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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20261 results in Negative / Null Result Report · page 480 of 676

Negative / Null Result ReportMedicine

Concomitant cholecystectomy did not significantly reduce the risk of subsequent biliary events and malignancy in treating gallstone ileus.

Su YS, Liu HY, Chen CY et al. · 2026 · Surgical endoscopy

Background This nationwide cohort study compared long-term subsequent benign biliary events and biliary tract malignancy in patients with gallstone ileus treated with or without concomitant cholecystectomy. Methods This retrospective…

View details →DOI: 10.1007/s00464-025-12536-0
Negative / Null Result ReportMedicine

Management of the Condyle in Posterior Mandibular Reconstruction: Major Clinical and Patient-Reported Outcomes.

Coleman-Belin JC, Zhang KK, Cohen Z et al. · 2026 · Journal of surgical oncology

Background and objectives Tumor involvement of the posterior mandible often requires resection of the mandibular condyle and associated soft tissue. This study explores clinical and patient-reported outcomes (PROs) associated with condyle…

View details →DOI: 10.1002/jso.70182
Negative / Null Result ReportMedicine

Investigating compensatory adjustments induced by rhythmic auditory stimulation for changes in temporal gait symmetry in lower-limb prosthetic users.

Gouda A, Arshad MZ, Andrysek J · 2026 · PloS one

Gait training is an important part of rehabilitation for prosthetic users, improving mobility and long-term health outcomes. This study investigated the effects of rhythmic auditory stimulation (RAS) on gait symmetry and overall movement…

View details →DOI: 10.1371/journal.pone.0351930
Negative / Null Result ReportMedicine

The effect of eggshell translucency on egg weight, embryonic development, hatching traits, chick quality, post-hatch growth, carcass, and organ traits in Ross 308 fast growing broiler strains at 7 days of age.

Abdallah N, Kursun K, Baylan M · 2026 · Tropical animal health and production

This study investigated the effect of eggshell translucency on egg weight, embryonic development, hatching traits, chick quality, post-hatch growth, carcass, and organ traits at 7 days of age in broiler chickens. A total of 300 hatching…

View details →DOI: 10.1007/s11250-026-04899-w
Negative / Null Result ReportOpen accessMedicine

[Corrigendum] Associations between Huwe1 and autophagy in rat cerebral neuron oxygen‑glucose deprivation and reperfusion injury.

He GQ, Chen Y, Liao HJ et al. · 2026 · Molecular medicine reports

Following the publication of the above article, the authors have contacted the Editor to explain that, regarding the immunofluorescence experiments shown in Fig. 3 on p. 5089, the data correctly shown in Fig. 3I (for the 'V‑ctrl+DMSO+R 24…

View details →DOI: 10.3892/mmr.2026.13833
Negative / Null Result Report

Patterns of Typical and Atypical Age-related Brainstem Volume losses

Mueller S, Mackin R · 2026 · Preprint

Background The brainstem and its different sub-systems control essential functions such as motor agility etc. that worsen with age. The purpose of this study was: 1. To assess the impact of age-related volume loss within three brainstem…

View details →DOI: 10.64898/2026.05.21.726989
Negative / Null Result ReportMedicine

Source of lateralization in reverse total shoulder arthroplasty matters: a comparison of glenoid and humeral lateralization on rotator cuff biomechanics.

Brusalis CM, Glenday J, Fu MC et al. · 2026 · Journal of shoulder and elbow surgery

Background Compared with the traditional Grammont design, modern reverse total shoulder arthroplasty (rTSA) implant designs often introduce lateralization of the glenoid and/or humeral components. This study aimed to evaluate the impact of…

View details →DOI: 10.1016/j.jse.2026.02.021
Negative / Null Result ReportMedicine

How mathematics anxiety relates to mathematical ability in AI agent-supported instruction: the moderating role of executive function.

Lin G, Tang B, Niu Y et al. · 2026 · BMC psychology

Mathematical ability is widely recognized as a core indicator of students' cognitive development and academic achievement. However, in classroom environments where artificial intelligence (AI)-supported instruction is increasingly…

View details →DOI: 10.1186/s40359-026-04994-5
Negative / Null Result ReportMedicine

Does the Combination of Calcium Hydroxide and Chlorhexidine Gel Affect Dentinal Tubule Penetration of Epoxy Resin and Tricalcium Silicate-Based Sealers?

Baran EK, Oncu A, Celikten B · 2026 · Australian endodontic journal : the journal of the Australian Society of Endodontology Inc

This study evaluated effect of calcium hydroxide (CH) medicaments prepared with distilled water, glycerin and chlorhexidine (CHX) gel on dentinal tubule penetration of epoxy resin- and tricalcium silicate-based sealers using confocal laser…

View details →DOI: 10.1111/aej.70093
Negative / Null Result Report

Analytical Discordance Between Point-of-Care Troponin Assays and a Central Laboratory High-Sensitivity Assay in a Sri Lankan Hospital Setting: Implications for Implementation

Fernando K, Fernando N, Jayasekara D et al. · 2026 · Preprint

Point-of-care testing (POCT) for cardiac troponin is increasingly used to support rapid clinical decision-making, particularly in resource-limited settings. However, while many central laboratories, including those in Sri Lanka, now use…

View details →DOI: 10.20944/preprints202605.1183.v1
Negative / Null Result ReportOpen accessMedicine

Preliminary examination of disgust learning as a potential OCD endophenotype.

Jessup SC, Zald DH, Olatunji BO · 2026 · Journal of affective disorders

Endophenotypes (intermediate phenotypes) are traits hypothesized to represent genetic risk for disorders such as OCD. However, it is unclear if disgust conditioning abnormalities may function as an OCD endophenotype. The present study…

View details →DOI: 10.1016/j.jad.2026.121619
Negative / Null Result ReportMedicine

Design and Preliminary Evaluation of a Hand-Held Surgical Robot for Enhanced Intuitive Control in Laparoscopy.

Kong K, Qiang Z, Yang Y et al. · 2026 · The international journal of medical robotics + computer assisted surgery : MRCAS

Background Surgical robots offer improved precision and stability for laparoscopy; nevertheless, their limited portability and high cost impede broader clinical applications. Methods This paper proposes a hand-held surgical robot with an…

View details →DOI: 10.1002/rcs.70176
Negative / Null Result ReportMedicine

EEG activities and connectivities associated with surtitle presentation during live opera viewing: an exploratory analysis of cognitive absorption.

Boasen J, Giroux F, Duchesneau MO et al. · 2026 · Scientific reports

Characterizing brain activities underlying text availability in an ecologically valid context and identifying whether aspects of these activities are influenced by one's state of cognitive absorption (CA) are important yet unexplored lines…

View details →DOI: 10.1038/s41598-026-56620-4
Negative / Null Result Report

Cusp Overlap Versus Standard Three-Cusp Technique for Self-Expanding Transcatheter Aortic Valves – A Single Center Experience

Ispas A, Brunet D, Saadi R et al. · 2026 · Preprint

Background: Conduction disturbances and the subsequent need for permanent pacemaker implantation (PPMI) remain a major limitation of transcatheter aortic valve replacement (TAVR) with self-expanding transcatheter heart valves (SE-THVs).…

View details →DOI: 10.20944/preprints202606.0545.v1
Negative / Null Result ReportMedicine

Effects of filtered vs. unfiltered TikTok videos on mood, body and facial satisfaction, and cosmetic surgery interest.

Harriger JA, Brown SA, Chung HG et al. · 2026 · Body image

This study investigated the effects of exposure to unfiltered vs. filtered idealized TikTok videos in a sample of 299 adult women, ages 18-83-years-old. Participants were randomly assigned to view idealized unfiltered, idealized filtered,…

View details →DOI: 10.1016/j.bodyim.2026.102030
Negative / Null Result ReportMedicine

Feasibility, safety and outcomes of contrast-free cardiac resynchronisation therapy device implantation: a retrospective cohort comparison.

Friedrich L, Walgenbach M, O Connor M et al. · 2026 · Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

BACKGROUND: Left ventricular lead (LVL) implantation can be challenging in Cardiac Resynchronization Therapy (CRT). Therefore, contrast is commonly used to visualize the coronary venous system. However, contrast use is correlated with…

View details →DOI: 10.1007/s10840-026-02283-0
Negative / Null Result ReportMedicine

Sleep Quality in Later Life: How Does It Affect Driving Safety?

Barrett AE, Soulie B, Mimbs H et al. · 2026 · International journal of aging & human development

Drowsy driving is a major cause of motor vehicle injuries and fatalities, yet little is known about its impact on older adults. This group may face heightened risk due to age-related sleep issues. Using survey data from 3,411 Floridians…

View details →DOI: 10.1177/00914150261445628
Negative / Null Result ReportMedicine

Carboplatin with or without nivolumab in metastatic triple-negative breast cancer: a randomized phase II trial.

Garrido-Castro AC, Graham N, Li KX et al. · 2026 · Nature communications

This multi-institutional randomized phase II clinical trial (NCT03414684) investigated the efficacy and safety of carboplatin plus nivolumab compared to carboplatin in metastatic triple-negative breast cancer (mTNBC). The primary endpoint…

View details →DOI: 10.1038/s41467-026-73085-1
Negative / Null Result ReportMedicine

Cardiovascular and limb outcomes with SGLT2 inhibitors in patients with diabetes following peripheral endovascular therapy.

Tomoi Y, Takahara M, Soga Y et al. · 2026 · Journal of cardiology

Background Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) are recommended for patients with diabetes mellitus (DM) and peripheral artery disease (PAD), their effects on limb-related outcomes remain uncertain, and their use…

View details →DOI: 10.1016/j.jjcc.2026.06.012
Negative / Null Result ReportMedicine

Beyond core symptoms: the association between caregiver anxiety and ADHD symptom severity and metacognitive awareness in children.

Karaca BŞ, Alşen Güney S · 2026 · Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

This study examined the association between caregiver anxiety, ADHD symptom severity, and metacognitive awareness in children with attention-deficit/hyperactivity disorder (ADHD), and evaluated whether metacognitive awareness mediates the…

View details →DOI: 10.1080/09297049.2026.2681661
Negative / Null Result ReportMedicine

The effect of a structured injury prevention program on injury severity and type in elite Adolescent and Young Adult Taekwondo athletes.

Kim HC, Park KJ · 2026 · Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine

Objectives To evaluate the effect of the 'Get Set-Train Smarter' warm-up program on injury incidence, type, and severity in elite Adolescent and Young Adult (AYA) Taekwondo athletes. Design Cluster-randomized controlled trial. Setting…

View details →DOI: 10.1016/j.ptsp.2026.101943