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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19866 results in Negative / Null Result Report · page 394 of 663

Negative / Null Result ReportOpen accessMedicine

The Variability and Determinants of Serotiny in <i>Pinus Yunnanensis</i>.

Liu Y, Lin H, Yu D et al. · 2026 · Ecology and evolution

Serotiny, a key fire-adaptive trait, enables certain plants to retain seeds in closed cones until triggered by fire, thus facilitating post-fire regeneration. Although serotiny has been observed in many species, the physiological and…

View details →DOI: 10.1002/ece3.72838
Negative / Null Result ReportOpen accessMedicine

Does Pain Self-efficacy influence Initial Forward Bending in Adults with Chronic Low Back Pain following Exercise? A Cohort Study.

McManus F, Pranata A, Simpson JA et al. · 2025 · International journal of sports physical therapy

Background/purpose Chronic low back pain affects how individuals bend. Whether pain self-efficacy, a term describing one's confidence in their ability to perform activities despite experiencing pain, affects how much people with chronic…

View details →DOI: 10.26603/001c.146051
Negative / Null Result ReportOpen accessMedicine

Woody seeds and seedlings are unresponsive to herbivore kairomones.

Headrick KC, Pellegrini BA, Santiago EM et al. · 2026 · AoB PLANTS

Herbivory is particularly threatening to young plants that lack the resources needed to survive an attack. Seeds and seedlings should thus benefit greatly from using pre-attack cues to induce defence before damage. Locomotion mucus from…

View details →DOI: 10.1093/aobpla/plag013
Negative / Null Result ReportOpen accessMedicine

Does civilian oversight impact police legitimacy?

Schiff KJ, Schiff DS, Moy BJ et al. · 2025 · PNAS nexus

Does the implementation of external oversight in policing improve public perceptions of police legitimacy? Civilian review boards (CRBs) are frequently promoted as mechanisms to enhance the legitimacy of police agencies by providing…

View details →DOI: 10.1093/pnasnexus/pgaf267
Negative / Null Result ReportOpen accessMedicine

Magnetic Seizure Therapy vs Electroconvulsive Therapy in Schizophrenia: Prefrontal-Amygdala Plasticity and Cognitive Safety.

Li J, Jin T, Chi Y et al. · 2025 · Neuropsychiatric disease and treatment

Purpose Reducing electroconvulsive therapy (ECT)'s cognitive burden without compromising efficacy is critical. Although magnetic seizure therapy (MST) shows comparable symptom remission in schizophrenia, its neuroanatomical…

View details →DOI: 10.2147/ndt.s531892
Negative / Null Result ReportOpen accessMedicine

Further evidence that averageness and femininity, rather than symmetry and masculinity, predict facial attractiveness judgments.

Lee P, Li J, Rafiee Y et al. · 2025 · Scientific reports

Facial attractiveness influences important social outcomes and most studies investigating possible predictors of facial attractiveness have tested for effects of shape symmetry, averageness (i.e., the converse of distinctiveness), and…

View details →DOI: 10.1038/s41598-025-86974-0
Negative / Null Result ReportMedicine

Isokinetic shoulder strength adaptations to weighted jump rope training in CrossFit athletes: A pre-post study.

Torres-Banduc MA, Thapa RK, Pérez MA et al. · 2025 · Shoulder & elbow

Background The isokinetic shoulder profile is commonly used to assess injury risk in overhead sports. CrossFit athletes are vulnerable to shoulder injuries due to high-load, high-repetition demands. This exploratory study aimed to evaluate…

View details →DOI: 10.1177/17585732251409407
Negative / Null Result ReportOpen accessMedicine

Infants Do Not Reliably Track When Bilingual Speakers Switch Languages.

Potter CE, Lew-Williams C · 2025 · Behavioral sciences (Basel, Switzerland)

It is a widely held belief that bilingual infants benefit from hearing each of their languages spoken by different people, as speakers could serve as a cue for separating the two languages. However, it is not yet known whether infants…

View details →DOI: 10.3390/bs15101427
Negative / Null Result ReportOpen accessMedicine

Non-image-forming vision as measured through ipRGC-mediated pupil constriction is not modulated by covert visual attention.

Vilotijević A, Mathôt S · 2024 · Cerebral cortex (New York, N.Y. : 1991)

In brightness, the pupil constricts, while in darkness, the pupil dilates; this is known as the pupillary light response (PLR). The PLR is driven by all photoreceptors: rods and cones, which contribute to image-forming vision, and…

View details →DOI: 10.1093/cercor/bhae107
Negative / Null Result ReportOpen accessMedicine

The impact of state and trait general and social anxiety on theory of mind.

Foulds C, Khudiakova V, Surtees ADR · 2026 · Scientific reports

Theory of mind is an important skill to function in society. There is evidence that anxiety can impair the ability to use this skill effectively; however, current research is inconclusive, uses heterogeneous measures of theory of mind, and…

View details →DOI: 10.1038/s41598-026-36718-5
Negative / Null Result ReportOpen accessMedicine

Association between serum bilirubin and diabetic retinopathy: results from the NHANES 1999-2018 and Mendelian randomization study.

Niu D, Ye L, Gu X et al. · 2026 · Diabetology & metabolic syndrome

BACKGROUND: Although serum bilirubin levels have been linked to diabetic retinopathy (DR), their causal role remains uncertain. We aimed to assess the relationship between bilirubin levels and diabetic retinopathy (DR) using both…

View details →DOI: 10.1186/s13098-026-02135-x
Negative / Null Result ReportOpen accessMedicine

Comparison of oncological outcomes between wedge resection and segmentectomy for T1a/bN0M0 non-small-cell lung cancer: a population-based retrospective cohort study.

Zhang Z, Lian H, Huang L et al. · 2026 · International journal of surgery (London, England)

Background Sublobar resection, including wedge resection (WR) and segmental resection (SR) has been considered for early-stage non-small-cell lung cancer (NSCLC). However, the optimal sublobar approach continues to be a subject of…

View details →DOI: 10.1097/js9.0000000000003433
Negative / Null Result ReportOpen accessMedicine

No evidence that averaging voices influences attractiveness.

Ostrega J, Shiramizu V, Lee AJ et al. · 2024 · Scientific reports

Vocal attractiveness influences important social outcomes. While most research on the acoustic parameters that influence vocal attractiveness has focused on the possible roles of sexually dimorphic characteristics of voices, such as…

View details →DOI: 10.1038/s41598-024-61064-9
Negative / Null Result ReportOpen accessMedicine

Parietal theta burst TMS does not modulate bistable perception.

Schauer G, Grassi PR, Gharabaghi A et al. · 2024 · Neuroscience of consciousness

The role of the parietal cortex in perceptual awareness and in resolving perceptual ambiguity is unsettled. Early influential transcranial magnetic stimulation studies have revealed differences in conscious perception following parietal…

View details →DOI: 10.1093/nc/niae009
Negative / Null Result ReportOpen accessMedicine

The relationship between aging out of the special supplemental nutrition program for women, infants, and children assistance and weight status in kindergarten.

Lazic A, Thomsen MR, Brown CC et al. · 2025 · Preventive medicine reports

Objective The Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides access to nutritional resources to low-income children starting at birth through enrollment in kindergarten or turning five years old. The…

View details →DOI: 10.1016/j.pmedr.2025.103125
Negative / Null Result ReportMedicine

Name order effects in measuring adolescent social networks using rosters.

Liu S, Nolin DA, Kitts JA · 2024 · Social networks

Recent studies have found order effects in social network data collection, where later names on a roster receive fewer nominations. Some thus argue for randomizing name orders or sampling peer names for survey rosters. We model order…

View details →DOI: 10.1016/j.socnet.2023.07.002
Negative / Null Result ReportOpen accessMedicine

Biomechanical Factors Associated with Intraindividual Differences in Running Economy Across Advanced Footwear Technology Models in Long-Distance Runners.

Fohrmann D, Schaffarczyk M, Menge C et al. · 2026 · Sports medicine - open

Background Advanced footwear technology (AFT) can enhance long-distance running performance by improving running economy (RE). However, the range of the individual improvements is large. Different intra-individual responses in running…

View details →DOI: 10.1186/s40798-026-01005-0
Negative / Null Result ReportOpen accessMedicine

Exploring the Causal Links Between Toxoplasma gondii Infection and Risk of Brain Tumors: A Bidirectional Mendelian Randomization Analysis.

Shi P, Wei G, Li Z et al. · 2026 · Brain and behavior

Background Toxoplasma gondii (T. gondii) is a ubiquitous protozoan parasite capable of establishing lifelong latent infections in the central nervous system. Previous epidemiological studies have suggested a potential association between…

View details →DOI: 10.1002/brb3.71239
Negative / Null Result ReportOpen accessMedicine

Alterations of brain network topology and structural-functional connectivity coupling in noise-induced hearing loss based on macroscopic scale.

Wang A, Bao X, Wang C et al. · 2025 · Frontiers in neuroscience

Objective To investigate the changes in the global attributes of structural connectivity (SC) and functional connectivity (FC) graph theory, as well as the coupling topological structure of the whole brain SC-FC in patients with…

View details →DOI: 10.3389/fnins.2025.1661096
Negative / Null Result ReportOpen accessMedicine

Association of cardiovascular risk scores with coronary plaque and its progression among individuals with family history of coronary artery disease.

Soh CH, Nerlekar N, Whitmore K et al. · 2026 · American journal of preventive cardiology

Background Multiple cardiovascular (CV) risk assessment scores can predict CV events. The current trend towards assessing atheroma has led to these scores being used to identify patients who might benefit from coronary plaque imaging.…

View details →DOI: 10.1016/j.ajpc.2026.101423
Negative / Null Result ReportOpen accessMedicine

<i>TNF-α</i> rs1800629 Polymorphism in Vietnamese COPD Patients: Exploratory Evidence for Recessive Protective Association and Clinical Correlates.

Nguyen HM, Le DHH, Ho TTH et al. · 2026 · The application of clinical genetics

Background Chronic obstructive pulmonary disease (COPD) poses a significant health burden in Vietnam. The TNF-α rs1800629 (-308G/A) polymorphism is an influential factor in disease pathogenesis. However, its association is inconsistent…

View details →DOI: 10.2147/tacg.s586977
Negative / Null Result ReportOpen accessMedicine

Kava consumption and the rise of sociopolitical complexity in Oceania.

Hrnčíř V, Sheehan O, Claessens S et al. · 2026 · Proceedings of the National Academy of Sciences of the United States of America

Humans have been using psychoactive substances for millennia, despite their potential negative health and social consequences. According to some scholars, our craving for mind-altering drugs is an evolutionary mistake-a hijacking of our…

View details →DOI: 10.1073/pnas.2521658123
Negative / Null Result ReportOpen accessMedicine

Assessment of β-blocker use and all-cause mortality in patients with myocardial infarction: a real-world analysis of the NHANES 1999-2018 database.

Ling W, Li H, Liu L et al. · 2025 · Open heart

Objective To evaluate the association between β-blocker use and all-cause mortality in a real-world cohort of patients with myocardial infarction (MI). Methods This study included 2308 patients with MI from the National Health and…

View details →DOI: 10.1136/openhrt-2025-003757
Negative / Null Result ReportOpen accessMedicine

Post-Traumatic Headache in Children and Genetic Risk of Migraine: An Observational Cohort Study.

Orr SL, Hershey AD, Kurowski BG et al. · 2026 · Neurology. Genetics

Background and objectives To examine the association between genetic risk of migraine and post-traumatic headache (PTH) in children. Methods This is a secondary analysis of a cohort study that recruited children aged 8-17 years within 48…

View details →DOI: 10.1212/nxg.0000000000200371
Negative / Null Result ReportOpen accessMedicine

Mendelian randomization unveils genetic causal relationships between viral infections and systemic sclerosis.

Cheng T, Zhang HY, Wang TR et al. · 2025 · Scientific reports

This study uses Mendelian randomization (MR) to investigate the potential causal relationships between viral infections, including Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), SARS-CoV-2, cytomegalovirus (CMV), human…

View details →DOI: 10.1038/s41598-025-08361-z