A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19859 results in Negative / Null Result Report · page 381 of 662
Wamsley EJ, Barron J, Livingston WH · 2026 · Journal of cognitive neuroscience
Memory is consolidated during "offline" states of reduced attention to the external stimulus environment, including sleep and resting wakefulness. While consolidation is usually studied on a timescale of hours to days, accumulating…
Piazza FRG, Schuch JB, Ferreira DNSDS et al. · 2025 · Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
Objective N-acetylcysteine (NAC) is a medication known for its hepatoprotective properties and potential to reduce cravings and psychoactive substance use. Vitamin D is metabolized in the liver, and individuals with alcohol abuse often…
Chen PA, Hsueh YC, Lin YC et al. · 2026 · The Journal of arthroplasty
Background Whether the addition of magnesium sulfate (MgSO 4 ) to intra-articular analgesic cocktails improves early pain after total knee arthroplasty (TKA) remains uncertain. Methods This prospective, double-blind, within-patient…
Leak M, Giambini H, Cheever K et al. · 2026 · Journal of sport rehabilitation
Context Thoracic mobility is integral to respiratory function and mobility of the neck, shoulder, and spine. The efficacy of thoracic mobility exercises in enhancing respiratory function and spinal range of motion (ROM) is well documented…
Mayer J, Al-Sheikhli J, Wang X et al. · 2026 · JACC. Clinical electrophysiology
Background Functional extra-stimulus (ES) substrate mapping has been shown to reduce the recurrence of ventricular tachycardia (VT) compared with intrinsic rhythm mapping. However, there is no standardized approach to functional ES…
Mattila N, Meinberg M, Juppo A et al. · 2026 · Scandinavian journal of gastroenterology
Objective To assess whether a gargled articaine solution makes gastroscopy more tolerable for the patient. Background Gastroscopy is an unpleasant experience for most people. A drug that is easy to use, has a fast onset, enables quick…
Navarro LP, Combes X, Galinski M et al. · 2026 · BMC emergency medicine
Introduction We aimed to assess the relationship between arterial partial pressure of carbon dioxide (PaCO 2 ) and end-tidal carbon dioxide (EtCO 2 ) according to three prehospital hemodynamic status and to evaluate whether…
Jorritsma R, Bijkerk HJC, Martina R et al. · 2026 · Irish veterinary journal
In September 2023, the official national reference laboratory confirmed the presence of BTV serotype 3 in The Netherlands. In the following weeks, it appeared that the infection caused very severe clinical signs in sheep, but it was…
Burtnett SL, Bomberger RA, Harvatine KJ · 2026 · Journal of dairy science
Oleic acid has a lower risk for biohydrogenation-induced milk fat depression (MFD) than linoleic acid and can act as an emulsifier to aid fatty acid (FA) digestion in the small intestine. Our objective was to evaluate the effect of high…
Alachkar MN, Schlegl J, Bannehr M et al. · 2026 · Journal of cardiovascular development and disease
Background The TRI-SCORE was developed to predict mortality after tricuspid valve surgery and has demonstrated prognostic value in patients undergoing transcatheter tricuspid valve interventions (TTVI). Right ventricular-pulmonary arterial…
Ptaszek B, Kurek O, Podsiadło S · 2026 · Lymphatic research and biology
Purpose In times when health and physical activity are gaining in value, the search for effective methods to support fitness and improve quality of life is becoming a priority. One of the therapies that is gaining increasing popularity is…
Eves R, Deppe M, Kandler C et al. · 2026 · Journal of child psychology and psychiatry, and allied disciplines
Background Past studies indicate significant associations between birth anthropometrics, such as relative birthweight or head circumference, and later cognitive performance. Using twin data, we investigated whether these associations are…
Toillon I, Badoud I, Ferrari S et al. · 2026 · Bone
Type 1 diabetes is associated with increased fracture risk, yet the respective contributions of insulin deficiency and replacement to skeletal fragility remain poorly understood. Using insulin-deficient male Akita mice, we characterized…
Kabuga E, Nandi D, Burrell S et al. · 2026 · The Journal of the Acoustical Society of America
Individual animal identification is essential for wildlife conservation and management, aiding in estimating abundance and related parameters. The feasibility of identifying individual field crickets (Plebeiogryllus guttiventris) from…
Garitaonaindia Y, Witteveen S, Dionisio E et al. · 2026 · Journal of the National Cancer Institute
Background Pathological complete response (pCR) and circulating tumor DNA (ctDNA) clearance are increasingly used as intermediate endpoints in neoadjuvant and perioperative immunotherapy (IO) trials. However, whether complete pathological…
Alsharif P, Strauss A, Ng W et al. · 2026 · Family medicine
Background and objectives Point-of-care ultrasound (POCUS) is increasingly used in inpatient settings to evaluate patients. Common applications include cardiac, lung, hemodynamic assessment, and venous access. Teaching and achieving…
Lysdahlgaard S, Jensen J, Pedersen MRV et al. · 2026 · Radiography (London, England : 1995)
Introduction High-quality radiographic positioning is essential for accurate diagnosis in knee imaging. Although artificial intelligence (AI) can assess image quality with high accuracy, its influence on radiographers' clinical…
Watanabe A, Furukawa M, Hiruta R et al. · 2026 · Neurologia medico-chirurgica
Tractography is a technique for visualizing the trajectories of white matter pathways. The most widely used model, the diffusion tensor imaging, assumes a single fiber orientation within each voxel. In contrast, the constrained spherical…
Guo ZM, Cui F, Zhang Y et al. · 2026 · BMC anesthesiology
Background Complex spinal surgery is associated with significant trauma and pain. Herein we tested the hypothesis that increasing the dose of esketamine, as a supplement to patient-controlled analgesia, might improve pain relief after…
Rodak O, Alkali IM, Peris-Diaz MD et al. · 2026 · Reproduction in domestic animals = Zuchthygiene
Ovarian tissue vitrification holds great promise as a preservation technique for endangered wild felids; however, the development of an optimal protocol remains desired. One potential factor affecting success is the equilibration…
Gillessen S, Gobat K, Cathomas R et al. · 2026 · European urology oncology
Background and objective The aim of our study is to determine whether the addition of metformin to enzalutamide can improve the outcomes of men with metastatic castration-resistant prostate cancer (mCRPC). Methods From 2016 to 2021,…
Lizama E, Carcamo-Herrera B, López G et al. · 2026 · Psychoneuroendocrinology
Performance in precision sports such as golf depends on the athlete's ability to regulate psychophysiological responses under competitive pressure. Heart rate variability (HRV), cortisol, and DHEA provide complementary indices of autonomic…
Ho K, Adjei-Afriyie O, Carmona-Martinez R et al. · 2026 · Brain communications
Congenital myasthenic syndromes (CMS) are a group of rare disorders characterized by fatigable muscle weakness and caused by impaired neuromuscular junction (NMJ) function. CMS symptoms are highly variable, but it can be detrimental and…
Morales AA, Camarena V, Peart L et al. · 2026 · Scientific reports
Geleophysic dysplasia (GD) is a rare genetic disorder characterized by short stature, joint contractures, and cardiopulmonary complications, with early mortality, and linked to mutations in ADAMTSL2 (GD1), FBN1 (GD2), or LTBP3 (GD3) genes.…
Metcalfe M, Steward O, Gallardo D · 2026 · Preprint
ABSTRACT Spinal cord injury (SCI) disrupts long-distance communication between the brain and spinal circuits, resulting in persistent motor, sensory and autonomic dysfunction 1 . These deficits arise from the limited regenerative capacity…
Halko ML, Halonen J, Laukkanen M et al. · 2026 · Cognition & emotion
Political and economic challenges, amplified by social media algorithms, are increasingly polarising how people receive and evaluate information. This study examines how political views and immediate emotional reactions shape the perceived…
Kongkhuntian P, Aunmeungtong W, Khongkhunthian P · 2026 · Clinical implant dentistry and related research
Objective This study aimed to compare the effect of PTFE tape wrapping and PTFE-coated titanium alloy screws on the removal torque after cyclic loading and on preload values under repetitive tightening. Methods A total of 60 titanium…
Tournu E, Tourdot-Maréchal R, Coelho C · 2026 · International journal of food microbiology
Phytosanitary and copper treatments in viticulture are essential to protect vines against biotic and abiotic stresses. However, residues from these treatments can persist in grape musts and wines, potentially raising risks to consumer…
McClure Z, Fuller-Tyszkiewicz M, Messer M et al. · 2026 · The International journal of eating disorders
Objective Although a range of evidence-based treatments for eating disorders exist, treatment response varies substantially. The ability to match individuals to a treatment which they are most likely to benefit from may help improve…
Khatri D, Poudel S, Pun Magar L et al. · 2026 · Frontiers in plant science
Soybean meal quality for monogastric animals is limited by low sulfur-containing amino acids, especially methionine and cysteine, while oil oxidative stability is restricted by the high polyunsaturated fatty acid content. This two-year…