Negative / Null Result ReportOpen accessMedicine
Kądziela M, Migdalska-Sęk M, Domańska-Senderowska D et al. · 2026 · International journal of molecular sciences
Vitiligo is a chronic autoimmune skin disorder characterized by progressive melanocyte loss and depigmented skin lesions, whose pathogenesis has been attributed to genetic and immunological factors. The aim of this exploratory study was to…
View details →DOI: 10.3390/ijms27115084 Negative / Null Result ReportMedicine
Anderson N, Kimlin K, O'Rourke JL et al. · 2026 · Pediatric research
Background Congenital hearing loss can significantly affect childhood development, yet more than half of affected infants present without identifiable risk factors. A possible association between maternal diabetes and congenital hearing…
View details →DOI: 10.1038/s41390-026-04846-3 Negative / Null Result ReportMedicine
Li Y, Zhu YX, Qiu Y et al. · 2026 · Clinical nephrology
Objective The association between the atherogenic index of plasma (AIP) and chronic kidney disease (CKD) among individuals with different metabolic syndromes remains inadequately characterized. The aim of this study is to assess the…
View details →DOI: 10.5414/cn111841 Negative / Null Result ReportMedicine
Mostofi K, Caragliano G · 2026 · The Journal of hospital infection
Background Surgical site infections (SSIs) are a major complication of spinal surgery. The influence of tattoos overlying the operative incision has not been previously evaluated as a risk factor in this context. Methods Retrospective…
View details →DOI: 10.1016/j.jhin.2026.06.006 Negative / Null Result Report
Chen F, You R, Liu Y et al. · 2026 · Preprint
Background and Aims MASLD has become the most prevalent chronic liver disease globally. Although MVPA and plasma fatty acids have been individually studied in relation to metabolic health, their independent and combined associations with…
View details →DOI: 10.64898/2026.06.05.26354982 Negative / Null Result ReportMedicine
Karabulut Ü, Yolaçan R, Ebik B et al. · 2026 · BMC gastroenterology
Background Duodenogastric reflux (DGR), defined as the retrograde flow of duodenal contents into the stomach, has an incompletely understood pathophysiology. This study aimed to evaluate the relationship between DGR and clinical,…
View details →DOI: 10.1186/s12876-026-05066-z Negative / Null Result ReportOpen accessMedicine
Maher AA, Maad AH, Al-Jaufy AY et al. · 2026 · Frontiers in medicine
Background Burn wound infections (BWIs) represent a major cause of morbidity and mortality among hospitalized burn patients. Pseudomonas aeruginosa is recognized for its ability to acquire multidrug resistance (MDR) and form biofilms that…
View details →DOI: 10.3389/fmed.2026.1762684 Negative / Null Result Report
Alayande AA, Williams JE, Olawuni DA et al. · 2026 · Preprint
Abstract Introduction: Abnormal anthropometric indices in children and adolescents, can potentially increase the risk of developing elevated blood pressure at a younger age. Children and adolescents with abnormal blood pressure at an early…
View details →DOI: 10.21203/rs.3.rs-8625118/v1 Negative / Null Result ReportOpen accessMedicine
Böckels L, Lisnic V, Alexa D et al. · 2026 · Journal of clinical medicine
Background/Objectives: Relapsing-remitting multiple sclerosis (RRMS) is frequently associated with anxiety and depressive symptoms, which significantly impact quality of life and clinical outcomes. The Hospital Anxiety and Depression Scale…
View details →DOI: 10.3390/jcm15114165 Negative / Null Result ReportMedicine
Shimada H, Lee S, Doi T et al. · 2026 · Gerontology
Introduction Walking speed is widely recognized as an informative indicator of physical capability in later life and is frequently used to evaluate mobility and functional health in older adults. Although the measurement of community…
View details →DOI: 10.1159/000550778 Negative / Null Result Report
Demirbaş SC, Kaba İ, Yilmaz M et al. · 2026 · Preprint
Abstract Objective Childhood obesity is a significant public health issue. Meteorin-like protein (Metrnl) is a newly identified adipomyokine that plays a role in energy metabolism and inflammatory processes. The aim of this study was to…
View details →DOI: 10.21203/rs.3.rs-9763274/v1 Negative / Null Result ReportOpen accessMedicine
Rosi Júnior J, Telles JPM, Santana LS et al. · 2026 · Arquivos de neuro-psiquiatria
Background Alpha 1-antitrypsin (A1AT) helps maintain vascular-wall integrity, but its role in the formation and rupture of intracranial aneurysms is unclear. Objective To compare A1AT levels between patients with ruptured and unruptured…
View details →DOI: 10.1055/s-0046-1820525 Negative / Null Result ReportMedicine
Kavrul Kayaalp G, Balcı MC, Kürkçü Güneş D et al. · 2026 · Cardiology in the young
Background Early identification of familial hypercholesterolaemia is critical to prevent long-term cardiovascular complications. This study assessed diagnostic features and age at diagnosis in children with familial hypercholesterolaemia…
View details →DOI: 10.1017/s104795112611302x Negative / Null Result ReportMedicine
Shinkawa K, Yoshida S, Nakao YM et al. · 2026 · Clinical and experimental nephrology
Introduction The clinical characteristics of patients with nephrotic syndrome undergoing in-hospital rehabilitation are not well-understood, and the effects of exercise on acute kidney injury (AKI) or venous thromboembolism (VTE) in this…
View details →DOI: 10.1007/s10157-026-02832-x Negative / Null Result Report
Conteville LV, Fernandes JPA, Frajacomo FT et al. · 2026 · Preprint
Abstract OBJECTIVES To examine the association between longitudinal trajectories of anthropometric nutritional status, physical activity, and overall survival among women with endometrial cancer. METHODS In a prospective cohort study, we…
View details →DOI: 10.21203/rs.3.rs-9438420/v1 Negative / Null Result ReportOpen accessMedicine
Kim T, Oh SB, Choi HJ et al. · 2025 · Genes
Objective Suicide attempts have become one of the most serious problems worldwide in recent years. Suicide attempts are known to be genetically highly associated with serotonin and BDNF in international studies. Methods In this study, we…
View details →DOI: 10.3390/genes16111304 Negative / Null Result ReportMedicine
Devi Krishna RB, Mathews SG, Agarwal P et al. · 2026 · Biochemical genetics
To assess the potential association between LRP1 (rs715948) and PAI1 (rs2227631, rs1799889) gene variation and ovarian cancer (OC) susceptibility. This study evaluated the genotypic and allelic distributions of LRP1 gene and PAI1 gene…
View details →DOI: 10.1007/s10528-026-11331-3 Negative / Null Result Report
Ma L, Ma Y, Huang Z et al. · 2026 · Preprint
Abstract Background: Stroke remains a leading cause of death and disability among older adults. Depressive symptoms and low social participation may increase stroke risk via behavioural and biological pathways. This study examined the…
View details →DOI: 10.21203/rs.3.rs-8765182/v1 Negative / Null Result ReportOpen accessMedicine
Majmudar IP, Aggarwal S, Hamzeh N et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To determine if there is an association between surgeon-patient sex concordance and post-surgical complications for cataract surgeries. Patients and methods In this 16-year retrospective cohort study, data was collected from the…
View details →DOI: 10.2147/opth.s612384 Negative / Null Result ReportMedicine
Foo JF, Haddow K, Jones S et al. · 2026 · The Journal of laryngology and otology
Objectives To investigate whether socioeconomic deprivation is associated with residual or recurrent cholesteatoma following primary mastoidectomy. Methods A retrospective cohort study included all patients undergoing primary mastoidectomy…
View details →DOI: 10.1017/s002221512610499x Negative / Null Result ReportMedicine
Peng P, Guo Y, Zhu Y · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Given that long-term anticoagulant therapy is required in many clinical scenarios, continuous safety monitoring of direct factor Xa inhibitors is of great importance. To date, the renal safety of these agents remains a subject…
View details →DOI: 10.17219/acem/210295 Negative / Null Result ReportMedicine
Zhai L, Fang C, Wang L et al. · 2026 · Scientific reports
There is little evidence about the susceptible exposure window of maternal depression during pregnancy and preterm birth in China. We aimed to assess the trimester-specific association of depression during pregnancy with preterm birth, and…
View details →DOI: 10.1038/s41598-026-56342-7 Negative / Null Result ReportOpen accessMedicine
Metwally YF, Zahran RF, El Sadda RR et al. · 2026 · Discover oncology
Background Lung cancer remains the leading cause of cancer-related deaths worldwide. Despite advances in diagnostics and treatment, most patients are diagnosed at advanced stages. Genetic variants such as single nucleotide polymorphisms…
View details →DOI: 10.1007/s12672-026-04972-8 Negative / Null Result ReportMedicine
Aryal SB, Raj Joshi D · 2026 · Journal of Nepal Health Research Council
Background Homocysteine (Hcy) contributes to oxidative stress and renal injury by generating reactive oxygen species and reducing heme oxygenase-1 levels. Elevated Hcy (Hhcy) may worsen outcomes after acute renal failure(ARF), promoting…
View details →DOI: 10.33314/jnhrc.v23i03.4635 Negative / Null Result ReportMedicine
Bellos I, Marinaki S, Benetou V · 2026 · Journal of clinical medicine
Background/Objectives : Composite endpoints are commonly used in chronic kidney disease (CKD) trials to enhance statistical efficiency but may not reflect clinically meaningful outcomes. We assessed agreement between composite endpoints…
View details →DOI: 10.3390/jcm15124840 Negative / Null Result ReportMedicine
Pires E Silva C, Malaspina OA, Basting RT · 2026 · General dentistry
Light transmission during photopolymerization is reduced by the intrinsic optical properties of ceramics, which vary with material and thickness. The higher translucency of lithium disilicate contrasts with the chemical inertness and…
Negative / Null Result ReportMedicine
Hakim MS, Hashimi MH, Saeed KM et al. · 2026 · Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit
Background Viral hepatitis and HIV infections are common public health concerns among injecting drug users, however, there is limited evidence on their seroprevalence in Afghanistan. Aim To determine the seroprevalence of hepatitis B,…
View details →DOI: 10.26719/2026.32.2.61 Negative / Null Result ReportOpen accessMedicine
Popovic R, Cvitanovic S, Sarac I et al. · 2026 · Cureus
Objective To assess parents' knowledge of recommended oral-hygiene practices for children and to describe oral-hygiene behaviors within families (parents and children), as well as factors associated with children's oral-hygiene outcomes.…
View details →DOI: 10.7759/cureus.100792 Negative / Null Result ReportMedicine
Famuyide L, Patel J, Nembhard WN · 2026 · Birth defects research
Background Hypospadias is one of the most common genital defects in boys, affecting about 1 in 125 live-born boys. Several studies have examined the association between a single environmental exposure and risk of hypospadias, but few have…
View details →DOI: 10.1002/bdr2.70022 Negative / Null Result ReportOpen accessMedicine
Ye B, Liu Y, Zhang J et al. · 2026 · Frontiers in nutrition
Background To investigate the associations between consumption of sugar-sweetened beverages (SSBs), artificially sweetened beverages (ASBs), and natural juices (NJs) and incident kidney stone disease (KSD), and to assess whether genetic…
View details →DOI: 10.3389/fnut.2026.1844118