Negative / Null Result ReportOpen accessMedicine
Fousekis E, Arhakis A, Arapostathis K et al. · 2026 · Biomimetics (Basel, Switzerland)
The aim of the study was to evaluate the immediate and aged shear bond strength (SBS) of a dual-cured and a light-cured universal adhesive to primary and permanent dentin. Twenty caries-free primary molars and twenty permanent third molars…
View details →DOI: 10.3390/biomimetics11050358 Negative / Null Result ReportOpen accessMedicine
Makrantonakis A, Mantzoros I, Ioannidis O et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Intraperitoneal onlay mesh (IPOM) reduces ventral/incisional hernia recurrence but raises concern for adhesions and infection, particularly when the operative field is not strictly clean. We aimed to determine…
View details →DOI: 10.3390/medicina62050803 Negative / Null Result ReportOpen accessMedicine
Seetharama DB, Prasad K, Prakash VR et al. · 2026 · Cureus
Introduction Acute coronary syndrome (ACS) is a major manifestation of coronary heart disease and is associated with significant morbidity and mortality. Inflammatory and thrombotic mechanisms play an important role in its pathogenesis.…
View details →DOI: 10.7759/cureus.105558 Negative / Null Result ReportMedicine
Eminsoy Avcı AT, Yavuz B, Karakaya B et al. · 2026 · BMC oral health
Background This randomized clinical trial aimed to compare postoperative pain (PP) and analgesic consumption following single-visit root canal treatment using two calcium silicate-based sealers (BioMTA + and Well-Root PT) and one epoxy…
View details →DOI: 10.1186/s12903-026-08525-x Negative / Null Result ReportOpen accessMedicine
Zhao FY, Yue LP, Ho YS et al. · 2026 · Nature and science of sleep
Background and aims Insomnia during pregnancy is potentially associated with adverse outcomes, including gestational diabetes mellitus, pre-eclampsia, cesarean delivery, preterm birth, and depression. This study aimed to synthesize…
View details →DOI: 10.2147/nss.s607896 Negative / Null Result Report
Onaghise J, A DK · 2026 · Preprint
Abstract Background Rural working-age adults in West Africa face a compounding burden of rising non-communicable disease prevalence, specifically hypertension and diabetes, and severe structural barriers to accessing formal healthcare.…
View details →DOI: 10.21203/rs.3.rs-10096350/v1 Negative / Null Result ReportMedicine
Champion KA, AlDosari M · 2026 · Journal of dental education
Purpose Few evidence-based tools exist to support holistic review in dental school admissions. The Holistic Admissions Assessment Rubric (HAAR) was developed to score applicant data from the Associated American Dental Schools Application…
View details →DOI: 10.1002/jdd.70294 Negative / Null Result ReportMedicine
Zhou Y, Qin S, Ma Y · 2026 · Clinical and experimental hypertension (New York, N.Y. : 1993)
Background Essential hypertension (EH) remains a leading modifiable risk factor for cardiovascular morbidity and mortality worldwide. Electroacupuncture (EA), combining traditional acupuncture with pulsed electrical stimulation at specific…
View details →DOI: 10.1080/10641963.2026.2685125 Negative / Null Result ReportOpen accessMedicine
Sun Y, Yang X, Zhu Q et al. · 2026 · Drug design, development and therapy
Autoimmune thyroiditis (AIT) is a chronic immune-mediated thyroid disorder characterized by lymphocytic infiltration, follicular epithelial injury, autoantibody production, and variable progression to thyroid dysfunction. Because current…
View details →DOI: 10.2147/dddt.s614133 Negative / Null Result ReportMedicine
Aubret A, Triesch J · 2026 · Developmental science
There is strong and diverse evidence for mental rotation (MR) abilities in adults. However, current evidence for MR in children rests on just a few behavioral paradigms adapted from the adult literature. Here, we leverage recent…
View details →DOI: 10.1111/desc.70240 Negative / Null Result ReportMedicine
Yu J, Eyles JP, Moreti Cabral Silveira A et al. · 2026 · BMC health services research
Background Evidence based medicine is a critical cornerstone in contemporary medicine, yet uptake and adoption of evidence remain suboptimal. This is prominent in many fields of healthcare, including musculoskeletal health and surgery.…
View details →DOI: 10.1186/s12913-026-14843-1 Negative / Null Result Report
Parisien C, Ho-El Abidi N, Khalaf E et al. · 2026 · Preprint
Addiction is a chronic, relapsing disorder comprising three stages: binge, withdrawal, and preoccupation. Preclinical evidence suggests that the habenula, a small epithalamic region, is involved across these stages and may contribute to…
View details →DOI: 10.31234/osf.io/snyvc_v1 Negative / Null Result ReportMedicine
Scurich N, Albright TD · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Proficiency testing is widely used to assess expertise in medicine, engineering, and other high-stakes fields. In forensic science, such tests are often cited in court as evidence that pattern-comparison methods are accurate and reliable.…
View details →DOI: 10.1073/pnas.2528192123 Negative / Null Result Report
Mahon P, Körtner G · 2026 · Preprint
Abstract Measuring the effectiveness of management programmes for alien invasive predators can be difficult not least because the densities of these species are often hard to estimate. We estimated the proportion of nights ( incursion rate…
View details →DOI: 10.21203/rs.3.rs-9608274/v1 Negative / Null Result ReportMedicine
Stewart JJ, Allen BS, Polutchko SK et al. · 2026 · Journal of experimental botany
Refilling of xylem embolism during recovery from drought has been studied for decades, although the legitimacy of supporting evidence has been debated in recent years due to potentially widespread methodological artifacts associated with…
View details →DOI: 10.1093/jxb/erag294 Negative / Null Result ReportOpen accessMedicine
van der Steege AE, Humuza J, Shyirambere C et al. · 2026 · BMJ global health
Introduction The WHO Model Lists of Essential Medicines (MLEM and MLEMc) guide national medicine selection, particularly in low-income and lower middle-income countries (LMICs). Concerns exist about the adequacy and transferability of…
View details →DOI: 10.1136/bmjgh-2025-022533 Negative / Null Result ReportMedicine
Ganguly A, Bhowmik S, Hajra A · 2026 · Therapeutic hypothermia and temperature management
Shivering is a common complication of targeted temperature management (TTM), which could undermine its neuroprotective benefits by increasing cerebral oxygen consumption and metabolic demand. Buspirone, a 5-HT1A receptor partial agonist,…
View details →DOI: 10.1177/21537658261464859 Negative / Null Result ReportMedicine
Simone J, Cooke C, Lee S et al. · 2026 · Sexually transmitted infections
Congenital syphilis (CS) has been rapidly re-emerging as a public health crisis across North America. The present standard of care treatment for CS involves a 10-day hospitalisation for intravenous penicillin G, which is costly for…
View details →DOI: 10.1136/sextrans-2025-056692 Negative / Null Result ReportMedicine
Jin X, Shen T, Wang Y et al. · 2026 · JBI evidence implementation
Introduction Auditory hallucinations, persistent and distressing symptoms in patients with schizophrenia, are often poorly controlled by antipsychotics. Structured non-pharmacological interventions remain limited in routine clinical…
View details →DOI: 10.1097/xeb.0000000000000595 Negative / Null Result ReportMedicine
Black CFD, Phillips C, Sanders IA et al. · 2026 · Child maltreatment
It is unclear whether research has generated causal evidence about the impact of mandatory reporting (MR) policies on reporting outcomes. This scoping review applied concepts from the NIH Stage Model to map and organize five decades of…
View details →DOI: 10.1177/10775595261448548 Negative / Null Result ReportMedicine
Gao Y, Liu M, Li L et al. · 2026 · The Cochrane database of systematic reviews
Background Triple-negative breast cancer (TNBC), an aggressive subtype lacking oestrogen and progesterone receptors and amplification of HER2 receptors, accounts for 12% to 17% of breast cancers. Adjuvant and neoadjuvant chemotherapy…
View details →DOI: 10.1002/14651858.cd015072.pub3 Negative / Null Result ReportMedicine
Brock AS · 2026 · American journal of speech-language pathology
Purpose The objective of this review article is to examine and describe the literature on training speech-language pathology students on the principles of evidence-based practice (EBP). Method A scoping literature review was undertaken in…
View details →DOI: 10.1044/2026_ajslp-25-00227 Negative / Null Result ReportOpen accessMedicine
Yao S, Xu L · 2026 · Frontiers in medicine
Background Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory breast disease characterized by a prolonged clinical course with recurrent episodes, and the optimal treatment remains controversial. Multiple systematic…
View details →DOI: 10.3389/fmed.2026.1852206 Negative / Null Result ReportOpen accessMedicine
Gazit N, Ben-Gal G, Eliashar R · 2026 · JMIR medical education
Background Assessment of technical aptitude, cognitive abilities, and personality characteristics is important in selecting candidates for surgical training. Currently, the selection of surgical training candidates does not systematically…
View details →DOI: 10.2196/82515 Negative / Null Result ReportOpen accessMedicine
Du Y, Xu Z, Wen T et al. · 2026 · Diabetes, metabolic syndrome and obesity : targets and therapy
Purpose The care of diabetic foot ulcers (DFU) continues to be a notable clinical challenge. The efficacy and safety of stem cell therapies versus conventional treatments for DFU are debated. Cross-sectional analyses of meta-analyses…
View details →DOI: 10.2147/dmso.s593437 Negative / Null Result ReportOpen accessMedicine
Zhang Y, Wu Z · 2026 · Frontiers in public health
Background Digital technologies in oncology require patients and health workers to possess adequate electronic health literacy (eHealth literacy). Yet, the extent to which this literacy influences cancer-specific insights, ranging from…
View details →DOI: 10.3389/fpubh.2026.1781759 Negative / Null Result ReportMedicine
Hou YN, Gubili J, Mao JJ · 2026 · Seminars in radiation oncology
Studies show that patients with cancer use herbal products more often than the general population. Lowering the risk of disease recurrence, symptom control, and improving quality of life are often the reasons cited for such use. However, a…
View details →DOI: 10.1016/j.semradonc.2026.151035 Negative / Null Result ReportOpen accessMedicine
Kyei EF, Kyei GK, Forson MM et al. · 2026 · Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing
Aim To examine nurse practitioner opioid prescribing authority across three countries, analyzing safety outcomes, workforce distribution patterns, access equity, and service to vulnerable populations using integrated nursing policy and…
View details →DOI: 10.1111/jnu.70109 Negative / Null Result ReportOpen accessMedicine
Tafuri MG, Monda V, La Marra M et al. · 2026 · Nutrients
Background/Objectives: Sport participation and nutrition are increasingly recognized as key determinants of cognitive function and academic achievement in student populations. However, the biological mechanisms underpinning these…
View details →DOI: 10.3390/nu18111651 Negative / Null Result ReportMedicine
Leahy TP, Keenan C, Robertshaw E et al. · 2026 · Value in health regional issues
Objectives Growing reliance on single-arm trials (SATs) is driving increased real-world external control arm (RW-ECA) use in health technology assessment submissions. However, concerns over residual confounding and unmeasured bias often…
View details →DOI: 10.1016/j.vhri.2026.101651