Negative / Null Result Report
Ibrahim EA, Alper E · 2026 · Preprint
Abstract Purpose: PSMA PET/CT has transformed prostate cancer management, yet its diagnostic utility is not absolute. It fails to detect PSMA-suppressed disease variants, including treatment-induced neuroendocrine prostate cancer (t-NEPC)…
View details →DOI: 10.21203/rs.3.rs-9598282/v1 Negative / Null Result ReportMedicine
Yokoyama S, Shimada M, Nakagawa J et al. · 2026 · European journal of drug metabolism and pharmacokinetics
Background and objective Vadadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, is transported into hepatocytes via OATP1B1, which is encoded by the SLCO1B1 gene. Although interindividual variability in vadadustat…
View details →DOI: 10.1007/s13318-026-01005-1 Negative / Null Result ReportMedicine
Chen Y, Ren Z, Yan J et al. · 2026 · Urology
Objective To elucidate the association of endogenous circulating testosterone and its related substances with the onset and severity of stress urinary incontinence (SUI) in postmenopausal women. Patients and methods A comparative analysis…
View details →DOI: 10.1016/j.urology.2026.04.047 Negative / Null Result ReportMedicine
Sayur V, Uc C, Baki B et al. · 2026 · Hernia : the journal of hernias and abdominal wall surgery
Background and aim With the increasing use of digital platforms in surgical education, YouTube has become a widely accessible resource for trainees. However, the absence of peer review raises concerns regarding the reliability and…
View details →DOI: 10.1007/s10029-026-03721-8 Negative / Null Result ReportOpen accessMedicine
Koca SB, Kırkgöz T, Kara L et al. · 2026 · BMC endocrine disorders
BACKGROUND: Spexin has an inhibitory effect on the hypothalamus (GnRH expression), pituitary (LH and FSH expression) and ovary (estradiol expression). However, Phoenixin potentiate GnRH-stimulated GnRH receptor expression. Our aim is to…
View details →DOI: 10.1186/s12902-026-02268-0 Negative / Null Result Report
Çiğri E, Çatan İnan F, Gülten S et al. · 2026 · Preprint
Objective: In the present study, cardiovascular risk indices (Atherogenic Index of Plasma [AIP], Atherogenic Coefficient [AC], Castelli Risk Index-1 [CRI-1], and Castelli Risk Index-2 [CRI-2]) and bone mineral density (BMD SDS) were…
View details →DOI: 10.20944/preprints202605.2036.v1 Negative / Null Result ReportMedicine
Altun MNŞ, Yıldız İ · 2026 · Journal of pediatric nursing
Purpose This study aimed to determine the levels of e-health literacy and quality of life in adolescents with Congenital Heart Disease (CHD), to examine associated factors, and to explore the relationship between e-health literacy and…
View details →DOI: 10.1016/j.pedn.2026.04.024 Negative / Null Result ReportMedicine
Sun X, Zhou Q, Qian W et al. · 2026 · BMC medical education
Background Teaching postoperative follow-up for renal cell carcinoma (RCC) is challenging during brief urology rotations. We evaluated a structured module based on a simplified risk model (IMDB: venous invasion, tumor size ≥ 7 cm, systemic…
View details →DOI: 10.1186/s12909-026-09711-9 Negative / Null Result ReportOpen accessMedicine
Mitsea A, Christoloukas N, Rontogianni A et al. · 2026 · Journal of imaging
AI methods (machine learning and deep learning methods) presented promising results concerning the accuracy of dental age estimation and sex determination. Therefore, this pilot study aims to evaluate the efficacy of an artificial…
View details →DOI: 10.3390/jimaging12060239 Negative / Null Result Report
Ye Z, Men R, Shen Y et al. · 2026 · Preprint
Abstract Purpose: The VIATORR Controlled Expansion (VCX) stent-graft was developed to allow more precise control of shunt diameter during transjugular intrahepatic portosystemic shunt (TIPS) creation. However, real-world data on its actual…
View details →DOI: 10.21203/rs.3.rs-9743027/v1 Negative / Null Result ReportOpen accessMedicine
Ulas O, Yuceer RO, Hasbek Z et al. · 2025 · Medicina (Kaunas, Lithuania)
Background and Objectives : Neuroendocrine neoplasms are heterogeneous tumours arising from endocrine gland cells and the neuroendocrine system. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) constitute two-thirds of this tumour…
View details →DOI: 10.3390/medicina61111952 Negative / Null Result ReportMedicine
Silva VBC, Lucina SB, Wolf M et al. · 2026 · American journal of veterinary research
Objective To assess right ventricular (RV) systolic function using conventional echocardiography and advanced techniques, including strain and tissue motion annular displacement (TMAD), in dogs with and without pulmonary hypertension (PH).…
View details →DOI: 10.2460/ajvr.26.03.0107 Negative / Null Result ReportMedicine
Çerçer Z, Biçer Şahin F, Kanarya T · 2026 · Journal of human lactation : official journal of International Lactation Consultant Association
Background and aim It is important to include fathers in the evaluation of the breastfeeding process. This study aimed to assess fathers' breastfeeding attitudes and participation. Methods The cross-sectional study data were collected…
View details →DOI: 10.1177/08903344261434532 Negative / Null Result ReportMedicine
Igarashi A, Rekate A, Fujiwara K et al. · 2026 · Acta ophthalmologica
Purpose To evaluate whether early postoperative corneal thickness is associated with 12-month endothelial cell and visual outcomes after Descemet membrane endothelial keratoplasty (DMEK). Methods This retrospective multicentre study…
View details →DOI: 10.1111/aos.70166 Negative / Null Result ReportMedicine
Pillet P, Tremblay-Mercier J, Picard C et al. · 2026 · Neurobiology of aging
Preclinical studies consistently associate body temperature with tau phosphorylation in the brain. This study examined the relationship between body temperature taken at lumbar puncture (LP) and CSF pTau181 levels in 142 cognitively…
View details →DOI: 10.1016/j.neurobiolaging.2026.06.003 Negative / Null Result Report
CAI J, ZHAO P, LIN R et al. · 2025 · Preprint
Abstract The purpose of this study is to analyze the relationship between RPE-based method and internal training load (%HRavg, Banister's TRIMP, and Edward's TL) among high-level female volleyball players. 31 Chinese youth high-level…
View details →DOI: 10.21203/rs.3.rs-7342917/v1 Negative / Null Result ReportMedicine
Hamama I, Katodia V, Landry NM et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM
Objectives Hypoglycemia is a common metabolic problem in newborns, often asymptomatic but can lead to cognitive impairment and neuromotor delays. This study assesses the practicality and accuracy of whole blood capillary bedside glucose…
View details →DOI: 10.1515/jpem-2025-0736 Negative / Null Result ReportMedicine
Bakaç E, Bayburt KA, Diker N et al. · 2026 · Cranio : the journal of craniomandibular practice
Objective To assess early temporomandibular joint (TMJ) adaptation by evaluating angular and volumetric changes of the mandibular condyle relative to the cranial base in skeletal Class III patients following orthognathic surgery using…
View details →DOI: 10.1080/08869634.2026.2656900 Negative / Null Result Report
Han H, Huh Y, Lee SW et al. · 2026 · Preprint
Abstract Background: Electroencephalography (EEG) has emerged as a promising biomarker for predicting motor recovery in stroke patients undergoing non-invasive brain stimulation (NIBS), including repetitive transcranial magnetic…
View details →DOI: 10.21203/rs.3.rs-9648366/v1 Negative / Null Result ReportOpen accessMedicine
Elyasi B · 2026 · Veterinary medicine and science
Background The main goal of this study was to identify various brightness, motion and Doppler echocardiographic variables in small-breed dogs with myxomatous mitral valve disease. Animals Sixty client-owned small-breed dogs with mitral…
View details →DOI: 10.1002/vms3.70922 Negative / Null Result ReportOpen accessMedicine
Aydemir M, Sarkılar G, Atay T et al. · 2026 · Turk gogus kalp damar cerrahisi dergisi
Background Hypotension during anesthesia induction is a clinically significant event linked to perioperative complications. This study aimed to assess if arterial stiffness and stiffness index, measured by Doppler ultrasonography (USG),…
View details →DOI: 10.4274/tjtcs.2025.28548 Negative / Null Result ReportMedicine
Kook PH · 2026 · Journal of feline medicine and surgery
ObjectivesIt remains unclear whether pancreatic lipase immunoreactivity (PLI) and lipase activity similarly reflect clinical status and disease severity in cats with suspected pancreatitis. This retrospective cohort study aimed to directly…
View details →DOI: 10.1177/1098612x261451449 Negative / Null Result ReportMedicine
Sakai M, Miyati T, Ohno N et al. · 2026 · Magnetic resonance imaging
Purpose To apply dynamical network biomarker (DNB) theory to diffusion MRI and develop the diffusion MRI-derived DNB (dMRI-DNB) index for evaluating neurofluid fluctuation in idiopathic normal pressure hydrocephalus (iNPH). Methods…
View details →DOI: 10.1016/j.mri.2026.110728 Negative / Null Result Report
SHEN Z, LIU Y, LIU Y et al. · 2025 · Preprint
Abstract Purpose To analyze the clinical features of ocular surface diseases caused by Epstein-Barr virus (EBV) infection. Methods A retrospective case series study was conducted. Data from 48 patients (54 eyes) with EBV infection who…
View details →DOI: 10.21203/rs.3.rs-8349333/v1 Negative / Null Result ReportMedicine
Zhang C, Xie C, Zhang Z et al. · 2026 · Pathogens (Basel, Switzerland)
Background Sepsis, a life-threatening organ dysfunction caused by dysregulated host responses to infection, frequently involves impaired macrophage efferocytosis that leads to apoptotic cell accumulation, secondary necrosis, and persistent…
View details →DOI: 10.3390/pathogens15060596 Negative / Null Result ReportMedicine
Ito K, Hiranaka T, Basaqr AA et al. · 2026 · Orthopaedics & traumatology, surgery & research : OTSR
Background Kinematic alignment (KA) aims to restore the distal and posterior joint surfaces by matching the resected bone to the implant thickness. However, whether KA also accurately reproduces the anterior femoral anatomy, including the…
View details →DOI: 10.1016/j.otsr.2026.104767 Negative / Null Result ReportMedicine
Barman Kakil Ş, Sarı SA, Hazar L · 2026 · Current eye research
Purpose To evaluate retinal and optic nerve head microcirculation in children with dyslexia using optical coherence tomography angiography (OCTA) and to explore whether retinal microvascular parameters differ between dyslexic and typically…
View details →DOI: 10.1080/02713683.2026.2667330 Negative / Null Result ReportMedicine
Jiang C, Cheng P, Liu Y et al. · 2025 · Journal of pediatric orthopedics
Introduction Imaging-based measurement indices of patellar height are essential for diagnosing patella alta in children and adolescents. The Patellotrochlear Index (PTI) measures the cartilaginous anatomy which is crucial for identifying…
View details →DOI: 10.1097/bpo.0000000000003057 Negative / Null Result ReportMedicine
Gül O, Ayazoglu MA, Yazıcı A et al. · 2026 · Journal of shoulder and elbow surgery
Background Perianchor fluid collection may differ according to anchor material following arthroscopic rotator cuff repair (ARCR), but its relationship with tendon healing remains unclear. This study aimed to compare perianchor fluid…
View details →DOI: 10.1016/j.jse.2026.05.033 Negative / Null Result ReportMedicine
Kocak OF, Alpayci M, Demir CY et al. · 2025 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Objective To determine the frequency and severity of joint hypermobility (JH) in rhinoplasty patients and to assess rhinoplasty satisfaction in rhinoplasty cases with JH. Study design Comparative cross-sectional study. Place and Duration…
View details →DOI: 10.29271/jcpsp.2025.12.1603 