A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21733 results · page 518 of 725
Cera, Araujo, Lima et al. · 2026 · Developmental psychobiology
Tantrums are widely discussed in human development literature and are typically defined as displays of frustration or anger. In behavioral ecology, they are hypothesized to function as a strategy for securing greater maternal investment.…
Wang, Zhang, Ye et al. · 2026 · Molecular immunology
Dendritic cell (DC) migration-triggered T cell activation is a pivotal event in transplant rejection. Previous studies have established a critical role of the C-type lectin receptor 2（CLEC-2）and podoplanin (PDPN) axis in…
Xiang, Wei, Guo et al. · 2026 · Biomedicines
Objectives : To investigate the effects of Roxadustat and recombinant human erythropoietin (rHuEPO) on glycemic control and glycated hemoglobin (HbA1c) in non-dialysis type 2 diabetic kidney disease (DKD) patients with anemia. Methods :…
Chalasani, Vuppalanchi, Noureddin et al. · 2026 · Hepatology (Baltimore, Md.)
Belapectin reduced variceal development in a subgroup of patients with MASH cirrhosis. We report the efficacy and safety of belapectin in patients with MASH cirrhosis and portal hypertension without varices at baseline. NAVIGATE was a…
Hayashi-Wells, Phark, Duarte · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
To evaluate the effect of saliva contamination and a 10-MDP-containing cleaner (Katana Cleaner; Kuraray Noritake, Japan) on the shear bond strength (SBS) of an ultra-mild universal adhesive applied in self-etch mode to human dentin.…
Veneri, Nobili, Bolelli et al. · 2026 · Acta stomatologica Croatica
This in vitro preliminary study investigated how different ozone formulations affect the adhesion, surface topography, and interfacial ion release of two pediatric bioactive restorative materials. Standardized enamel and dentin surfaces…
Wang, Gui, Mei et al. · 2026 · Clinics (Sao Paulo, Brazil)
To compare outcomes of short-course versus longer-course antibiotic regimens in mechanically ventilated adult patients with sepsis due to pneumonia. The authors performed a retrospective cohort study using the MIMIC-IV database…
Waldron, Suttawireesan, Fatimah et al. · 2026 · Journal of neuroendocrinology
Sex differences have been noted in the prevalence and severity of several neurological and mental health disorders. Midbrain dopaminergic activity is implicated in the etiology of many of these disorders and therefore may also contribute…
Zhang, Di, Qiao et al. · 2026 · BMC oral health
BACKGROUND: Bioceramic sealers have been increasingly applied in endodontics due to their excellent sealing properties and biocompatibility. However, the sealing performance of different bioceramic sealers and their removability during…
Lee, Chao, Shen et al. · 2026 · BMC pulmonary medicine
BACKGROUND: The optimal surgical strategy for very elderly patients (≥ 75 years) with stage I non–small cell lung cancer (NSCLC) remains uncertain. METHODS: We retrospectively analyzed 390 patients with pathologic…
Nesova, Vorobeva, Ryabov · 2026 · The Indian journal of medical research
Background and objectives The risk-treatment paradox (RTP) has not been studied in very high-risk patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). We aimed to describe the cohort of very high-risk NSTE-ACS patients,…
Bayraktar, Karaca, Ekşılı et al. · 2026 · Restorative dentistry & endodontics
This in vitro study evaluated the effects of various sugary and non-sugary beverages on the color change of a dental composite and the subsequent bleaching efficacy. Forty-nine disc-shaped composite samples (Neo Spectra ST, Dentsply…
Tavares, Ramalho, da Silva et al. · 2026 · Breast cancer research and treatment
Triple-negative breast cancer (TNBC) is an aggressive subtype characterized by early relapse and limited therapeutic options. Carboplatin added to anthracycline/taxane neoadjuvant chemotherapy (NACT) raises pathologic complete response…
Caldonazo, Scheler, Fischer et al. · 2026 · American heart journal plus : cardiology research and practice
Device-associated endocarditis is a potentially life-threatening condition that typically requires the removal of the cardiac implantable electronic device (CIED). The role of routine coronary angiography (CAG) as part of preoperative…
Alzraikat, Al-Hiyasat, Jamous et al. · 2026 · Biomaterial investigations in dentistry
This study evaluated the effectiveness of acids on calcium silicate cement surface hardness, perforation, and their impact on root dentine microstructure. Root dentine discs were exposed to hydrochloric, acetic, and citric acids. Fourier…
Chen, Ma, Zhang · 2026 · Accident; analysis and prevention
Automated vehicles (AVs) are designed to improve traffic safety, mobility, and driver comfort; however, their benefits depend on the widespread adoption of AVs. As full market penetration remains unlikely in the near term, AVs will…
Atef Abdelsattar Ibrahim, Gouda Kamal, Zid et al. · 2026 · World journal of clinical pediatrics
Obesity and overweight are major public health challenges and are associated with autonomic imbalance and decreased heart rate variability (HRV), a non-invasive indicator of cardiovascular risk. Omega-3 polyunsaturated fatty acids have…
Ahmed, AbuMostafa · 2026 · Scientific reports
This investigation sought to evaluate the comparative influence of different irrigation activation protocols-ultrasonic, sonic, XP-Endo Finisher, and manual dynamic activation (MDA)-on the nanohardness, elastic modulus, flexural strength,…
Zhan, Hao, Li et al. · 2026 · Frontiers in medicine
Currently, there are few reports on the impact of preoperative anticoagulant administration on perioperative coagulation function and blood loss. Therefore, this study observed the effects of preoperative anticoagulant administration on…
Qin, Liu, Cheng et al. · 2026 · Ecology letters
Although habitat area and isolation are considered key factors influencing plant disease and herbivory, their specific mechanisms remain underexplored within island biogeography. We investigated the direct and indirect effects (via…
Genel, Alzarouni, Mirza et al. · 2026 · Neuro-oncology advances
Recent evidence has demonstrated a tight relationship between neuronal activity and glioblastoma (GBM) growth, involving novel mechanisms such as neuron-glioma synapses and tumor microtube networks. Seizure activity and antiepileptic drug…
Da Silva Souza, De Souza, Dos Santos et al. · 2026 · Frontiers in public health
Children with low motor coordination tend to engage in less physical activity. They are more likely to gain weight, establishing a bidirectional relationship, as weight gain may further restrict their participation in physical activity.…
Liang, Zhu, Han et al. · 2026 · Zhongguo shi yan xue ye xue za zhi
To explore the effect of body mass index (BMI) on the efficiency of hematopoietic stem cell (HSC) mobilization. A retrospective analysis was conducted on the clinical data of 158 healthy donors who underwent peripheral blood HSC…
Cummings, Hodges, Theodore · 2026 · Psychonomic bulletin & review
Listeners can use lexical information to accommodate ambiguity in speech input. Some evidence suggests that lexically guided perceptual learning persists over time. However, other evidence suggests that lexically guided perceptual learning…
Schwarz, Watzenboeck, Stuempflen et al. · 2026 · European radiology
Prenatal alcohol exposure (PAE) of the fetus may result in physiognomic alterations and/or impediment of cognitive development, summarized as fetal alcohol spectrum disorders (FASDs). Although alcohol is metabolized in the liver, the…
Razmeh, Karimi, Dashti et al. · 2026 · Journal of neurology
Hypoxic ischemic encephalopathy (HIE) is a severe brain injury that can lead to death and long-term disability. HIE can be treated with therapeutic hypothermia, and various adjuvant treatments (such as melatonin) are also utilized.…
van Amstel, Simons, Kooreman et al. · 2026 · Breast (Edinburgh, Scotland)
In clinically node-positive (cN+) patients, radioactive iodine ( 125 I) seeds can be considered to mark metastatic axillary lymph nodes before neoadjuvant therapy (MARI-procedure) but potential therapeutic effects remain unclear. This…
Yıldız, Top, Yıldız et al. · 2026 · Mediterranean journal of hematology and infectious diseases
Stenotrophomonas maltophilia ( S. maltophilia ) is a multidrug-resistant pathogen frequently isolated in hospital-acquired pneumonia and represents a significant clinical challenge. This study aimed to investigate the risk factors…
Narimichi, Komaki, Suzuki et al. · 2026 · Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Solar UV comprises UVA and UVB; each exerts distinct biological effects, while their combined impact is not yet fully understood. We previously reported that human keratinocytes exposed to UVA1 followed by UVB irradiation exhibited severe…
Timothee, Bliss, Blumenthal et al. · 2026 · Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
The primary objective is to determine whether patients undergoing osseous microvascular free flap reconstruction of head and neck defects have higher inpatient pain requirements than those undergoing nonosseous reconstruction. Secondary…