Negative / Null Result ReportMedicine
Harlev C, Bue M, Petersen EK et al. · 2025 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Background Epithelial ovarian cancer remains a leading cause of mortality among gynecological malignancies, with a high incidence of peritoneal carcinomatosis at diagnosis. Hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a…
View details →DOI: 10.1016/j.ejso.2025.110378 Negative / Null Result Report
Sato H, Sumida A · 2025 · Preprint
Conifers generally exhibit narrow, deep crowns, whereas broadleaf trees typically form spherical crowns. A widely accepted hypothesis attributes this difference to variation in solar angles: conifers, which prevail in high-latitude regions…
View details →DOI: 10.22541/au.174192316.68245617/v1 Negative / Null Result ReportOpen accessMedicine
Pihlaja S, Lipsanen J, Ritola V et al. · 2026 · Frontiers in psychology
Among patients receiving internet-delivered cognitive behavioral therapy (iCBT) for depression in routine clinical practice, 101 patients were randomized to either iCBT as usual or to iCBT with add-on scheduled telephone support (STS).…
View details →DOI: 10.3389/fpsyg.2026.1704049 Negative / Null Result ReportMedicine
Abdel-Kerem A, Wei W, Calzado A et al. · 2025 · American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Purpose This study aimed to evaluate the impact of integrating smart glasses with a pharmacy compliance mobile application on the efficiency of completing medication unit inspections. The goal was to compare traditional inspection methods…
View details →DOI: 10.1093/ajhp/zxaf083 Negative / Null Result ReportMedicine
Clark AR, Adams AT, McKinley TO et al. · 2026 · The Journal of surgical research
Introduction Volumetric muscle loss (VML) resulting from severe extremity injuries in combat remains a significant clinical challenge, particularly in austere environments. Current research emphasizes the development and evaluation of…
View details →DOI: 10.1016/j.jss.2025.11.043 Negative / Null Result ReportMedicine
Li J, Wang X, Li J et al. · 2025 · Journal of medical virology
The recently mutated Omicron variant of SARS-CoV-2 exhibits extremely high infectivity and strong evolution and immune escape capabilities. Given the unique epidemic prevention policies of China, we collected 16 sets of sera from…
View details →DOI: 10.1002/jmv.70681 Negative / Null Result ReportMedicine
van Strien-Knippenberg IS, Timmermans DRM, Weber M et al. · 2025 · Health communication
This study aimed to assess whether, in the context of communicating risk-based breast cancer screening results, visualizations of risk information consisting of an icon array depicting quantified breast cancer risk and simplified drawings…
View details →DOI: 10.1080/10410236.2025.2582779 Negative / Null Result Report
Nakano H, Nakagawa K, Ikuno T et al. · 2024 · Preprint
Objective Post-stroke spasticity prevalence increases with time from stroke onset, and negatively impacts the patient’s quality of life. Vibratory stimulation (VS) to the spastic muscles can reduce spasticity, whereas action observation…
View details →DOI: 10.1101/2024.12.03.24318436 Negative / Null Result ReportMedicine
Kuziboev B, Pícha K, Nazif Çatık A et al. · 2025 · Journal of environmental management
This research is the first to investigate the effect of low-carbon energy risk on the diversification of energy sources. To this end, a sample of 64 countries from 2000 to 2018 is analysed. For empirical estimations, we employ the Method…
View details →DOI: 10.1016/j.jenvman.2025.127544 Negative / Null Result Report
Moura RA, Bisiau A, Freeman D et al. · 2025 · Preprint
Background: Perioperative fluid therapy can influence oxygen delivery and tissue oxygenation, but its effects in horses are poorly understood. Objectives: To compare two intraoperative fluid administration strategies on peripheral tissue…
View details →DOI: 10.22541/au.176131103.35539940/v1 Negative / Null Result Report
Hibner A, Tong MK, Liu L et al. · 2025 · Preprint
Abstract OBJECTIVE: To investigate single versus combination hemodynamic parameters on intraventricular hemorrhage (IVH) or mortality in preterm infants. STUDY DESIGN: Data from 482 infants under 32 weeks gestational age were analyzed,…
View details →DOI: 10.21203/rs.3.rs-7376716/v1 Negative / Null Result Report
Far ZS, Nematollahi MA, Hosseini SV et al. · 2025 · Preprint
Abstract Arthrospira platensis, commonly known as Spirulina , is an industrially cultivated cyanobacterium due to its high content of phycobiliproteins, mainly phycoerythrin, phycocyanin, and allophycocyanin. In this work, a low-cost…
View details →DOI: 10.21203/rs.3.rs-7284160/v1 Negative / Null Result ReportMedicine
Godoi Filho JRM, Abreu TFO, Vieira QR et al. · 2026 · Journal of motor behavior
We investigated the influence of mental fatigue on motor performance and learning. Additionally, we examined whether practicing under mental fatigue induces resilience in future performance under similar fatigue conditions. Ninety-two…
View details →DOI: 10.1080/00222895.2025.2585181 Negative / Null Result ReportMedicine
Girgin Y, Vural GS, Yigit Y et al. · 2026 · Experimental eye research
Aim This study aimed to investigate the regenerative efficacy of topically administered insulin on corneal epithelial and stromal healing in a well-established rabbit model of ocular surface damage induced by chemical injury. Methods A…
View details →DOI: 10.1016/j.exer.2025.110775 Negative / Null Result ReportMedicine
Dao GM, Shaw CS, Betik AC et al. · 2025 · Diabetes
Despite stimulating glucagon secretion, the mechanisms by which protein ingestion lowers glucose excursions remain unclear. We investigated this using the triple stable isotope glucose tracer technique to measure postprandial glucose…
View details →DOI: 10.2337/db25-0395 Negative / Null Result ReportMedicine
Bowers AN, Tonon CC, Yeo S et al. · 2025 · Archives of oral biology
Objectives Charcoal-containing dentifrices are increasingly popular for their whitening claims, but data on antimicrobial effects are limited. This study compared the antibacterial efficacy of charcoal dentifrices versus non-charcoal…
View details →DOI: 10.1016/j.archoralbio.2025.106405 Negative / Null Result Report
Homann LA, Jahed M, Barense M · 2025 · Preprint
Retrieval practice—actively recalling information—is an established memory-strengthening technique. However, understanding how retrieval transforms memory requires examining its effects on memories that evolve across multiple episodic and…
View details →DOI: 10.31234/osf.io/923rj_v1 Negative / Null Result Report
Homann LA, Jahed M, Barense M · 2025 · Preprint
Retrieval practice—actively recalling information—is an established memory-strengthening technique. However, understanding how retrieval transforms memory requires examining its effects on memories that evolve across multiple episodic and…
View details →DOI: 10.31234/osf.io/923rj_v2 Negative / Null Result ReportMedicine
Sajjad M, Ghorbaninejad P, Bitarafan V et al. · 2026 · The Journal of nutrition
Background The amino acids, L-leucine (Leu) and L-isoleucine (Ile), and the bitter substance, quinine, reduce postprandial glucose, stimulate insulin, and/or slow gastric emptying. Whether combining these stimuli can enhance these effects…
View details →DOI: 10.1016/j.tjnut.2025.101259 Negative / Null Result Report
Fathollahzadeh I, Hashemi A, Mehan M et al. · 2025 · Preprint
Abstract The existence of empathy in rodents and, more broadly, in lower mammals has been hotly debated. Each group has designed its apparatus to address this issue. While well-established methods for measuring cooperation are in the…
View details →DOI: 10.21203/rs.3.rs-6742141/v1 Negative / Null Result ReportMedicine
Lima Neta PP, Leal PPMS, Passos VHAA et al. · 2025 · Anais da Academia Brasileira de Ciencias
Leishmaniasis is a group of diseases caused by protozoa of the genus Leishmania . Current treatments exhibit high toxicity, high costs, and parasite resistance. Consequently, the search for new drugs is of utmost importance, and drug…
View details →DOI: 10.1590/0001-3765202520250377 Negative / Null Result ReportMedicine
Chou AK, Chiu CC, Chen YW et al. · 2025 · Fundamental & clinical pharmacology
The aim of this study was to examine the effects of intrathecal lidocaine combined with guanfacine or dexmedetomidine on nociceptive and motor blockade, in comparison to clonidine. Using a rat model of intrathecal injection, we evaluated…
View details →DOI: 10.1111/fcp.70057 Negative / Null Result Report
Furukawa H, Nishikawa Y, Saito A et al. · 2025 · Preprint
Abstract This study aimed to examine the effects of visual and auditory cues on step frequency (SF) and physiological load, measured by heart rate (HR), in runners. The experiment involved two runners—a main runner and a neighboring…
View details →DOI: 10.21203/rs.3.rs-6650523/v1 Negative / Null Result Report
Kim T, Lee H, Ryu S et al. · 2025 · Preprint
Abstract In mammalian cell-based bioprocesses, glycosylation of recombinant therapeutic proteins requires stringent control and monitoring as it may affect therapeutic efficacy and safety. The sialylation of glycosylated moieties plays an…
View details →DOI: 10.21203/rs.3.rs-7324359/v1 Negative / Null Result Report
Pulliainen H, Kataja E, Löyttyniemi E et al. · 2025 · Preprint
Abstract Background We examined whether an interactive four-dimensional (4D) ultrasound intervention decreases prenatal and early postnatal depressive symptoms and improves maternal-fetal attachment. Methods This randomized controlled…
View details →DOI: 10.21203/rs.3.rs-6672112/v1 Negative / Null Result ReportMedicine
Clouse DE, Collins EG, Khodakovskaya MV et al. · 2025 · Biomacromolecules
There is growing recognition that both cellulose nanocrystal (CNC) source and production scheme affect their physicochemical properties and dispersion behavior. However, how these differences affect CNC surface chemistry modification has…
View details →DOI: 10.1021/acs.biomac.4c01710 Negative / Null Result Report
Dikici B, Malinowski R, Kordaß J et al. · 2025 · Preprint
During non-rapid eye movement (NREM) sleep, cortical slow oscillation (SO; <1 Hz) and thalamic sleep spindle activity (12-15 Hz) interact through precise phase coupling to support memory consolidation. Slow oscillatory transcranial direct…
View details →DOI: 10.1101/2025.07.03.662520 Negative / Null Result Report
Junior PCGD, Vicente ACS, Santos IJd et al. · 2025 · Preprint
Abstract The study evaluated the effects of orange essential oil (OEO) as a feed additive on nutrient intake, digestibility, nitrogen balance, and rumen fermentation in meat sheep. Using ten rumen-cannulated Dorper × Santa Inês wethers in…
View details →DOI: 10.21203/rs.3.rs-6986736/v1 Negative / Null Result ReportMedicine
Badran PM, Stecca CM, de Souza de Castro JT et al. · 2025 · Clinical radiology
Aim Ovarian cancer is the most lethal gynecologic malignancy, with prognosis linked to stage at diagnosis. Ultrasonography is the first-line tool for adnexal mass evaluation, while computed tomography (CT) supports staging and surgical…
View details →DOI: 10.1016/j.crad.2025.107088 Negative / Null Result ReportMedicine
di Fonzo AR, Bertuzzi ML, Amusquibar MV et al. · 2025 · Animal reproduction science
Zinc oxide nanoparticles (ZnO-NPs) have been reported to enhance sperm cryopreservation in several species, but their effect on frozen llama semen remains unexplored. This study aims to evaluate the effect of ZnO-NPs on sperm parameters in…
View details →DOI: 10.1016/j.anireprosci.2025.107994 