A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19859 results in Negative / Null Result Report · page 380 of 662
McVige J, Masset L, Mechtler L et al. · 2026 · Journal of child neurology
Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy,…
Ferreira HRS, Hadden AC, Champagnon J et al. · 2025 · The Science of the total environment
Despite the vital importance of wetlands globally, these habitats have increasingly received anthropogenic materials, such as plastics, which can impact the wildlife these habitats support. Despite commonly found in the nests of Eurasian…
Ohlsen SM, Pirkle SB, Yang J et al. · 2026 · JSES reviews, reports, and techniques
Background Machine learning, a subset of artificial intelligence, enables large language models (LLMs) like ChatGPT and Gemini to analyze data, learn from context, and generate responses without explicit programming. While machine learning…
Qiu K, Hang Y, Lv P et al. · 2025 · Translational stroke research
To evaluate whether endovascular thrombectomy (EVT) combined with best medical management (BMM) is more effective than BMM alone in treating mild stroke patients (National Institutes of Health Stroke Scale score pri ) group and the primary…
Radin D · 2024 · Preprint
The consciousness-collapse interpretation of quantum mechanics was explored by testing if human observation might act like a weak quantum measurement effect in an optical interferometer. Forty-seven participants selected via a worldwide…
Wu Y, Xu Y, Bi Z et al. · 2025 · Journal of oral rehabilitation
Background Previous studies have linked sleep quality to temporomandibular joint disorders (TMD), suggesting a role for snoring in this association. However, the directionality of this relationship remains a subject of debate. This…
Yepes Gómez D, Moreno-Bedoya S, Lohle-Rueda S et al. · 2026 · Frontiers in nephrology
Background Sepsis-associated acute kidney injury (SA-AKI) is common in critically ill patients and carries high short-term mortality despite timely antimicrobials and organ support. Adsorptive hemofilters such as the oXiris ® membrane have…
Horovitz O · 2024 · Preprint
Background: /Objectives: The growing interest in nutritional psychology has sparked exploration into how eating habits impact emotional, cognitive, and physical health. The Theory of Food (ToF) posits that childhood eating patterns shape…
Kiplagat E, Ramezani M, Malla S et al. · 2024 · Preprint
This study investigated the survival and growth of Salmonella in onion extracts and bulbs. Extracts of an array of onion varieties and germplasms were used to evaluate their ability to retard or inhibit Salmonella growth and the…
Baumeister A, Schuurmans L, Schultz J et al. · 2025 · Behaviour research and therapy
Background and aim The efficacy of internet-based interventions (IBI) for various psychiatric disorders is widely established, but little is known about the mechanisms or possible influencing factors. One of the most prominent problems in…
Zhan S, Zhang D, Ou Y · 2026 · Frontiers in psychology
Trauma-related distress in adult women often extends beyond posttraumatic stress disorder (PTSD) to include depressive symptoms and dissociation, yet the roles of mindfulness and self-compassion across these symptom domains remain…
Kurimoto M, Nawashiro T, Nagakura M et al. · 2025 · The Journal of craniofacial surgery
Craniosynostosis limits normal cranial growth, significantly affecting the growth and development of children. This increase in intracranial pressure results in significant cosmetic and functional losses. This study investigated the…
Mao J, Gan Y, Tan X et al. · 2025 · International journal of women's health
Objective High basophil count levels are associated with an increased risk of gestational diabetes mellitus (GDM). We used two-sample Mendelian randomisation (MR) to explore a potential causal relationship. It also aims to offer genetic…
Killer HE, Pircher A, Stekhoven DJ · 2026 · Ophthalmology and therapy
Introduction The Collaborative Normal-Tension Glaucoma Study (CNTGS) is frequently cited as evidence that a 30% reduction in intraocular pressure (IOP) slows progression in normal-tension glaucoma (NTG). This study re-examines the…
Schulz KM, Chavez MC, Forrester-Fronstin Z · 2024 · Preprint
Early pubertal onset during adolescence is consistently linked with increased risk of anxiety and depression in girls. Although estradiol tends to have anxiolytic effects in adulthood, whether sensitivity to estradiol’s anxiolytic actions…
Yang Z, Su Q, Gao J et al. · 2026 · Acta psychologica
Scholars have emphasized the need for longitudinal research to investigate the reciprocal influence of personal belief in a just world (PBJW) and aggressiveness, yet such investigations remain limited. The current study aimed to examine…
Poisson CL, Green IK, Stemmler GM et al. · 2024 · Preprint
To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in the ventral tegmental area (VTA) and…
Matsushima T, Toji N, Wada K et al. · 2024 · Preprint
Embryonic exposure to valproic acid (VPA) and imidacloprid (IMI, a neonicotinoid insecticide) impairs filial imprinting in hatchlings, and the deteriorating effects of VPA are mitigated by post-hatch injection of bumetanide, a blocker of…
Zheng H, Chen W · 2026 · Frontiers in pediatrics
Background and aims Exclusive enteral nutrition is an established induction therapy for pediatric Crohn's disease, but biochemical response varies across patients. We assessed whether baseline gut microbiome features were associated with…
Che Y, Yuan J, Guo J · 2025 · Archives of dermatological research
Observational studies have shown that the risk of developing herpes zoster (HZ) increases with the use of statins. However, there are many confounding factors in observational studies. Therefore, our Mendelian randomization (MR) study…
Tu Y, Xie D, Qian H · 2025 · Medicine
Observational studies have suggested associations between circulating creatine kinase (CK) levels and gastric cancer (GC), yet causality remains uncertain. To evaluate whether genetically predicted CK levels are causally related to GC…
van Lennep JPA, van Middendorp H, Leong OV et al. · 2025 · Scandinavian journal of pain
Objectives To understand how different individuals respond to placebo effects, it is relevant to disentangle the influence of someone's personality and genetic variations. The aim of this exploratory study was to investigate the role of…
Salehi-Reyhani SM, Saadat M · 2024 · Molecular biology reports
Background It is well known that telomerase activity is suppressed in normal human tissues and reactivated in tumors, suggesting that the human telomerase reverse transcriptase (hTERT, MIM: 187270) gene may be involved in carcinogenesis. A…
Naito R, Hiwa R, Inaba R et al. · 2025 · Modern rheumatology case reports
Vesiculobullous dermatomyositis (VD) is a rare manifestation of dermatomyositis (DM) and has been suggested to be associated with malignancy. Although the myositis-specific autoantibodies are associated with distinct clinical presentations…
O'Connor LE, Thoerig RC, Leta CN et al. · 2026 · Advances in nutrition (Bethesda, Md.)
Infants may be exposed to contaminants from environmental and food sources, including human milk (HM) or infant formula (IF). The objective of this series of systematic reviews (PROSPERO: CRD42024530332, CRD42024530336, CRD42024530339, and…
Wade TD, Jabs M, Keegan E et al. · 2024 · The International journal of eating disorders
Objective We examine the small amount of research to date that describes and/or evaluates waitlist interventions as a precursor to treatment for an eating disorder (ED) with the intent to provide recommendations for future research that…
Contente J, Ferreira C, Silva M et al. · 2025 · Journal of bone and joint infection
Introduction : Debridement, antibiotics, and implant retention (DAIR) is recommended for early acute postoperative and late acute periprosthetic joint infections (PJIs). The KLIC and CRIME-80 scores have been proposed to predict DAIR…
Li MS, Wu XQ, Zhou YJ et al. · 2024 · Ying yong sheng tai xue bao = The journal of applied ecology
Species range size is closely related to its ability to migrate and adapt to environmental change. Rapoport's rule predicts that species range size would become larger with increasing latitude or elevation. Empirical evidence for…
Rodriguez-Merchan EC · 2025 · The archives of bone and joint surgery
Periarticular multimodal drug injection (PMDI) is better than FNB (femoral nerve block) in pain relief after total knee arthroplasty (TKA). PMDI of bupivacaine [20 mL 0.5% bupivacaine hydrochloride - HCl (100 mg) following implantation…
Weger HG, Polasek AK, Wright DM et al. · 2024 · The Journal of eukaryotic microbiology
Twenty species/isolates of cyanobacteria and green algae were isolated from cyanobacterial bloom samples in lakes associated with the upper Qu'Appelle River drainage system in southern Saskatchewan, Canada. Three amoebae species…