e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19878 results in Negative / Null Result Report · page 467 of 663

Negative / Null Result ReportOpen accessMedicine

Impact of superior mesenteric artery (SMA) adherent tissue in the context of pancreatic head resections- an observational study.

Azizian A, Bernhardt M, Rühlmann F et al. · 2026 · BMC cancer

Background Resection of the periadventitial neurolymphatic tissue around the superior mesenteric artery (SMA) is considered a crucial component of oncologically complete resection in pancreatic head and corpus carcinomas. However, a…

View details →DOI: 10.1186/s12885-026-16278-7
Negative / Null Result ReportOpen accessMedicine

Electrical muscle stimulation towards self-physiotherapy on myofascial pain syndrome.

Churproong S, Metcalfe B, Mcguigan P et al. · 2026 · Frontiers in rehabilitation sciences

Background Myofascial trigger points (MTrPs) are the cause of pain from myofascial pain syndrome (MPS), frequently in the trapezius muscle (TM). Working adults often avoid treatment due to the need for therapist assistance and limited…

View details →DOI: 10.3389/fresc.2026.1817369
Negative / Null Result ReportMedicine

Performance of large language models and clinical decision support in perioperative management of oral anticoagulants.

Çalışkan MU, Sarıbaş H, Keskin G et al. · 2026 · International journal of medical informatics

Background Perioperative anticoagulant management is critical because of the competing risks of ischemia and bleeding. Large language models (LLMs) and clinical decision support (CDS) have shown substantial advances and are increasingly…

View details →DOI: 10.1016/j.ijmedinf.2026.106456
Negative / Null Result ReportMedicine

Comparison of 3D extraoral scanning of artex articulator scan vs scan fixator in a fully edentulous arch - in-vitro study.

Alkhallagi TS, Alshammari BK, Babeer WA et al. · 2026 · BMC oral health

Background This in vitro study compared the precision of articulator-based scanning and scan fixator-based scanning in completely edentulous arches with implant scan bodies. Materials and methods Upper and lower master casts were…

View details →DOI: 10.1186/s12903-026-08476-3
Negative / Null Result ReportOpen accessMedicine

Platelet-rich plasma versus granulocyte colony-stimulating factor in addressing recurrent implantation failure: A randomized, double-blind clinical trial.

Tehrani HG, Mostajeran E, Dehghani-Mohammadabadi R et al. · 2026 · Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Background The aim of the study is to evaluate the effect of platelet-rich plasma (PRP) versus granulocyte colony-stimulating factor in addressing recurrent implantation failure. Materials and methods Fifty patients were randomly assigned…

View details →DOI: 10.4103/jrms.jrms_736_23
Negative / Null Result ReportOpen accessMedicine

The impact of narcissistic personality traits on social media interaction and body image: individual and team athletes.

Kiliç K, Sezer BS, Aydinli İ et al. · 2026 · Frontiers in psychology

Introduction The aim of this study is to examine the effect of narcissistic personality traits on body image through social media interaction and to comparatively evaluate these relationships in the context of athletes engaged in…

View details →DOI: 10.3389/fpsyg.2026.1848790
Negative / Null Result ReportOpen accessMedicine

Outcome analysis of conservative treatment of a distal radius fracture with OPTIVOhand orthosis versus plaster cast: a randomized controlled trial.

Friederich M, Brunner J, Kirsch E et al. · 2026 · BMC musculoskeletal disorders

Background Distal radius fractures (DRF) are often immobilized using a conventional plaster cast although orthoses offer a time- and resource-saving alternative. This prospective randomized study compared the conservative DRF treatment…

View details →DOI: 10.1186/s12891-026-09585-4
Negative / Null Result ReportOpen accessMedicine

Association of 25(OH)D status with calcium metabolism, inflammation, and thyroid autoimmunity in patients with type 2 diabetes mellitus.

Lv N, Xiang J, Kuang J et al. · 2026 · Frontiers in endocrinology

Introduction 25-hydroxyvitamin D [25(OH)D] deficiency is highly prevalent in type 2 diabetes mellitus (T2DM) and may contribute to immune and metabolic dysfunction. This study aimed to investigate the clinical associations of serum 25(OH)D…

View details →DOI: 10.3389/fendo.2026.1867755
Negative / Null Result ReportOpen accessMedicine

Depression, anxiety, and mental state in patients with early-stage dementia: comparison of reminiscence therapy and cognitive stimulation therapy.

Demir ZG, Doğan IA, Keskin R et al. · 2026 · Dementia & neuropsychologia

Psychosocial interventions may differentially target affective and cognitive symptoms in mild dementia, yet comparative evidence in long-term care is limited. Objective To compare the effects of Reminiscence Therapy (RT) and Cognitive…

View details →DOI: 10.1590/1980-5764-dn-2025-0354
Negative / Null Result ReportOpen accessMedicine

Antimicrobial resistance phenotypes of E. coli from livestock and wildlife in Wyoming, U.S.A.

Bowers O, Killion HJ, Kuhlman K et al. · 2026 · BMC veterinary research

BACKGROUND: This study measured phenotypic resistance of enteric Escherichia coli (E. coli) obtained from livestock and wildlife across agricultural districts within Wyoming, U.S.A., to antimicrobials used in the cattle industry. It is the…

View details →DOI: 10.1186/s12917-026-05386-y
Negative / Null Result ReportOpen accessMedicine

KIF23 regulates cytoskeleton dynamics for cytokinesis and mitochondrial function during oocyte meiosis.

Zou YJ, Zhang KH, Lu PS et al. · 2026 · Cell communication and signaling : CCS

Cytoskeleton dynamics ensure multiple cellular progression during oocyte meiosis, which is critical for successful fertilization and early embryo development. KIF23, a member of the kinesin-6 superfamily, mediates intracellular transport…

View details →DOI: 10.1186/s12964-026-02906-z
Negative / Null Result ReportOpen accessMedicine

Effects of Ropivacaine-Based Thoracic Paravertebral Block versus Erector Spinae Plane Block on Quality of Recovery in Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial.

Shi S, Liang Y, Liu T et al. · 2026 · Drug design, development and therapy

Background Colorectal cancer remains a leading cause of cancer-related mortality worldwide. Postoperative pain can impair recovery. Thoracic paravertebral block (TPVB) and erector spinae plane block (ESPB) are regional analgesic techniques…

View details →DOI: 10.2147/dddt.s581084
Negative / Null Result ReportOpen accessMedicine

Functional data analysis of lower-limb joint kinematics during badminton lunges under fatigue.

Fang Y, Zhang X, Sun Y et al. · 2026 · Frontiers in bioengineering and biotechnology

Objective This study applied Functional Data Analysis (FDA) to investigate the effects of fatigue on lower-limb joint kinematics during badminton lunges. Methods Seventeen elite male badminton players executed both forward and 45° sideways…

View details →DOI: 10.3389/fbioe.2026.1741767
Negative / Null Result ReportMedicine

Evaluation of radiopacity in preheated fissure sealants: an in-vitro study.

Aydın Çetin EZ, Özmen B, Yılmaz B · 2026 · Oral radiology

OBJECTIVES: The use of preheated resin-containing materials is of increasing interest in contemporary dentistry. This study aimed to determine the effect of preheating on the radiopacity values of various fissure sealants. METHODS: In this…

View details →DOI: 10.1007/s11282-026-00919-5
Negative / Null Result ReportMedicine

High Abdominal Fat Deposition was Regulated by Abdominal Fatty Acid Synthesis Related Genes and Reduced Reproduction in Late Stage of Chinese Indigenous Wannan Yellow Chicken.

Yu H, Wu L, Wang H et al. · 2026 · Animal bioscience

Objective Compared with commercial laying hens, indigenous chicken breeds generally exhibit lower reproductive performance. This study aims to elucidate the impact of abdominal fat deposition on the reproductive performance of indigenous…

View details →DOI: 10.5713/ab.250869
Negative / Null Result ReportMedicine

Healing Integrity Determines Meniscal Extrusion After Isolated Medial Meniscus Posterior Root Repair in Knees With No Lower Limb Malalignment.

Kim JS, Hwang UJ, Woo CW et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

Purpose To investigate changes in meniscal extrusion and meniscal healing status following root repair, and the relationship between meniscal extrusion and healing conditions. Methods Patients who underwent isolated root repair between…

View details →DOI: 10.1002/arj.70337
Negative / Null Result ReportOpen accessMedicine

Evaluating poultry by-product meal, tomato pomace, and azolla with or without Natuzyme supplementation as sustainable alternatives to fish meal for Nile tilapia (Oreochromis niloticus).

Kamel AM, Mahmoud MM, Ibrahim MT et al. · 2026 · Tropical animal health and production

Several studies have predicted that developing countries will be unable to afford fish meal as a primary aquafeed protein source in the future. This experiment evaluated the effect of replacing fish meal (FM) with poultry by-product meal…

View details →DOI: 10.1007/s11250-026-05001-0
Negative / Null Result Report

Body Mass Index and Outcomes in HR+/HER2−Metastatic Breast Cancer Treated with Palbociclib: Insights from a National Real-World Study

Badau LM, Epure P, Margan M et al. · 2026 · Preprint

Background: /Objectives: The prognostic and predictive role of BMI in patients with HR+/HER2– MBC remains controversial, particularly in the era of CDK4/6 inhibitors. This study aimed to evaluate the association between baseline BMI and…

View details →DOI: 10.20944/preprints202604.1156.v1
Negative / Null Result ReportOpen accessMedicine

Monitoring the Adverse Implications of Coronavirus 2019-induced Pulmonary Complications on Patients' Respiratory Capacity and Physical Abilities with Moderate and Severe Signs during Interval Follow-up.

Aali F, Habibi Z, Aali F et al. · 2026 · Journal of medical signals and sensors

Background The respiratory system of individuals with coronavirus 2019 (COVID-19) experiences significant strain due to the body's immunological response and inflammation, leading to organ failure. Over time, patients have improvement in…

View details →DOI: 10.4103/jmss.jmss_15_25
Negative / Null Result ReportOpen accessMedicine

Endometrial HOXA-10, HOXA-11, ß-1 integrin, ECM-1, FAK, and CD44 immunohistochemical expressions in endometriosis-related recurrent IVF failure: a retrospective case-control study.

Toruk EŞ, Kaplan EA, Sarıbaş GS et al. · 2026 · Journal of ovarian research

BACKGROUND: Endometriosis is a common cause of infertility and is frequently associated with recurrent implantation failure in assisted reproductive technologies. Impaired endometrial receptivity, mediated by altered transcription factors,…

View details →DOI: 10.1186/s13048-026-02072-3
Negative / Null Result ReportOpen accessMedicine

Efficacy of Normobaric High-Flow Oxygen Therapy Combined with Low Molecular Weight Heparin in the Management of Fetal Growth Restriction: A Prospective Cohort Study.

He M, Zhao K, Wei Q et al. · 2026 · International journal of women's health

Objective This study investigated the clinical efficacy of adding normobaric high-flow oxygen therapy (NHFOT) to low molecular weight heparin (LMWH) and standard supportive care for the management of the present FGR cohort, idiopathic…

View details →DOI: 10.2147/ijwh.s574440
Negative / Null Result ReportMedicine

Outcomes of Patients With Reduced Left Ventricular Function Undergoing Left Atrial Appendage Occlusion.

Higgins AY, Huang CY, Zimmerman S et al. · 2026 · JACC. Clinical electrophysiology

Background Transcatheter left atrial appendage occlusion (LAAO) is an alternative treatment to prevent stroke in patients with atrial fibrillation. Patients with reduced left ventricular ejection fraction (LVEF) represent a particularly…

View details →DOI: 10.1016/j.jacep.2026.04.004
Negative / Null Result ReportMedicine

Single antiplatelet therapy vs oral anticoagulation monotherapy in patients with atrial fibrillation and coronary artery disease after successful catheter ablation: A target trial emulation.

Li F, Zhao Y, Peng X et al. · 2026 · Heart rhythm

Background The optimal long-term antithrombotic strategy in patients with atrial fibrillation (AF) and coronary artery disease (CAD) after successful catheter ablation (CA) remains uncertain. Objective This study aimed to compare the…

View details →DOI: 10.1016/j.hrthm.2026.05.027