A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19885 results in Negative / Null Result Report · page 511 of 663
Gallardo VJ, Caronna E, Rosell-Mirmi J et al. · 2026 · The journal of headache and pain
Background It remains unclear whether high-frequency migraine is associated with objective markers of possible neuroaxonal injury and potential expression of neurodegenerative hallmarks. We compared serum and MRI biomarkers in…
Abel DB, Fulford D, Fiszdon JM · 2026 · The Journal of nervous and mental disease
Aim Researchers have studied mechanisms underlying social motivation in schizophrenia, including reward learning, hostile attribution bias, and defeatist performance beliefs. Yet, existing work is limited by the use of laboratory paradigms…
McCabe SC, Ramirez K, Dyer S et al. · 2026 · American journal of audiology
Purpose Follow-up care after hearing aid fitting is recommended, yet clinicians lack data on the expected number of follow-up appointments needed and which patients require more support. This study aimed to characterize follow-up service…
Fernández Pérez ER, Humphries SM, Lynch DA et al. · 2026 · Annals of the American Thoracic Society
Rationale Quantitative CT using multiple instance learning (MIL)-usual interstitial pneumonia (UIP) classifier and data-driven textural analysis (DTA) provides objective and reproducible measurements of disease pattern and extent,…
Wienhold S, Volkmer N, Denk B et al. · 2026 · Preprint
Abstract Trust enables cooperation, but it also exposes individuals to social risks. The physiological dynamics of trust in real-world interactions remain poorly understood. In this study, we investigated whether interpersonal…
Onyedire NG, Ikenegbu T, Edward PU et al. · 2026 · Preprint
Abstract Background University students with physical impairments often face burnout in mainstream settings due to stigma, social barriers, and inadequate support. While social anxiety may heighten risk, self-concept and social support…
Kopatz M, Wagner W, Neuendorf C et al. · 2026 · Preprint
Class composition is a key contextual factor in students’ academic development. Prior research has mainly focused on class mean achievement, yet less is known about other composition characteristics, possible differences for students with…
Berkley S, Hoyt LT, Zeiders KH et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
This study used multilevel growth modeling to examine associations between ethnic-racial socialization (ERS) and sociopolitical development among undergraduates of color (N = 125) attending predominantly White institutions during the 2016…
MacAllister WS, Désiré N, Brooks BL · 2026 · The Clinical neuropsychologist
Objective There is strong support for the use of performance validity tests (PVTs) in all neuropsychological evaluations, however, research examining racial, ethnic, and linguistic differences in failure rates remains scarce, particularly…
Bagchi B, Van Vlaenderen L, Wheeler T et al. · 2026 · Preprint
Maternally transmitted Wolbachia bacteria are common in insects, with many strains altering host reproduction through cytoplasmic incompatibility (CI). CI kills embryos fertilized by Wolbachia -bearing males unless those embryos also carry…
Sahlan RN, Frietchen R, Billman Miller MG et al. · 2025 · Suicide & life-threatening behavior
Objective Although previous research has established bidirectional links between many eating disorder (ED) symptoms and suicidal ideation (SI), no research has examined how symptoms of avoidant/restrictive food intake disorder (ARFID)…
Hauser N, Sommerfield D, Nguyen J et al. · 2026 · Anaesthesia
Introduction Peri-operative respiratory adverse events remain a major cause of morbidity and mortality in children undergoing general anaesthesia; those with asthma are at higher risk. The aim of this feasibility study was to determine…
Fasanu O, Oloruntola FP · 2026 · Preprint
Abstract Background Why is there low behavioural response towards cancer and high blood pressure (HBP) screening uptake among Nigerians? The present study addressed this question by using the theory of planned behaviour (TPB) to…
Li M, He H, Dong L et al. · 2026 · Journal of psychosomatic research
Background Patients post hepatocellular carcinoma (HCC) surgery encounter physiological challenges as well as psychological and social adaptation problems，yet the trajectory and predictors of their psychosocial adjustment (PSA) remain…
Tezanos KM, Simeone A, Gerson R et al. · 2026 · Child psychiatry and human development
Youth are presenting to Emergency Departments (EDs) following a suicide-related crisis at higher rates and younger ages. Clinicians lack tools to effectively discern suicide risk in younger patients. The present investigation examines how…
Joshi S, Jahn KN · 2026 · Ear and hearing
Objectives Cochlear implants (CIs) enable people with moderate-to-profound sensorineural hearing loss to perceive sounds, but perceptual outcomes with a CI remain highly variable from person to person. Individuals who wear their CI…
Ciriello GD, Colonna D, Morelli C et al. · 2026 · Indian pacing and electrophysiology journal
Fetal echocardiography plays a pivotal role in the diagnosis and management of fetal arrhythmias, allowing evaluation of the electrophysiological mechanism and guiding appropriate medical therapy. Herein, we describe our ten-year…
Chan ACY, Stephan AT, Sneed RS · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences
Objectives While the intensity of grandparent caregiving has been linked to older adults' health, limited research has examined the bidirectional associations between grandparenting intensity and health, particularly within grandparent…
O'Shaughnessy J, Brufsky AM, Layeequr Rahman R et al. · 2026 · JCO precision oncology
Purpose Randomized trials have not demonstrated clear benefit from anthracyclines for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HER2-) early breast cancer (EBC). The MammaPrint 70-gene…
Xiao H, Warner E, Ryan J et al. · 2026 · Cancer causes & control : CCC
Purpose Cancer-related cognitive impairment (CRCI) is a common concern among breast cancer (BC) patients receiving chemotherapy, yet predictors of short-term cognitive change remain unclear. This study examined whether baseline…
Tsokolas ZE, Asante I, Tsiknia AA et al. · 2026 · Preprint
Abstract Apolipoprotein E ε4 (APOE4) is the strongest genetic risk factor for late-onset Alzheimer's disease (AD), yet whether its pathogenic effects are driven by HDL lipidation state or by elevated APOE4 levels in the CNS remains…
William JB, Chieng D, Crowley R et al. · 2026 · JACC. Clinical electrophysiology
Background Left atrial (LA) enlargement is commonly used in patient selection for catheter ablation. However, its role in predicting postablation outcomes in persistent atrial fibrillation (AF) remains uncertain. Objectives The study goal…
Alpert E, Kaplan A, Nelson D et al. · 2026 · Psychological trauma : theory, research, practice and policy
Objective Among patients with co-occurring posttraumatic stress disorder (PTSD) and substance use disorders (SUDs), little is known about early PTSD treatment processes, including treatment preference and outcome expectancy. This study…
Cohen H, Toro D, Zuluaga D et al. · 2026 · Clinical transplantation
Introduction To evaluate donor-stratified graft and patient survival following kidney transplantation (KT) for lithium-associated end-stage kidney disease (ESKD). Methods This retrospective analysis utilized the Organ Procurement and…
Yang L, Zhang H, Wei Y et al. · 2026 · American journal of hematology
Immunosuppressive therapy (IST) is the standard treatment for acquired pure red cell aplasia (aPRCA), but predictors of treatment response and long-term prognosis remain unclear. The clinical significance of somatic mutations in aPRCA is…
Vellore AJ, Bhatia S, Kann MR et al. · 2026 · JMIR XR and spatial computing
Background Augmented reality (AR) can provide risk-free training for medical trainees, yet little is known about which learner characteristics facilitate adoption or inform training design. Objective We aimed to identify which learner…
Denfeld QE, Hiatt SO, Dieckmann NF et al. · 2026 · The Journal of cardiovascular nursing
Many adults with heart failure (HF) are physically frail, and HF self-care behaviors, especially symptom monitoring and management (SMM), may affect physical frailty; however, the association between SMM behaviors and physical frailty has…
Sharpe L, Shaw J, Boyse JB et al. · 2026 · British journal of health psychology
Aims Asthma is a chronic condition characterized by episodes of breathlessness. Although common, asthma is known to be associated with higher rates of depression and anxiety, but there are few studies that have attempted to document the…
Ming X, Liu H, Yang J et al. · 2026 · Applied psychology. Health and well-being
Prior studies suggest that mindfulness interventions are viable for alleviating insomnia; however, the potential bidirectional link between mindfulness and insomnia warrants a longitudinal study. This study investigates the bidirectional…
Yanowitz T, Patel A · 2025 · Preprint
Abstract OBJECTIVE: To evaluate whether delayed cord clamping (DCC) duration predicts hyperbilirubinemia and phototherapy days among preterm infants of different gestational ages. STUDY DESIGN: In this retrospective cohort study, 2,421…