Negative / Null Result ReportMedicine
Savaş EM, Bozkurt HH, Kemer NI et al. · 2026 · Leukemia research
Management of relapsed or refractory acute leukemia remains challenging, as allogeneic transplantation is the only curative option. Although targeted therapies are increasingly incorporated as bridge-to-transplant strategies in both AML…
View details →DOI: 10.1016/j.leukres.2026.108271 Negative / Null Result ReportMedicine
Pei LC, Wang T, Guo YJ et al. · 2026 · BMC pregnancy and childbirth
Background To evaluate the association between triple therapy (hydroxychloroquine sulfate, aspirin, and enoxaparin sodium) and pregnancy outcomes in patients with undifferentiated connective tissue disease (UCTD)-related recurrent…
View details →DOI: 10.1186/s12884-026-09337-1 Negative / Null Result ReportMedicine
Karunainathan MG, Lee C, Zohalinejad KD et al. · 2026 · Acta ophthalmologica
Purpose To evaluate real-world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age-related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals,…
View details →DOI: 10.1111/aos.70160 Negative / Null Result ReportMedicine
London KS, Cherney A, Neupane S et al. · 2026 · The American journal of emergency medicine
Background Non-trauma center (NTC) emergency departments (EDs) play regular but underappreciated roles in the management of severely injured patients, yet many lack formal protocols to guide care. We describe the implementation and…
View details →DOI: 10.1016/j.ajem.2026.05.032 Negative / Null Result ReportMedicine
Shirane K, Kitagawa N, Morishima R et al. · 2026 · Journal of pediatric surgery
Background Pulmonary metastasectomy can improve the survival of children with pulmonary metastases from solid tumors. However, preoperative imaging often suggests chest wall and/or mediastinal invasion, raising concerns about…
View details →DOI: 10.1016/j.jpedsurg.2026.163183 Negative / Null Result ReportOpen accessMedicine
Teng NMY, Vijayakumar B, Smith DJF et al. · 2026 · Access microbiology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was a global pandemic where infected individuals experienced mild or severe disease. Unfortunately, some patients who experienced severe disease also had lasting abnormalities.…
View details →DOI: 10.1099/acmi.0.001103.v3 Negative / Null Result ReportMedicine
Gándara-Mireles JA, Reyes Espinoza EA, Loera-Castañeda V et al. · 2026 · Current issues in molecular biology
Doxorubicin (Dox) is a cornerstone in the treatment of pediatric acute lymphoblastic leukemia (ALL), but its use is limited by dose-dependent cardiotoxicity. Oxidative stress, arising from mitochondrial dysfunction, enzymatic generation of…
View details →DOI: 10.3390/cimb48060577 Negative / Null Result ReportOpen accessMedicine
Szczupak M, Kobak J, Krupa-Nurcek S · 2026 · Frontiers in public health
Introduction Shift work is a recognized occupational risk factor for sleep disturbances, particularly among healthcare professionals. Nurses are especially vulnerable due to irregular work schedules, night duties, and the high physical and…
View details →DOI: 10.3389/fpubh.2026.1848179 Negative / Null Result ReportMedicine
Zhang Q, Yang T, Li L et al. · 2026 · Neurosurgical review
Chronic internal carotid artery occlusion (CICAO) is a significant cause of ischemic cerebrovascular events, with an annual stroke risk of up to 20%. Although the long-term efficacy of hybrid surgical revascularization (HSR) versus…
View details →DOI: 10.1007/s10143-026-04337-3 Negative / Null Result ReportMedicine
Aslan T, AlShamrani M, Buck B et al. · 2026 · Stroke and vascular neurology
Background Stroke rates rise steeply with age but data on tenecteplase in patients ≥80 years remain limited. This post-hoc analysis of the AcT trial compared tenecteplase with alteplase in this population. Methods The analysis included all…
View details →DOI: 10.1136/svn-2025-005030 Negative / Null Result Report
Peng M, Yuan Z, Lu Y et al. · 2026 · Preprint
Abstract Objective This study aims to investigate the effects of sleep disorders and cardiovascular disease comorbidity on the decade-long trajectory of memory function in middle-aged and elderly populations, thereby offering a scientific…
View details →DOI: 10.21203/rs.3.rs-9623506/v1 Negative / Null Result ReportMedicine
Khan RB, Hanzlik E, Deokumar S et al. · 2026 · Pediatric blood & cancer
Background Hodgkin lymphoma is the most common cancer in adolescence and is treated with chemotherapy and/or radiation therapy. Little is known about neurologic symptoms, signs, and morbidity in long-term survivors of childhood Hodgkin…
View details →DOI: 10.1002/1545-5017.70398 Negative / Null Result ReportMedicine
Qureshi S, Qureshi MA, Zehra SM et al. · 2026 · BMC cancer
Background Progastricsin/Pepsinogen C (PGC) is an aspartyl endoprotease predominantly expressed by gastric fundic and chief cells, with additional expression reported in select extragastric tissues. While increased PGC expression has been…
View details →DOI: 10.1186/s12885-026-16133-9 Negative / Null Result ReportMedicine
Wang S, Miao J, Tang F et al. · 2026 · BMC cardiovascular disorders
Background The recurrence rate after ablation for atrial fibrillation (AF) remains high, and the predictive performance of existing predictors is limited. Left atrial dysfunction plays a key role in the occurrence and progression of AF.…
View details →DOI: 10.1186/s12872-026-06131-x Negative / Null Result ReportMedicine
Banerjee R, Kuruvilla C, Vega GL et al. · 2026 · The American journal of cardiology
While triglyceride-rich lipoproteins and small dense low-density lipoprotein (sdLDL) are associated with accelerated coronary atherosclerosis, their relationship with peripheral artery disease (PAD) is less clear. Fifty-five male subjects…
View details →DOI: 10.1016/j.amjcard.2026.04.040 Negative / Null Result ReportMedicine
Pyne AL, Uchida AM, Carlson M et al. · 2026 · Esophagus : official journal of the Japan Esophageal Society
Background Eosinophilic esophagitis (EoE) shares several risk factors with other autoimmune diseases, but population-based studies in this field are limited. Methods Using the Swedish nationwide histopathology cohort Epidemiology…
View details →DOI: 10.1007/s10388-026-01212-4 Negative / Null Result ReportOpen accessMedicine
Kikumoto T, Kobayashi M, Hori S et al. · 2026 · International journal of sports physical therapy
The Functional Movement Screen™ (FMS™) is widely used to evaluate movement quality and attempt to identify athletes at risk of injury. However, the predictive value of the total score is inconsistent, and it remains unclear whether…
View details →DOI: 10.26603/001c.162342 Negative / Null Result ReportMedicine
Wang D, Dong X, Feng T · 2026 · Scientific reports
Brainstem auditory evoked potentials (BAEP) provide an objective assessment of brainstem functional integrity. However, their characteristic profiles and clinical significance in patients with prolonged disorders of consciousness (pDOC)…
View details →DOI: 10.1038/s41598-026-50050-y Negative / Null Result ReportMedicine
Resnick E, Travers C, Griffin R et al. · 2026 · Pediatric nephrology (Berlin, Germany)
Background Extremely low gestational age neonates (ELGANs) remain at high risk for morbidity and mortality. Acute kidney injury (AKI) is increasingly recognized, but data in the most immature neonates, especially those born at 22-23 weeks,…
View details →DOI: 10.1007/s00467-026-07214-9 Negative / Null Result ReportMedicine
Yılmaz U, Buzdağlı Y, Bilgin S et al. · 2026 · Journal of strength and conditioning research
Abstract Yılmaz, U, Buzdağlı, Y, Bilgin, S, Sepil, Y, Ozan, M, Bağaçlı, UH, Şıktar, E, Baygutalp, F, and Kılıç Baygutalp, N. Multidimensional physiologic adaptations to a 14-day detraining period in elite powerlifters: Neuromuscular,…
View details →DOI: 10.1519/jsc.0000000000005487 Negative / Null Result ReportOpen accessAnimal culture
Israel Lerma-Reyes, German D. Mendoza-Martínez, Rolado Rojo-Rubio et al. · 2018 · Asian-Australasian Journal of Animal Sciences
Objective This experiment was designed to evaluate the effect of supplementation with soybean or canola oil on milk production and the composition of long chain fatty acids as well as weight changes in the goats and their kids. Methods Thirty nine mulitparous crossed Alpine×Nubian goats (initial body weight [BW] 43.5±1.7 kg) from the day of parturition were assigned to the treatments: grazing control (n = 15); grazing plus 20 mL/goat/d of supplemental soybean oil (n = 12); and grazing plus 20 mL/goat/d of supplemental canola oil (n = 12) from November 26, 2014 to March 7, 2015. The planned con
View details →DOI: 10.5713/ajas.17.0058 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Yan Meng, Ming-xue Zhou, Chun-bo Wu et al. · 2023 · BMC Nephrology
Abstract Aim To determine whether continuous venovenous hemodiafiltration (CVVHDF) plus standard medical therapy (SMT) vs. SMT alone prevents rhabdomyolysis (RM)-induced acute kidney injury (AKI) and analyze the related health economics. Methods This retrospective cohort study involved 9 RM patients without AKI, coronary heart disease, or chronic kidney disease treated with CVVHDF plus SMT (CVVHDF + SMT group). Nine matched RM patients without AKI treated with SMT only served as controls (SMT group). Baseline characteristics, biochemical indexes, renal survival data, and health economic data w
View details →DOI: 10.1186/s12882-023-03242-x Negative / Null Result ReportOpen accessAnimal culture
P.P. Porto, E.O.S. Saliba, L.C. Gonçalves et al. · 2006 · Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Ensilaram-se três genótipos de girassol (M734, Rumbosol 91 e variedade V2000), enriquecidos no material original com: 0,5% de uréia (U); 0,5% de carbonato de cálcio (CC); 0,5% de uréia mais 0,5% de carbonato de cálcio (U+CC); inoculante bacteriano comercial (IB) comercial e sem aditivo que serviu como silagem testemunha (T). Foram utilizados silos de laboratório de PVC, abertos com 1, 3, 5, 7, 14, 28 e 56 dias de ensilados, sendo determinados fibra em detergente neutro (FDN), fibra em detergente ácido (FDA), lignina e digestibilidade in vitro da matéria seca (DIVMS). As silagens de Rumbosol 91
View details →DOI: 10.1590/s0102-09352006000100015 Negative / Null Result ReportOpen accessPublic aspects of medicine
E. Lubinga, A.A. Maes, C.J.M. Jansen · 2016 · SAHARA-J
Most existent research on the effects of interpersonal discussions about health campaign messages is based on surveys. In this study, we analysed actual conversations about an HIV/AIDS poster to find out possible effects. Young South African women in 59 dyads (n = 118) participated in conversations about a deliberately puzzling HIV and AIDS poster that cautioned the target group to be faithful to one sexual partner. We measured their comprehension of the poster and beliefs about the message, before and after the conversations. Overall, actual comprehension (AC) was low, and we observed a large
View details →DOI: 10.1080/17290376.2016.1197146 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Maja Ivanovski, Miha Mrak, Anja Zupan Mežnar et al. · 2022 · Journal of Cardiovascular Development and Disease
Conduction system pacing (CSP) modalities, including His-bundle pacing (HBP) and left bundle branch pacing (LBBP), are increasingly used as alternatives to biventricular (BiV) pacing in heart failure (HF) patients scheduled for pace and ablate strategy. The aim of the study was to compare clinical outcomes of HF patients with refractory AF who received either BiV pacing or CSP in conjunction with atrio-ventricular node ablation (AVNA). Fifty consecutive patients (male 48%, age 70 years (IQR 9), left ventricular ejection fraction (LVEF) 39% (IQR 12)) were retrospectively analysed. Thirteen pati
View details →DOI: 10.3390/jcdd9070209 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Shyamal Patel, Lucy Rose Howroyd, Helen Bucknall et al. · 2025 · CVIR Endovascular
Abstract Background Bronchial artery embolisation (BAE) is considered the most effective non-surgical technique for management of moderate-massive haemoptysis. Associated risks include neurological compromise such as stroke and spinal cord ischaemia. We aim to evaluate post-procedural outcomes and complication rates. Materials and methods A single-centre retrospective observational study was conducted for BAE cases performed between January 2002-June 2022 in a London teaching hospital. Data was collected from electronic medical records and Picture Archiving Communications System (PACS). Primar
View details →DOI: 10.1186/s42155-025-00551-0 Negative / Null Result ReportOpen accessEnvironmental technology. Sanitary engineering
Igor Esau, Mikhail Tolstykh, Rostislav Fadeev et al. · 2018 · Environmental Research Letters
Systematic errors in forecast near-surface air temperature (SAT) still constitute a considerable problem for numerical weather prediction (NWP) at high latitudes. Numerous studies in the past have attempted to reduce this problem through recalibration of physical parameterization schemes and better approximation of the surface energy budget. The errors, however, remain despite notable improvements in the overall weather forecast performance. This study looks at the problem from a different perspective. It analyzes asymmetries in the SAT forecast errors. The study reveals a statistical pattern
View details →DOI: 10.1088/1748-9326/aaecfb Negative / Null Result ReportMedicine
Anusuya, Balaji, Manikandan · 2026 · Journal of Indian Society of Periodontology
Periodontal regeneration aims to restore the natural structure of the periodontium, therefore improving the long-term stability and function of the affected teeth. Traditional bone graft materials such as allografts, autografts,…
View details →DOI: 10.4103/jisp.jisp_210_24 Negative / Null Result ReportMedicine
Ng, Chu, Chan et al. · 2026 · Journal of gastroenterology and hepatology
Management of malignant colorectal polyp has been a treatment dilemma for clinicians. This study aims to evaluate the long-term survival outcome of patients with and without salvage surgery after local excision. From January 2000 to…
View details →DOI: 10.1111/jgh.70506 Negative / Null Result ReportOpen accessMicrobiology
Zhuo Li, Yuan Zong, Dayu Chen et al. · 2025 · Frontiers in Cellular and Infection Microbiology
ObjectiveTo compare and analyze the efficacy and safety of different antifungal drug treatment regimens for patients with invasive pulmonary aspergillosis (IPA) in the intensive care unit (ICU).MethodsWe retrospectively collected the clinical data of patients with IPA in the ICU in two grade-A tertiary hospitals from January 2019 to January 2024 using the HIS system and compared the clinical efficacy, incidence of adverse drug reactions (ADRs), and all-cause mortality at discharge among different antifungal treatments, such as voriconazole alone, caspofungin alone, and a combination of voricon
View details →DOI: 10.3389/fcimb.2025.1584950 