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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19879 results in Negative / Null Result Report · page 501 of 663

Negative / Null Result ReportOpen accessMedicine

Preschoolers' Early Sentence Comprehension: Comparing Bilingual and Monolingual Children and the Role of Executive Function and Vocabulary Development.

Rodenhurst N, Messenger K · 2026 · Developmental science

Previous research into children's comprehension of syntactic structures has investigated early awareness of transitive and intransitive structures amongst monolingual children but research into bilingual children's understanding of the…

View details →DOI: 10.1111/desc.70232
Negative / Null Result ReportOpen accessMedicine

Selective Modulation of Evidence Accumulation by Hippocampal Theta Oscillations During Mnemonic Decision-Making.

Robins PL, Gilbert JR, Luber B et al. · 2026 · Human brain mapping

A core function of episodic memory is to distinguish between overlapping experiences by converting similar inputs into distinct, non-overlapping representations, a process termed pattern separation. While anatomical models emphasize the…

View details →DOI: 10.1002/hbm.70529
Negative / Null Result Report

No evidence of differences between hierarchical versus distinction relations in self-based ACT exercises: A critical reanalysis of Foody et al. (2013) and Foody et al. (2015)

Hussey I · 2026 · Preprint

The evidential link between Relational Frame Theory (RFT) and Acceptance and Commitment Therapy (ACT) is a matter of on-going debate. Foody et al. (2013) is frequently cited as evidence for ACT’s concept of Self-as-Context and as evidence…

View details →DOI: 10.31234/osf.io/ab7de_v5
Negative / Null Result ReportOpen accessMedicine

Mortality risks associated with short-term exposure to ultrafine particles in London and the West Midlands.

Nenon D, Fuller G, Masselot P et al. · 2026 · Environmental epidemiology (Philadelphia, Pa.)

Background Some research has suggested that ultrafine particles (UFP), with an aerodynamic diameter less than 100 nm, might be the most harmful component of ambient particulate matter air pollution on human health. In the United Kingdom,…

View details →DOI: 10.1097/ee9.0000000000000449
Negative / Null Result Report

No evidence of differences between hierarchical versus distinction relations in self-based ACT exercises: A critical reanalysis of Foody et al. (2013) and Foody et al. (2015)

Hussey I · 2026 · Preprint

The evidential link between Relational Frame Theory (RFT) and Acceptance and Commitment Therapy (ACT) is a matter of on-going debate. Foody et al. (2013) is frequently cited as evidence for ACT’s concept of Self-as-Context and as evidence…

View details →DOI: 10.31234/osf.io/ab7de_v4
Negative / Null Result Report

No evidence of differences between hierarchical versus distinction relations in self-based ACT exercises: A critical reanalysis of Foody et al. (2013) and Foody et al. (2015)

Hussey I · 2026 · Preprint

The evidential link between Relational Frame Theory (RFT) and Acceptance and Commitment Therapy (ACT) is a matter of on-going debate. Foody et al. (2013) is frequently cited as evidence for ACT’s concept of Self-as-Context and as evidence…

View details →DOI: 10.31234/osf.io/ab7de_v3
Negative / Null Result Report

No evidence of differences between hierarchical versus distinction relations in self-based ACT exercises: A critical reanalysis of Foody et al. (2013) and Foody et al. (2015)

Hussey I · 2026 · Preprint

The evidential link between Relational Frame Theory (RFT) and Acceptance and Commitment Therapy (ACT) is a matter of on-going debate. Foody et al. (2013) is frequently cited as evidence for ACT’s concept of Self-as-Context and as evidence…

View details →DOI: 10.31234/osf.io/ab7de_v1
Negative / Null Result Report

No evidence of differences between hierarchical versus distinction relations in self-based ACT exercises: A critical reanalysis of Foody et al. (2013) and Foody et al. (2015)

Hussey I · 2026 · Preprint

The evidential link between Relational Frame Theory (RFT) and Acceptance and Commitment Therapy (ACT) is a matter of on-going debate. Foody et al. (2013) is frequently cited as evidence for ACT’s concept of Self-as-Context and as evidence…

View details →DOI: 10.31234/osf.io/ab7de_v2
Negative / Null Result ReportMedicine

Reward learning and attention in risky alcohol use: Absence of Pavlovian influences but altered response bias in high-risk drinkers.

Van der Wielen I, Mrkonja L, Wiers R et al. · 2026 · Behavioural brain research

Reward learning can contribute to addictive behaviors by shaping attention and action selection. While reward-associated stimuli are known to capture attention, it remains unclear whether such learning can also guide behavior without…

View details →DOI: 10.1016/j.bbr.2026.116228
Negative / Null Result ReportMedicine

Vitamin Supplementation and Cardiovascular Disease.

Lipman ET, Frishman WH · 2026 · Cardiology in review

Cardiovascular disease remains the leading cause of morbidity and mortality worldwide. Given the global burden, the potential role of micronutrients-particularly vitamins-in modifying cardiovascular risk has been a topic of intense…

View details →DOI: 10.1097/crd.0000000000001180
Negative / Null Result ReportOpen accessMedicine

Healthy Food Voucher Programs: Global Evidence on Structure, Implementation, and Nutrition-Related Outcomes.

Lara-Arevalo J, Corvalan C, Pemjean I et al. · 2025 · Advances in nutrition (Bethesda, Md.)

Healthy food voucher programs (HFVPs) provide lower-income participants with benefits to purchase healthy, nutrient-dense foods and are a promising strategy for improving dietary and nutritional outcomes. HFVPs can complement policies…

View details →DOI: 10.1016/j.advnut.2025.100530
Negative / Null Result Report

The Evaluation of Devaluation: Deficient outcome devaluation leads to wrongly considering goal-directed actions as habits

Vázquez-Millán A, Martínez-López P, Romero MR et al. · 2026 · Preprint

Habits are stimulus-driven responses that are produced independently of the current outcome value. They enable efficient actions in familiar contexts while freeing up cognitive resources. Habits are expected to influence behavior after…

View details →DOI: 10.31234/osf.io/zh39t_v5
Negative / Null Result Report

Association of educational attainment with incident orientation impairment among Chinese older adults with and without stroke: evidence from a longitudinal study with external validation

Shi C, Wu L, Yang Q et al. · 2026 · Preprint

Abstract Background Orientation impairment is an early and clinically meaningful marker of cognitive vulnerability in older adults and is associated with subsequent functional decline, dementia, and mortality. Although stroke is a…

View details →DOI: 10.21203/rs.3.rs-9092847/v1
Negative / Null Result ReportMedicine

Do Anti-immigration Rhetoric and Policy Impact Reporting of Intimate Partner Violence To Police Among Latina/e Survivors in the United States? A Comparative Interrupted Time Series Study.

Bevilacqua K, Gemmill A, Jackson D et al. · 2026 · Journal of immigrant and minority health

Latina/e women in the United States (US) experience intimate partner violence (IPV) at similar or lower rates than other women but worse IPV-related health outcomes, perhaps due to barriers to help-seeking. IPV reporting to police is one…

View details →DOI: 10.1007/s10903-026-01877-0
Negative / Null Result ReportMedicine

Genetic Susceptibility to <i>Helicobacter pylori</i> Infection and Pancreatic Cancer Risk: A Two-Sample Mendelian Randomisation Study.

Yang NY, Ke TM, Huang Y et al. · 2026 · Life (Basel, Switzerland)

Background/Objectives : Pancreatic cancer is one of the most lethal malignancies, with poor survival and few established modifiable risk factors. While Helicobacter pylori ( H. pylori ) infection is a known cause of gastric cancer, its…

View details →DOI: 10.3390/life16020284
Negative / Null Result Report

Ischemic stroke after bivalent mRNA COVID-19 vaccination and influenza vaccination during the 2022-2023 season: a multi-site self-controlled case series study

Xu S, Sy LS, Hong V et al. · 2026 · Preprint

Background The Vaccine Safety Datalink (VSD) detected a statistical signal for ischemic events (ischemic stroke or transient ischemic attack) following bivalent mRNA COVID-19 vaccination through prospective surveillance during 2022-2023.…

View details →DOI: 10.64898/2026.05.20.26353716
Negative / Null Result ReportOpen accessMedicine

Interferon-γ +874T/A polymorphism, <i>Toxoplasma gondii</i> serostatus, and risk of paranoid schizophrenia in males: a case-control study.

Braun D, Olmer A · 2026 · Frontiers in psychiatry

Background and hypothesis Toxoplasma gondii (TG) exposure and host immunogenetic variation have been implicated in psychosis. Interferon-gamma (IFN-γ) is central to TG control; the IFN-γ +874T/A polymorphism has been linked to variability…

View details →DOI: 10.3389/fpsyt.2026.1771815
Negative / Null Result ReportMedicine

Is selenate a diabetogenic form of selenium? Evidence from a natural experiment in Northern Italy.

Vinceti M, Vicentini M, Ottone M et al. · 2026 · Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)

Background Consistent evidence from randomized controlled trials has shown that overexposure to selenium induces type 2 diabetes. However, uncertainties remain about the specific species and doses of selenium that trigger such diabetogenic…

View details →DOI: 10.1016/j.jtemb.2026.127838
Negative / Null Result ReportMedicine

Geomagnetic Constraints on Millicharged Dark Matter.

Arza A, Gong Y, Shu J et al. · 2026 · Physical review letters

Millicharged particles are well-motivated dark matter candidates arising in many extensions of the standard model. We show that, despite their tiny coupling e_{m} to photons, millicharged dark matter (mDM) in the Earth's geomagnetic field…

View details →DOI: 10.1103/8xqd-dbrz
Negative / Null Result ReportMedicine

Association of oral metoprolol exposure during heart failure hospitalization with death or readmission at 28-days and 6-months using a propensity score overlap-weighted EHR analysis.

Ishaqui AA, Alsaleh EA, Khalil AAA et al. · 2026 · Naunyn-Schmiedeberg's archives of pharmacology

Heart failure (HF) hospitalization is a high-risk transition period with frequent early post-discharge events; we evaluated whether oral metoprolol exposure during the index HF hospitalization is associated with lower all-cause death…

View details →DOI: 10.1007/s00210-026-05184-1