Negative / Null Result ReportOpen accessMedicine (General)
Daniela Cristina Batista Pieroni, Naylla do Carmo Carlins, Pamela Polato et al. · 2017 · O Mundo da Saúde
Aging is associated with a decline in sensory acuity that may lead to impaired nutritional status. Thus, the study aimed to evaluate gustatory sensitivity in relation to the nutritional status of elderly women participating in an Activity Center for the Elderly (ACE). For that, an observational, analytical cross-sectional study was performed with elderly participants of an ACE, in Curitiba, PR. An anamnesis was applied to know and characterize the evaluated population, then an evaluation of the nutritional status was made through anthropometry. The taste sensitivity evaluation was carried out
Negative / Null Result ReportOpen accessEnvironmental sciences
El Sobky, Abeer, F, El Bokhary, M, AwadAllah, Hala, I et al. · 2018 · Journal of Environmental Science
This study was conducted to highlight the significant environmental factors that may have impacts on breast benign and malignant diseases. This study was carried out on one hundred females who came to radiology department to perform mammographic examination. A complete personal and family history of patients was taken, clinical examination was done, all cases were asked to fill a questionnaire about how often they deal with each item of the environmental factors including (alcohol, caffeine, smoking, use of some material that are commonly used in daily life and known to have estrogenic effect
View details →DOI: 10.21608/jes.2018.30843 Negative / Null Result ReportOpen accessAgriculture
Dirk Hays, Steve Hague, Seth C. Murray et al. · 2013 · Agronomy
To identify and develop drought tolerant maize (Zea mays L.), high-throughput and cost-effective screening methods are needed. In dicot crops, measuring survival and recovery of seedlings has been successful in predicting drought tolerance but has not been reported in C4 grasses such as maize. Seedlings of sixty-two diverse maize inbred lines and their hybrid testcross progeny were evaluated for germination, survival and recovery after a series of drought cycles. Genotypic differences among inbred lines and hybrid testcrosses were best explained approximately 13 and 18 days after planting, res
View details →DOI: 10.3390/agronomy3010135 Negative / Null Result ReportOpen accessNutrition. Foods and food supply
Suming Dai, Ping Wang, Sijia Wang et al. · 2025 · Frontiers in Nutrition
BackgroundExisting epidemiological studies investigated the association between a single vitamin and hypertension. However, the potential relationship between the level of circulating multivitamins and blood pressure has not been explored. We aimed to investigate the association between multiple fat-soluble vitamin levels and blood pressure.MethodsA total of 2052 participants with essential hypertension were sampled nationwide. The plasma concentrations of fat-soluble vitamins (A, E, D, and K) were assessed using liquid chromatography coupled with the mass spectrometry method. Participants wer
View details →DOI: 10.3389/fnut.2024.1502139 Negative / Null Result ReportOpen accessPublic aspects of medicine
Farshad Teymoori, Hossein Farhadnejad, Ebrahim Mokhtari et al. · 2021 · BMC Public Health
Abstract Background Inflammation is a precursor of chronic disease, which is affected by lifestyle and dietary habits. Recently empirical dietary inflammatory patterns (EDIP), dietary inflammation scores (DIS), and lifestyle inflammation scores (LIS) were developed to indicate lifestyle and dietary contributions in systemic inflammation. The current study aimed to investigate the associations between these indices and the incidence of diabetes among Tehranian adults. Methods A total of 4624 individuals, aged 20–75 years, who were free of diabetes at baseline (2008–2011), were followed for 5.71
View details →DOI: 10.1186/s12889-021-11327-1 Negative / Null Result ReportOpen accessMedicine
Gieira S Jones, Heather Spencer Feigelson, Roni T Falk et al. · 2019 · PLoS ONE
Background Breast density, as estimated by mammography, is a strong risk factor for breast cancer in pre- and postmenopausal women, but the determinants of breast density have not yet been established. The aim of this study was to assess if urinary estrogens or gut microbiota alterations are associated with mammographic density in postmenopausal women. Methods Among 54 cancer-free, postmenopausal controls in the Breast and Colon Health study, we classified low- versus high-density women with Breast Imaging Reporting and Data System (BI-RADS, 5th edition) mammographic screening data, then asses
View details →DOI: 10.1371/journal.pone.0216114 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Babak B. Navi, Mitchell S. V. Elkind, Cenai Zhang et al. · 2025 · Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Approximately 50% of strokes in patients with cancer are classified as cryptogenic after standard evaluation. Atrial cardiopathy could explain some cancer‐related cryptogenic strokes. However, the relationship between cancer and atrial cardiopathy is uncertain. Methods AND RESULTS We conducted a post hoc cross‐sectional analysis of baseline data collected from participants enrolled in ARCADIA (Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke), a clinical trial conducted from 2018 to 2023 at 185 sites. The analytical cohort presented herein included
View details →DOI: 10.1161/jaha.124.040543 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Shih-Hao Chen, Hung-Chieh Chang, Po-Wei Chiu et al. · 2023 · BMC Cardiovascular Disorders
Abstract Background Fever can occur after acute myocardial infarction (MI). The influence of body temperature (BT) after hospital arrival on patients with acute MI has rarely been investigated. Methods Patients who were diagnosed with acute MI in the emergency department (ED) of a tertiary teaching hospital between 1 January 2020 and 31 December 2020 were enrolled. Based on the tympanic temperature obtained at the ED triage, patients were categorized into normothermic (35.5°C-37.5°C), hypothermic ( 37.5°C) groups. The primary outcome was in-hospital cardiac arrest (IHCA), while the secondary o
View details →DOI: 10.1186/s12872-023-03372-y Negative / Null Result Report
Ade Harwoko, Lestari Kurniawati · 2022 · Jurnal Akademi Akuntansi
This study aims to determine changes in corporate tax aggressiveness after the application of Statement of Financial Accounting Standards (PSAK) 73. The sample of this research is the financial statements of pharmaceutical industry…
View details →DOI: 10.22219/jaa.v5i1.18732 Negative / Null Result ReportOpen accessChemistry
Tóth Štefan, Olexa Peter, Hertelyová Zdenka et al. · 2020 · Open Chemistry
The aim of this study was to detect the concentrations of PCSK9 in various subclinical stages of atherosclerosis and to highlight its relationship with inflammation. One hundred and fifty-nine healthy patients were divided into three groups, based on the extent of atherosclerotic changes in the carotid artery: a group without identifiable atherosclerosis, cIMT>75‰ and an asymptomatic plaque group. The PCSK9 was measured by ELISA and hsCRP by the immunoturbidimetric method. Vascular changes were identified by a carotid ultrasound. PCSK9 was elevated, when comparing the healthy group with the cI
View details →DOI: 10.1515/chem-2020-0147 Negative / Null Result ReportOpen accessMedicine (General)
Indra Hidayat, Erna Setiawati, Tanti Ajoe Kesoema et al. · 2023 · Jurnal Kedokteran Diponegoro
Background: Smartphone with all of its benefits make the majority of its users become too attached with the device that can fulfil their various needs. Due to its accessibility, an increase of daily screen time has also been observed which may have negative impacts on health, one of them being De Quervain’s Syndrome. De Quervain’s Syndrome is a type of Repetitive Strain Injury, affecting the thumb and wrist caused by a repetitious activity that puts burden or trauma to the aforementioned body parts. Objective: To assess the correlation between duration of screen time and method of handling sma
View details →DOI: 10.14710/dmj.v12i6.39048 Negative / Null Result ReportOpen accessHistory of scholarship and learning. The humanities
Salih Gülen, İsmail Dönmez, Fatma Betül Şengönül et al. · 2025 · SAGE Open
STEM education aims to develop 21st-century skills, support economic growth and promote gender equality in STEM fields. It is known that gender stereotypes play a significant role in the formation of STEM identity. The most important factor preventing some high school-level female students from pursuing STEM careers is their lack of participation in STEM activities. Female students in high schools have limited opportunities to explore or learn about STEM careers due to the emphasis on verbal and religious courses in their curriculum. However, it is known that women can work more autonomously i
View details →DOI: 10.1177/21582440251382631 Negative / Null Result ReportOpen accessMedicine
Memota Laishram, Krishnagopal Srikanth, AR Rajalakshmi et al. · 2017 · Journal of Clinical and Diagnostic Research
Introduction: Macular disease is the leading cause of low vision in the Western world. Drusen and pigmentary irregularities are common among the rural Northern Indian population. The disease process leads to loss of central vision, metamorphopsia, macropsia or micropsia and colour vision defect. Aim: To study the retinal sensitivity changes in macular diseases using microperimetry. Materials and Methods: It was an observational study, conducted in the Department of Ophthalmology at a rural tertiary care hospital. This study was started from December 2014 until June 2016, in all patients with m
View details →DOI: 10.7860/jcdr/2017/25799.10213 Negative / Null Result ReportOpen accessDiseases of the respiratory system
Amika K. Sood, Allison J. Burbank, Michael Lawson et al. · 2019 · Respiratory Research
Abstract Background Endotoxin is a component of particulate matter linked to respiratory disease. Our group has shown that experimental endotoxin inhalation challenge reproducibly triggers neutrophilic inflammation in the airways and in peripheral blood. Sputum induction is currently the only available method for assessing airway neutrophilia but is laborious and time-consuming. This analysis examined the correlation between systemic and airway inflammatory responses to endotoxin to determine if peripheral blood could serve as a surrogate marker for neutrophilic airway inflammation. Methods We
View details →DOI: 10.1186/s12931-019-1227-3 Negative / Null Result ReportOpen accessNuclear engineering. Atomic power
Jun Yeong Jo, Chi Bum Bahn, Hwasung Yeom · 2024 · Nuclear Engineering and Technology
The dissolved oxygen in a coolant can affect the oxidation properties of structural materials. A desirable oxide phase formation is achieved by manipulating the oxygen level in the coolant, which can mitigate structural material degradation in nuclear power plants. Therefore, the role of dissolved oxygen in the corrosion of structural materials in aqueous environments needs to be understood. In this study, a short-term corrosion test (up to 300 h) of Ferritic/Martensitic steels (F/M steels; FeCrW model alloys), namely, Fe12Cr1W, Fe9Cr1W, and Fe9Cr, in stagnant water at 360 °C was performed in
View details →DOI: 10.1016/j.net.2024.06.002 Negative / Null Result ReportOpen accessBiochemistry
Rostami Shilan, Fathollahpour Asadollah, Abdi Mohammad et al. · 2018 · Journal of Medical Biochemistry
Background: There is a paucity of studies regarding oxidative balance and selenium (Se) status in congenital hypothyroidism. Recently, more attention has been given to the use of Se supplementation as a new treatment for thyroid disorders. Oxidative stress increases in different thyroid disorders and causes many pathological outcomes. The present study aimed to determine the serum prooxidant-antioxidant balance (PAB), Se, thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentration in congenital hypothyroidism (CH) patients and the association of their probable change with hematolo
Negative / Null Result ReportOpen accessPediatrics
Fatma Sargin, Mehmet Alçı, Büşra Kaygusuz Aydemir et al. · 2026 · BMC Pediatrics
Abstract Background Childhood epilepsy is one of the most common neurological disorders worldwide, significantly affecting cognitive, emotional, and social development. As caregivers often seek medical guidance online, the readability, understandability, and quality of internet-based patient education materials (IPEMs) are crucial for health literacy and decision-making. This study evaluates the readability, understandability, quality, and popularity of online pediatric epilepsy materials in relation to established health communication standards. Methods A Google search using the term ‘epileps
View details →DOI: 10.1186/s12887-026-06602-2 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Huanhuan Zuo, Xiaochen Xie, Jiahuan Peng et al. · 2019 · Analytical Cellular Pathology
Recently, there has been an increasing interest in the potential clinical use of several inflammatory indexes, namely, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic-immune-inflammation index (SII). This study aimed at assessing whether these markers could be early indicators of pulmonary hypertension (PH) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). A total of 185 patients were enrolled in our retrospective study from January 2017 to January 2019. Receiver operating characteristic curve (ROC) and area under the
View details →DOI: 10.1155/2019/5189165 Negative / Null Result ReportOpen accessNursing
Simone Maria Muniz da Silva Bezerra, Eduardo Tavares Gomes, Paulo César da Costa Galvão et al. · Revista Brasileira de Enfermagem
ABSTRACT Objective: To characterize relations between spiritual well-being and hope of patients in the preoperative period of cardiac surgery. Method: Exploratory cross-sectional study with quantitative approach, performed in the infirmaries of a reference hospital in cardiology. We evaluated 69 patients hospitalized in preoperative period of myocardial revascularization, valve repair or replacement. Results: We verified that patients hold relevant scores of hope and welfare in all areas, being the existential well-being significantly lower than the religious one. The average of the spiritual
View details →DOI: 10.1590/0034-7167-2016-0642 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Ovi Sofia, Muna Amalia, Herryanto Thomassawa et al. · 2024 · Interdisciplinary Perspectives on Infectious Diseases
Introduction. The imbalance of the immune response is an important factor contributing to the incidence of ocular toxoplasmosis (OT). Regulatory T cells (Treg) play a key role in maintaining the balance between Th1 and Th17 immune responses, while interleukin-27 (IL-27) levels are related to the differentiation of Th17 cells. This study analyzes the differences in the number of Treg cells and the level of IL-27 between OT patients and seropositive individuals without ocular lesions and its correlation with retinal lesion size. Methods. This analytic observational study, conducted for 8 months,
View details →DOI: 10.1155/2024/3495376 Negative / Null Result ReportOpen accessOrthopedic surgery
Neal Singleton, Vaughan Poutawera · 2017 · Journal of Orthopaedic Surgery
Aim: It has been reported in the literature that patients with poor preoperative mental health are more likely to have worse functional outcomes following primary total hip and knee arthroplasty. We could find no studies investigating whether preoperative mental health also affects length of hospital stay following surgery. The aim of this study was to determine whether preoperative mental health affects length of hospital stay and long-term functional outcomes following primary total hip and knee arthroplasty. We also aimed to determine whether mental health scores improve after arthroplasty
View details →DOI: 10.1177/2309499017718902 Negative / Null Result ReportOpen accessGynecology and obstetrics
Divya Anantharaman, Aiswaryah Radhakrishnan, Vidhyalakshmi Anantharaman · 2023 · Journal of Pregnancy
Aim. Multisystemic physiological changes in pregnancy can result in tear film and refractive changes in the eye. We report dry eye prevalence in pregnant women using Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire. Methods. The SPEED questionnaire was self-administered cross-sectionally to 428 pregnant women (mean age: 26.8±4.4 years) with clinically confirmed pregnancy from two obstetric clinics in Chennai, India. Subjects with predisposing risk factors for dry eye were excluded from the study. Subjects were categorized as normal, moderate, and severe dry eye based on the SPE
View details →DOI: 10.1155/2023/3421269 Negative / Null Result ReportOpen accessAnimal culture
C.D. Araújo, G.S. Sanches, F. Borek et al. · 2023 · Arquivo Brasileiro de Medicina Veterinária e Zootecnia
ABSTRACT KIT protein is associated with the etiology of canine mast cell tumors (MCT); however, the expression patterns of KIT are highly variable. The aim of this study was to determine if KIT patterns are related with eosinophil count in MCT. Hematoxylin eosin and May Grünwald-Giemsa stain techniques were applied, histological grading and eosinophil counting were performed in 48 MCT samples. Immunohistochemical evaluation was performed with IL-5, VEGFr, and c-KIT antibodies. The percentage of immunolabeling with IL-5 and VEGFr was determined, and the samples incubated with c-KIT were graded
View details →DOI: 10.1590/1678-4162-12963 Negative / Null Result ReportOpen accessMedicine (General)
Manoochehr Nakhjavani, Firouzeh Asgarani, Fatemeh Esfahanian et al. · 2009 · Acta Medica Iranica
Accumulating evidence suggest that in patients with diabetes mellitus, increased rate of lipoprotein oxidation and oxidative stress have important role in diabetic angiopathy, including nephropathy. To evaluate the association of oxidized low- density lipoprotein (ox-LDL) with the development of diabetic nephropathy, plasma level of ox-LDL were measured in 70 diabetic patients with macro and 63 patients with normoalbuminuria. The plasma oxidized- LDL level in patients with macroalbuminuria was higher than those in normoalbuminuric group, (85.72 ± 32.92 mu/L versus 75.07 ± 26.46 u/L, P= 0.041).
Negative / Null Result ReportOpen accessDentistry
Dewi Kania Intan Permatasari, Tenny Setiani Dewi, Dewi Marhaeni Diah Herawati · 2021 · Dental Journal
Background: Taste disorders often occur in the elderly, which can have serious consequences on their health status. Zinc and saliva volume have a role in maintaining taste acuity, especially in the elderly. Purpose: This study was to determine the correlation between salivary zinc levels, salivary volume, and taste disorders in elderly patients. Methods: This was a cross-sectional research. Elderly patients with and without taste disorders were included in this study. Salivary zinc levels were measured using the Atomic Absorption Spectrometry (AAS) method. Salivary volume was measured using th
View details →DOI: 10.20473/j.djmkg.v54.i1.p31-34 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Dou Qu, Xiaoni Zhong, Guiyuan Xiao et al. · 2018 · International Journal of Infectious Diseases
Objective: To evaluate adherence to pre-exposure prophylaxis (PrEP) in a clinical trial of a population of men who have sex with men (MSM), to explore the influence of social psychology and objective factors (e.g., forgetting, too busy) on adherence, and to provide evidence for subsequent PrEP research. Methods: This study analyzed the data from the daily medication group within a PrEP study (a randomized placebo-controlled trial of oral tenofovir among MSM in Western China from April 2013 to March 2015). A total of 331 participants were analyzed. PrEP adherence was self-reported by the subjec
View details →DOI: 10.1016/j.ijid.2018.08.006 Negative / Null Result ReportOpen accessMedicine
Fatemeh Moghadasi-Boroujeni, Mansoureh Adel Ghahraman · 2020 · مجله پژوهش در علوم توانبخشی
Introduction: Romberg test is one of the balance screening tests. Since this test does not require special equipment, it is widely used in the evaluation of people suffering from balance disorders. This study aimed to determine the sensitivity of the Romberg test for the diagnosis of peripheral vestibular dysfunction compared with the caloric test that is the gold standard for the diagnosis of horizontal semicircular canal/superior vestibular nerve disorders.Materials and Methods: This study was a cross-sectional-comparative study and the sample was selected from those who referred to the audi
View details →DOI: 10.22122/jrrs.v16i0.3633 Negative / Null Result ReportOpen accessMedicine (General)
Joel Del Bel Pádua, Carolline Fontes Alves Mariano, Alexandre Todorovic Fabro et al. · 2024 · Biomarker Insights
Background: Immunohistochemical prognostic significance of the homologous recombination-related proteins RAD51, ATM, BRCA1, and BRCA2 is known in gastric adenocarcinoma, one of the deadliest cancers. Objective and design: This retrospective cohort study aimed to evaluate mRNA expression and promoter methylation of some homologous recombination-related genes in this neoplasm. Methods: We evaluated mRNA expression and methylation of RAD51 , ATM , ATR , BRCA1 , and BRCA2 in tumor and non-tumor frozen samples from gastrectomy specimens by RT-qPCR and MS-HRM, correlating our results with previous i
View details →DOI: 10.1177/11772719231225206 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Aves Editorial Aves Editorial · 2019 · Urology Research and Practice
Abstract Introduction: Lower urinary tract symptoms (LUTS) associated with BPH and erectile dysfunction (ED) are common problems in aging male. In this study, we aimed to determine the causes of the relationship between LUTS and ED, and the possible effects of body mass index (BMI), serum leptin, free testosterone (fT) and lipid levels on LUTS and ED etiology. Materials and Methods: Between June 2003 and February 2004, 46 patients were recruited in this study. All patients underwent physical examination including digital rectal examination, urine analysis, uroflowmetry and residual urine volum
Negative / Null Result ReportOpen accessGynecology and obstetrics
Baumann Gert, Gericke Christine, Mueller Simone et al. · 2010 · BMC Women's Health
Abstract Background Decreased levels of circulating bone marrow-derived progenitor cells have been associated with risk factors and cardiovascular diseases. Smoking is the most important modifiable risk factor for atherosclerosis in young women. The aim of this pilot study was to assess in healthy premenopausal women without other risk factors for cardiovascular disease the influence of nicotine abuse on the number of circulating progenitor cells in relation to endothelial function. Methods The number of endothelial progenitor cells, measured as colony-forming units in a cell-culture assay (EP
View details →DOI: 10.1186/1472-6874-10-20 