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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19871 results in Negative / Null Result Report · page 415 of 663

Negative / Null Result Report

Low Exercise Capacity Is Independent Of LVMI Despite Significant Change In Diastolic Function In Young non complicated Hypertensive Patients

Asaad Hasan Noaman, Oday Al- Salihi · 2019 · Al-Kufa University Journal for Biology

Systemic hypertension is common disease that affect many organs specially the cardiovascular system. Left ventricle hypertrophy is the main cardiac structural remodeling that occur in response to hypertension, furthermore. The role of LVM…

View details →DOI: 10.36320/ajb/v11.i1.8032
Negative / Null Result Report

Establishing Clinically Significant Change Benchmarks for the Moral Injury Outcome Scale in VA Behavioral Health Settings

Brett T. Litz, Hannah E. Walker, Luke Rusowicz-Orazem et al. · 2026 · Assessment

This study aimed to establish benchmarks for clinically significant change for the Moral Injury Outcome Scale (MIOS) using national data from Veterans treated in U.S. Department of Veterans Affairs (VA) behavioral health settings. We…

View details →DOI: 10.1177/10731911261436687
Negative / Null Result Report

Climate Change As a Significant Factor to the Aggravation of Coronary Artery Disease Among Elderly: A Basis for Emphasizing Community-based Self-care Measures

Eladio Martin Gumabay, Karen Mae Alcantara, Jaylord Ugaddan et al. · 2023 · Sudan Journal of Medical Sciences

Background: This research study explored the lived experience of the elderly with coronary artery disease (CAD) relevant to the effects of climate change as a basis for enhanced and strengthened community-based self-care measures. Methods:…

View details →DOI: 10.18502/sjms.v18i2.13599
Negative / Null Result Report

No significant change of extracranial conduit vessel diameter during cerebral vasomotor reactivity test with moderately‐altered end‐tidal CO 2

Jie Liu, Thuy Tien Cao Le, Allan Knox et al. · 2019 · The FASEB Journal

Cerebral vasomotor reactivity (CVMR) is often assessed using transcranial Doppler (TCD) to measure the cerebral blood flow velocity (CBFV) in the middle cerebral artery (MCA). Recently the validity of this technique has been questioned…

View details →DOI: 10.1096/fasebj.2019.33.1_supplement.528.12
Negative / Null Result Report

After-discharge activity as a basis to change intraoperative mapping protocol for functionally significant brain areas

M. G. Podgurskaya, D. S. Kanshina, A. V. Dimertsev et al. · 2023 · Epilepsy and paroxysmal conditions

Background. After-discharge (AD) activity is a pattern that differs from background corticography, represented by rhythmic stereotypical slow waves and/or repetitive spike discharges with ≥1 Hz frequency, recorded after cessation of…

View details →DOI: 10.17749/2077-8333/epi.par.con.2023.133
Negative / Null Result Report

29 Quick-Reference Criteria for Identifying Clinically Significant Multivariate Change in Older Adult Cognition: An ADNI Study

Jeremy G Grant, Amanda M Wisinger, Glenn E Smith · 2023 · Journal of the International Neuropsychological Society

Objective: Accurately interpreting change in cognitive functioning is an essential aspect of clinical care for older adults. Several approaches to identifying ‘true’ cognitive change in a single cognitive measure are available (e.g.,…

View details →DOI: 10.1017/s1355617723004678
Negative / Null Result Report

“There Is a Significant Change!” But Have They Noticed? A Case Study of Perceived Coaching Behaviour After Participating in the Growth Talent Mindsets for Sports Coaches’ Intervention 2.0

Dag André Nilsen, Lars Bjørke, Anne Marte Pensgaard et al. · 2026 · International Sport Coaching Journal

To help coaches create positive training environments, coach education programmes that include behaviour change techniques have been requested. Drawing on mindset theory and the development of wise psychological interventions, the Growth…

View details →DOI: 10.1123/iscj.2025-0096
Negative / Null Result ReportMedicine

Blood parasite infection is associated with lower thermoregulatory precision in the lizard Podarcis lusitanicus.

Faria, Megía-Palma, Whiting et al. · 2026 · Journal of thermal biology

Parasites have the potential to disrupt and induce changes in thermoregulation and behaviour in ectotherm hosts, possibly with deleterious effects. In a previous study, the lizard Podarcis lusitanicus (Lacertidae), when infected with blood…

View details →DOI: 10.1016/j.jtherbio.2026.104514
Negative / Null Result Report

3 Quick-Reference Criteria for Identifying Clinically Significant Multivariate Change in Older Adult Cognition: A NACC Study

Amanda M. Wisinger, Hillary F. Abel, Jeremy G. Grant et al. · 2023 · Journal of the International Neuropsychological Society

Objective: Accurately interpreting cognitive change is an essential aspect of clinical care for older adults. Several approaches to identifying 'true’ cognitive change in a single cognitive measure are available (e.g., reliable change…

View details →DOI: 10.1017/s1355617723010858
Negative / Null Result Report

Calculation of the Least Significant Change Value of Bone Densitometry Using a Dual-Energy X-ray Absorptiometry System

Han-Kyung Seo, Do-Cheol Choi, Cheol-Min Shim et al. · 2023 · Korean Journal of Nuclear Medicine Technology

Purpose: The precision error of a bone density meter reflects the equipment and reproducibility of results by an examiner. Precision error values can be expressed as coefficient of variation (CV), CV%, and root mean square-SD (RMS-SD). The…

View details →DOI: 10.12972/kjnmt.20230015
Negative / Null Result Report

Abstract 227: Long Term Outcomes In Patients With Type 2 Myocardial Infarction With And Without Significant Change In Troponin Levels

Christopher Jenkins, Tamunoinemi Bob-Manuel, Jayna Kelly et al. · 2022 · Circulation: Cardiovascular Quality and Outcomes

Background: It is well known that morbidity and mortality are higher in patients with Type 2 Myocardial Infarction (T2MI) compared to Type 1 MI. Few studies have compared outcomes in T2MI patients with significant increase in troponins…

View details →DOI: 10.1161/circoutcomes.15.suppl_1.227
Negative / Null Result Report

P-1753. Impact of a Microbiology Reporting Change on Treatment Selection and Clinical Outcomes for Organisms at Low-Risk for Significant AmpC Production

Ellie Hodapp, Patrick M Kinn, Bradley A Ford et al. · 2025 · Open Forum Infectious Diseases

Abstract Background AmpC β-lactamase production can be induced after exposure to beta lactam antimicrobials, most notably ceftriaxone (CRO), leading to development of resistance on therapy. New guidance from IDSA indicates that the risk of…

View details →DOI: 10.1093/ofid/ofae631.1916
Negative / Null Result Report

The Significant Correlation between Self Efficacy and the Role of Islamic Education Teachers as a Society Change Agent

Noornajihan Jaafar, Nurul Asia Fasehah Muhamad, Ab. Halim Tamuri et al. · 2019 · Mediterranean Journal of Social Sciences

Abstract The role of Islamic education teacher (IET) as society change agent (SCA) requires a strong internal motivation factor. It begins with confidence in self-ability i.e. self-efficacy (SE) in implementing the trust given to them.…

View details →DOI: 10.2478/mjss-2019-0044
Negative / Null Result Report

Significant Temperature Change and Inhomogeneous Tensile Deformation of Superelastic Ti–26Nb, Ti–25Nb–0.3O and Ti–25Nb–0.3N Shape Memory Alloys

Karol Marek Golasiński, Michał Maj, Sandra Musiał et al. · 2025 · Metallurgical and Materials Transactions A

Abstract In this work, thermomechanical behavior of the superelastic Ti–26Nb, Ti–25Nb–0.3O and Ti–25Nb–0.3N (at. pct) shape memory alloys (SMAs) under load-unload tension was investigated using coupled techniques of infrared thermography…

View details →DOI: 10.1007/s11661-025-08036-4
Negative / Null Result Report

Risk Factors at Time of Primary ACL Reconstruction that Contribute to Significant Chondral Surface Change at Time of Revision ACL Reconstruction

Christopher C. Kaeding, Mars Group · 2016 · Orthopaedic Journal of Sports Medicine

Objectives: Articular cartilage health is an important issue following primary anterior cruciate ligament reconstruction (ACLR). It is not clear what risk factors at the time of primary reconstruction affect future articular cartilage…

View details →DOI: 10.1177/2325967116s00199
Negative / Null Result Report

ABSTRACT NUMBER: ESOC2026A2329 CHANGE IN CEREBRAL HEMODYNAMIC PARAMETERS IN PATIENTS WITH OBESITY EXPERIENCING SIGNIFICANT WEIGHT LOSS. THE HEM-OB STUDY

M Teresa Montalvo Moraleda, Álvaro Bonelli Franco, Tamara Díaz Vico et al. · 2026 · European Stroke Journal

Abstract Background and aims The relationship of obesity with small vessel disease remains controversial. The HemOb study aims to evaluate hemodynamic and functional parameters in patients with obesity undergoing bariatric surgery and…

View details →DOI: 10.1093/esj/aakag023.1069
Negative / Null Result Report

Dampak Sosial Ekonomi pada Keluaga Penerima Manfaat (KPM) Program Keluarga Harapan (PKH) Exit Mandiri di Kecamatan Pagelaran Kabuoaten Pringsewu dalam Perspektif The Most Significant Change Technique (MSCt)

Ainun Oktavia Sari, Rahayu Sulistyowati, Ita Prihantika · 2020 · Administrativa: Jurnal Birokrasi, Kebijakan dan Pelayanan Publik

The Conditional Cash Transfer (CCT) is a conditional social cash transfer program that provides assistance to Very Poor Households (RTSM) appointed as participants in the Conditional Cash Transfer program which is related to improving the…

View details →DOI: 10.23960/administrativa.v2i3.51
Negative / Null Result Report

Abstract 17917: Is Small Change Significant? Association of Small Differences in Life's Simple 7 and Mortality: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort

Mary Cushman, Suzanne E Judd, Virginia J Howard et al. · 2011 · Circulation

Background. The AHA 2020 Goal includes improving cardiovascular health, defined using a metric consisting of 7 health factors, Life's Simple 7. A central concept of the goal is that small improvements in behavior / lifestyle factors at the…

View details →DOI: 10.1161/circ.124.suppl_21.a17917
Negative / Null Result Report

Comparison of screen-confirm versus screen-mix-confirm algorithms for lupus anticoagulant detection by dilute Russell’s viper venom time

Fatima Sharif, Ayesha Junaid, Khadija Ashraf · 2025 · Journal of Laboratory Physicians

Objectives Lupus anticoagulant (LAC) is an antiphospholipid antibody associated with thromboembolism. According to the International Society on Thrombosis and Haemostasis, LAC measurement by Dilute Russell’s viper venom time (dRVVT) should…

View details →DOI: 10.25259/jlp_110_2024
Negative / Null Result ReportMedicine

Olfactory notes in the mind space: A registered report.

Caldana M, Rusconi E · 2026 · Cortex; a journal devoted to the study of the nervous system and behavior

Olfaction is an archaic sense but its central mechanisms are lesser known than those of other senses. Here we address a possible link between olfactory stimuli and mental spatial representations. Although olfactory percepts are not…

View details →DOI: 10.1016/j.cortex.2026.02.010
Negative / Null Result Report

The investigative methodology to confirm Alcohol consumption in all suspects at a tertiary care Hospital at Karachi

Dr. Iqbal Ahmed Khan, Dr. Mir Ghulam Ali Talpur, Dr. Naved Ali Qadri et al. · 2020 · ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE

Background: Various health problems occur due to alcohol consumption and particularly heavy drinking which contributes to a major burden of diseases globally.
 
 Objective: To identify the investigative methodology carried out by…

View details →DOI: 10.58397/ashkmdc.v25i3.262
Negative / Null Result Report

Troy III-V

Donald Easton, Bernhard Weninger · 2023 · Documenta Praehistorica

To investigate the dating of Troy III-V, and in particular to test whether in Blegen's Troy sequence a gap exists between Troy III and Troy IV, 26 bone samples covering Troy III to VIa from the University of Cincinnati excavations were…

View details →DOI: 10.4312/dp.50.14
Negative / Null Result Report

Experiments on the hydrodynamic performance of horizontal axis marine current turbines to confirm computational predictions

Navneet Kumar Vishnoi · 2021 · Asian Journal of Multidimensional Research

Converting the kinetic energy provided by ocean or marine currents is an intriguing prospect since it may provide a consistent and predictable energy source. The bulk of the suggested designs for converting this kind of kinetic energy are…

View details →DOI: 10.5958/2278-4853.2021.01079.x