A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20253 results in Negative / Null Result Report · page 424 of 676
Collins SF, Soliz L, Tucker G et al. · 2025 · Science of the Total Environment
Here, we assessed patterns of microplastics (MP; particles <5 mm) and microfibers (MF; fibers <5 mm) within benthic macroinvertebrates and fishes collected from a polluted urban stream (10-km segment; n = 5 reaches; 200-m reach lengths).…
Akiyama H, Sasaki Y, Tago K et al. · 2025 · Agriculture, Ecosystems and Environment.
Previous studies have reported that nitrification inhibitors are effective in reducing nitrous oxide emissions. However, no studies have reported the effectiveness of 3,4-dimethylpyrazole phosphate, and 3,4-dimethylpyrazole succinic acid…
Vavricka SR, Zeitz J, Madanchi M et al. · 2025 · The American journal of gastroenterology
Introduction Retrospective data suggest association of high-altitude exposure and inflammatory bowel disease flares. Knowledge about underlying pathogenesis remains limited. Methods This prospective interventional trial evaluated the…
Hammett JF, Kirwan M, Chen W · 2026 · Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors
Objective Intimate partner violence (IPV) is a major public health concern. Heavy episodic drinking (HED; i.e., drinking 5+ drinks for men or 4+ drinks for women in a 2-hr period) is a contributing cause of IPV, yet HED does not elicit IPV…
Savran F, Bayram F, Küçük F · 2026 · The Journal of craniofacial surgery
Objective This study aimed to evaluate the effects of intravenous dexamethasone and tranexamic acid (TXA), used alone and in combination, on perioperative bleeding and postoperative edema and ecchymosis in rhinoplasty. Methods In this…
Lipps KM, Samuel AM, Patel D et al. · 2025 · Journal for healthcare quality : official publication of the National Association for Healthcare Quality
Background Hypertension (HTN) is common in the inpatient setting, with many patients receiving as-needed (PRN) antihypertensive medications (anti-HTN) despite lack of benefit and risk of adverse events. We aimed to decrease PRN anti-HTN…
Shishimi G, Akaishi R, Matsukami M · 2025 · Preprint
Mirror self-recognition (MSR) is a key indicator of self-awareness, primarily studied in vertebrates. Investigating MSR in invertebrates such as the western honeybee ( Apis mellifera ), an insect with advanced cognition, is essential to…
Kato K, Honda Y, Kamatani T et al. · 2026 · Arthritis & rheumatology (Hoboken, N.J.)
Objective Cryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory disease caused by gain-of-function mutations in NLRP3. Although somatic NLRP3 mosaicism is increasingly recognized, it remains unclear how variant allele…
Demeckova V, Demcakova V, Sedlakova-Kadukova J · 2025 · IEEE transactions on nanobioscience
Silver nanoparticles (AgNPs) are widely used for their antimicrobial properties but pose risks like environmental contamination and potential harm to human health. Nanoparticles' small size facilitates translocation within the body, often…
Shaik NF, Denison L, Venezia GMA et al. · 2026 · Journal of hospital medicine
Background Hospitalized patients often experience poor sleep, which is associated with worse health outcomes, increased rates of delirium, and readmissions. Objective To improve overnight sleep for clinically stable general neurology…
Zhang J, Wu Q, Chi D et al. · 2025 · Soil & tillage research
Phosphorus-loaded iron-modified biochar (Fe-BP) can be used as farmlands' slow-release phosphorus (P) fertilizer. This study aimed to explore the effects of Fe-BP on soil P composition, phosphatase activity, peanut P accumulation, and P…
Lukyanov AN, Vargin PN, Yushkov VA · 2025 · Atmospheric research
The eruption of the underwater volcano Hunga Tonga – Hunga Ha'apai (20.54° S, 178.3° W) on January 15, 2022, resulted in the first significant increase in the stratospheric water vapor content in the entire satellite observation era. This…
Ackermann DM, Medcalf E, Bracken K et al. · 2026 · Journal of clinical epidemiology
Objectives Digital reminders are widely used in clinical trials, but their design is rarely evidence-based. We evaluated the effectiveness of two types of digital reminders for trial task completion. Study design and setting This…
Hadi CE, Dailaty AA, Sobh AH et al. · 2025 · Preprint
Abstract Background Postoperative pulmonary complications (PPCs) remain a major determinant of morbidity after noncardiac surgery. Whether prior SARS-CoV-2 infection independently heightens PPC risk in the contemporary, highly vaccinated,…
Jones PAT, Brockwell E, Hassan A et al. · 2025 · British journal of sports medicine
Objective Recreational and elite athletes report avoiding breastfeeding when returning to physical activity following childbirth due to a perceived increased risk of injury; yet, there are no empirical data to support this relationship. We…
Sadowska-Klasa A, Bełdzińska-Gądek K, Klein-Awerjanow K et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Objectives Cytomegalovirus (CMV) pneumonia is a serious complication in immunocompromised patients, but its role in non-transplant populations remains unclear. Methods We analyzed CMV DNA in bronchoalveolar lavage (BAL) samples from 100…
Wöhner S, Jescheniak JD · 2025 · Preprint
The production of a word is delayed by the recent production of one or more semantically related words. This phenomenon, known as semantic interference, has been observed in picture naming tasks involving either large sets of pictures…
Murray RL, Baldwin D, Brain K et al. · 2026 · Thorax
Introduction Lung cancer screening (LCS) with low-dose CT offers a teachable moment for smoking cessation (SC), but the optimal way to implement SC within LCS is unclear. The Yorkshire Enhanced Stop Smoking (YESS) study assessed the…
Garrido-Bautista J, Ortega Z, Pérez-Jiménez A et al. · 2025 · Ecological and evolutionary physiology
AbstractClutch size variation may be adaptive in bird populations if parents lay a clutch size that maximizes offspring recruitment. Brood size manipulation experiments allow for testing the optimization of clutch size by studying the…
Brown N, King SW, Bagshaw O et al. · 2026 · Injury
Introduction The Ilizarov method is an established technique for complex cases. Decisions about circular frame removal are imprecise, with no fully reliable method to confirm union. Errors can lead to complications such as refracture,…
Nie C, Zhong H, Shi H et al. · 2026 · Food chemistry
This study evaluated the effects of sodium substitutes (KCl, MgCl 2 , and CaCl 2 ) and soybean dietary fiber (SDF) on the textural, sensory, digestive, and storage properties of emulsion sausages. Replacing 25 % of NaCl with KCl or MgCl 2…
Feng Y, Liu Y, Ding X et al. · 2026 · The Journal of nutritional biochemistry
Alcohol-related liver disease is accompanied by hepatic zinc deficiency. We synthesized a zinc-glutathione (ZnGSH) complex as a zinc delivery system to test the hypothesis that effective zinc supplementation can recover the liver from…
Whitehead PS, Davis CP, Park JS et al. · 2025 · Journal of applied research in memory and cognition
Much research has focused on the language used for debunking false beliefs: communications should lead with facts, label misinformation as false, and reinforce true information. Pictures are used in debunking messages, but it remains…
Cartujano-Barrera F, Catley D, Chávez-Iñiguez A et al. · 2026 · Chest
Background Little is known about the use of text messages to promote enrollment in smoking cessation treatment. Research question What is the impact of the number of outreach messages and monetary incentives on enrollment in smoking…
Dumlu B, Bölükbaşi ŞC, Bayir A · 2026 · Lipids
We investigated molecular characteristics and tissue distribution of elongation of very long chain fatty acids (ELOVL) genes in the chicken (Gallus gallus) genome. The research specifically examines the expression levels of these genes in…
Barretto R, Sonnenfeld MM, da Silva RCM et al. · 2026 · Journal of robotic surgery
Objective To evaluate whether the use of intraoperative indocyanine green (ICG) fluorescence impacts anastomotic safety and surgical outcomes in patients undergoing bowel endometriosis resection. Methods Retrospective, multicenter…
Mihara A, Iwanaga R, Muramatsu K et al. · 2025 · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
Background Metastatic bone tumors in solid cancer often induce excessive local bone resorption leading to skeletal related events (SRE) which may impact patients' quality of life and survival of the primary cancer. Denosumab, a bone…
Weber MD, Frankenberger W, Ullman AJ et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Background Paediatric critically ill patients are at risk of harm from central venous catheter overuse. We applied an implementation science approach to promote appropriate use of midline catheters. The aim of this study was to evaluate…
Jones RW · 2025 · Potato Res..
Interest in phytomelatonin biosynthesis and activity has increased due to apparent effects on enhancing resistance to biotic and abiotic stress. Activity related to biotic stress has been associated with increased salicylic acid production…
Jensen K, Secher EL, Libermann RH et al. · 2025 · European clinical respiratory journal
Introduction The RheOx system delivers brief, high-voltage electrical pulses to the airway lining, promoting the regeneration of healthy tissue and reducing mucus production in COPD patients with chronic bronchitis. The procedure, called…