Negative / Null Result ReportOpen accessMedicine
Sadeghi M, Shahrooz S, Aghamohammadi M et al. · 2025 · BMC research notes
Objective Asthma is a common multifactorial inflammatory disease affecting both children and adults. Various cells and cytokines contribute to this inflammatory process. Smooth muscle contraction, vascular congestion, and airway edema lead…
View details →DOI: 10.1186/s13104-025-07455-1 Negative / Null Result ReportOpen accessMedicine
Pan X, Sarker S, Yu JJ et al. · 2026 · Insects
High rates of pest infestations are frequently reported in low-income homes in the U.S. However, even with access to effective insecticides, most residents are unaware of how to properly control indoor pests. We designed and evaluated the…
View details →DOI: 10.3390/insects17050483 Negative / Null Result ReportMedicine
Kass C, Katz-Greenberg G, Bodner J et al. · 2025 · Transplant immunology
Purpose Belatacept has been associated with less de novo specific antibody (dnDSA) development, but few publications have compared the incidence of dnDSA development between tacrolimus and belatacept-based immunosuppression regimens. The…
View details →DOI: 10.1016/j.trim.2025.102297 Negative / Null Result Report
Ferreira RD, Faleiros Ferreira CH, Gonçalves-Ferri WA · 2025 · Preprint
Background Inhaled nitric oxide (iNO) is a standard treatment for neonatal pulmonary hypertension in high-resource settings. Yet, its efficacy and cost-effectiveness in low- and middle-income countries (LMICs) remain underexplored. This…
View details →DOI: 10.1101/2025.08.19.25333602 Negative / Null Result ReportOpen accessMedicine
Zhang Y, Pan J, Hou J et al. · 2025 · Medicine
Rationale Asthenozoospermia (AZS), a leading cause of male infertility, frequently results from genetic defects that disrupt flagellar assembly. Mutations in the DNAH11 gene can cause abnormal dynein arm structures, leading to AZS and…
View details →DOI: 10.1097/md.0000000000046556 Negative / Null Result ReportMedicine
Masri A, Tully TN, Como K et al. · 2025 · Journal of avian medicine and surgery
Euthanasia is a common veterinary medical procedure performed on terminally ill backyard chickens ( Gallus gallus domesticus ). To reduce stress for these animals, it is important to develop a euthanasia protocol that provides a rapid and…
View details →DOI: 10.1647/avianms-d-24-00022 Negative / Null Result ReportOpen accessMedicine
Lee JH, Hwang K, Jeong WK · 2026 · Clinics in orthopedic surgery
Background Arthroscopic rotator cuff repair is widely performed; yet tendon healing failure still occurs in some cases and remains a challenge. To address this issue, several studies have investigated intraoperative injection or patch…
View details →DOI: 10.4055/cios25235 Negative / Null Result ReportMedicine
Cuadrado C, Breedlove C, Toro H · 2025 · Avian diseases
Vaccination with a recombinant Newcastle disease virus (NDV) LaSota (LS) strain expressing Arkansas (Ark) -type infectious bronchitis virus (IBV) spike ectodomain (Se) protein and granulocyte-macrophage colony-stimulating factor (GMCSF)…
View details →DOI: 10.1637/aviandiseases-d-25-00035 Negative / Null Result ReportMedicine
Daudi S, Zampelis V, Belfrage O et al. · 2025 · The bone & joint journal
Aims Short, uncemented hip stems might provide a favourable alternative in total hip arthroplasty (THA) by preserving proximal bone mass through reduced strain-adaptive remodelling. We evaluated and compared the migration and…
View details →DOI: 10.1302/0301-620x.107b9.bjj-2024-1720.r1 Negative / Null Result ReportMedicine
Steen L, Javed H, Contorno E et al. · 2025 · Transplantation proceedings
Objective The cornerstone of immunosuppression for transplantation is tacrolimus. One of the most reliable routes for administering tacrolimus in porcine models is intramuscular injection. However, the pharmacokinetics of intramuscular…
View details →DOI: 10.1016/j.transproceed.2025.07.030 Negative / Null Result ReportMedicine
Simon S, Shanmugalingam T, Neu T et al. · 2025 · European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Active efflux transporters can play a substantial role in the drug disposition of their substrates in the human body. Efflux transporters like P-glycoprotein (P-gp), multidrug resistance associated protein 1 (MRP1) and breast cancer…
View details →DOI: 10.1016/j.ejps.2025.107333 Negative / Null Result ReportOpen accessMedicine
DE Souza GC, Araujo Filho HB, DE Oliveira CZ et al. · 2025 · Arquivos de gastroenterologia
Background Chemotherapy-induced diarrhea is a common and distressing side effect experienced by patients undergoing cancer treatment, particularly those with gastrointestinal cancer. It can lead to significant health complications,…
View details →DOI: 10.1590/s0004-2803.24612025-020 Negative / Null Result Report
Mitchell Y, Thomas B, Clifford AE et al. · 2025 · Preprint
There is growing recognition amongst non-Indigenous New Zealanders of the importance of te reo Māori, the Indigenous language of Aotearoa (New Zealand). Several initiatives in Aotearoa aim to revitalise te reo Māori. Recent research…
View details →DOI: 10.31234/osf.io/sjfrb_v2 Negative / Null Result Report
Mitchell Y, Thomas B, Clifford AE et al. · 2025 · Preprint
There is growing recognition amongst non-Indigenous New Zealanders of the importance of te reo Māori, the Indigenous language of Aotearoa (New Zealand). Several initiatives in Aotearoa aim to revitalise te reo Māori. Recent research…
View details →DOI: 10.31234/osf.io/sjfrb_v1 Negative / Null Result ReportMedicine
López-Campos Ó, Chabot B, Attema HR et al. · 2025 · Meat Science.
The effect of localized low voltage electrical stimulation (LVES, 45 V) on meat quality and palatability of the longissimus thoracis et lumborum (LTL) and semitendinosus (ST) was evaluated in this study. There were stimulation method ×…
Negative / Null Result ReportMedicine
Modica V, Glávits R, Clewell A et al. · 2025 · International journal of toxicology
Anaerostipes caccae CLB101 (CLB101) is an obligate, anaerobic bacteria that was isolated from the stool of a healthy infant. Due to its ability to produce butyrate and its potential promotion of microbiome health through multiple…
View details →DOI: 10.1177/10915818251367353 Negative / Null Result ReportMedicine
Miravalles C, Kane R, Rossier AT et al. · 2026 · Journal of affective disorders
Background Current treatments for depressive episodes in bipolar disorder are often limited by partial efficacy or delayed therapeutic response. Intravenous scopolamine, a pan-muscarinic antagonist, has shown rapid antidepressant effects…
View details →DOI: 10.1016/j.jad.2025.120888 Negative / Null Result ReportMedicine
Grote A, Genther-Schroeder O, Wilson BK et al. · 2025 · Applied Animal Science
Our objective was to determine the effect of plane of nutrition through 92 d of age on subsequent finishing performance, feed efficiency, and carcass characteristics in beef × dairy crossbred steers. Beef × dairy crossbred steers (n = 109)…
Negative / Null Result Report
Hossain MS, Islam F, Ferdous S et al. · 2025 · Preprint
Introduction Childhood obesity is a rising public health concern, particularly in low- and middle-income countries (LMICs) like Bangladesh, where the rate of obesity in children has increased. South Asian countries, traditionally burdened…
View details →DOI: 10.1101/2025.06.23.25330164 Negative / Null Result ReportOpen accessMedicine
Shammo J, Owczarzak L, Yun NK et al. · 2025 · The oncologist
Background Olaparib is a polyadenosine 5'-disphosphoribose polymerase inhibitor approved to treat advanced ovarian cancers with germline mutations. The link between olaparib-induced anemia and folate deficiency was described in a…
View details →DOI: 10.1093/oncolo/oyaf321 Negative / Null Result ReportOpen accessMedicine
Miller ZE, Digirolamo SJ, Molnar J et al. · 2026 · Pediatric quality & safety
Introduction Emergency department evaluations for acute child sexual assault include anogenital photodocumentation as a standard of care, which has implications for accurate clinical care and forensic significance. If photodocumentation…
View details →DOI: 10.1097/pq9.0000000000000876 Negative / Null Result ReportMedicine
Nishida C, Shimoda B, Weldon RH et al. · 2025 · Archives of orthopaedic and trauma surgery
Introduction Proper lower extremity alignment is important for success and longevity of total knee arthroplasty (TKA). Conventional instrumentation has demonstrated higher rates of mechanical axis (MA) malalignment compared to robotic or…
View details →DOI: 10.1007/s00402-025-05998-3 Negative / Null Result ReportOpen accessMedicine
Fenerich BA, Fernandes JC, Silva CLA et al. · 2026 · Hematology, transfusion and cell therapy
Introduction Insulin Receptor Substrate 1 (IRS1) is differentially expressed in hematological neoplasms suggesting a role in hematopoiesis and neoplastic transformation. Irs1 knockout mice represent a tool to investigate IRS1 function.…
View details →DOI: 10.1016/j.htct.2026.106465 Negative / Null Result ReportMedicine
Zhang S, Jia B, Huang W et al. · 2025 · ACS nano
The toxicity of negatively charged nanoplastics (NNP) to bacteria is generally subtler than that of positively charged counterparts, owing to limited NNP-cell interaction. This study hypothesized that common environmental cations (Na + ,…
View details →DOI: 10.1021/acsnano.5c04610 Negative / Null Result ReportMedicine
Georgiadou EC, Garcia CJ, Taliadorou AM et al. · 2025 · Current Plant Biology
The application of priming agents is a promising strategy to enhance the nutritional content of fruits and overall fruit quality. The current study aimed to assess the effect of the pre-harvest application of various priming agents…
Negative / Null Result ReportMedicine
Yoshiura K, Murata M, Hamasuna M et al. · 2025 · Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
Background The behavioural and psychological symptoms of dementia (BPSD) increase the burden for the caregiver, often leading to difficulties in maintaining home care and triggering psychiatric hospitalisation. Effective management of BPSD…
View details →DOI: 10.1111/psyg.70085 Negative / Null Result ReportMedicine
Kato S, Miwa K, Takano H et al. · 2025 · Inorganic chemistry
Recently, the aromaticity and antiaromaticity of organometallacycles have received much attention to understand the cyclic electronic delocalization through d orbitals on the metal center. Here, we prepared a Pd(II) platina(II)corrole…
View details →DOI: 10.1021/acs.inorgchem.5c00942 Negative / Null Result ReportMedicine
Leong JWK, Lee BH, Haniball J et al. · 2025 · Journal of clinical orthopaedics and trauma
Background Achieving a neutral mechanical axis alignment (MAA) in Total Knee Arthroplasty (TKA) is associated with increased implant longevity and patient satisfaction, and robot-assisted (robotic) TKA is touted to improve implant…
View details →DOI: 10.1016/j.jcot.2025.103145 Negative / Null Result Report
Isezaki T, Yuyama H, Yasumuro O et al. · 2025 · Preprint
Abstract Background: This study evaluated the impact of the combined use of pazopanib hydrochloride (PAZ) and gastric acid suppressants (AS) on the progression-free survival and safety of Japanese patients with sarcoma. Methods: A…
View details →DOI: 10.21203/rs.3.rs-6368835/v1 Negative / Null Result Report
Prajapati S · 2026 · Preprint
Abstract Binary neutron star mergers are known to produce gravitational waves and panchromatic electromagnetic afterglow emission hours to days after coalescence. However, a fundamental question remains unanswered: do these mergers…
View details →DOI: 10.21203/rs.3.rs-9595477/v1