A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19893 results in Negative / Null Result Report · page 543 of 664
Wöhner S, Jescheniak JD · 2025 · Preprint
The production of a word is delayed by the recent production of one or more semantically related words. This phenomenon, known as semantic interference, has been observed in picture naming tasks involving either large sets of pictures…
Starr M, Frampton A, Mika A et al. · 2026 · Preprint
Background: : Peri-anaesthetic hypothermia is a well-documented complication of general anaesthesia and is associated with prolonged recovery, impaired wound healing, and delayed coagulation. Fluid warmers can be used to mitigate heat…
Richard NA, Claydon VE, Koehle MS et al. · 2026 · Medicine and science in sports and exercise
Introduction Female athletes, or those in arduous occupations, lack objective guidance on effective and safe rigorous training postpartum. We examined the effectiveness and tolerability of early postpartum sprint interval training (SIT) in…
Cuttance EL, Mason WA, Jamieson P et al. · 2026 · New Zealand veterinary journal
Aims To evaluate, in a sample of cows on a New Zealand dairy farm, whether different methods of oral supplementation with zinc were effective in raising serum Zn concentrations ≥ 18 μmol/L, the target threshold for protection from facial…
Charles F, Reside A, Moss P et al. · 2026 · Preprint
In fire-prone regions globally, evolution of plant traits that confer resilience to historical fire regimes is widespread. However, many common plant species are currently declining due to a mismatch between historical and contemporary…
Çetin DD, Ölmez Ş, Sarıtaş B et al. · 2026 · Preprint
Abstract Background Percutaneous endoscopic gastrostomy (PEG) is the preferred method for long-term enteral nutritional support in patients unable to maintain adequate oral intake. PEG candidates often present with multiple comorbidities…
Chen W, Zhou Y, Wang M et al. · 2026 · Acta psychologica
This study aimed to explore the impact of calligraphy training on the emotional well-being of college students，as well as the mediating roles of state mindfulness and rumination in this relationship, using a cross-sectional design (N =…
Wang Y, Song Z, Guo Q et al. · 2026 · Environmental science & technology
Mounting evidence confirms that microplastics (MPs) pose ecological risks. Despite the environmental relevance of aged MPs under warming, little is known about their particle versus leachate toxicity. Here, we mechanistically quantify…
Azaad S, Echterhoff G · 2025 · Preprint
Many experiments in psychology involve deceiving participants about aspects of the study. Researchers who employ deception sometimes administer post-experiment suspicion probes and exclude participants from analysis if their responses…
Lerche CM, Granborg JR, Al-Chaer RN et al. · 2025 · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Glyphosate (GLY) is the most widely used pesticide in the world. Agricultural workers are exposed to GLY via ingestion and skin contact. GLY may generate epigenetic changes that might be carcinogenic. However, whether GLY is carcinogenic…
Suksathien Y, Suarjui J, Tippimanchai T et al. · 2026 · International orthopaedics
Purpose Intraoperative calcar fracture (IOCF) can compromise initial stability, leading to stem subsidence and instability. We aimed to compare 2-year complications and revision rates between patients who sustained IOCF and matched…
Chesney KM, McAbee JH, Balu A et al. · 2026 · Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Purpose Tethered cord release (TCR) is typically well tolerated in children, but cerebrospinal fluid (CSF) leaks can occur postoperatively, with rates as high as 33%. The aim of this study was to determine perioperative risk factors…
Gorsagun S, Pruksanusak N, Geater AF · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Objective To compare pregnancy outcomes between early and standard treatment of gestational diabetes mellitus (GDM) diagnosed using the Carpenter-Coustan criteria and to assess the impact of applying the International Association of…
Dai H, Wang Y, Shan F et al. · 2026 · BMC gastroenterology
Background Neoadjuvant chemotherapy (NAC) and neoadjuvant chemoradiotherapy (nCRT) are increasingly used to treat adenocarcinoma of the esophagogastric junction (AEG). However, there is insufficient clinical evidence to compare surgical…
Sato M, Torii K, Hiramatsu Y et al. · 2026 · Surgical endoscopy
Background Safe establishment of pneumoperitoneum is essential in laparoscopic surgery because most access-related injuries occur during peritoneal entry. In Veress needle procedures, this step is performed blindly, and conventional…
Muto T, Machida S, Imaizumi S et al. · 2026 · Journal of ophthalmology
Purpose To determine the prevalence and clinical characteristics of retinal artery occlusion (RAO), including branch RAO (BRAO) and central RAO (CRAO), among new patients before and after the declaration of a state of emergency due to…
Maschoreck LG, Stokholm L, Pedersen FN et al. · 2026 · Acta ophthalmologica
Purpose Diabetic retinopathy (DR) is a frequent long-term complication of diabetes. While hemodynamic changes are known risk factors for DR, the effect of coronary artery bypass grafting (CABG) on the development of DR is poorly…
Elhoweris AE, Sullivan M, Norton W et al. · 2026 · Transplantation proceedings
Background Urinary tract infections (UTIs) are the most common infection following kidney transplantation. However, the natural history of UTIs is incompletely understood, as is the impact of UTIs on patient outcomes. Methods A…
Wang N, Xu T, Li H et al. · 2026 · International journal of radiation oncology, biology, physics
Purpose To characterize the long-term endoscopic natural history of chronic radiation proctitis (CRP) and identify predictors of severe lesions in patients with locally advanced rectal cancer from the STELLAR study (NCT02533271) . Methods…
Berends E, Guimbal S, Zhang X et al. · 2026 · Preprint
Background Methylglyoxal (MGO), a highly reactive by-product of glycolysis, has been associated with cognitive decline and Alzheimer’s disease, though the mechanistic role of MGO remains unclear. Moreover, conflicting findings exist…
Sano Y, Yagi N, Ito Y et al. · 2026 · Digestive diseases and sciences
Background and aims The role of 5-aminosalicylates (5-ASA) in maintaining remission in patients with ulcerative colitis (UC) receiving advanced therapy remains controversial. This study evaluated the safety and feasibility of 5-ASA…
Smith DC, Gemkow JW, Shiferaw BA et al. · 2026 · Journal of midwifery & women's health
Introduction Use of labor induction has increased rapidly for medical and nonmedical reasons, raising questions about its impact on cesarean birth rates. With growing incidence of elective induction of labor (IOL) at 39 weeks, uncertainty…
Koskinen JP, Harju M, Välimäki J · 2026 · Acta ophthalmologica
Purpose To evaluate changes in corneal tomography, pachymetry and endothelial cell density (ECD) following Paul Glaucoma Implant (PGI) surgery. Methods Seventy-three patients were prospectively examined. Repeated measures anova was used to…
Wang Q, Kimura Y, Oba J et al. · 2026 · European journal of pediatrics
Routine echocardiography at one month after diagnosis is the current standard for screening coronary artery abnormalities (CAA), a major complication of Kawasaki disease. The study aimed to develop and validate models to predict CAA and…
Kralj-Fišer S, Čelik T, Fišer C et al. · 2026 · Preprint
Abstract Fecundity selection is widely invoked to explain female-biased sexual size-dimorphism (SSD), yet tests based on lifetime reproductive output remain scarce. We quantified lifetime fecundity and age-dependent reproduction in the…
Jenkins TL, Darden K, Pourdeyhimi B et al. · 2026 · Journal of biomechanics
Synthetic polymer scaffolds with aligned fibers permit engineered tendon development and the formation of an aligned, collagen rich matrix. However, many tissue engineered constructs cannot withstand physiologically relevant loads. Both…
Mohammadi S, Cunnane ME, Juliano AF et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Four-dimensional CT (4D-CT) is a key imaging modality for preoperative localization of parathyroid adenomas in primary hyperparathyroidism. Ultrasound (US) is frequently added with the assumption that it enhances…
Santoro SL, Alvarado C, Tseng SY et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
Objective In 2022, the U.S. Supreme Court decision on Dobbs v. Jackson Women's Health Organization changed abortion access. We evaluated birth rates of Down syndrome (DS) before and after the Dobbs decision hypothesizing similarity to…
Ukita K, Egami Y, Sugino A et al. · 2026 · Clinical research in cardiology : official journal of the German Cardiac Society
Background Several studies have investigated the efficacy of additional left atrial (LA) roof ablation to pulmonary vein isolation (PVI) using cryoballoon for persistent atrial fibrillation (AF). However, the evidence from randomized…
Aragón-Sánchez J, Víquez-Molina G, Aragón-Hernández J et al. · 2026 · Advances in skin & wound care
Objective The authors hypothesized that prior antibiotic treatment does not reduce culture positivity and that empirical antibiotic therapy in culture-negative cases does not increase the risk of amputation or recurrence in…