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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19893 results in Negative / Null Result Report · page 538 of 664

Negative / Null Result ReportOpen accessMedicine

Psychotic-Like Experiences and White Matter Microstructure: A Fixel-Based Analysis Approach With Robust Replication Across Two Cohorts.

Goodwin I, Larsen KM, Sangchooli A et al. · 2025 · Human brain mapping

Structural deficits in white matter fibre have been linked to psychosis. However, it remains unclear whether these aberrations are present in individuals that experience non-clinical psychotic-like experiences, predating illness onset.…

View details →DOI: 10.1002/hbm.70414
Negative / Null Result ReportMedicine

Outcomes and performance following posteromedial elbow débridement in Major League Baseball players.

Wollenman CC, Davis PJ, Lane GC et al. · 2024 · Journal of shoulder and elbow surgery

Background Overhead athletes are particularly susceptible to elbow valgus extension overload syndrome and development of pathologic changes in the posteromedial elbow. Though arthroscopic débridement/osteophyte resection is frequently…

View details →DOI: 10.1016/j.jse.2024.05.035
Negative / Null Result ReportMedicine

Effects of Naltrexone on Sleep Quality and Periodic Breathing at High Altitude.

Foster K, Anholm JD, Foster G et al. · 2025 · High altitude medicine & biology

Foster, Katharine, James D. Anholm, Gary Foster, Suman Thapamagar, and Prajan Subedi. Effects of naltrexone on sleep quality and periodic breathing at high altitude. High Alt Med Biol. 26:13-19, 2025. Objective: This study examined the…

View details →DOI: 10.1089/ham.2024.0023
Negative / Null Result ReportOpen accessMedicine

Breath-Holding Maneuvers and Airway Closure in Healthy Adults and Parkinson's Disease: Effects of Maneuver Type, Health Status, and Vocal Fold Bowing.

Curtis JA, Beam AB, Nam J et al. · 2025 · Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)

Introduction Breath-holding maneuvers are frequently used to improve airway closure and swallowing safety in people with dysphagia. While their effects on airway closure have been studied in healthy adults, little is known about their…

View details →DOI: 10.1159/000550088
Negative / Null Result ReportOpen accessMedicine

Influence of Immobilization, Stretching, and Activity on the Morphological Properties of Spastic Gastrocnemius Muscles.

Habersack A, Kruse A, Guggenberger B et al. · 2026 · Children (Basel, Switzerland)

Background/Objectives: Children with cerebral palsy (CP) often develop altered muscle architecture and calf muscle contractures. Orthotic immobilization aims to provide prolonged stretch to lengthen the muscle belly and muscle-tendon unit…

View details →DOI: 10.3390/children13030414
Negative / Null Result ReportMedicine

Effects of Time of Arrival on Trauma Patient Outcomes.

LaRosa SK, Stone XA, Fenninger AA et al. · 2024 · The American surgeon

Background Arriving during "off hours" to the hospital can put patients at greater risk of complications or mortality given lesser staff. Our goal was to investigate this in trauma patients with an Injury Severity Score (ISS) of >15. We…

View details →DOI: 10.1177/00031348241248694
Negative / Null Result ReportMedicine

Motor and Cognitive Sequence Tasks Exhibit Different Ramping Patterns in Parietal and Prefrontal Cortices.

Doyle H, Yewbrey R, Kornysheva K et al. · 2025 · Journal of cognitive neuroscience

Humans complete different types of sequences as a part of everyday life. These sequences can be divided into two important categories: those that are abstract, in which the steps unfold according to a rule at super-second to minute time…

View details →DOI: 10.1162/jocn_a_02349
Negative / Null Result ReportMedicine

Climatic resilience: Marine heatwaves do not influence the variations of green crab (Carcinus maenas) megalopae supply patterns to a Western Iberian estuary.

Monteiro M, Azeiteiro UM, Queiroga H · 2024 · Marine environmental research

Extreme climatic events like marine heatwaves (MHWs) are becoming more frequent, intense, and longer lasting all around the world. The consequences of these anomalously warm periods are devastating for marine ecosystems. Still, little is…

View details →DOI: 10.1016/j.marenvres.2024.106567
Negative / Null Result ReportOpen accessMedicine

Flexible Goal Adjustment Predicts Well-Being Before and After Retirement.

Viegas LM, Bermeitinger C, Greve W · 2026 · Journal of aging research

Background and objectives Retirement represents a critical life change and is accompanied by the blocking of professional goals. We assume that the individual capability to adapt goals to changed conditions has a palliative effect on…

View details →DOI: 10.1155/jare/2950011
Negative / Null Result ReportMedicine

An acute social stressor decreases reinforcing value of both high and low energy-dense food in college students in a randomized controlled trial.

McKay NJ, Horvatits EJ, Jean M et al. · 2024 · Physiology & behavior

It is well known that a large portion of the population elevates their intake of high energy-dense foods during times of stress; however, it is understudied whether stress affects the reinforcing value of a food reward. Further knowledge…

View details →DOI: 10.1016/j.physbeh.2024.114531
Negative / Null Result ReportOpen accessMedicine

Oxytocin administration during labor does not affect maternal serum oxytocin levels, early postpartum breastfeeding attitude and maternal attachment.

Özdemir M, Çeber Turfan E, Keskin HL · 2025 · PloS one

The goal was to investigate the effects of synthetic oxytocin administration during labor on maternal and neonatal serum oxytocin levels, early breastfeeding attitudes, and postpartum maternal attachment immediately after birth. This…

View details →DOI: 10.1371/journal.pone.0337762
Negative / Null Result ReportOpen accessMedicine

Contribution of sympathetic nervous system activation to endothelial ischemia reperfusion injury in healthy adults.

Rosenberg AJ, Young BE, Fernandez A et al. · 2025 · Physiological reports

Ischemia-reperfusion injury (IRI) describes the phenomenon through which the restoration of blood flow following prolonged ischemia exacerbates tissue damage during reperfusion. IRI can be modeled by inducing 20-min arm ischemia followed…

View details →DOI: 10.14814/phy2.70502
Negative / Null Result ReportMedicine

Greater Emotional and Psychological Well-being Are Associated With Reduced Employee Self-report Illness-Related Absenteeism: A Multi-Industry, Cross-sectional Study Conducted During COVID-19 Pandemic.

Fannin A, Hooley C, Nelson EJ · 2024 · Journal of occupational and environmental medicine

Objective The purpose of this study is to determine the relationship that emotional, psychological, and social well-being has with self-reported illness-related absenteeism. Methods This study examines the relationship between three…

View details →DOI: 10.1097/jom.0000000000003042
Negative / Null Result ReportOpen accessMedicine

A conditional process analysis of general self-esteem in student-athletes in lower secondary sport schools.

Gjesdal S, Kristensen JÅ, Saarinen M et al. · 2026 · Frontiers in psychology

Objective Specialised sport schools at the lower secondary level aim to support the holistic development of young athletes. Consequently, understanding how to influence student-athletes' self-perceptions both inside and outside of the…

View details →DOI: 10.3389/fpsyg.2026.1771557
Negative / Null Result ReportOpen accessMedicine

Effects of mindful breathing meditation on stereotype expression in two randomized controlled double-blinded trials.

Vieth E, von Stockhausen L · 2026 · PloS one

Models of stereotypes and discrimination propose the involvement of attentional control and executive functioning in successfully suppressing discriminatory behavior. A practice that has been shown to improve cognitive control, potentially…

View details →DOI: 10.1371/journal.pone.0347871
Negative / Null Result ReportOpen accessMedicine

Impact of Blood Group on Contralateral Suppression of Otoacoustic Emissions, Speech Perception in Noise, and Binaural Integration.

Ponnana S A P, Tauro JP, S NP et al. · 2026 · International archives of otorhinolaryngology

Introduction Understanding the relationship between blood groups (A, B, AB, and O) and auditory functioning can provide valuable insights into individual differences in hearing ability and potential risks for hearing loss. Objective To…

View details →DOI: 10.1055/s-0046-1819712
Negative / Null Result ReportOpen accessMedicine

Cardiac Biomarkers in Patients With Asymptomatic Severe Aortic Stenosis: Analysis From the EARLY TAVR Trial.

Lindman BR, Pibarot P, Schwartz A et al. · 2025 · Circulation

Background The EARLY TAVR trial (Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis) demonstrated that early transcatheter aortic valve replacement (TAVR) intervention was superior to clinical…

View details →DOI: 10.1161/circulationaha.125.074425
Negative / Null Result ReportMedicine

Neurocognitive Profile of Avoidant/Restrictive Food Intake Disorder: Cognitive Flexibility, Delay Discounting, and Detail Orientation.

McPherson IK, Dalton AG, Armstrong K et al. · 2026 · The International journal of eating disorders

Objective Neurocognitive deficits are well-documented across psychiatric disorders and may indicate novel treatment targets. However, empirical data on the neurocognitive profile of avoidant/restrictive food intake disorder (ARFID) are…

View details →DOI: 10.1002/eat.70077
Negative / Null Result ReportMedicine

A shift to a standard diet after exposure to a high-fat, high-sucrose diet from gestation to weaning restores brain metabolism and behavioral flexibility in adult rats.

Sal-Sarria S, López-Taboada I, González-Pardo H et al. · 2024 · Behavioural brain research

Prolonged consumption of diets high in saturated fat and sugar has been related to obesity and overweight, which in turn are linked to cognitive impairment in both humans and rodents. This has become a current issue, especially in children…

View details →DOI: 10.1016/j.bbr.2024.115020
Negative / Null Result ReportOpen accessMedicine

Neither the number of feature dimensions nor their task relevance necessarily affect interocular grouping in binocular rivalry.

Pedziwiatr MA, Derda M, Bator W et al. · 2026 · Attention, perception & psychophysics

When one eye views half of stimulus A and half of stimulus B, and the other eye views the respective other halves, perception fluctuates. Among percepts reflecting monocular inputs (indicating typical binocular rivalry), percepts of…

View details →DOI: 10.3758/s13414-026-03265-0
Negative / Null Result ReportMedicine

Is employment status associated with baseline symptoms, engagement, and outcomes in naturalistic psychotherapy? Evaluation in a large community mental health agency.

Jiwani Z, Xie Q, Curtin JJ et al. · 2025 · Psychotherapy (Chicago, Ill.)

Employment status, an essential socioeconomic factor, may be an important driver of disparities in mental health and access to treatment. However, prior research has been inconclusive and utilized broad employment categories. The present…

View details →DOI: 10.1037/pst0000597
Negative / Null Result ReportOpen accessMedicine

Social isolation during adolescence alters novel object recognition memory, brain and gut gene expression, and microbiota composition in a sex-specific manner.

Ahmad R, Zobel G, Hannaford R et al. · 2026 · Brain, behavior, & immunity - health

Adolescent social isolation is a known risk factor for anxiety and depression related disorders, yet its effects on brain-gut communication and potential sex differences remain unclear. We hypothesised that isolation would heighten…

View details →DOI: 10.1016/j.bbih.2026.101284
Negative / Null Result ReportMedicine

Diverse social environments and 10-year all-cause mortality in a cohort of historically excluded racial/ethnic older adults: A latent class analysis of social integration.

Flores M, Boyd SM, O'Neill RM et al. · 2025 · Annals of epidemiology

Purpose The association between social integration and mortality in older adults from historically excluded groups may not align with the patterns observed in predominately white samples. We modeled latent groups of social integration and…

View details →DOI: 10.1016/j.annepidem.2025.08.037