Negative / Null Result ReportMedicine
Dubrovsky L, Pushkarsky T, Brichacek B et al. · 2026 · Microorganisms
Trained immunity (TRIM) enhances innate immune responses through epigenetic and metabolic reprogramming but may become maladaptive, contributing to chronic inflammation. In people living with HIV (PLWH), maladaptive TRIM has been proposed…
View details →DOI: 10.3390/microorganisms14020355 Negative / Null Result ReportMedicine
Tamoto M, Kai S, Yoshida H et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives To compare the real-world effectiveness of combined propofol and dexmedetomidine (PRODEX) sedation with propofol monotherapy on survival and postoperative delirium (POD) in a large nationwide cohort of patients undergoing…
View details →DOI: 10.1053/j.jvca.2025.11.037 Negative / Null Result ReportMedicine
Khun Jush B, Biswas MAAJ, Lim HJJ et al. · 2026 · Pancreas
Background Routine feeding tube (FT) placement during pancreaticoduodenectomy (PD) has not reduced complication rates. Nonetheless, FTs are often selectively placed in patients with poor nutritional status such as those with significant…
View details →DOI: 10.1097/mpa.0000000000002593 Negative / Null Result ReportMedicine
Bücken CA, Riesthuis P, Caon G et al. · 2026 · Memory (Hove, England)
False autobiographical memories can have serious implications in legal settings, where the case outcomes may hinge entirely on memory-based eyewitness testimony. This study investigated whether a sensitisation memory training could reduce…
View details →DOI: 10.1080/09658211.2025.2585095 Negative / Null Result Report
Sato T · 2025 · Preprint
Background: Active-fluidics phacoemulsification can maintain anterior chamber stability at lower intraoperative intraocular pressure (IOP) levels. However, whether reducing IOP alone—without additional stabilizing technologies such as the…
View details →DOI: 10.20944/preprints202512.0678.v1 Negative / Null Result ReportMedicine
Ruiz-Tagle C, Seguel R, Villarroel L et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background The duration of infectiousness following pulmonary tuberculosis treatment initiation remains uncertain. We aimed to assess whether a bundled intervention designed to decrease respiratory exposure was feasible and would reduce…
View details →DOI: 10.1093/cid/ciaf526 Negative / Null Result ReportMedicine
Ringer AJ, Hanel RA, Baig AA et al. · 2025 · Journal of neurointerventional surgery
Background The optimal duration for dual antiplatelet therapy (DAPT) after stent-assisted coiling (SAC) of intracranial aneurysms is unclear. Longer-term therapy may reduce thrombotic complications but increase the risk of bleeding…
View details →DOI: 10.1136/jnis-2024-021977 Negative / Null Result ReportMedicine
Bierer JD, Stanzel R, Henderson M et al. · 2026 · The Annals of thoracic surgery
Background Pediatric cardiac surgery with cardiopulmonary bypass (CPB) is associated with systemic inflammation. This trial aimed to determine whether continuous high-exchange ultrafiltration during CPB has a clinical immunomodulatory…
View details →DOI: 10.1016/j.athoracsur.2026.01.006 Negative / Null Result ReportMedicine
Khueangchiangkhwang S, Oida Y, Taguchi A et al. · 2026 · Parasitology international
Trichinella is a nematode that causes chronic infection via its larvae in muscle cells and remains a global health concern. Drug sensitivity, including to ivermectin (IVM), differs between intestinal adult worms (AW) and muscle larvae…
View details →DOI: 10.1016/j.parint.2025.103227 Negative / Null Result ReportMedicine
Dunkel K, Moroz MS, Suares B et al. · 2025 · The Journal of dairy research
This research article aimed to evaluate the effect of a commercial nutraceutical additive in milk replacer on the health and weight gain of dairy calves during the pre-weaning phase. A total of 126 female Holstein calves were randomly…
View details →DOI: 10.1017/s0022029925101568 Negative / Null Result ReportOpen accessMedicine
Meves V, Chamieh A, Mohamed M et al. · 2026 · Endoscopy international open
Background and study aims Previous studies in esophagogastroduodenoscopy or colonoscopy have demonstrated positive effects of music on patient anxiety and comfort. This study prospectively evaluated the effect of functional music on…
View details →DOI: 10.1055/a-2840-7071 Negative / Null Result ReportMedicine
Kashtiara A, Pauptit J, Thijs D et al. · 2025 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Objectives Enhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols may reduce pain, hospital length of…
View details →DOI: 10.1007/s00586-025-09640-z Negative / Null Result ReportOpen accessMedicine
Sielski W, Osęka T, Antolak A et al. · 2026 · Frontiers in endocrinology
Background Parathyroid preservation during total thyroidectomy with central neck dissection in papillary thyroid carcinoma remains challenging due to the glands' delicate vascular anatomy and risk of inadvertent devascularization or…
View details →DOI: 10.3389/fendo.2026.1811572 Negative / Null Result ReportMedicine
Palmier M, Ghorayeb G, Arhant G et al. · 2026 · Annals of vascular surgery
Background Supraceliac aortic cross-clamping can induce remote organ injury, particularly affecting the lungs through ischemia-reperfusion mechanisms. Pulmonary endothelial dysfunction plays a central role in acute lung injury, potentially…
View details →DOI: 10.1016/j.avsg.2026.01.011 Negative / Null Result ReportMedicine
García-García M, Mosqueda J, Escobar Cabrera JE et al. · 2025 · Toxicon
A recent clinical case involving a Poecilotheria regalis bite was treated with Mexican L. mactans antivenom (Aracmyn Plus, Silanes, Mexico), resulting in the improvement of some of the symptoms. This could be attributed to cross-reactivity…
Negative / Null Result ReportMedicine
Hooshiar MH · 2026 · The Journal of prosthetic dentistry
Statement of problem Artificial intelligence (AI) language models have been increasingly used for clinical decision-making in implant dentistry and for scholarly writing. Yet, their reliability, fabrication rates, and comparative…
View details →DOI: 10.1016/j.prosdent.2025.11.005 Negative / Null Result ReportMedicine
Tsakmaki PV, Tasoulis S, Georgakopoulos SV et al. · 2025 · International journal of neural systems
This research looks at the use of long-short-term memory (LSTM) networks to predict psychosis, in patients within the schizophrenia spectrum, based on Heart Rate Variability (HRV) data acquired from wearable devices. Our primary objective…
View details →DOI: 10.1142/s0129065725500649 Negative / Null Result ReportMedicine
Szabó D, Tóth A, Nagy CB et al. · 2025 · Orvosi hetilap
Introduction The glomus caroticum, located at the carotid bifurcation, contains chemoreceptors and is essential for the rapid physiological adaptation to changes in blood oxygen, carbon dioxide, and pH levels. Paragangliomas of the glomus…
View details →DOI: 10.1556/650.2025.33392 Negative / Null Result ReportMedicine
Sanak F, Iselin K, Kaufmann C et al. · 2026 · Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Purpose To analyze the effect of fasting on volume, growth factor, and lipid concentration in eye drops derived from autologous serum (AS) and leukocyte-poor platelet-rich plasma (LP-PRP). To assess changes in protein and growth factor…
View details →DOI: 10.1177/10807683251370853 Negative / Null Result ReportMedicine
Hughes C, Myers MA, Tickell-Painter M et al. · 2026 · Clinical biochemistry
Introduction The climate crisis is a health crisis, and healthcare contributes to this via consumption of resources, the release of greenhouse gases, and the generation of waste. Pathology testing underpins most healthcare, and the vast…
View details →DOI: 10.1016/j.clinbiochem.2025.111060 Negative / Null Result ReportMedicine
Regev-Yochay G, Barda N, Shusterman Y et al. · 2026 · NEJM evidence
Background In 2024, Israel faced a major West Nile virus (WNV) disease outbreak. We aimed to evaluate the efficacy and safety of WNV-neutralizing plasma for hospitalized patients with WNV disease. Methods We conducted a randomized,…
View details →DOI: 10.1056/evidoa2500169 Negative / Null Result ReportMedicine
Tavolinejad H, Bozorgi A, Emkanjoo Z et al. · 2025 · Journal of the American College of Cardiology
Background Vasovagal syncope (VVS) is a common yet challenging condition with limited effective treatments. Elastic compression stockings (ECS) have been proposed as a potential therapy, but their real-world effectiveness remains unclear.…
View details →DOI: 10.1016/j.jacc.2025.05.049 Negative / Null Result ReportOpen accessMedicine
Zhang F, Yu Z, Pan J et al. · 2026 · Jornal de pediatria
Objective This study aimed to investigate the risk factors for acute neurological complications (ANCs) in neonates with bacterial meningitis (NBM). Methods This retrospective study analyzed 68 neonates (aged 0-28 days) with bacterial…
View details →DOI: 10.1016/j.jped.2026.101533 Negative / Null Result ReportMedicine
Sanchis J, Bueno H, Martí Sánchez D et al. · 2025 · Heart (British Cardiac Society)
Background Clinical trials and meta-analyses indicate a reduced reinfarction risk with invasive management in older patients with non-ST-segment elevation myocardial infarction (NSTEMI). This study investigated whether similar benefits…
View details →DOI: 10.1136/heartjnl-2024-325254 Negative / Null Result Report
Qiao W, Liu L, Zhang X et al. · 2024 · Preprint
Abstract Background Subarachnoid anesthesia is the primary anesthetic method for elective cesarean section surgery, characterized by rapidly taking effect and reliable analgesia. However, subarachnoid anesthesia is prone to cause a high…
View details →DOI: 10.21203/rs.3.rs-5428405/v1 Negative / Null Result Report
Kashtiara A, Pauptit J, Thijs D et al. · 2025 · Preprint
Abstract BACKGROUND AND OBJECTIVES: Enhanced Recovery After Surgery (ERAS) protocols aim to improve surgical outcomes, by mitigating postoperative stress through multimodal perioperative care. In spinal surgery, such protocols—termed…
View details →DOI: 10.21203/rs.3.rs-7786792/v1 Negative / Null Result ReportOpen accessMedicine
Muir KJ, Maye A, McHugh MD et al. · 2025 · JAMA network open
Importance It is unknown if virtual nursing (VN) enhances care quality or improves the workload of bedside nurses in hospitals. Objective To describe what services VNs provide to patients and nurses in hospitals; to evaluate whether the…
View details →DOI: 10.1001/jamanetworkopen.2025.45597 Negative / Null Result ReportMedicine
Zhang J, Suo T, Cheng Y et al. · 2026 · Journal of investigative medicine : the official publication of the American Federation for Clinical Research
Hemophagocytic lymphohistiocytosis (HLH) secondary to visceral leishmaniasis (VL-HLH) is a severe and often fatal condition marked by systemic inflammation and immune dysfunction. In this retrospective cohort study at Shanxi Children's…
View details →DOI: 10.1177/10815589251390398 Negative / Null Result ReportMedicine
Smedemark SA, Jarbøl DE, Laursen CB et al. · 2026 · The lancet. Healthy longevity
Background Diagnosing acute respiratory conditions in adults older than 65 years is challenging due to age-related physiological changes, which increase diagnostic complexity and the risk of hospital admission. We investigated whether…
View details →DOI: 10.1016/j.lanhl.2026.100830 Negative / Null Result ReportOpen accessMedicine
Nakamura Y, Murata S, Yabe T et al. · 2026 · Cureus
Introduction C5 palsy is a disabling complication after posterior cervical decompression and fusion (PCDF). Whether C4/5 facetectomy reduces the incidence or improves the outcomes of C5 palsy remains uncertain. Therefore, this study aimed…
View details →DOI: 10.7759/cureus.109458 