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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19871 results in Negative / Null Result Report · page 425 of 663

Negative / Null Result ReportMedicine

Neuromuscular and Subjective Recovery Responses to Day and Night Fixtures During Congested and Noncongested Microcycles in Professional Soccer Players.

Mukandi I, Turner A, Bishop C et al. · 2026 · Journal of strength and conditioning research

Abstract Mukandi, I, Turner, A, Bishop, C, Beato, M. Neuromuscular and subjective recovery responses to day and night fixtures during congested and noncongested microcycles in professional soccer players. J Strength Cond Res XX(X):…

View details →DOI: 10.1519/jsc.0000000000005508
Negative / Null Result ReportMedicine

Influence of menstrual cycle phases on post-endodontic pain: a comparative clinical study with male patients.

Çıkman AŞ, Öksüzer MÇ, Hatipoğlu Ö et al. · 2026 · Odontology

Post-endodontic pain is a major concern that negatively impacts patients' quality of life. To date, there is no study examining the effect of the menstrual cycle on post-endodontic pain. Thus, this study aimed to elucidate any significant…

View details →DOI: 10.1007/s10266-026-01410-7
Negative / Null Result ReportMedicine

More pronounced effects of the extent of discectomy over the extent of laminectomy on postoperative biomechanics and clinical outcomes in unilateral biportal endoscopy for lumbar disc herniation.

Wang F, Wang T, Lu G et al. · 2026 · Journal of orthopaedic surgery and research

Background Unilateral biportal endoscopy (UBE) can be performed to treat lumbar disc herniation (LDH). Nevertheless, the postoperative clinical outcomes and spinal biomechanical implications following partial discectomy and laminectomy,…

View details →DOI: 10.1186/s13018-026-06955-5
Negative / Null Result ReportOpen accessMedicine

Radiofrequency Fields at 2.45 GHz Reprogram Mitochondria-Lysosome Crosstalk and Modulate the Survival/Death of Macrophages Exposed to LPS and/or the SARS-CoV-2 Spike Protein.

Sueiro-Benavides RA, Leiro-Vidal JM, Rodríguez-González JA et al. · 2026 · International journal of molecular sciences

The redox mechanisms of RAW 264.7 macrophages exposed to 2.45 GHz RF-EMF at subthermal specific absorption rates and to lipopolysaccharide (LPS) and/or the SARS-CoV-2 spike protein (CSP) were investigated. To this end, cellular responses…

View details →DOI: 10.3390/ijms27093813
Negative / Null Result ReportOpen accessMedicine

Toxicological Relevance of Biogenic Amines in Honey: Dietary Exposure and Integrated Risk Indicators in Algerian and Moroccan Honeys.

Bruno F, Bruschetta G, Miller A et al. · 2026 · Foods (Basel, Switzerland)

Biogenic amines are nitrogenous compounds that may occur in foods through plant metabolism, bee enzymatic activity, or microbial decarboxylation. This study evaluated biogenic amines content in monofloral honeys from Algeria and Morocco,…

View details →DOI: 10.3390/foods15081411
Negative / Null Result ReportMedicine

[Analysis of the prevalence characteristics and trends of allergen-specific IgE levels in a children's hospital in Wuhan City from 2019 to 2024].

Liu YH, Du Q, Zhang MR et al. · 2026 · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]

Objective: To investigate the changes in the positive rate of specific immunoglobulin E (sIgE) for inhalant and ingestive allergens in children at a certain children's hospital in Wuhan City from 2019 to 2024, and to analyze the…

View details →DOI: 10.3760/cma.j.cn112150-20250828-00834
Negative / Null Result ReportMedicine

Local Delivery of Tranexamic Acid and Dexamethasone via Piezoelectric Irrigationin Rhinoplasty: A Prospective Double-Blind Comparative Study of Early Postoperative Morbidities.

Gunay G, Ece M, Beloglu Tonyali Y et al. · 2026 · The Journal of craniofacial surgery

This study aimed to evaluate the effects of adding tranexamic acid (TXA) and dexamethasone to the irrigation solution of a piezoelectric device during open rhinoplasty on postoperative periorbital edema, ecchymosis, and pain. In this…

View details →DOI: 10.1097/scs.0000000000012827
Negative / Null Result ReportOpen accessMedicine

Microscopic and computational analysis of the stomach, duodenum, and liver of rats with induced hyperprolactinemia treated with exogenous melatonin.

da Silva JV, da Silva RC, Ferreira RGDS et al. · 2026 · Frontiers in veterinary science

Introduction This study evaluated the effects of exogenous melatonin (MEL) on morphological and computational alterations in the stomach, duodenum, and liver of hyperprolactinemic rats. Methods Twenty-four animals were divided into three…

View details →DOI: 10.3389/fvets.2026.1709295
Negative / Null Result ReportMedicine

Assessment of Plant and Soil Heavy Metal Pollution in an Abandoned Mining Area in Türkiye.

Hüseyinova R, Kutbay HG, Basançelebi O et al. · 2026 · Bulletin of environmental contamination and toxicology

This study was conducted in the northeast of Türkiye in an abandoned mine area. There were significant differences between study sites with respect to all heavy metals in the leaves of tree species. Statistically significant differences…

View details →DOI: 10.1007/s00128-026-04248-5
Negative / Null Result ReportMedicine

The application of internal ring closure in laparoscopic transabdominal preperitoneal (TAPP) repair for large indirect inguinal hernias: a retrospective study of 162 cases.

Liu M, Shen X · 2026 · Langenbeck's archives of surgery

Purpose Patients with primary unilateral indirect inguinal hernias and large internal inguinal rings have a higher incidence of seroma formation following laparoscopic transabdominal preperitoneal (TAPP) hernia repair. This study aims to…

View details →DOI: 10.1007/s00423-026-04102-6
Negative / Null Result Report

The effect of freeze-drying and storage on lactobacilli strains isolated from the gastrointestinal tract of wild boars using different cryoprotectants

Kavanova K, Babak V, Crhanova M · 2026 · Preprint

Abstract Probiotics play an important role in maintaining gastrointestinal comfort and health in piglets. For this reason, lactobacilli isolated from the gastrointestinal tract of domestic pigs and wild boars are evaluated for probiotic…

View details →DOI: 10.21203/rs.3.rs-9480160/v1
Negative / Null Result ReportMedicine

Acetabular cup orientation differs across surgical approaches in primary total hip arthroplasty: a retrospective analysis.

Chimeno-Pigrau C, Fernández-Valencia JA, Alías A et al. · 2026 · International orthopaedics

Purpose Accurate acetabular cup positioning is crucial in primary total hip arthroplasty (THA), as malposition is associated with instability and early failure. We hypothesized that acetabular cup orientation may differ according to the…

View details →DOI: 10.1007/s00264-026-06873-5
Negative / Null Result ReportOpen accessMedicine

Psychostimulant effects on motor and cognitive function in adults attention deficit hyperactivity disorder.

Cundari M, Kanold L, Bergwall D et al. · 2026 · The international journal of neuropsychopharmacology

Objectives This study aims to compare the performance on motor and cognitive functions of adult patients with attention deficit hyperactivity disorder (ADHD) with or without psychostimulant medication and controls. A secondary objective is…

View details →DOI: 10.1093/ijnp/pyag013
Negative / Null Result ReportOpen accessMedicine

Does alignment with Roussouly classification improve outcomes in well-aligned adult spinal deformity patients?

Kaghazchi A, Karnati J, Ashraf A et al. · 2026 · Surgical neurology international

Background Correction of adult spinal deformity (ASD) using the Roussouly classification, SRS-Schwab classification, or the global alignment and proportion (GAP) score is associated with reduced mechanical complications. However, the…

View details →DOI: 10.25259/sni_404_2026
Negative / Null Result ReportOpen accessMedicine

Effects of fermented palm kernel cake on growth performance, intestinal health, cecal microbiota, and ammonia emission in broilers.

Li J, Chen Z, Huang R et al. · 2026 · Poultry science

This study was conducted to evaluate the effects of fermented palm kernel cake (FPKC) on growth performance, intestinal health, cecal microbiota, nitrogen metabolism, and ammonia emission reduction of broiler chickens. A total of 900…

View details →DOI: 10.1016/j.psj.2026.107162
Negative / Null Result ReportMedicine

Obstetric and perinatal outcomes in twin pregnancies conceived through assisted reproduction: A retrospective cohort study.

Izbizky GH, Sevillano G, Abramor RM et al. · 2026 · Archivos argentinos de pediatria

Introduction. Multiple pregnancies are more frequently associated with adverse maternal and neonatal outcomes. The incidence of multiple pregnancies has increased with the use of assisted reproductive technologies (ART): they account for…

View details →DOI: 10.5546/aap.2025-10997.eng
Negative / Null Result ReportMedicine

Feasibility of Capillary Self-Collected Blood Specimens for Routine Outpatient Laboratory Testing.

Swartchick CB, Gurudu R, Lexvold NS et al. · 2026 · The journal of applied laboratory medicine

Background Capillary self-collection (CSC) devices allow patients to collect blood samples at home, potentially reducing outpatient phlebotomy visits. This study aimed to (a) assess the patient experience with multiple commercially…

View details →DOI: 10.1093/jalm/jfag075
Negative / Null Result ReportMedicine

[Experience of glutamine in parenteral nutrition in patients undergoing hematopoietic stem cell transplantation].

Alonso Domínguez MªT, Sánchez Navarro E, López López MJ et al. · 2026 · Nutricion hospitalaria

Introduction Introduction: hematopoietic stem cell transplantation (HSCT) is an aggressive and toxic procedure that can lead to malnutrition in patients. It has been proposed that these conditions may worsen under conditions of glutamine…

View details →DOI: 10.20960/nh.06172
Negative / Null Result ReportOpen accessMedicine

Variations in Pulse-Oxygen Saturation and Physical Development within the First 2 Hours after Birth Among Healthy Term Neonates Different Altitudes.

Du K, Yang YL, Li GY et al. · 2026 · Physiological research

This study aimed to examine early postnatal changes in pulse oxygen saturation (SpO2) and physical growth parameters during the first 2 hours following birth among healthy term neonates born at varying altitudes. A total of 963 healthy…

Negative / Null Result ReportMedicine

Effectiveness, Sex Differences, and Patient Experience in Real-World Use of Long-Acting Cabotegravir and Rilpivirine: Results from a Prospective Study.

González-Cordón A, Calvo J, Berrocal L et al. · 2026 · Infectious diseases and therapy

Introduction Long-acting intramuscular cabotegravir plus rilpivirine (LA-CAB/RPV) administered every 2 months (Q2M) has been available in Spain since January 2023 as a switch strategy for HIV treatment. We evaluated characteristics,…

View details →DOI: 10.1007/s40121-026-01373-w
Negative / Null Result Report

Feasibility study of dose calculation based on contrast-enhanced computed tomography for stereotactic body radiation therapy of lung metastases treated with MR-Linac

Zhao G, Liu M, Liu Y et al. · 2026 · Preprint

Abstract Background The reliability of contrast-enhanced CT (CHCT) as a reference image for MR-based dose calculation in lung stereotactic body radiation therapy (SBRT) with MR-Linac remains uncertain due to contrast-induced electron…

View details →DOI: 10.21203/rs.3.rs-9357535/v1
Negative / Null Result ReportMedicine

The role of gender in patients with developmental dysplasia of the hip treated with closed reduction and spica cast immobilization: does it affect prognosis?

Kang Z, Li Y, Canavese F et al. · 2026 · Journal of pediatric orthopedics. Part B

To investigate the impact of gender on the prognosis of children with developmental dysplasia of the hip (DDH) treated with closed reduction and spica cast immobilization (CR-SCI). A retrospective analysis was conducted on 302 DDH children…

View details →DOI: 10.1097/bpb.0000000000001343
Negative / Null Result ReportOpen accessMedicine

Secretoneurin as a novel predictor of metabolic syndrome in patients with obstructive sleep apnea syndrome.

Arslan İ, Aslan Y, Arı M et al. · 2026 · Brazilian journal of otorhinolaryngology

Objective This study aimed to evaluate whether Secretoneurin (SN) was elevated in Metabolic Syndrome (MetS) and could serve as a potential predictive biomarker in the development of MetS in patients with Obstructive Sleep Apnea Syndrome…

View details →DOI: 10.1016/j.bjorl.2026.101856
Negative / Null Result ReportMedicine

The Effectiveness and Safety of Robotic-Assisted Bronchoscopy Across Diverse Patient Heights: A Subset Analysis of a Multicenter, Prospective, Observational Trial.

Gomes C, Gomes C, Cowan B et al. · 2026 · Journal of bronchology & interventional pulmonology

Background Outcomes of robotic-assisted bronchoscopy (RAB) in patients of small stature remain uncertain due to concerns about their potentially smaller lung volumes. We assess the effectiveness and safety of RAB across height variations.…

View details →DOI: 10.1097/lbr.0000000000001075
Negative / Null Result ReportMedicine

AI-assisted radiomics for classification of benign and non-benign right heart masses in 2D-echocardiography.

Chen Y, Deng M, Xie L et al. · 2026 · Journal of translational medicine

Background The rarity of right heart masses challenges diagnostic proficiency, while reproducibility is affected by the echocardiography operator. Artificial intelligence (AI)-based imaging tools may help address these limitations. Methods…

View details →DOI: 10.1186/s12967-026-08322-8