Negative / Null Result ReportOpen accessMedicine
Zainuddin MS, Pamidi N, Azman AS et al. · 2026 · Redox report : communications in free radical research
Alzheimer's disease (AD) is a major global neurodegenerative disorder associated with high morbidity and mortality, yet current treatments remain largely symptomatic and ineffective in halting neurodegeneration. Growing evidence links…
View details →DOI: 10.1080/13510002.2026.2677396 Negative / Null Result ReportMedicine
Fukui S, Sumiyoshi R, Koga T et al. · 2026 · Drug discoveries & therapeutics
Idiopathic multicentric Castleman disease (iMCD) is a rare lymphoproliferative disease characterized by systemic inflammation. Although IL-6 receptor blockade with tocilizumab is an established treatment, Janus kinase (JAK) inhibition may…
View details →DOI: 10.5582/ddt.2026.01000 Negative / Null Result ReportMedicine
Garabet W, Beckamp KH, Shabes P et al. · 2026 · VASA. Zeitschrift fur Gefasskrankheiten
Background: Supervised Exercise Therapy (SET) improves walking performance in patients with peripheral arterial disease (PAD) and intermittent claudication, yet implementation and adherence remain inconsistent. This study evaluated…
View details →DOI: 10.1024/0301-1526/a001280 Negative / Null Result ReportMedicine
Mobasseri M, Vahabie AH, Jafari G et al. · 2026 · Brain imaging and behavior
Behavioral contagion is defined as the tendency of individuals to conform with others' behavior after observing them. Despite the important role that behavioral contagion plays in societies, its brain mechanism is still not fully…
View details →DOI: 10.1007/s11682-026-01104-2 Negative / Null Result ReportMedicine
Ptak A, Stefańska M · 2026 · Journal of clinical medicine
Background: The objective of this study was to assess the tension of selected postural muscles during the jaw-sucking movement in four body positions (standing position, all-fours position, lying on front, lying on the side). Material and…
View details →DOI: 10.3390/jcm15041464 Negative / Null Result Report
Harding M, Case J, Knighton K et al. · 2026 · Preprint
Abstract Medical school has long been thought to have a potentially detrimental effect on the health of its students. We sought to understand if students experienced a decline in their cardiorespiratory physical fitness during their first…
View details →DOI: 10.21203/rs.3.rs-9762955/v1 Negative / Null Result ReportMedicine
Guo C, Geng A, Wang Q et al. · 2026 · Journal of integrative neuroscience
Background The cortex and cerebellum have a closely connected closed-loop circuit. Intermittent theta burst stimulation (iTBS) targeting the cerebellum has shown promise in improving balance function and inducing neuroplasticity. This…
View details →DOI: 10.31083/jin47653 Negative / Null Result ReportMedicine
Salimi Y, Namdarzadeh B, Aarani FD et al. · 2026 · Behavioural brain research
The gut-brain axis plays a key role in the bidirectional communication between the gastrointestinal system and the brain, with gut microbiota significantly influencing cognitive function. While synbiotic and probiotic interventions have…
View details →DOI: 10.1016/j.bbr.2026.116349 Negative / Null Result ReportMedicine
Sudhakar S, Mishra VK, Harikrishna S et al. · 2026 · Physical chemistry chemical physics : PCCP
Human PrimPol (hPrimPol) is the primase and polymerase enzyme involved in reinitiating DNA replication at stalled replication forks. The hPrimPol mutants are linked to multiple ophthalmoplegic conditions and mitochondriopathies. The WFYY…
View details →DOI: 10.1039/d6cp00786d Negative / Null Result ReportMedicine
Sanmartino F, Rashid-López R, López-Sosa F et al. · 2026 · International journal of neural systems
Resting-state eye conditions modulate cortical oscillations, but their impact on subthalamic nucleus (STN) and cortico-STN dynamics in Parkinson's disease (PD) remains poorly understood. Here, we characterized electrophysiological changes…
View details →DOI: 10.1142/s0129065726500310 Negative / Null Result ReportOpen accessMedicine
Mabkhot BA, Taha SEE, Kamel MH et al. · 2026 · BMC oral health
BACKGROUND: Subgingival crown margins have been linked to chronic gingival inflammation in pediatric patients. This clinical trial evaluated periodontal outcomes in first permanent molars that had undergone root canal therapy and were…
View details →DOI: 10.1186/s12903-026-08077-0 Negative / Null Result ReportMedicine
Koper M, Jaworska K, Kopacz W et al. · 2026 · Kidney & blood pressure research
Hypertension contributes to renal dysfunction, partly through dysregulation of the renin-angiotensin system (RAS). Betaine, an osmolyte that helps maintain medullary osmotic gradients, has demonstrated renoprotective effects in models of…
View details →DOI: 10.1159/000552883 Negative / Null Result ReportMedicine
Wiel É, Menu H, Roger F et al. · 2026 · Anaesthesia, critical care & pain medicine
Background Endotracheal Intubation (ETI) inserts an endotracheal tube (ETT) inside the human trachea to allow a proper mechanical ventilation of the lungs. Practitioners insert the ETT through the human vocal cords following a…
View details →DOI: 10.1016/j.accpm.2026.101878 Negative / Null Result ReportMedicine
Yuan Y, Gao Y, Moen H et al. · 2026 · NPJ digital medicine
Digital phenotyping leverages continuous data from smartphones and wearable devices for real-time mental health monitoring, offering opportunities for early detection and personalized care in mood disorders by enabling clinicians to…
View details →DOI: 10.1038/s41746-026-02883-0 Negative / Null Result ReportOpen accessMedicine
Montasser ZM, Montasser MA · 2026 · BMC oral health
Objective To review the available evidence on temporomandibular joint morphological changes after orthodontic treatment with clear aligners, as assessed using CBCT scans. Materials and methods This review sought randomized clinical trials,…
View details →DOI: 10.1186/s12903-026-08414-3 Negative / Null Result ReportMedicine
Singh Y, Lei Q, Dixit M et al. · 2026 · Medical care research and review : MCRR
Corporate employment of primary care physicians by hospitals and private equity-backed organizations has increased in recent years, raising concerns that the financial incentives of corporate employment will incentivize provision of…
View details →DOI: 10.1177/10775587261453724 Negative / Null Result ReportOpen accessMedicine
Karacaer C, Kaya G, Ergenc H et al. · 2026 · Pakistan journal of medical sciences
Objectives This study aimed to evaluate the prognostic significance of Cluster of Differentiation 4 (CD4+) and Cluster of Differentiation 8 (CD8+) T cell dynamics and cytokine profiles during the early stage of Coronavirus Disease 2019…
View details →DOI: 10.12669/pjms.42.5.15021 Negative / Null Result ReportMedicine
Abassi W, Ouerghi N, Feki O et al. · 2026 · Clinics (Sao Paulo, Brazil)
Objective Obesity is a major independent risk factor for chronic kidney disease. High-Intensity Interval Training (HIIT) is recognized as an interesting therapeutic strategy in managing obesity and related disorders. However, there is…
View details →DOI: 10.1016/j.clinsp.2026.100904 Negative / Null Result ReportMedicine
Oğuz F, Türk SK, Yavan MA · 2026 · Scientific reports
This controlled retrospective study aimed to evaluate the effects of maxillary protraction therapy on mandibular symphysis morphology. In this regard, 35 growing individuals with skeletal class III malocclusion due to maxillary…
View details →DOI: 10.1038/s41598-026-59387-w Negative / Null Result Report
Yang G, Zhu J, Xu J et al. · 2026 · Preprint
Abstract Background This study examined the effects of a 12-week Khon Kaen Qigong (KKQ) program on cerebellar-related motor coordination, gait/postural control, and simple reaction speed in older adults with mild cognitive impairment…
View details →DOI: 10.21203/rs.3.rs-9749508/v1 Negative / Null Result ReportMedicine
Dantsi F, Kypraiou A, Kouvelas N et al. · 2026 · Sports (Basel, Switzerland)
Most detraining research in swimming has focused on competitive athletes, whereas less is known about recreational university swimmers, a population commonly exposed to temporary interruptions in structured training. This study examined…
View details →DOI: 10.3390/sports14060246 Negative / Null Result ReportMedicine
Schuckit MA, Smith TL, Danko G et al. · 2026 · Alcohol, clinical & experimental research
Objectives The retrospective self-report of the effects of alcohol (SRE) questionnaire generates three scores reflecting drinking quantities required for effects: SRE-5 (first five times of drinking), SRE-3 (recent 3 months of drinking),…
View details →DOI: 10.1111/acer.70269 Negative / Null Result ReportOpen accessMedicine
Jambor T, Goc Z, Tokarova K et al. · 2025 · Physiological research
The growing popularity of microgreens is due to several health-promoting effects. Current evidence suggests a reduction in the risk of cardiovascular and neurodegenerative diseases, or anti-carcinogenic and anti-inflammatory effects.…
Negative / Null Result ReportMedicine
Puls HT, Lindberg DM, Noelke C et al. · 2026 · Academic pediatrics
Objective To determine whether community advantage moderated rates of hospital encounters for child physical abuse during the COVID-19 pandemic. Methods This was a population-based retrospective study of 12 states during 2019 to 2021. The…
View details →DOI: 10.1016/j.acap.2026.103300 Negative / Null Result Report
Worku KB, Bronstert A, Francke T et al. · 2026 · Preprint
The Upper Blue Nile Basin contributes about 60% of the Nile River’s annual streamflow but faces severe sediment-related challenges driven by intense monsoonal erosion and reservoir siltation. Accurate estimation of suspended sediment…
View details →DOI: 10.20944/preprints202606.0541.v1 Negative / Null Result ReportMedicine
Fuchs S, Majer M, Ma Y et al. · 2026 · Pflugers Archiv : European journal of physiology
Diabetic nephropathy (DN) is characterized by a decline in renal function resulting from hyperglycaemia and is often requiring dialysis or renal transplantation. Yet, the signalling events causing DN and the effective treatment options are…
View details →DOI: 10.1007/s00424-026-03190-z Negative / Null Result ReportMedicine
Noell SE, Colville EC, Marshall A et al. · 2026 · FEMS microbiology ecology
The Bratina Island meltwater ponds (McMurdo Ice Shelf, Antarctica) host complex microbial communities in the form of benthic microbial mats. These ponds are long-lasting but can experience significant alterations in physicochemistry on an…
View details →DOI: 10.1093/femsec/fiag069 Negative / Null Result ReportMedicine
Jahanian Najafabadi A, Rastegari A, Imani H et al. · 2026 · Acta psychologica
The plasticity of body representation in response to tool use is a dynamic process that evolves across the lifespan. Research has shown that tools can become integrated into the body representation, effectively being treated as extensions…
View details →DOI: 10.1016/j.actpsy.2026.106476 Negative / Null Result ReportMedicine
Chowdhury M, Bustamante AV · 2026 · Health affairs (Project Hope)
Lawfully present noncitizen immigrants face persistent coverage gaps due to federal restrictions on Medicaid eligibility, including the five-year bar under the 1996 Personal Responsibility and Work Opportunity Reconciliation Act, and…
View details →DOI: 10.1377/hlthaff.2025.01545 Negative / Null Result ReportMedicine
Yakasai AM, Maharaj SS, Danazumi MS · 2026 · American journal of physical medicine & rehabilitation
Objective This study evaluated the efficacy of endurance exercise on balance impairment and gait disturbance among individuals living with Human Immunodeficiency Virus (HIV)-related distal symmetrical polyneuropathy (DSPN). Design This was…
View details →DOI: 10.1097/phm.0000000000003073 