A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19875 results in Negative / Null Result Report · page 438 of 663
Roganović, Zubović, Đorđević et al. · 2026 · Acta medica academica
To analyze the characteristics, etiology, diagnostic evaluation, management, follow-up, and outcomes of children with chronic neutropenia treated at a tertiary care pediatric hospital in Croatia. We retrospectively reviewed the…
Hardy, Hibbert, Tasker et al. · 2026 · Journal of feline medicine and surgery
To determine the frequency and clinical significance of discordant serum symmetric dimethylarginine (SDMA) and creatinine concentrations relative to glomerular filtration rate (GFR) in mature and senior hyperthyroid cats treated with…
Flavin, Vernon, Todd Cade et al. · 2026 · Journal of managed care & specialty pharmacy
Barth syndrome is an ultrarare, complex, multisystem, X-linked metabolic and neuromuscular disease, which poses significant and wide-ranging burden to patients and caregivers. Pharmacologic management focuses on treatment of disease…
Ani, Hameed · 2026 · Wiadomosci lekarskie (Warsaw, Poland : 1960)
Aim: This study aimed to evaluate the effectiveness of a structured intravenous infusion protocol in improving the quality of care and reducing IV-related complications among hospitalized patients. Materials and Methods: A purposive sample…
Wang, Leng · 2026 · The Journal of international medical research
ObjectiveAlthough renal failure is an important cause of death in the United States, recent mortality trends and subgroup differences remain insufficiently characterized. This nationwide ecological time-trend study examined renal failure…
Kim, Park, Park et al. · 2026 · American journal of physical medicine & rehabilitation
Lumbosacral radiculopathy often presents as back pain and lower limb weakness and is frequently encountered in rehabilitation medicine. Fibrocartilaginous embolism (FCE) is an uncommon but significant vascular cause of radiculopathy. It…
Peake, Swirbul, Rodio et al. · 2026 · Frontiers in digital health
Consistent client engagement with between-therapy session activities (i.e., homework) is a strong predictor of positive psychotherapy outcomes. Because traditional homework activities aren't always tailored to the individual, they can fail…
Jain, Kamboj, Sakale · 2026 · Journal of clinical orthopaedics and trauma
Hip preservation surgery (HPS) is increasingly performed in young and active patients with the aim of delaying or avoiding total hip arthroplasty (THA). Despite advances in preservation techniques, a proportion of patients eventually…
Elmansy, Elbqry, Qalawa et al. · 2026 · Frontiers in nutrition
Hemodialysis is a life-sustaining renal replacement therapy that removes metabolic waste products normally eliminated by the kidneys. Patients undergoing hemodialysis are required to adhere to strict fluid and dietary restrictions to…
Lin, Yu, Hu et al. · 2026 · Precision radiation oncology
The optimal management of locally advanced resectable esophageal squamous cell carcinoma (ESCC), particularly for cT3-4a disease, remains debated. This study aimed to compare the survival outcomes and toxicity profiles of neoadjuvant…
Kawakita, Hayasaka, Barake et al. · 2026 · Pregnancy (Hoboken, N.J.)
Prenatal phthalate exposure is linked to adverse reproductive and developmental outcomes and is consistently higher among non-Hispanic Black compared to non-Hispanic White pregnant individuals, yet the factors responsible for these…
Tilahun, Urge, Girma et al. · 2026 · Veterinary and animal science
The current study evaluated the effects of black cumin seed meal (BCSM) on growth performance, cecal microbiota, production efficiency, and cost efficiency in broiler chickens. A total of 144 one-day-old unsexed Cobb 500 broiler chicks…
Navidifar, Kaveh, Hosseini et al. · 2026 · Veterinary and animal science
Efficient estrus synchronization is important for improving reproductive performance in dairy herds; however, variations in ovarian activity among cows of different parities may influence responses to synchronization protocols. The present…
Naizabayev, Talgatov, Auyezkhanova et al. · 2026 · Molecules (Basel, Switzerland)
Palladium catalysts modified with chitosan (CS) and supported on MgO, SiO 2 , TiO 2 , and Al 2 O 3 were prepared by a precipitation method and evaluated in the low-temperature hydrogenation of 2-propen-1-ol. Chitosan was first deposited…
Zhou, Zhang, Wang et al. · 2026 · Molecules (Basel, Switzerland)
Recent studies indicate that ferroptosis shows unique advantages in oncotherapy, particularly in reversing multidrug resistance (MDR). Despite current therapeutic advancements, the treatment of high-incidence malignancies with dismal…
Baranowska, Kiss, Szeleszczuk · 2026 · Pharmaceutics
Dipeptidyl peptidase-4 (DPP-4) is an established therapeutic target in the treatment of type 2 diabetes mellitus (T2DM), primarily due to its role in regulating incretin activity and glucose homeostasis. Although clinically approved DPP-4…
Marín, Fuentes-Martín, Sánchez et al. · 2026 · Pharmaceutics
Background/Objectives: Microtubule-targeting agents represent a pillar of cancer chemotherapy; however, their clinical utility is constrained by significant toxicity, pharmacokinetic instability, and susceptibility to multidrug resistance…
Sevim M, Demir M, Eryılmaz R et al. · 2026 · Urology journal
Purpose To compare outcomes of super mini percutaneous nephrolithotomy (smPCNL) with extracorporeal shock wave lithotripsy (ESWL) for stones 1-2 cm. Materials and methods After receiving ethics committee approval for this study (Date:…
Kong Y, Fan J, Li Y et al. · 2026 · Aquaculture nutrition
Saline-alkali cultivation is a crucial approach to alleviate the fresh water crisis. However, prolonged saline-alkali stresses might bring adverse effects on fish growth, health, and even death. This study evaluated the effects of…
Li H, Li X, Gao W et al. · 2026 · Frontiers in sports and active living
Background Basketball requires players to perform complex technical actions under conditions of dynamic instability. Traditional stability and strength training mainly improves muscle strength; however, it is often insufficient for…
Lacayo M, Pless A, Wilde J et al. · 2026 · American journal of disaster medicine
Background Natural and man-made disasters displace millions of people each year. Children are disproportionately at risk due to their physiology and dependent living needs. Familial separation, resulting from displacement, causes physical,…
Yiğit E, Atsü S · 2026 · European journal of dental education : official journal of the Association for Dental Education in Europe
Objective This study examines differences in scores assigned to dental students' assignments when evaluated by two instructors and compares assessments conducted with a structured preclinical assessment form versus those without one.…
Sağlam H, Arslan H · 2026 · BMC oral health
Background The aim of this study is to investigate the association between preoperative anxiety and postoperative pain after endodontic treatment in vital symptomatic mandibular molar teeth. Methods 132 patients who came for endodontic…
Ogbe KU, Emmanuel VS, Somdare PO et al. · 2026 · Preprint
Abstract Background The aim of this study was to determine and compare the intestinal health status of Clarias gariepinus gotten from the wild and from the pond through histological, biochemical and parasitological studies. The intestine…
Lin J, Chen J, Wang D et al. · 2026 · Preprint
Abstract Objective : To investigate whether protrusive occlusal interference is related to anterior displacement of the temporomandibular joint disc based on clinical data, and to explore the relationship between the two and the superior…
Liu S, Li Z, Chen S et al. · 2026 · Frontiers in plant science
Introduction In recent years, the demand for high-nutrition fruits has increased. As a unique fruit tree in China, Cerasus humilis has both ecological and nutritional value. Water and fertilizer nutrition is closely related to plant growth…
van Mourik M, Spierings J, Koca P et al. · 2026 · Journal of tissue engineering and regenerative medicine
Providing a functional pericellular matrix (PCM) by fine-tuning the microenvironment of the articular chondrocytes (ACs) can greatly improve the outcomes of articular cartilage tissue engineering. While harvesting ACs with their PCM…
Yamazaki M, Ninomiya S, Hashizume A et al. · 2026 · Preprint
Abstract Background About half of both men and women have lower urinary tract symptoms, and aging is reported to have a significant impact on these symptoms. Lifestyle-related diseases such as diabetes, hypertension, and metabolic syndrome…
Akhras N, Antaki F, Mottet F et al. · 2026 · PLOS digital health
Bias and inequity in palliative care disproportionately affect marginalised groups. Large language models (LLMs), such as GPT-4o, hold potential to enhance care but risk perpetuating biases present in their training data. This study aimed…
Li J, Zhou X, Wang W et al. · 2026 · Frontiers in microbiology
Background Mycoplasma hyopneumoniae (Mhp), the etiological agent of enzootic pneumonia in pigs, poses significant challenges to swine production. This study evaluated the anti-Mhp efficacy of a novel enteric-coated granules of tylvalosin…