A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20261 results in Negative / Null Result Report · page 495 of 676
McAulay J, Querejeta JI, Eskelson BNI et al. · 2025 · Forest Ecology and Management.
1.Exacerbated by climate change, wildfires in British Columbia, Canada, have increased in extent and severity, impacting forests, including commercially valuable species like interior Douglas-fir (Pseudotsuga menziesii var. glauca).…
Broll A, Goldhacker M, Hahnel S et al. · 2025 · Journal of dentistry
Objectives This retrospective in vitro study evaluated the impact of input data quantity on the morphology of dental crowns generated by AI-based software. The hypothesis suggests that increased input data quantity improves the quality of…
Kavanagh EW, Joynt AT, Pion AR et al. · 2025 · Preprint
Cystic Fibrosis (CF) is a life-limiting genetic disorder caused by deleterious variants in the CFTR gene that results in altered mucous impairing the airway epithelia. Durable correction of these variants in airway cells remain a…
Bui TH, Le DP, Ho TD et al. · 2026 · Veterinary journal (London, England : 1997)
This study investigated the effects of Saccharomyces cerevisiae fermentation-derived postbiotics (SCFP) on reproductive performance and immunity of sows and their offspring from gestation to weaning in a low biosecurity, small-scale pig…
Klimek K, Kierys A, Matwijczuk A et al. · 2025 · Carbohydrate Polymers.
This work aimed to compare the biomedical potential of thermally obtained hydrogels consisting of curdlan and a curdlan–whey protein isolate mixture. The purpose of this paper was also to investigate and explain the mechanisms responsible…
Toshida K, Sugitani Y, Itoh S et al. · 2025 · Preprint
Abstract Background: Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality worldwide. While systemic therapies have improved outcomes, predicting tumor histopathology remains difficult. Machine learning (ML) offers a…
Farmany A, Razavi P, Parsania M et al. · 2025 · Preprint
Abstract Purpose To evaluate whether Rose Bengal (RB) with sodium nitrite (NaNO₂) and acyclovir derived carbon quantum dots (CQDs) can photodynamically inactivate herpes simplex virus type 1 (HSV 1) in vitro. Methods Acyclovir-derived CQDs…
Özgen-Top Ö, Aysert-Yildiz P, Tekin-Taş Z et al. · 2026 · Infectious diseases now
Objectives This study aimed to compare the effectiveness and safety of standard-dose and high-dose tigecycline in pneumonia caused by carbapenem-resistant Acinetobacter baumannii (CRAB). Methods This retrospective, propensity score-matched…
Yuan Y, Huang M, Peng J et al. · 2026 · La Radiologia medica
Purpose To evaluate the value of whole-lesion histogram analysis derived from mono-exponential, bi-exponential, and stretched-exponential DWI models in differentiating benign from malignant breast lesions and exploring molecular subtypes.…
Xavier S, Al-Saabary H, Foran D et al. · 2026 · Neuroscience
Post-traumatic stress disorder (PTSD) is strongly linked to neuroinflammation, with immune activation in brain regions such as the amygdala and hippocampus potentially contributing to its long-term persistence. Yet, whether…
Ratanawongphaibul K, Wongwachira C, Suwajanakorn D et al. · 2025 · Preprint
Abstract Purpose To compare the SITA Standard 24-2 and SITA Faster 24-2C tests in patients with chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy and those at high risk. Methods A prospective, cross-sectional study of 75 participants who…
Abdel-Kerem A, Wei W, Calzado A et al. · 2025 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose This study aimed to evaluate the impact of integrating smart glasses with a pharmacy compliance mobile application on the efficiency of completing medication unit inspections. The goal was to compare traditional inspection methods…
Clark AR, Adams AT, McKinley TO et al. · 2026 · The Journal of surgical research
Introduction Volumetric muscle loss (VML) resulting from severe extremity injuries in combat remains a significant clinical challenge, particularly in austere environments. Current research emphasizes the development and evaluation of…
Li J, Wang X, Li J et al. · 2025 · Journal of medical virology
The recently mutated Omicron variant of SARS-CoV-2 exhibits extremely high infectivity and strong evolution and immune escape capabilities. Given the unique epidemic prevention policies of China, we collected 16 sets of sera from…
van Strien-Knippenberg IS, Timmermans DRM, Weber M et al. · 2025 · Health communication
This study aimed to assess whether, in the context of communicating risk-based breast cancer screening results, visualizations of risk information consisting of an icon array depicting quantified breast cancer risk and simplified drawings…
Nakano H, Nakagawa K, Ikuno T et al. · 2024 · Preprint
Objective Post-stroke spasticity prevalence increases with time from stroke onset, and negatively impacts the patient’s quality of life. Vibratory stimulation (VS) to the spastic muscles can reduce spasticity, whereas action observation…
Kuziboev B, Pícha K, Nazif Çatık A et al. · 2025 · Journal of environmental management
This research is the first to investigate the effect of low-carbon energy risk on the diversification of energy sources. To this end, a sample of 64 countries from 2000 to 2018 is analysed. For empirical estimations, we employ the Method…
Moura RA, Bisiau A, Freeman D et al. · 2025 · Preprint
Background: Perioperative fluid therapy can influence oxygen delivery and tissue oxygenation, but its effects in horses are poorly understood. Objectives: To compare two intraoperative fluid administration strategies on peripheral tissue…
Hibner A, Tong MK, Liu L et al. · 2025 · Preprint
Abstract OBJECTIVE: To investigate single versus combination hemodynamic parameters on intraventricular hemorrhage (IVH) or mortality in preterm infants. STUDY DESIGN: Data from 482 infants under 32 weeks gestational age were analyzed,…
Far ZS, Nematollahi MA, Hosseini SV et al. · 2025 · Preprint
Abstract Arthrospira platensis, commonly known as Spirulina , is an industrially cultivated cyanobacterium due to its high content of phycobiliproteins, mainly phycoerythrin, phycocyanin, and allophycocyanin. In this work, a low-cost…
Godoi Filho JRM, Abreu TFO, Vieira QR et al. · 2026 · Journal of motor behavior
We investigated the influence of mental fatigue on motor performance and learning. Additionally, we examined whether practicing under mental fatigue induces resilience in future performance under similar fatigue conditions. Ninety-two…
Liu C, Liang B, Li Z et al. · 2025 · LWT.
Adding fish oil (FO) to emulsified surimi gels enhances nutritional properties but hinders gel formation, posing a challenge to mitigate these adverse effects. In this study, sodium starch octenylsuccinate based-silver carp oil Pickering…
Randhawa S, Mukherjee T · 2025 · Journal of Food Composition and Analysis.
The research paper investigates how elemental copper and iron, affect the aging process of canola, coconut, groundnut, rice bran, soybean, and sunflower oils. Samples analysed biannually over two years indicate that the addition of copper,…
Borges CC, Alves da Silva W, de Sá Filho AS et al. · 2026 · International journal of sport nutrition and exercise metabolism
This study aimed to evaluate the effects of short-term oral L-arginine (ARG) supplementation on vascular parameters, nitric oxide (NO) concentration, and muscular performance during upper limb resistance exercise in healthy young men. A…
Fleming HA, Whines A, Whelehan P et al. · 2025 · Preprint
Central to survival is our ability to learn that the sensory properties of food are associated with metabolic interoceptive signals (e.g., changing blood glucose). These signals influence cognition and brain activity, shaping the hedonic…
de Alencar JN, Felicioni SP · 2025 · Journal of electrocardiology
Background Electrocardiographic (ECG) "left ventricular hypertrophy (LVH) criteria" are widely used as surrogates for increased LV mass but show limited sensitivity. We evaluated their diagnostic performance against cardiac magnetic…
Rhee SM, Cho CH, Kim M et al. · 2025 · Clinics in shoulder and elbow
Background This study evaluates the biomechanical effects of acellular dermal matrix (ADM) patch augmentation in a rotator cuff repair model and determines the effect of medial knot tying on time-zero stability. Methods A biomechanical…
Meau-Petit V, Mottez C, Bhojnagarwala B et al. · 2026 · Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Objectives Six-region lung ultrasound (LUS) scores show good predictive value for predicting surfactant need in preterm infants but rely on a fixed threshold, which may lead to misclassification near the cut-off and lack data-driven…
Sahu SA, Mishra JK, De M et al. · 2026 · GMS Interdisciplinary plastic and reconstructive surgery DGPW
Background Microvascular tissue transfer is the method of choice for oncological and trauma reconstruction. Successful free tissue transfer requires technical expertise and management of patients and surgery related factors. However,…
Krackow E, Rashed J, Thompson I · 2025 · The International journal of clinical and experimental hypnosis
Steven Jay Lynn was one of the most prolific clinical psychologists who made major contributions to the scientific literature in numerous areas, including in the area of hypnosis and memory. We review this work, limited to studies…