A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21733 results · page 492 of 725
Acierno J, Tedaldi E, Ginn J et al. · 2026 · Communications psychology
Social norms have a reliable and oftentimes strong influence on individual attitudes and behaviors across environmental and other domains. This influence has been theorized to differ by cultural tightness-the extent to which people adhere…
D'Agostini M, Vanden Bossche L, Burger AM et al. · 2025 · Psychophysiology
Transcutaneous auricular vagus nerve stimulation (taVNS) has been tested as a strategy to facilitate fear extinction learning based on the hypothesis that taVNS increases central noradrenergic activity. Four studies out of six found taVNS…
· 2025 · Nature
Neutrinos are the most abundant fundamental matter particles in the Universe and play a crucial part in particle physics and cosmology. Neutrino oscillation, discovered about 25 years ago, shows that the three known species mix with each…
Xiang Y, Xu L, Sun Y et al. · 2025 · Medicine
Mobile phone use has become ubiquitous in modern life, raising public concern over its potential effects on male reproductive health. While several observational studies have reported associations between prolonged phone use and decreased…
He J, Sabroso-Lasa S, Coscia C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background Observational studies consistently report reduced pancreatic ductal adenocarcinoma (PDAC) risk among individuals with atopic conditions (asthma and rhinitis); however, the underlying biological mechanism remains unclear. This…
Schleimer JP, Rencken CA, Wagenaar BH et al. · 2026 · JAMA network open
Importance Background checks aim to prevent illegal firearm transfers. Existing research has shown little evidence for the effect of point-of-sale comprehensive background check (CBC) policies on firearm-related violence at the state…
Nielsen SP, Mathiesen L, Moller P · 2024 · Preprint
not-yet-known not-yet-known not-yet-known unknown Abstract This review examines the association between early life exposure to phthalates in human males and Leydig cell endocrine function. A systematic search was performed in PubMed and…
Walda SAE, van Weerdenburg M, Bosman AMT · 2024 · Research in developmental disabilities
Background Poor decoding and spelling (literacy) skills have been associated with weak working memory. Aims The aim of this study was to elucidate the contribution of working memory to literacy progress in students with dyslexia. It has…
Bertoldi AD, Flores TR, Silveira MPT et al. · 2026 · Ciencia & saude coletiva
This study aimed to investigate the association between the use of antimicrobials during pregnancy and excess weight in children at ages three, 12, 24 and 48 months. Data of participants from the 2015 Pelotas (Brazil) Birth Cohort study…
Hiredesai AN, Martinez CJ, Hinckley NB et al. · 2026 · Cureus
Purpose Shear wave elastography (SWE) is a non-invasive technique for assessing median nerve (MN) stiffness in carpal tunnel syndrome (CTS). This study evaluated whether SWE measurements of the MN improve after corticosteroid injection…
Pater WJ, Buller LT, Ziemba-Davis M et al. · 2026 · Arthroplasty today
Background Tourniquet use in revision total knee arthroplasty (rTKA) enhances visualization and improves cement penetration. However, concerns exist about muscle injury, pain, wound complications, and venous thromboembolism (VTE). This…
El Alam A, Fleifel M, Nassani BM · 2026 · Cureus
Background Meal frequency takes a large focus when people enter a weight-loss program. Objective The primary aim of this study was to compare fat percentage and muscle percentage across three self-reported meal-frequency patterns,…
Wenzel M, Rowland Z · 2024 · Preprint
Research on emotion regulation (ER) has shifted from focusing on the static to the flexible use of ER strategies in response to environmental demands, emphasizing the importance of strategy-situation fit. Despite the growing theoretical…
Barker J, Sau A, Bajaj N et al. · 2024 · Preprint
Background Pulmonary vein isolation (PVI) is the mainstay of ablation for atrial fibrillation (AF). Adjunctive posterior wall isolation (PWI) has not demonstrated convincing additional benefit. To provide mechanistic underpinnings as to…
Lopez DS, Polychronopoulou E, Abdelgadir O et al. · 2025 · Cancers
Background/Objectives: Metformin is one of the most frequently used concomitant medications among prostate cancer (PCa) patients. However, the effects of metformin on all-cause and PCa-specific mortality among men diagnosed with…
Bateman SP, Wright K · 2024 · Preprint
Personality is regarded as stable over time, and thus measures of personality assume that personality traits are largely unaffected by one's state. However, several studies demonstrate that personality measurements can be biased by one's…
El-Enbaby H, Hollingsworth B, Maystadt JF et al. · 2024 · Economics and human biology
The relationship between poverty and mental health is complex. Conditional cash transfers are seen as an important policy tool in reducing poverty and fostering social protection. Evidence on the impact of cash transfers on mental health…
Kransberg J, Sjøli Bråthen AC, Falch ES et al. · 2026 · Imaging neuroscience (Cambridge, Mass.)
Grid cells in the human entorhinal cortex (EC) play a critical role in spatial navigation and memory. The EC is also one of the first regions affected by ageing and Alzheimer's disease. This pre-registered functional magnetic resonance…
Wenzel K, Thomas J, Carrano J et al. · 2025 · Drug and alcohol dependence reports
Substance use disorders (SUDs) including opioid use disorder (OUD) and alcohol use disorder (AUD) contribute to significant morbidity and mortality in the United States. Pharmacotherapy treatment, including extended-release naltrexone…
Liu X, Zhu Z, Chawes B et al. · 2026 · Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
Background Vitamin D may play a role in early lung development, yet epidemiologic evidence on its association with later asthma risk is mixed. We aimed to investigate the associations of neonatal 25-hydroxyvitamin D (25(OH)D) and vitamin…
Chatila ZK, Duggan MR, Silberberg E et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association
While a growing body of literature suggests a role for infections in Alzheimer's disease (AD), microbial contributions to AD remains a contentious topic, in part due to challenges in reconciling the positive evidence with studies reporting…
Helac A, Uchino BN · 2025 · Acta psychologica
General perceived social support is important because it is linked to significant health outcomes. Most research examining perceived social support and health behaviors has not formally modeled the influence of interdependence in a dyad.…
Gao S, Gross AL, Aksman LM et al. · 2026 · Journal of Alzheimer's disease : JAD
BackgroundPlasma neurodegenerative biomarkers are a potential low-cost tool for studying Alzheimer's disease and dementia in population-based research, especially in low- and middle-income countries. However, their associations with…
Atkinson A, Marschall J, Burnham JP · 2025 · Antimicrobial resistance and infection control
Background Air changes per hour (ACH) in operating rooms (ORs) are energy intensive, and optimal air change settings are not known. Objectives We sought to explore whether there is a relationship between surgical site infections (SSIs)…
Perales-Puchalt J, Yang FM, Townley R · 2025 · Alzheimer disease and associated disorders
We tested the efficacy of docosahexaenoic acid (DHA) supplementation on aggressive behavior among people with dementia. We used secondary data from a randomized, double-blind, placebo-controlled trial. Analyses included 402 individuals…
Sheng Y, Han Y, Xue Y · 2026 · Medicine
Beta-blockers are recommended for post-myocardial infarction (MI) care, but their long-term impact on all-cause mortality in real-world settings remains unclear. This study investigates the association using propensity score methods in a…
Watkins K, Ladabaum U, Olsen E et al. · 2024 · iGIE : innovation, investigation and insights
Background and aims The progress of artificial intelligence (AI) in endoscopy is at a crossroads. The positive results of randomized controlled trials of computer-aided detection (CADe) have not been replicated in multiple pragmatic CADe…
Kusztor A, Mulay N, Yamada M et al. · 2025 · Neuroscience of consciousness
During an acute episode of depersonalization/derealization (DP/DR), people report a complex and idiosyncratic change in their perceptual experience. Specifically, derealisation describes the experience of detachment from the external world…
Raut U · 2023 · Preprint
The formation of mini black holes is now considered to be an inescapable consequence of TeV scale particle collision scenarios in extra-dimensional/ADD models. Furthermore, such mini black holes have been predicted to be produced at…
Beaver JN, Nicodemus MM, Spalding IR et al. · 2025 · eNeuro
Mice offer a wealth of opportunities for investigating brain circuits regulating multiple behaviors, largely due to their genetic tractability. Social behaviors are translationally relevant, considering both mice and humans are highly…