A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19875 results in Negative / Null Result Report · page 449 of 663
Ahmed A, Ahmed A, Zahra Z et al. · 2025 · Physiology & behavior
Introduction Despite emerging evidence on oxytocin's role in eating disorders,there is a need for a comprehensive review to integrate findings across neurobiological, genetic, hormonal, and therapeutic dimensions. This scoping review…
Ingram I, Hughes MA · 2024 · Journal of laparoendoscopic & advanced surgical techniques. Part A
Background: Surgeons are exposed to unavoidable distractions while operating. Distractions can cause stress, and stress can impair cognition and motor skills to the detriment of surgeon performance. This study assessed the impact of…
Zhang Y, Wen Z, Xia C et al. · 2024 · Heliyon
Dyslipidemia has been implicated in autoimmunity; however, its association with myasthenia gravis (MG) prognosis is unclear. We aimed to investigate the correlation between baseline lipid profiles and risk of MG worsening. This 7-year…
Williams KJ · 2025 · Current opinion in lipidology
Purpose of review For many years, inflammation has been a major concept in basic research on atherosclerosis and in the development of potential diagnostic tools and treatments. The purpose of this review is to assess the performance of…
Demir S, KÖYLÜ MT · 2023 · Preprint
INTRODUCTION To examine the ability of changes in optical coherence tomography angiography (OCTA) values to predict progression in the visual field (GA) and retinal nerve fiber layer (RNFL) in patients with glaucoma progression. METHODS…
Basu S, Gupta S, De R et al. · 2024 · Preprint
ABSTRACT Background and Objectives Microcytic hypochromic anemia is the most common feature of alpha-thalassemia and depends on the number of alpha genes deleted. Therefore, in this study, we aim to determine the most common deletion…
Kaşkal M, Bucci T, Alobaida M et al. · 2025 · European journal of clinical pharmacology
BACKGROUND: Chronic pericarditis is associated with significant cardiovascular morbidity, including atrial fibrillation (AF), heart failure (HF), and stroke. Colchicine is widely used in pericarditis management for its anti-inflammatory…
Koivunen P · 2026 · Current opinion in otolaryngology & head and neck surgery
Purpose of review Systematic follow-up protocols, often including regular imaging, are an essential component of posttreatment care for head and neck cancer, aimed at the early detection of disease relapse and mitigating treatment-related…
Luo L, Zhang Z, Zeng H et al. · 2025 · Journal of gastrointestinal oncology
Background The prognosis of patients with gastric cancer with peritoneal metastasis (GCPM) is exceedingly poor. This study evaluated the efficacy and safety of hyperthermic intraperitoneal chemotherapy (HIPEC) with paclitaxel combined with…
de Miranda NFCC, Smit VTHBM, van der Ploeg M et al. · 2025 · Cellular oncology (Dordrecht, Netherlands)
The relationship between bacterial activity and tumorigenesis has gained attention in recent years, complementing the well-established association between viruses and cancer. A recent study employed immunodetection of lipopolysaccharide…
Li X, Ji X, Shan J et al. · 2026 · Annals of medicine
Background and objectives Aquaporin-1 (AQP1) is a well-characterized transmembrane water channel widely expressed in the peripheral nervous system (PNS), where it contributes to water balance and regulation of the local neural…
Vetter P, Cabecinhas ARG, Schibler M et al. · 2026 · Antimicrobial agents and chemotherapy
Immunocompromised patients are at risk of developing severe influenza, with protracted viral shedding and development of resistance-associated mutations under antiviral treatment. We report a case series of severely immunocompromised…
Herrero C, Wasterlain A, Bloom DA et al. · 2024 · Bulletin of the Hospital for Joint Disease (2013)
Purpose The purpose of this study was to compare regimens of eccentric exercise and dry-needling, with and without an ultrasound-guided leukocyte-poor platelet-rich plasma (LP-PRP) injection, in patients with patellar tendinopathy. Methods…
Yu D, Song Z, Liu Y et al. · 2024 · Preprint
Abstract Background Ursodeoxycholic acid (UDCA) was reported to reduce susceptibility to SARS-CoV-2 infection by downregulating farnesoid X receptor (FXR) -ACE2 signaling. However, we found a different story in real-world clinical studies.…
Bharti A, Palta A, Bedi RK et al. · 2024 · The Indian journal of medical research
Background & objectives The newer technique using an innovative volume conductivity scatter (VCS) technology is emerging as a surrogate for sepsis diagnosis. The VCS technology offers a more objective method to measure cell volume (V),…
Sust L, Schoedel R · 2024 · Preprint
Digitalization has created an unparalleled freedom of choice in music consumption, pronouncing inter- and intraindividual differences in everyday listening behavior. To shed light on the factors involved in natural music choices, the…
Rahner A, Eickholz P, Gueth JF et al. · 2025 · Clinical oral implants research
Objectives In vitro analysis of the influence of vertical peri-implant soft tissue thickness (STT) on nonsurgical and surgical implant surface decontamination efficacy. Material and methods A total of 360 implants were dipped in indelible…
Jeong J, Goh J, Nam C et al. · 2025 · Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Tumors originating from the anal sacs and perianal glands are common tumors of the perianal region. However, differentiation of perianal tumors based on CT findings remains challenging because perianal tumors can show overlapping CT…
Komarova NL, Pritchard J, Wodarz D · 2024 · Preprint
Principles of evolution in spatially structured expanding populations have recently received much attention, but more work remains to be performed, especially for complex, multi-step evolutionary processes, where mutations are accumulated…
Sewell KM, Oriakhi K, Ngo Tenlep SY et al. · 2026 · Ecotoxicology and environmental safety
Organophosphate flame retardants (OPFRs) are used in many consumer products, and their presence in our environment raises concerns about potential health dangers. In humans, exposure to OPFRs, such as tris(1,3-dichloro-2-propyl) phosphate…
Kotha S, Baisya R, Yerram KV et al. · 2025 · Mediterranean journal of rheumatology
Background Lupus enteritis (LE) is the most common serious gastrointestinal manifestation of SLE. Indian literature on LE is limited, while most of the data comes from China and Western series with recent efforts on developing prediction…
Gow J, Roofeh D · 2025 · BMC rheumatology
Background Giant cell arteritis (GCA) is a large vessel vasculitis characterized by granulomatous inflammation classically affecting the carotid artery branches. GCA most often presents with one or more classic clinical features which…
Patel SA, Roy JM, Musmar B et al. · 2024 · Neurosurgical focus
Objective Preclinical studies suggest that robotic carotid artery stenting (CAS) could be superior to manual CAS. However, very limited comparative data exist for patients who have undergone robotic versus manual CAS. In addition, no data…
Goudman L, Pilitsis JG, Billet B et al. · 2024 · Anaesthesia
The numerical rating scale and visual analogue scale are used to quantify pain intensity. However, it has not yet been explored whether these scores are interchangeable in adults with chronic pain. Data from the prospective multicentre…
Croes M, Kreuwels B, Verheyen S · 2024 · Preprint
Research shows that when people take pictures of items around them, they have impaired memory for these items. Two theoretical accounts have emerged for this so-called photo-taking impairment effect: the offloading hypothesis and the…
Millan B, Hoogenes J, Uy M et al. · 2025 · Canadian Urological Association journal = Journal de l'Association des urologues du Canada
Introduction We aimed to assess early and late continence rates post-robot-assisted radical prostatectomy (RARP), comparing posterior reconstruction (PR) urethrovesical anastomosis (UVA) to conventional urethrovesical anastomosis (C-UVA).…
Caldani S, Khoury E, Delorme R et al. · 2025 · Brain sciences
Background/Objectives: Children with dyslexia report poor motor control; several studies have shown poor eye movements control during reading and important body instability in these children. The present study aimed to test in children…
Egger M, Bergmann J, Krewer C et al. · 2024 · Journal of neurologic physical therapy : JNPT
Background and purpose Functional recovery after stroke is often limited, despite various treatment methods such as robot-assisted therapy. Repetitive sensory stimulation (RSS) might be a promising add-on therapy that is thought to…
Vuppu DP, Rajanbabu A, Nair IR et al. · 2025 · Ecancermedicalscience
The latest International Federation of Gynaecology and Obstetrics (FIGO) staging for endometrial cancer incorporated molecular profiles and histopathological factors into the basic staging framework. This study was done to determine its…
Marouf SP, Meskar Z, Rezaei N · 2026 · Discover oncology
Insulin resistance (IR) has emerged as a metabolically relevant contributor to the development and progression of breast cancer (BC), with a case fatality of nearly 15%. IR mainly shows a relationship with obesity, type 2 diabetes mellitus…