Valmori A, Manzi C, von Hippel C · 2026 · Preprint
As workplaces become increasingly diverse in age and gender, understanding how discrimination affects employees' experiences and decisions to remain with their organisations is essential. This study examined how perceived ageism and sexism…
Gomez Isaza D, Rodgers E · 2026 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Daily temperature fluctuations are a ubiquitous feature of natural environments, yet our understanding of how ectotherms respond to thermal variability remains incomplete. Previous frameworks have predicted that exposure to variable…
Margiotta ER, Kennedy D, Hawkins LR et al. · 2026 · Global change biology
Plant functional traits moderate ecosystem responses to climate and exchanges of water and carbon between the land surface and the atmosphere. However, the extent to which diversity in functional traits influences global carbon and…
Zeng X, Zeng C, Zhou Y et al. · 2026 · Conservation biology : the journal of the Society for Conservation Biology
Multiuse marine protected areas (MMPAs) with varying levels of protection in different zones are increasingly being adopted to balance conservation and socioeconomic goals. However, the effect of these zone-based strategies on fish…
Utonga D, Tundui CS, Mkuna E · 2026 · Preprint
Abstract This study analysed the determinants of the levels of digital technology adoption (DTA) among SMEs in the fruit juice processing industry in Tanzania. Anchored in the Technology Acceptance Model (TAM) and the…
Moreira MM, Dias LPB, Guzman YC et al. · 2026 · Journal of evolutionary biology
Intracellular endosymbionts such as Wolbachia are generally thought to persist in host populations by inducing reproductive phenotypes that enhance maternal transmission, often at the expense of male hosts. Here, we examined the fitness…
Mukherjee K, Ren D, Moritz D et al. · 2026 · IEEE transactions on visualization and computer graphics
Multimodal vision-language models (VLMs) continue to achieve ever-improving scores on chart understanding benchmarks. Yet, we find that this progress does not fully capture the breadth of visual reasoning capabilities essential for…
Ramesh N, Klaiber P · 2026 · Acta psychologica
Academic self-efficacy is theorised to foster favourable academic outcomes. While academic self-efficacy is believed to have a reciprocal relationship with academic mastery experiences, longitudinal naturalistic investigations are…
Costan CA, Godsoe W, Bufford JL et al. · 2024 · Plant Ecol.
It has long been hypothesised that introduced species can evolve to become better competitors, which in turn will enable some of them to become invasive. The evolution of increased competitive ability hypothesis (EICA) gives a possible…
D'Andrea W, Freed S, DePierro J et al. · 2024 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)
The startle eyeblink reflex is thought to function as a means of orienting to salient stimuli, and, by proxy, sensitivity to threat cues. The absence or attenuation of this reflex may thus suggest disengagement from one's environment,…