A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20261 results in Negative / Null Result Report · page 511 of 676
Headrick KC, Pellegrini BA, Santiago EM et al. · 2026 · AoB PLANTS
Herbivory is particularly threatening to young plants that lack the resources needed to survive an attack. Seeds and seedlings should thus benefit greatly from using pre-attack cues to induce defence before damage. Locomotion mucus from…
Schiff KJ, Schiff DS, Moy BJ et al. · 2025 · PNAS nexus
Does the implementation of external oversight in policing improve public perceptions of police legitimacy? Civilian review boards (CRBs) are frequently promoted as mechanisms to enhance the legitimacy of police agencies by providing…
Li J, Jin T, Chi Y et al. · 2025 · Neuropsychiatric disease and treatment
Purpose Reducing electroconvulsive therapy (ECT)'s cognitive burden without compromising efficacy is critical. Although magnetic seizure therapy (MST) shows comparable symptom remission in schizophrenia, its neuroanatomical…
Lee P, Li J, Rafiee Y et al. · 2025 · Scientific reports
Facial attractiveness influences important social outcomes and most studies investigating possible predictors of facial attractiveness have tested for effects of shape symmetry, averageness (i.e., the converse of distinctiveness), and…
Torres-Banduc MA, Thapa RK, Pérez MA et al. · 2025 · Shoulder & elbow
Background The isokinetic shoulder profile is commonly used to assess injury risk in overhead sports. CrossFit athletes are vulnerable to shoulder injuries due to high-load, high-repetition demands. This exploratory study aimed to evaluate…
Potter CE, Lew-Williams C · 2025 · Behavioral sciences (Basel, Switzerland)
It is a widely held belief that bilingual infants benefit from hearing each of their languages spoken by different people, as speakers could serve as a cue for separating the two languages. However, it is not yet known whether infants…
Vilotijević A, Mathôt S · 2024 · Cerebral cortex (New York, N.Y. : 1991)
In brightness, the pupil constricts, while in darkness, the pupil dilates; this is known as the pupillary light response (PLR). The PLR is driven by all photoreceptors: rods and cones, which contribute to image-forming vision, and…
Lipman SA · 2022 · Frontiers in health services
Objective Earlier research has shown that individuals' subjective life expectancy (SLE) affects health state valuation with time trade-off (TTO). Individuals with longer expected life durations are less willing to trade-off life duration,…
Kang HS, Han KM, Kim JH et al. · 2025 · Biomedicines
Background/Objectives: Atopic dermatitis (AD) is a common chronic inflammatory skin disease that may influence cancer risk through immune dysregulation and chronic inflammation. The association between AD and colorectal cancer (CRC)…
Overmann L, Steinmeier K, Brandl A et al. · 2026 · Journal of clinical medicine
Background: Chronic low back pain (CLBP) and depression often co-occur. This study compared a fascia-focused physiotherapeutic program with a conventional physiotherapeutic and relaxation-based program in psychosomatic inpatients with CLBP…
Eiling I, Sigurdsson S, Kuhn-Keller JA et al. · 2026 · Neurology
Background and objectives Cerebral "dirty-appearing" or "diffusely abnormal" white matter (DAWM) represents subtle white matter abnormalities that are associated with progression of cerebral small vessel disease (cSVD), but the association…
Hjelholt TJ, Johnsen SP, Brynningsen PK et al. · 2023 · Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Considerable uncertainty prevails regarding risk factors for recurrent fracture among older patients with hip fracture. We aimed to investigate the relationship between prefracture stroke history, baseline mobility, and the risk of…
Hatano M, Kimura Y, Okada A et al. · 2026 · RMD open
Objectives Owing to the underrepresentation of early-stage disease in randomised trials and inconsistent clinical evidence, using oral bisphosphonates to prevent incident osteoarthritis in adults with osteoporosis lacks consensus. We aimed…
Nielsen MB, Çolak Y, Benn M et al. · 2024 · Cardiovascular research
Aims Adiponectin may play an important protective role in heart failure and associated cardiovascular diseases. We hypothesized that plasma adiponectin is associated observationally and causally, genetically with risk of heart failure,…
Choi SW · 2024 · PloS one
This study explains how the gap between theory and empirical research hinders scientific progress in the area of international political economy. To demonstrate this point, I use Chen's Extended Dependence Theory, which challenges liberal…
Vaes AW, Spruit MA, Goswami N et al. · 2022 · Microvascular research
Background Regular exercise positively affects cardiovascular physiology, translating into the adequate capacity of microvascular blood vessels to dilate in response to acute bouts of exercise. However, this remains unstudied in patients…
Foulds C, Khudiakova V, Surtees ADR · 2026 · Scientific reports
Theory of mind is an important skill to function in society. There is evidence that anxiety can impair the ability to use this skill effectively; however, current research is inconclusive, uses heterogeneous measures of theory of mind, and…
Niu D, Ye L, Gu X et al. · 2026 · Diabetology & metabolic syndrome
BACKGROUND: Although serum bilirubin levels have been linked to diabetic retinopathy (DR), their causal role remains uncertain. We aimed to assess the relationship between bilirubin levels and diabetic retinopathy (DR) using both…
Zhang Z, Lian H, Huang L et al. · 2026 · International journal of surgery (London, England)
Background Sublobar resection, including wedge resection (WR) and segmental resection (SR) has been considered for early-stage non-small-cell lung cancer (NSCLC). However, the optimal sublobar approach continues to be a subject of…
Ostrega J, Shiramizu V, Lee AJ et al. · 2024 · Scientific reports
Vocal attractiveness influences important social outcomes. While most research on the acoustic parameters that influence vocal attractiveness has focused on the possible roles of sexually dimorphic characteristics of voices, such as…
Schauer G, Grassi PR, Gharabaghi A et al. · 2024 · Neuroscience of consciousness
The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential transcranial magnetic stimulation studies have revealed differences in conscious perception following parietal…
Friehs MA, Brauner L, Frings C · 2021 · Experimental brain research
Stopping an already initiated action is crucial for human everyday behavior and empirical evidence points toward the prefrontal cortex playing a key role in response inhibition. Two regions that have been consistently implicated in…
Lazic A, Thomsen MR, Brown CC et al. · 2025 · Preventive medicine reports
Objective The Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides access to nutritional resources to low-income children starting at birth through enrollment in kindergarten or turning five years old. The…
Liu S, Nolin DA, Kitts JA · 2024 · Social networks
Recent studies have found order effects in social network data collection, where later names on a roster receive fewer nominations. Some thus argue for randomizing name orders or sampling peer names for survey rosters. We model order…
Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open
Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…
Shi P, Wei G, Li Z et al. · 2026 · Brain and behavior
Background Toxoplasma gondii (T. gondii) is a ubiquitous protozoan parasite capable of establishing lifelong latent infections in the central nervous system. Previous epidemiological studies have suggested a potential association between…
Pott J, Mason AM, Salo V et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects lipid metabolism. A recent study identified an association between rs562556 within the PCSK9 gene and breast cancer survival (BCS), suggesting PCSK9 inhibition as an…
Liu B, Alexopoulou ZS, van Ede F · 2024 · Communications psychology
Brain circuitry that controls where we look also contributes to attentional selection of visual contents outside current fixation, or content within the spatial layout of working memory. A behavioural manifestation of this contribution…
Hornsey MJ, Spence JL, Chapman CM · 2026 · Nature communications
Effective altruists argue that charitable giving is over-influenced by empathic responses and should instead be guided by cost-benefit analyses about the effectiveness of giving. To provide insight into the extent to which empathy and…
Pott J, Mason A, Salo V et al. · 2025 · Preprint
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) is well known for its causal effects on the lipid metabolism. A recent study identified an association between rs562556 within PCSK9 and breast cancer survival (BCS). It was…