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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

20240 results in Negative / Null Result Report · page 389 of 675

Negative / Null Result ReportOpen accessMedicine

Effects of Betaine on Performance, Blood Biochemistry, Nutrient Utilization and Gut Health in Coccidia-Infected Broilers.

Hafeez A, Saleem U, Naz S et al. · 2026 · Veterinary medicine and science

The objective of this study was to investigate the ameliorative effect of betaine on the performance, blood biochemistry, intestinal lesion score and nutrient utilization of broiler chickens exposed to coccidian challenge. A total of 600…

View details →DOI: 10.1002/vms3.70779
Negative / Null Result Report

Ethical Sensitivity and Moral Reasoning in Medical Students in Ecuador: Insights for Medical Education in Latin America

Moreira-Vera D, Solórzano MLP, Marín-Pérez AL · 2026 · Preprint

Abstract Introduction: Ethical decision-making is a core competency in medical training. However, evidence regarding moral reasoning and ethical sensitivity among medical students in Latin America remains limited, particularly in settings…

View details →DOI: 10.21203/rs.3.rs-9520858/v1
Negative / Null Result ReportMedicine

Inferior Vena Cava to Aorta Ratio in Children With Non-Hemorrhagic Shock After Fluid Bolus Using Point of Care Ultrasound.

Hamsika V, Batra P, Bhaskar V et al. · 2026 · Pediatric emergency care

Objective To compare IVC/Ao ratio, IVC collapsibility/distensibility indices before and after the administration of fluid bolus therapy in children with non-hemorrhagic shock using point of care ultrasound, and to correlate the changes in…

View details →DOI: 10.1097/pec.0000000000003626
Negative / Null Result ReportOpen accessMedicine

Engaging with Facebook Health Support Groups among Australian Culturally and Linguistically Diverse Populations.

Zein MMA, Win KT, Alananzeh I · 2026 · Healthcare informatics research

Objectives This study aims to explore the key factors that enhance engagement in Facebook health support groups among Australian culturally and linguistically diverse (CALD) communities. Methods A cross-sectional online survey was…

View details →DOI: 10.4258/hir.2026.32.1.14
Negative / Null Result ReportMedicine

Factors influencing the sensory profile in patients with autism spectrum disorder from 16 months to 14 years: results of an observational study.

Marani N, di Gennaro D, Garotti R et al. · 2026 · Frontiers in psychiatry

Introduction Sensory processing abnormalities represent a high-impact clinical feature in individuals with Autism Spectrum Disorder (ASD). Sensory alterations can be classified by modality and behavioral responses to stimuli. The…

View details →DOI: 10.3389/fpsyt.2026.1771832
Negative / Null Result ReportMedicine

Spondylolisthesis Reduction and Changes in Sagittal Alignment Following Single-Position Lateral Versus Lateral-Then-Prone Oblique Lumbar Interbody Fusion With Navigation-Assisted Posterior Percutaneous Instrumentation.

Ansari D, Bethel JA, Greeneway GP et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)

Background and objectives Lateral interbody fusion represents a minimally-invasive approach to achieve indirect decompression via disc height restoration and alignment correction in patients with degenerative lumbar spondylolisthesis. If…

View details →DOI: 10.1227/ons.0000000000002019
Negative / Null Result ReportMedicine

Evaluation of organosilicone surfactants as synergists of Solenopsis invicta virus 3 in Solenopsis invicta.

White RL, Read QD, Valles SM · 2026 · Journal of invertebrate pathology

Solenopsis invicta virus 3 (SINV3) is a biological control agent against the red imported fire ant, S. invicta. We attempted to improve the virus' effectiveness with organosilicone adjuvants hydroxy trisiloxane [hydroxyTSX] and methoxy…

View details →DOI: 10.1016/j.jip.2026.108573
Negative / Null Result ReportMedicine

Tunable self-association of partially dephosphorylated beta-casein

Rasmussen PL, Rinnan Å, Nielsen SB et al. · 2026 · Food Hydrocolloids.

The utilization of bovine casein for creating casein micelles with properties resembling those in human milk presents an opportunity to bridge the nutritional gap between human milk and infant formula. However, the processing of these…

Negative / Null Result ReportMedicine

No Significant Impact of Preoperative Electrodiagnostic Testing on Short-Term Outcomes after Carpal Tunnel Release.

Williams AJ, Pum JM, Deyoung JK et al. · 2026 · The journal of hand surgery Asian-Pacific volume

Background: The purpose of this study was to compare Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (UE) and PROMIS Pain Interference (PI) scores before and after carpal tunnel release (CTR) between…

View details →DOI: 10.1142/s2424835526500189
Negative / Null Result ReportMedicine

Mechanistic-statistical model for the expansion of ash dieback.

Fritsch C, Grosdidier M, Gégout-Petit A et al. · 2026 · Theoretical population biology

Hymenoscyphus fraxineus is an invasive forest fungal pathogen that induces severe dieback in European ash populations. The spread of the disease has been closely monitored in France by the forest health survey system which has made it…

View details →DOI: 10.1016/j.tpb.2026.06.006
Negative / Null Result Report

The Double-Edged Sword of Competition: How Organizational Effectiveness Mediates the Impact of Environmental Dynamism on SME Export Performance

Erfanikia A, Hajikarimi B, Nazari A et al. · 2026 · Preprint

Abstract This study investigates the complex interplay between strategic orientation, internal capabilities, and external environmental forces in shaping the export performance of Small and Medium-sized Enterprises (SMEs). Specifically, it…

View details →DOI: 10.21203/rs.3.rs-8924474/v1
Negative / Null Result ReportMedicine

Evaluating the Role of the Self-Assembling Topical Haemostat PuraBond in Periorbital Ecchymosis Associated with Osteotomies in Septorhinoplasty.

Rafay A, Beegun I, Joseph J · 2026 · Facial plastic surgery : FPS

Abstract Septorhinoplasty for both functional and cosmetic purposes is a widely performed operation. As with any surgical intervention, there are inherent risks that include bleeding manifesting as periorbital ecchymosis (PE). PuraBond is…

View details →DOI: 10.1055/a-2843-8884
Negative / Null Result ReportMedicine

Randomized communication nudges to increase primary care engagement among Medicaid enrollees in Maine.

Gordon SH, Nguyen KH, Biondi-Bonetti B et al. · 2026 · Health affairs scholar

Despite the importance of primary care in disease prevention, few studies have examined behavioral interventions to increase primary care engagement. In partnership with the Maine Department of Health and Human Services, we implemented a…

View details →DOI: 10.1093/haschl/qxag100
Negative / Null Result Report

Influence of Patient-Related Factors and Surgeon Experience on Functional Outcomes in Conservatively Treated Proximal Humerus Fractures: A Retrospective Cohort Study

Pautasso A, Bernardi C, Assom M et al. · 2026 · Preprint

Abstract Purpose Proximal humerus fractures (PHFs) are common in the elderly population, but the optimal treatment strategy remains controversial. This study evaluated long-term functional outcomes of conservatively treated PHFs and…

View details →DOI: 10.21203/rs.3.rs-9669363/v1
Negative / Null Result ReportMedicine

Depressive Symptoms, Social Support, and Health-Related Quality of Life of Patients After Lung Transplantation.

Fan CH, Chen WH, Chou YH et al. · 2026 · Transplantation proceedings

Background Lung transplant recipients often experience depressive symptoms that can negatively impact their health-related quality of life (HRQOL). This study examined the relationship between depression and HRQOL, and whether social…

View details →DOI: 10.1016/j.transproceed.2026.05.015
Negative / Null Result ReportMedicine

A Personal Experience of Buccal Flaps for Cleft Palate Repair and the Effect of Buccal Flaps on Dentition.

McCrossan S, Francis EC, Graham F et al. · 2026 · The Journal of craniofacial surgery

Objective To assess the effect of buccal mucosal flaps for cleft palate (CP) repair on dental hygiene and eruption of the posterior molar teeth. Design A retrospective review of CP patients between 2008 and 2015 from our prospective (live)…

View details →DOI: 10.1097/scs.0000000000013017
Negative / Null Result ReportOpen accessMedicine

Serological response to feline coronavirus in the UK domestic cat population.

Sasvari H, Sherry L, Logan N et al. · 2026 · The Journal of general virology

Feline coronavirus (FCoV) is a ubiquitous virus of cats, with highly variable seroprevalence, ranging between 4 and 95% worldwide in the domestic cat population. It is the causative agent of feline infectious peritonitis (FIP), a disease…

View details →DOI: 10.1099/jgv.0.002270
Negative / Null Result ReportMedicine

Association of Polymorphisms of Inflammatory-Relevant Genes with Cancer Risk.

AlSrayea S, Alrashid MH, Bastaki NK et al. · 2026 · Current issues in molecular biology

Colorectal cancer (CRC) and non-Hodgkin lymphoma (NHL) are among the most prevalent cancer types globally by incidence and mortality. Both types are influenced differentially by chronic inflammation. Central to this inflammation are…

View details →DOI: 10.3390/cimb48060548
Negative / Null Result ReportMedicine

Assessing the Effectiveness of Multidisciplinary Interventions in Reducing Catheter-Associated Urinary Tract Infection: An Interrupted Time Series Modeling Approach.

Wills W, Rosever K, Bugajski A et al. · 2026 · Journal of nursing care quality

Background Recommendations support multi-interventional catheter-associated urinary tract infection (CAUTI) reduction programs; however, identifying specific interventions with significant impact may be beneficial in resource-limited…

View details →DOI: 10.1097/ncq.0000000000000956
Negative / Null Result ReportMedicine

Exploring the Mediating Role of Social Media and Gaming in the Relationship between Adolescents' Feelings of Loneliness, Ostracism and Internalizing and Externalizing symptoms.

Bruneel S, Sjöblom J, Lagerström M et al. · 2026 · Child psychiatry and human development

Social outsiderhood - particularly loneliness and ostracism - has a significant impact on mental health issues such as internalizing symptoms (e.g., depression, anxiety) and externalizing symptoms (e.g., aggression, conduct problems). Yet,…

View details →DOI: 10.1007/s10578-026-02027-1
Negative / Null Result ReportMedicine

Local hemodynamic changes and branch outcomes associated with inner branched versus outer branched stent grafts.

Erhart P, Bresler AM, Peters AS et al. · 2026 · Annals of vascular surgery

Background This study compared the hemodynamic performance and branch outcomes of outer branched (t-Branch) and inner branched (E-nside) stent-graft designs. Methods Patient-specific computational fluid dynamics (CFD) simulations were…

View details →DOI: 10.1016/j.avsg.2026.06.027