Negative / Null Result ReportOpen accessMedicine
Ohmori T, Hiraoka A, Totsugawa T et al. · 2025 · Annals of thoracic surgery short reports
Background It is still controversial whether prosthesis-patient mismatch (PPM) adversely affects long-term outcomes after aortic valve replacement (AVR). The aim of this study was to examine whether flow-adjusted pressure gradient is a…
View details →DOI: 10.1016/j.atssr.2024.07.008 Negative / Null Result ReportOpen accessMedicine
Yii F, Strang N, Bernabeu MO et al. · 2024 · Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)
Introduction Research assuming linearity has concluded that corneal biomechanics are compromised in high myopia. We investigated whether this assumption was appropriate and re-examined these associations across different levels of myopia.…
View details →DOI: 10.1111/opo.13313 Negative / Null Result ReportMedicine
Ivimey-Cook ER, Shorr S, Moorad JA · 2023 · Evolution; international journal of organic evolution
Maternal senescence is the reduction in individual performance associated with increased maternal age at conception. When manifested on adult lifespan, this phenomenon is known as the "Lansing Effect." Single-species studies report both…
View details →DOI: 10.1093/evolut/qpac045 Negative / Null Result ReportOpen accessMedicine
Gharibian D, Medeiros M, Dion PA et al. · 2026 · Tremor and other hyperkinetic movements (New York, N.Y.)
Essential Tremor (ET) is a highly heterogeneous movement disorder with a strong genetic basis. However, the etiology of ET is unclear, largely due to its clinical heterogeneity and frequently observed comorbidities. We conducted a…
View details →DOI: 10.5334/tohm.1168 Negative / Null Result ReportMedicine
Heneghan JA, Akande MY, Ramgopal S et al. · 2024 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Objectives To describe change in Functional Status Scale (FSS) associated with critical illness and assess associated development of new morbidities with PICU readmission. Design Retrospective, cross-sectional cohort study using the…
View details →DOI: 10.1097/pcc.0000000000003542 Negative / Null Result ReportMedicine
Osias E, Cale M, Saffari P et al. · 2024 · Orbit (Amsterdam, Netherlands)
Purpose To understand how thyroid eye disease (TED) impacts buccal fat pad (BFP) volume. Methods In this cohort study, computed tomography (CT) scans and charts of adult patients with and without TED were obtained from an institutional…
View details →DOI: 10.1080/01676830.2023.2192787 Negative / Null Result ReportOpen accessMedicine
Schuetze BA · 2026 · Cognitive research: principles and implications
A genre of online videos known as "sludge content" has recently surged in popularity. These videos typically present two clips simultaneously, with one primary and one muted secondary video, creating an intentionally overstimulating…
View details →DOI: 10.1186/s41235-026-00720-2 Negative / Null Result ReportOpen accessMedicine
Nair A, Medina J · 2024 · Attention, perception & psychophysics
Our tactile perception is shaped not only by somatosensory input but also by visual information. Prior research on the effect of viewing touch on tactile processing has found higher tactile detection rates when paired with viewed touch…
View details →DOI: 10.3758/s13414-024-02959-7 Negative / Null Result ReportOpen accessMedicine
Stretti F, Parvin R, Fariña Nuñez MT et al. · 2026 · Neurosurgical review
Cranioplasty (CP) is performed after decompressive craniectomy (DC), with complication rates of 15-40%. Risk factors and ideal timing for CP are unclear. This study investigates risk factors for complications after CP and the best time to…
View details →DOI: 10.1007/s10143-025-03993-1 Negative / Null Result ReportMedicine
Ratner K, Zhu G, Li Q et al. · 2023 · Journal of adolescence
Introduction Supportive adults are a critical component of effective out-of-school time (OST) youth programs, yet the short-term dynamics that underlie their role are poorly understood. Within GripTape, a US-wide self-driven learning…
View details →DOI: 10.1002/jad.12149 Negative / Null Result ReportOpen accessMedicine
Rosoff DB, Bell AS, Wagner J et al. · 2024 · Cellular and molecular gastroenterology and hepatology
Background & aims Observational studies have linked lipid-lowering drug targets pro-protein convertase subtilisin/kexin 9 (PCSK9) and HMG-CoA reductase (HMGCR) with adverse liver outcomes; however, liver disease incidence varies across…
View details →DOI: 10.1016/j.jcmgh.2023.09.001 Negative / Null Result ReportMedicine
Kube T, Herzog P · 2023 · Journal of clinical psychology
Background Recent research suggests that dysfunctional expectations are a particularly important subtype of cognitions in depression. However, it is unclear whether depressive symptoms are related to the presence of negative expectations,…
View details →DOI: 10.1002/jclp.23442 Negative / Null Result ReportOpen accessMedicine
Xie H, Ratner K, Estevez M et al. · 2026 · Journal of research on adolescence : the official journal of the Society for Research on Adolescence
The Claremont Purpose Scale (CPS) was designed to assess youth purpose, but the English version has not yet undergone rigorous psychometric evaluation among adolescents. Prior validation efforts have also mostly relied on white-majority…
View details →DOI: 10.1111/jora.70215 Negative / Null Result ReportMedicine
Guerrero-Aranda A, Enríquez-Zaragoza A, López-Jiménez K et al. · 2024 · Clinical EEG and neuroscience
Background. Sleep is an activation procedure and is considered the most potent and best-documented modulator of seizures and interictal epileptiform discharges (IEDs) on electroencephalogram (EEG). The precise role of sleep deprivation in…
View details →DOI: 10.1177/15500594221142397 Negative / Null Result ReportOpen accessMedicine
Fasha TA, Rajuddin R, Dewi TP et al. · 2026 · Narra J
Endometriosis affects approximately 10% of women of reproductive age and is characterized by the presence of endometrial tissue outside the uterine cavity. Diagnostic delays are common due to nonspecific symptoms and the absence of…
View details →DOI: 10.52225/narra.v6i1.2988 Negative / Null Result ReportOpen accessMedicine
Liu Y, Zhang H · 2025 · Medicine
This study aimed to investigate the bidirectional causal relationship between celiac disease (CD) and the risk of Alzheimer disease (AD) or frontotemporal dementia (FTD) using Mendelian randomization (MR), in order to clarify prior…
View details →DOI: 10.1097/md.0000000000045059 Negative / Null Result Report
Kösem A, Dai B, McQueen JM et al. · 2022 · Preprint
During listening, brain activity tracks the rhythmic structures of speech signals. Here, we directly dissociated the contribution of neural tracking in the processing of speech acoustic cues from that related to linguistic processing. We…
View details →DOI: 10.1101/2022.07.25.501422 Negative / Null Result ReportMedicine
Jozefowiez J, Huff AG, Petruzzo L et al. · 2026 · Journal of experimental psychology. Animal learning and cognition
The expression of an association between a conditioned stimulus (CS) and an aversive unconditioned stimulus (US) can be weakened by presenting the CS by itself (extinction [Ext]), pairing it with an appetitive US (counterconditioning…
View details →DOI: 10.1037/xan0000430 Negative / Null Result Report
Van der Snickt T, Ailliet S, Bassini S et al. · 2025 · Preprint
Enzyme-free isothermal amplification methods offer a promising alternative to enzymatic assays for nucleic acid detection, particularly in low-resource settings. The nonenzymatic isothermal strand displacement and amplification (NISDA)…
View details →DOI: 10.1101/2025.05.19.654176 Negative / Null Result Report
Walleczek J, von Stillfried N, Schmidt S et al. · 2025 · Preprint
This metascientific project studied the replicability of Bem Experiment 1, which had claimed a precognitive effect, i.e., the ability to successfully guess the outcome of future random events (Bem. J Pers Soc Psychol. 2011;100: 407-25).…
View details →DOI: 10.31234/osf.io/53ckh_v1 Negative / Null Result ReportMedicine
Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
View details →DOI: 10.1016/j.metabol.2025.156417 Negative / Null Result ReportMedicine
Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in veterinary science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
View details →DOI: 10.1016/j.rvsc.2025.105794 Negative / Null Result ReportMedicine
Willroth EC, Young G, Ford BQ et al. · 2025 · Psychological science
Certain emotion-regulation strategies (e.g., reappraisal) are associated with better well-being and are therefore seen as adaptive (health-promoting) strategies. However, it is unlikely that any strategy is adaptive regardless of context.…
View details →DOI: 10.1177/09567976251335567 Negative / Null Result ReportMedicine
Argenbright CM, Scully IF, Flores D et al. · 2025 · The journal of pain
Pain is a multidimensional phenomenon, encompassing affective-motivational, cognitive-evaluative, and sensory-discriminative domains. Understanding these components is crucial for effective diagnosis and management, particularly in…
View details →DOI: 10.1016/j.jpain.2025.105486 Negative / Null Result ReportMedicine
Goldberg SB, Baldwin SA, Flynn AWP et al. · 2026 · Clinical psychological science : a journal of the Association for Psychological Science
While it is known that therapists vary in effectiveness, it is unclear what therapist-level characteristics predict this variation. We conducted a large-scale, preregistered study ( n = 97 therapists from the United States and Canada, n =…
View details →DOI: 10.1177/21677026261424222 Negative / Null Result Report
Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
View details →DOI: 10.31234/osf.io/d3x9p_v1 Negative / Null Result Report
Kakeya H, Umeno Y · 2025 · Preprint
Background Kayano et al. estimated the potential number of COVID-19 cases and deaths in Japan from February 17 to November 30, 2021, in a counterfactual scenario where no vaccination was implemented. Their model predicted 63.3 million…
View details →DOI: 10.1101/2025.02.08.25321916 Negative / Null Result Report
Stawiany K, Kozak K, Sokołowska Z · 2025 · Preprint
The study explores the hypothesis that individuals show greater sympathy towards coherent name-face pairs compared to incoherent pairs, replicating the effect observed by Barton and Halberstadt. A structured questionnaire was designed…
View details →DOI: 10.20944/preprints202501.0057.v1 Negative / Null Result Report
Dede A, Xiao W, Vaci N et al. · 2023 · Preprint
Abstract Neurodevelopmental disorders are difficult to diagnose, requiring expert clinicians and subjective judgements. Consequently, there has been interest in finding quantitative biomarkers for some disorders using resting state…
View details →DOI: 10.21203/rs.3.rs-2982892/v1 Negative / Null Result Report
Marshall K, Thothathiri M · 2023 · Preprint
Comprehenders make predictions about the meaning and structure of linguistic information as the utterance unfolds. However, when the actual content does not match the expectation, costly reanalysis processes are required. Previous work has…
View details →DOI: 10.31234/osf.io/9qvyf