Negative / Null Result ReportOpen accessMedicine
Al Ayoubi O, Aldakak MA, Ibrahim B et al. · 2026 · Clinical case reports
Pleural tuberculosis is a common manifestation of extrapulmonary tuberculosis; however, its diagnosis remains challenging in paucibacillary disease, where clinical presentation may be atypical and microbiological tests frequently yield…
View details →DOI: 10.1002/ccr3.72205 Negative / Null Result ReportMedicine
Nielsen SM, Russell EM, Ellsworth RE et al. · 2025 · Journal of the National Comprehensive Cancer Network : JNCCN
Background The presence of variants of uncertain significance (VUS) should not influence clinical management; however, prior studies on breast cancer-related health care utilization in women with VUS versus negative germline genetic test…
View details →DOI: 10.6004/jnccn.2025.7011 Negative / Null Result ReportMedicine
Salman E · 2026 · Indian journal of medical microbiology
Background The primary reason for increased lab use is inappropriate or needless test requests. Our study examined the benefits of repeated antinuclear antibody (ANA) testing and the reasons for ANA test requests in accordance with…
View details →DOI: 10.1016/j.ijmmb.2025.101035 Negative / Null Result ReportMedicine
Watanabe K, Takahashi H, Narumi R et al. · 2025 · The journal of obstetrics and gynaecology research
Non-invasive prenatal testing (NIPT) is a screening method that analyzes cell-free DNA (cfDNA) in maternal plasma to detect major aneuploidies. However, NIPT can fail to identify subtle chromosomal aberrations. We report a case in which…
View details →DOI: 10.1111/jog.70168 Negative / Null Result ReportOpen accessMedicine
Sridapan T, Jaturapaktrarak C, Rujirawat T et al. · 2026 · Journal of fungi (Basel, Switzerland)
Pythiosis is an emerging infectious disease caused by the oomycete Pythium insidiosum , affecting humans and animals primarily in subtropical and tropical regions. The pathogen is commonly found in swampy environments, and exposure can…
View details →DOI: 10.3390/jof12050351 Negative / Null Result ReportOpen accessMedicine
Meng S, Zhao W, Zhang H et al. · 2026 · EJHaem
Objective To retrospectively analyze the early efficacy and safety of azacitidine plus lisaftoclax in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome with increased blasts (MDS-IB), providing a reliable clinical…
View details →DOI: 10.1002/jha2.70305 Negative / Null Result ReportMedicine
Castle PE, Befano B, Hyer M et al. · 2026 · Journal of the National Cancer Institute
Background We demonstrated that cervical cancer risk following any screening result is lower if there is a known prior negative screening history vs an unknown screening history. We extended these findings to look at how screening performs…
View details →DOI: 10.1093/jnci/djaf317 Negative / Null Result ReportMedicine
Çubuk F, Öksüz C, Öz M · 2026 · Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
Objective A substantial proportion of urine cultures in patients with suspected urinary tract infections (UTIs) yield negative results. This study aimed to evaluate whether parameters from automated urinalysis could predict the likelihood…
View details →DOI: 10.1016/j.jiac.2026.102904 Negative / Null Result ReportOpen accessMedicine
Sato R, Takasaka N, Hosaka Y et al. · 2025 · BMC infectious diseases
Background The T-SPOT.TB assay is widely used for the adjunctive diagnosis of tuberculosis (TB). However, clinicians often encounter false-negative T-SPOT.TB results. The extent of TB spread may influence host immune functions, which can…
View details →DOI: 10.1186/s12879-025-10777-x Negative / Null Result ReportOpen accessMedicine
Sripa J, Suebsamran P, Pangjit K · 2026 · BMC infectious diseases
Background Opisthorchiasis remains an important public health problem in Southeast Asia and is strongly associated with cholangiocarcinoma. Although stool-based diagnosis is widely used, its sensitivity is limited in light infections,…
View details →DOI: 10.1186/s12879-026-13445-w Negative / Null Result ReportOpen accessMedicine
Unubol N, Ayaş M, Uyar NY et al. · 2025 · Microorganisms
In recent years, the World Health Organization has highlighted biofilm-derived multidrug-resistant bacteria as a critical threat to both global health and the environment. Although various testing methods are available, crystal violet and…
View details →DOI: 10.3390/microorganisms14010021 Negative / Null Result Report
AL-Saeedi A, Abdulamir AS, Aufi IM et al. · 2025 · Preprint
Abstract Background The widespread use of accurate real-time RT-PCR tests for community individuals is a critical approach to managing the disease and reducing COVID-19 transmission effectively. In addition, serological ELISA assays are…
View details →DOI: 10.21203/rs.3.rs-8233598/v1 Negative / Null Result ReportOpen accessMedicine
Mukherjee S, Fujiwara Y, Fountzilas C et al. · 2025 · Cancer medicine
Background Preoperative chemoradiation (CRT) followed by surgery for localized esophageal and gastroesophageal junction adenocarcinoma (EGAC) is a standard of care with a pathologic complete response (pCR) rate of 20%. We evaluated a novel…
View details →DOI: 10.1002/cam4.70835 Negative / Null Result ReportMedicine
Fu Q, Chen Y, Huang D et al. · 2023 · Annals of surgical oncology
Background Folinic acid, fluorouracil, irinotecan, and oxaliplatin (FOLFIRINOX) or modified FOLFIRINOX (mFFX) is the first-line standard of care for metastatic pancreatic adenocarcinoma; effective and safe treatment strategies are needed…
View details →DOI: 10.1245/s10434-023-13383-w Negative / Null Result ReportMedicine
Hiester A, Che Y, Lusch A et al. · 2023 · European urology
Background Primary retroperitoneal lymph node dissection (RPLND) for clinical stage (CS) IIA/B seminoma without adjuvant treatment is an experimental treatment to avoid radiotherapy- or chemotherapy-related toxicity from standard…
View details →DOI: 10.1016/j.eururo.2022.10.021 Negative / Null Result ReportMedicine
Ibrahim AM, Saleem A, Faisal MS et al. · 2025 · Digestive diseases and sciences
Background and aims Multitarget stool DNA (mt-sDNA) testing is a non-invasive colorectal cancer (CRC) screening tool, but false-negative results may delay diagnosis. Understanding which patients are more likely to have advanced lesions…
View details →DOI: 10.1007/s10620-025-09595-7 Negative / Null Result ReportOpen accessMedicine
Kundu A, Majumder D, Das D et al. · 2026 · Cureus
Introduction Latent tuberculosis infection (LTBI) is still neglected and acts as a barrier to the tuberculosis (TB) elimination goal of the National Tuberculosis Elimination Programme (NTEP) by 2025 sustaining TB transmission, particularly…
View details →DOI: 10.7759/cureus.104511 Negative / Null Result ReportMedicine
López-Morales A, Benito D, Gerrikagoitia X et al. · 2026 · Canadian journal of microbiology
Influenza A infection is frequently detected in marine mammals causing mortality events of different magnitude. In recent years, the highly pathogenic avian influenza (HPAI) H5N1 virus (clade 2.3.4.4b) has been rapidly expanding and…
View details →DOI: 10.1139/cjm-2025-0211 Negative / Null Result ReportMedicine
Corma-Gómez A, Santos M, Martín-Carmona J et al. · 2026 · AIDS patient care and STDs
To evaluate the proportion of gay, bisexual, and other men who have sex with men (GBMSM) with ongoing high-risk sexual practices not engaged in care, and to assess linkage to and retention in care following a community-based intervention.…
View details →DOI: 10.1177/10872914261429704 Negative / Null Result ReportOpen accessMedicine
Stewart SF, Enne VI, Pandolfo AM et al. · 2026 · Antimicrobial resistance and infection control
Background Rapid molecular diagnostics such as the BioFire FilmArray Pneumonia Panel (the Pneumonia Panel) can improve antibiotic stewardship by supporting doctors to make more targeted antibiotic prescribing decisions faster compared to…
View details →DOI: 10.1186/s13756-025-01690-8 Negative / Null Result ReportMedicine
Sheng D, Wang S, Xiao Z et al. · 2026 · European archives of psychiatry and clinical neuroscience
BACKGROUND: Observational studies have reported associations between retinal thickness and Alzheimer’s disease (AD); however, the causal relationship remains uncertain. OBJECTIVE: To investigate the potential causal relationships between…
View details →DOI: 10.1007/s00406-025-02184-9 Negative / Null Result ReportMedicine
Schwartz A, Mikati S, Knipper F et al. · 2025 · Applied biosafety : journal of the American Biological Safety Association
Background The COVID-19 pandemic highlighted critical shortages in personal protective equipment (PPE), particularly respirators, which limited healthcare workers' safety worldwide. Decontamination and reuse of PPE, including powered-air…
View details →DOI: 10.1089/apb.2025.0006 Negative / Null Result ReportOpen accessMedicine
Ahogni I, Avanon H, Hueha C et al. · 2026 · Malaria journal
Background Accurate interpretation and recording of malaria rapid diagnostic tests (RDTs) are critical for case management and surveillance in malaria-endemic settings. In Benin, where over 90% of malaria diagnoses rely on RDTs, concerns…
View details →DOI: 10.1186/s12936-026-05871-7 Negative / Null Result ReportMedicine
Bulut C, Arslan Z, Aydoğdu M et al. · 2026 · Forensic science international
Rising global alcohol consumption is a major public health and safety concern. Over the last decade, undeclared alcohol consumption has increasingly come into focus due to high inflation that has led many individuals to resort to unhealthy…
View details →DOI: 10.1016/j.forsciint.2025.112764 Negative / Null Result ReportMedicine
Kavunga-Membo H, Chi HF, Emperador DM et al. · 2026 · The Lancet. Infectious diseases
Background Mpox has spread to 36 countries in Africa, yet many face challenges achieving nationwide PCR-based testing due to cost and limited access in remote and rural areas. Point-of-care antigen-based rapid diagnostic tests (RDTs) might…
View details →DOI: 10.1016/s1473-3099(26)00141-6 Negative / Null Result ReportMedicine
Watanabe T, Hirano T · 2026 · Clinical medicine insights. Pediatrics
Objective The importance and effectiveness of Newborn hearing screening (NHS) have been widely recognized. However, there are a few cases of false-negative NHS results. Hearing loss in children causes various disorders. Therefore,…
View details →DOI: 10.1177/11795565261443150 Negative / Null Result ReportOpen accessMedicine
Mangiaterra T, Chabay P, Bellan C et al. · 2026 · Frontiers in immunology
Epstein-Barr virus (EBV) infects more than 90% of the global population and is etiologically linked to a wide spectrum of lymphoid and epithelial malignancies. Although its role as an oncogenic virus is well established, the mechanisms…
View details →DOI: 10.3389/fimmu.2026.1742214 Negative / Null Result ReportMedicine
Wang X, Albayda J, Paik JJ et al. · 2025 · Rheumatology (Oxford, England)
Objective This study aims to evaluate the diagnostic accuracy of CA-125 and PET/CT in detecting cancer among adult patients with idiopathic inflammatory myopathy (IIM). Methods We conducted a retrospective study of a single-centre cohort…
View details →DOI: 10.1093/rheumatology/keae470 Negative / Null Result Report
Mann L, Samp P, Schäefer JH et al. · 2025 · Preprint
Background: / Objectives; After negative results of the SAMMPRIS-trial the indication for endovascular treatment of atherosclerotic intracranial artery stenosis (ICAS) was widely restricted. It was the aim of our study to report whether…
View details →DOI: 10.20944/preprints202511.1539.v1 Negative / Null Result ReportMedicine
Kimura K, Kuwata T, Hiraoka Y et al. · 2026 · Journal of human genetics
Multigene panel testing (MGPT) is increasingly used for diagnosing hereditary cancers; however, its application in cascade testing remains limited, and the psychological impact on unaffected relatives is not well understood. This…
View details →DOI: 10.1038/s10038-026-01464-z 