Negative / Null Result ReportMedicine
Gan, Abu Hassan, Tan et al. · 2026 · Therapeutic advances in neurological disorders
Acute attacks of aquaporin-4 antibody neuromyelitis optica spectrum disorder (AQP4-Ab NMOSD) are typically managed with intravenous methylprednisolone, with therapeutic plasma exchange (PLEX) reserved for severe episodes. Despite these…
View details →DOI: 10.1177/17562864261449515 Negative / Null Result ReportMedicine
Bedia Cadelo, García Feijoo, Zamorano-Fernandez et al. · 2026 · BMJ case reports
A boy in his early teens presented with transient visual disturbances and headache. Brain imaging revealed bilateral occipital infarctions, while vascular studies demonstrated bilateral V3 vertebral artery wall abnormalities with…
View details →DOI: 10.1136/bcr-2026-272989 Negative / Null Result ReportMedicine
Dong, Patel, Wang et al. · 2026 · Environment international
Phthalates are pervasive endocrine-disrupting chemicals widely used in consumer products. The wide use of many phthalates results in chronic human exposure to complex mixtures rather than single compounds. Despite extensive studies on…
View details →DOI: 10.1016/j.envint.2026.110332 Negative / Null Result ReportMedicine
Malzahn, Höft Budde, Kneißl et al. · 2026 · Innere Medizin (Heidelberg, Germany)
The German healthcare system, despite its high performance, fails to achieve the goal of needs-based service provision. Supply-induced demand, regional disparities and misaligned financial incentives lead to overuse, underuse and misuse of…
View details →DOI: 10.1007/s00108-026-02117-1 Negative / Null Result ReportMedicine
Faurholt-Jepsen, Hammershøi, Bruun et al. · 2026 · Journal of affective disorders
Distinguishing between bipolar disorder type I and II constitutes a significant clinical challenge that relies on retrospective patient recall. Misclassification carries risks of inappropriate pharmacological management. Digital…
View details →DOI: 10.1016/j.jad.2026.122027 Negative / Null Result ReportMedicine
He, Lin, Zhang et al. · 2026 · Diabetes research and clinical practice
Cardiovascular-kidney-metabolic (CKM) syndrome defines a pathophysiological continuum linking obesity, metabolic dysfunction, chronic kidney disease, and cardiovascular disease. Stages 0-3 represent a critical subclinical window for…
View details →DOI: 10.1016/j.diabres.2026.113336 Negative / Null Result ReportMedicine
Romero-Alfano, Prats, Raldúa et al. · 2026 · The Science of the total environment
Mixture toxicity studies on neuroactive chemicals remain scarce and often rely on simplified combinations of compounds with known modes of action (MoA), despite the frequent non-monotonicity of neuroactive responses. Furthermore, real…
View details →DOI: 10.1016/j.scitotenv.2026.181901 Negative / Null Result ReportMedicine
Lin, Li, Cheng et al. · 2026 · Briefings in bioinformatics
Current metabolomics approaches predominantly rely on group-level differential abundance screening. While effective for identifying biomarkers, this paradigm often overlooks upstream regulatory hubs and fails to resolve the…
View details →DOI: 10.1093/bib/bbag264 Negative / Null Result ReportMedicine
Oduncu, Zor, Çimen et al. · 2026 · Forensic science, medicine, and pathology
Gunshot wounds (GSW) pose serious risks to both mother and fetus. Determining the trajectory and cause of death in the fetus in GSW is of forensic importance. This study aims to contribute to the literature with two rare GSW cases leading…
View details →DOI: 10.1007/s12024-026-01271-0 Negative / Null Result ReportMedicine
Lu, Wang, Chen et al. · 2026 · Cell death discovery
Proper oocyte maturation is critical for female fertility, yet whether cuproptosis, a recently identified copper-dependent cell death pathway, affects meiotic maturation remains unknown. Here, we show that Cu(II)-elesclomol (ELC-Cu(II))…
View details →DOI: 10.1038/s41420-026-03168-x Negative / Null Result ReportMedicine
Walther, Hänel, Krohn et al. · 2026 · International journal of sports physiology and performance
To compare effects of block periodization against evenly distributed low-intensity training on endurance performance in well-trained junior cross-country (XC) skiers. Twenty junior cross-country skiers participated in a crossover design…
View details →DOI: 10.1123/ijspp.2025-0552 Negative / Null Result ReportMedicine
Gu, Wen, Liu et al. · 2026 · Circulation
Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion (ie, Na + /H + and Ca 2 + ) cycling underlies reduced cardiac contractility. The…
View details →DOI: 10.1161/circulationaha.126.079823 Negative / Null Result ReportMedicine
Srimanan, Sawangsribanterng, Poolsawat et al. · 2026 · Cureus
Internuclear ophthalmoplegia (INO) is a classic neuro-ophthalmologic syndrome caused by disruption of the medial longitudinal fasciculus (MLF), resulting in impaired adduction of the affected eye and abducting nystagmus of the…
View details →DOI: 10.7759/cureus.107359 Negative / Null Result ReportMedicine
Patel, Patel · 2026 · Cureus
Chronic pain is a complex phenomenon whose assessment involves not only physiological but also psychological and social components. Due to its subjective and variable nature, accurately measuring chronic pain remains challenging in both…
View details →DOI: 10.7759/cureus.109593 Negative / Null Result ReportMedicine
Ösken, Çetin · 2026 · Irish journal of medical science
Familial Mediterranean fever (FMF) is characterized by recurrent inflammatory attacks and marked clinical heterogeneity. Exertional leg pain (ELP) is a common but underrecognized manifestation. We aimed to evaluate the association of ELP…
View details →DOI: 10.1007/s11845-026-04511-y Negative / Null Result ReportMedicine
Friese, Wunderl, Jensch et al. · 2026 · American heart journal plus : cardiology research and practice
Arrhythmogenic cardiomyopathy (ACM) is a primary cardiomyopathy associated with mechanical and electrical dysfunction, making diagnosis a clinical challenge. This feasibility study investigates whether Optically Pumped Magnetometer…
View details →DOI: 10.1016/j.ahjo.2026.100813 Negative / Null Result ReportMedicine
Griffith, Zaidan, Gould et al. · 2026 · Cancers
Spinal ependymoma is the most common intramedullary spinal cord tumor in adults, and maximal safe resection is the cornerstone of treatment. Patients aged 75 years and older are underrepresented in surgical neuro-oncology cohorts. We…
View details →DOI: 10.3390/cancers18121927 Negative / Null Result ReportMedicine
Yerkezhan, Sagandykova, Baurzhan et al. · 2026 · Bioengineering (Basel, Switzerland)
Background . Recurrent respiratory papillomatosis (RRP) in children remains a pressing issue in pediatric otolaryngology, characterized by a chronic course, frequent relapses, and the need for repeat surgical interventions. The aim of this…
View details →DOI: 10.3390/bioengineering13060713 Negative / Null Result ReportMedicine
Tigli, Deniz, Taskin et al. · 2026 · Biomedicines
Background/Objectives : This study aimed to evaluate the association between the clinical parameters of vaginal infection-specifically the presence, type, number of concurrent symptoms, and recurrence frequency-and cervical cytology…
View details →DOI: 10.3390/biomedicines14061384 Negative / Null Result ReportMedicine
Yagdiran, Kirisci, Uslu et al. · 2026 · BMC nephrology
Pulmonary hypertension (PH) is a complex systemic disease. There are insufficient studies in the literature regarding its effect on renal hemodynamics following transplantation. This retrospective cohort study included 244 kidney…
View details →DOI: 10.1186/s12882-026-05156-w Negative / Null Result ReportMedicine
Boulmpou, Pagourelias, Zormpas et al. · 2026 · Journal of cardiovascular development and disease
Background : Predicting atrial fibrillation (AF) recurrence remains a major clinical challenge, as conventional echocardiographic parameters often fail to capture the complex electro-mechanical substrate of the arrhythmia. The prognostic…
View details →DOI: 10.3390/jcdd13060269 Negative / Null Result ReportMedicine
Wain, Steiner, Daddato et al. · 2026 · Journal of the American Geriatrics Society
More than one in four older adults experience a fall each year. While exercise programs are effective in reducing fall-related injuries (FRI), participation remains low due to access barriers. The primary aim of this study was to evaluate…
View details →DOI: 10.1111/jgs.70544 Negative / Null Result ReportMedicine
Zhang, Jia, Hou et al. · 2026 · Endocrine, metabolic & immune disorders drug targets
This study aimed to determine the relationship between Systemic Immune-Inflammation Index (SII) and muscle strength in patients with CKD. This cross-sectional study examined adults with CKD using data from the National Health and Nutrition…
View details →DOI: 10.2174/0118715303430103251204120642 Negative / Null Result ReportMedicine
Panwar, Amiri-Kazaz, Szczepaniec · 2026 · Environmental entomology
Amauromyza karli Hendel (Diptera: Agromyzidae) has recently emerged as a damaging stem-boring pest of quinoa in Colorado and other quinoa-producing regions of the United States. Severe infestations have been associated with substantial…
View details →DOI: 10.1093/ee/nvag069 Negative / Null Result ReportMedicine
Sia, Yew, Arumugam et al. · 2026 · Obstetrics and gynecology international
Estimated fetal weight (EFW) is a key determinant of obstetrical decision-making and an independent risk factor of high perinatal morbidity and mortality. However, routine ultrasound during pregnancy test is not universally available in…
View details →DOI: 10.1155/ogi/9992291 Negative / Null Result ReportMedicine
Snyder, Hillaker, Weppner · 2026 · Endocrinology, diabetes & metabolism
Growth hormone deficiency (GHD) is a common and clinically significant consequence of moderate-to-severe traumatic brain injury (msTBI). The glucagon stimulation test (GST) is widely used to assess growth hormone deficiency; however, the…
View details →DOI: 10.1002/edm2.70260 Negative / Null Result ReportMedicine
Chaudhary, Lammy, Grivas · 2026 · Neurosurgical review
Glioblastoma is an aggressive form of brain cancer and poses a challenge in treatment due to its profound heterogeneity and capacity for extensive infiltration into the brain parenchyma. Research has shown glioblastomas near the ependyma…
View details →DOI: 10.1007/s10143-026-04365-z Negative / Null Result ReportMedicine
Ciacciarelli, Nicolini, Saia et al. · 2026 · Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Infarct growth rate (IGR) is highly heterogeneous among ischemic stroke patients, reflecting a spectrum of progressor phenotypes with clinical implications. We aim to compare different imaging approaches to investigate stroke progressors…
View details →DOI: 10.1007/s10072-026-09148-4 Negative / Null Result ReportMedicine
Serttas, Uysal, Deği̇rmenci̇ et al. · 2026 · Injury
Urinary tract infection(UTI) is a common complication following hip fracture surgery in elderly patients. Urinary catheterization is frequently used to improve patient comfort during prolonged preoperative immobilization; however, its…
View details →DOI: 10.1016/j.injury.2026.113449 Negative / Null Result ReportMedicine
Aalibraheem, Lopez-Medina, Chahal et al. · 2026 · Pharmacogenetics and genomics
Drug-induced QT prolongation (diQTP) can lead to rare, but potentially fatal adverse effects of many medications, yet individual susceptibility varies due to both clinical and genetic factors. SDHAF3 p.F53L (rs62624461) is a genetic…
View details →DOI: 10.1097/fpc.0000000000000610 