A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19893 results in Negative / Null Result Report · page 541 of 664
Aney P, Zeng S, Kensinger EA et al. · 2025 · Neuropsychologia
Background Human memory tends to bias negative over neutral information. Recent evidence suggests that this bias may be due to a categorical effect of emotionally salient information, which diminishes when negative information is less…
Chida K, Oshi M, Roy AM et al. · 2024 · Breast cancer research and treatment
Purpose While comprehensive research exists on the mutation of the DNA repair gene BRCA1, limited information is available regarding the clinical significance of BRCA1 gene expression. Given that cancer cell proliferation is aggrevated by…
Troha R, Lee SLT, Anam M et al. · 2025 · Frontiers in systems neuroscience
The hippocampus plays a prominent role in spatial navigation and memory. However, differences exist along the hippocampus longitudinal axis in function and connectivity. The current study focuses on the dorsal and intermediate subregions…
Beltrami FG, Mullarkey J, Spengler CM · 2026 · Frontiers in sports and active living
Introduction Whole-body exercise can attenuate postprandial glucose (PPG) excursions, one of the three main components in glucose control. Respiratory muscle endurance exercises (RMEE) based on resisted hyperpnea could offer an alternative…
Randolph C, Needlman R, Hutchinson E · 2024 · American journal of community psychology
Political engagement (PE) is associated with a sense of empowerment. PE by parents affects children's lives. This study explored parents' attitudes about inclusion of political engagement discussion in well-child care. Because voting is an…
Kambanis PE, Graver H, Palmer LP et al. · 2025 · The International journal of eating disorders
Objective Little is known about the timing of behavioral versus cognitive change in 10-session cognitive-behavioral therapy for non-underweight eating disorders (CBT-T). We aimed to: (a) evaluate the magnitude of behavioral and cognitive…
Paulussen KJM, Hayden CMT, Griffin T et al. · 2025 · Matrix biology plus
Following resistance exercise, systemic changes foster improved functionality of tendons and ligaments. Post-exercise, muscle tissue releases exosomes that are thought to facilitate inter-tissue communication. To determine the potential…
Carney BC, Travis TE, Keyloun JW et al. · 2024 · Burns : journal of the International Society for Burn Injuries
Dyschromic hypertrophic scar (HTS) is a common sequelae of burn injury, however, its mechanism has not been elucidated. This work is a histological study of these scars with a focus on rete ridges. Rete ridges are important for normal skin…
Becker LF, Sallandt GM, Rosolowsky E et al. · 2025 · Scientific reports
Response inhibition can be explained within the theory of event coding. Event file binding and reconfiguration have previously been studied in relation to various neurotransmitters. We aimed to activate the noradrenergic system through…
Shahsavari Pour A, Hosseini A, Ghomashi I et al. · 2026 · The archives of bone and joint surgery
Objectives This study aimed to compare the clinical outcomes of trans-tibial pullout repair of the medial meniscus posterior root using the lateral tibial tunnel versus the conventional medial tibial tunnel. Methods In this prospective…
Alhamdi H, Deroche E, Shatrov J et al. · 2025 · SICOT-J
Introduction The understanding of the influence of posterior tibial slope (PTS) on knee kinematics has increased. However, the PTS influence on clinical outcomes remains unclear. The study aimed to evaluate whether a significant change…
Lo MM, Black MN, McGlory C et al. · 2026 · Physiological reports
Mitochondrial subcellular area influences function. Muscle disuse reduces mitochondrial content; however, its effect on mitochondrial subcellular location is unclear. Omega-3 fatty acid (n-3) attenuates declines in muscle mass and…
Laird‐Hopkins BC, Ashe‐Jepson E, Basset Y et al. · 2023 · Global Change Biology
Climate change is a major threat to species worldwide, yet it remains uncertain whether tropical or temperate species are more vulnerable to changing temperatures. To further our understanding of this, we used a standardised field protocol…
Vallesi V, Galléa C, Sritharan J et al. · 2025 · Brain communications
Functional paralysis (FP), a subtype of functional neurological disorder (FND), is characterized by symptoms of paralysis without clinically evident damage to the nervous system. Previous research has reported impaired inhibitory control…
Erickson MG, Zanton GI, Wattiaux MA · 2023 · Journal of dairy science
Limited research has examined the interaction between dietary crude protein (CP) level and CP feeding pattern. We tested CP level (low protein [LP], 13.8%; high protein [HP], 15.5% CP, dry matter [DM] basis) and CP feeding pattern (OF =…
Speed LJ, de Valk J, Croijmans I et al. · 2023 · Cognitive science
Odor and color are strongly associated. Numerous studies demonstrate consistent odor-color associations, as well as effects of color on odor perception and language. Yet, we know little about how these associations arise. Here, we test…
Goldway N, Markovits T, Fine N et al. · 2026 · Biological psychiatry global open science
Background Dissociation, an altered state of consciousness in which individuals feel detached from their body, environment, and sense of self, is a common feature of posttraumatic stress disorder (PTSD). Despite its significance, the…
Lande NM, Ask TF, Sætren SS et al. · 2023 · Preprint
Background: Self-efficacy, the belief in one’s ability and capacity to organize and execute actions required to achieve desired results, is associated with adolescent academic achievement and reduced risk for psychopathology. Adolescent…
Renwick JRM, Preobrazenski N, Giudice MD et al. · 2024 · International journal of exercise science
The purpose of the current study was to test the hypothesis that individual response classification for surrogate markers of cardiorespiratory fitness (CRF) will agree with response classification for VO 2peak . Surrogate markers of CRF…
Fujii N, Takahashi K, Kawama R et al. · 2026 · PloS one
Higher stiffness of the medial gastrocnemius (MG) has been reported to be associated with faster race time in 100-m sprint running. However, the association of muscle stiffness with spatiotemporal variables (i.e., step frequency, step…
Bastiani O, Dardani C, Burrows K et al. · 2024 · Preprint
Observational studies report prospective associations of neurodevelopmental and psychiatric traits with paediatric incontinence and constipation, but unmeasured and residual confounding may limit observational measures. Here, we use a…
· 2022 · Current developments in nutrition
Abstract Objectives To examine and compare reported food and nutrient intake in men and women who differ in cognitive restraint (CR) and disinhibition (D) scores. We hypothesize that average intake of sodium, total sugar, saturated fat,…
Pupo MR, Diepersloot EC, Wenzel MPR et al. · 2026 · JDS communications
Feeding spoiled silage with high yeast activity is commonly related to impaired lactation performance by dairy cows. However, rehydrated corn grain silage (RCGS) may be more prone to yeast proliferation and be greatly affected by high…
Yao Y, Liu SS, Jin L et al. · 2025 · Clinical and experimental dental research
Objectives Anterior disc displacement with reduction (ADDWR) and without reduction (ADDWOR) are two common clinical types of temporomandibular disorders. This study compared the levels of anxiety, depression, somatization, and jaw function…
Kjeldsted E, Ammitzbøll G, Lænkholm AV et al. · 2025 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose Preclinical studies have indicated that physical exercise may enhance chemotherapy efficacy. However, clinical trials are needed to investigate these findings. We hypothesized that an exercise program during neoadjuvant…
Gautier R, Latinus M, Briend F · 2025 · Psychophysiology
The heartbeat evoked potential (HEP) is a potential marker of cardiac signal integration at the cerebral level, obtained by averaging epochs time-locked to the ECG R-peaks. The HEP is modulated across different experimental conditions with…
Itzhaky L, Chubarov E, Keilp JG et al. · 2023 · Psychiatry research
An increase in suicide rates during adolescence has made it the second leading cause of death for this age group. While potential deficits in cognitive flexibility have been thought to contribute to suicidality, this factor has been…
Marek MJ, Wolke D, Sorg C et al. · 2026 · NeuroImage. Clinical
This study investigates the long-term effects of very preterm (VPT) birth (<32 weeks of gestation) on cognitive control and structural brain network topology. Data were obtained from 61 very VPT and 79 full term (FT) individuals aged 26…
Grave J, Cordeiro S, De Sá Teixeira NA et al. · 2022 · Preprint
Schizotypy, a personality structure that resembles schizophrenia symptoms, is often associated with abnormal facial emotion perception. Based on the prevailing sense of threat in psychotic experiences, and the immediate perceptual history…
Guerreiro M, Borges F, Santos C et al. · 2023 · Preprint
Abstract Climate change is expected to produce major effects across marine life, and cephalopods seem to benefit from these effects. Of these animals, squids exhibit the greatest levels of biomass and of a substantial importance for human…