e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19859 results in Negative / Null Result Report · page 370 of 662

Negative / Null Result ReportMedicine

The effect of velocity-based strength training on lower limb maximal strength, power, and muscle thickness: a comparative study of sex-specific adaptations.

Guo, Suo, Xue et al. · 2026 · Frontiers in physiology

This study aims to explore the effects of Velocity-Based Strength Training (VBT) on lower-limb strength, power, and muscle thickness in athletes of different sexes. It aims to identify sex-specific differences in training adaptations and…

View details →DOI: 10.3389/fphys.2026.1787790
Negative / Null Result ReportMedicine

Comparison of methods of Weaning from Nasal Continuous Positive Airway Pressure in Preterm Infants: A Randomized Controlled Trial.

Asif, Rais, Anwar et al. · 2026 · Pakistan journal of medical sciences

To compare the efficacy of different nasal continuous positive airway pressure (NCPAP) weaning strategies in preterm infants presenting with respiratory distress syndrome (RDS). This randomized controlled trial was conducted at the…

View details →DOI: 10.12669/pjms.42.5.15003
Negative / Null Result ReportMedicine

Comparative predictive value of AIMS65, Pre-endoscopic Rockall and Glasgow-Blatchford Scoring Systems in Nonvariceal Upper Gastrointestinal Bleeding.

Cui, Cao · 2026 · Pakistan journal of medical sciences

To compare the predictive ability of the AIMS65, pre-endoscopic Rockall score (Pre-RS), and Glasgow-Blatchford score (GBS) for clinical outcomes in patients with non-variceal upper gastrointestinal bleeding (NVUGIB). This retrospective,…

View details →DOI: 10.12669/pjms.42.5.15131
Negative / Null Result ReportMedicine

Impact of chronic kidney disease on clinical outcomes among patients with atrial fibrillation following percutaneous left atrial appendage occlusion: a multicentre cohort study.

Amin, Awashra, Khan et al. · 2026 · European heart journal open

Atrial fibrillation (AF) and chronic kidney disease (CKD) often coexist, and both increase the risk of thromboembolism and bleeding. We aim to investigate the impact of CKD in patients with AF undergoing left atrial appendage occlusion…

View details →DOI: 10.1093/ehjopen/oeag082
Negative / Null Result ReportMedicine

The effect of music therapy on cognition in neurorehabilitation: A pilot crossover randomized controlled trial.

Gee Lim, Feng Ng, Fen Beh · 2026 · Turkish journal of physical medicine and rehabilitation

This study aims to assess the feasibility of this pilot study's design and implementation and to compare the effect of active and passive music therapy interventions and standard care on cognition in neurorehabilitation. Participants aged…

View details →DOI: 10.5606/tftrd.2026.15231
Negative / Null Result ReportMedicine

A polypill strategy for lipid lowering and anti-platelet therapy after acute coronary syndrome: A pilot randomized controlled trial.

Coellar, Keshvani, Jain et al. · 2026 · American journal of preventive cardiology

Medication non-adherence following acute coronary syndrome (ACS) is common, especially among underserved populations. The use of fixed-dose combination pills (polypills) may improve both adherence and prescription practices. This…

View details →DOI: 10.1016/j.ajpc.2026.101499
Negative / Null Result ReportMedicine

Does exposing all parathyroids during total thyroidectomy with central lymph node dissection protect long-term function? A prospective cohort study.

Jin, Xu, Wen et al. · 2026 · BMC surgery

Hypoparathyroidism (HypoPT) is the most common complication after total thyroidectomy (TT) and central lymph node dissection (CLND) for thyroid carcinoma. However, there's still no effective surgical strategy to prevent its incidence. This…

View details →DOI: 10.1186/s12893-026-03923-y
Negative / Null Result ReportMedicine

Effect of Implant Design on Fracture Resistance, Mode, and Crystal Structure of One- and Two-Piece Zirconia Implants With Ceramic or Titanium Abutment Screws: An In Vitro Study.

Gul, Papia, Eqtesadi et al. · 2026 · Clinical oral implants research

To evaluate the fracture resistance, fracture modes, and crystalline phase changes of zirconia one-piece implants (OPI) and bone-level (BLTPI) or tissue-level, two-piece implants (TLTPI), with ceramic (C) or titanium (T) abutment screws…

View details →DOI: 10.1111/clr.70149
Negative / Null Result ReportMedicine

The Relative Bioavailability of Lutein and Zeaxanthin in the Presence of Omega-3 Supplements and Their Effect on Oxidative Stress Levels in Humans: A Pilot Study.

Kalu, McMonnies, Lin et al. · 2026 · Nutrients

Introduction: Lutein+Zeaxanthin (L+Z) are the major constituents of macular pigments of the retina. There is a lack of information on the bioavailability of the two compounds in the presence and absence of omega-3 fatty acids in L+Z…

View details →DOI: 10.3390/nu18121914
Negative / Null Result ReportMedicine

Arthroscopic Repair of Anterior Labroligamentous Periosteal Sleeve Avulsion Lesions Achieves Similar Outcomes and Labral Height Compared With Typical Bankart Lesions With Adequate Capsulolabral Release.

Chang, Lee, Yoon et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

To compare the serial measurements of repaired labral height in the early and late postoperative periods and clinical outcomes between patients with Bankart lesions and those with anterior labroligamentous periosteal sleeve avulsion…

View details →DOI: 10.1002/arj.70357
Negative / Null Result ReportMedicine

Amide proton transfer-weighted magnetic resonance imaging for predicting histopathology and biomarkers in rectal adenocarcinoma.

Liu, Cui, Sun et al. · 2026 · Quantitative imaging in medicine and surgery

Preoperative evaluation of histopathological features and biomarkers is critical for personalized treatment of rectal adenocarcinoma. Amide proton transfer-weighted (APTw) magnetic resonance imaging (MRI) is a promising noninvasive…

View details →DOI: 10.21037/qims-2025-1-2596
Negative / Null Result ReportMedicine

Comparative evaluation of interdental papilla fills around bone level and tissue level implants: A randomised controlled trial.

Mulay, Bhansali, Indurkar et al. · 2026 · Bioinformation

Early achievement of optimal interdental papilla fill around dental implants remains a clinical challenge affecting aesthetic outcomes in single-tooth replacement. Therefore, it is of interest to compare interdental papilla fill around…

View details →DOI: 10.6026/973206300222332
Negative / Null Result ReportMedicine

Primary High-Grade Spinal Sarcomas: A Retrospective Review of 10 Cases.

Fukushi, Emori, Tsuchie et al. · 2026 · Cureus

Aggressive surgical resection with adequate margins is associated with improved local control and survival in selected patients with primary spinal sarcomas. However, anatomical constraints often preclude complete resection, and outcomes…

View details →DOI: 10.7759/cureus.108569
Negative / Null Result ReportMedicine

Oral Health Status and Utilization of Dental Services Among Adults With Disability Compared to Those Without Disabilities in Nevada, United States.

Benson, Gomez, DerAshodian et al. · 2026 · Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry

This study examines disability-related disparities in tooth loss and dental visits, and Medicaid dental service utilization across Nevada counties in 2022. A cross-sectional analysis of the 2022 Behavioral Risk Factor Surveillance System…

View details →DOI: 10.1111/scd.70195
Negative / Null Result ReportMedicine

Meal Replacement Therapy for Metabolic Dysfunction-Associated Steatotic Liver Disease in Adolescents with Severe Obesity.

Rode, Wolf, Bolan et al. · 2026 · Childhood obesity (Print)

This clinical trial evaluated hepatic fat content and weight loss in adolescents with severe obesity and metabolic dysfunction-associated steatotic liver disease (MASLD) following short-term meal replacement therapy (MRT). Adolescents aged…

View details →DOI: 10.1177/21532176261457202
Negative / Null Result ReportMedicine

Effect of Irreversible Compression on the Pulmonary Nodule Detection Rate in Chest Radiographs Using AI Software.

Kohzai, Yamamoto, Matsushita et al. · 2026 · Diagnostics (Basel, Switzerland)

Objectives : Whereas irreversible compression of Digital Imaging and Communications in Medicine (DICOM) files can reduce data size, research on its impact on diagnostic ability when using artificial intelligence (AI) software is limited.…

View details →DOI: 10.3390/diagnostics16111637
Negative / Null Result ReportMedicine

Consensus-Level and Cluster-Adjusted Evaluation of a Large Language Model for Diagnostic Extraction from Musculoskeletal Radiology Reports.

Bosbach, Montazeri, Senge et al. · 2026 · Diagnostics (Basel, Switzerland)

Purpose: Large language models (LLMs) may reduce administrative workload in radiology by automating structured diagnostic extraction from text reports. This study evaluates the accuracy of ChatGPT-4.0 when extracting correct diagnoses from…

View details →DOI: 10.3390/diagnostics16111590
Negative / Null Result ReportMedicine

Impact of Body Mass Index on Clinical Outcomes of LLETZ.

Paternostro, Joura, Postl et al. · 2026 · Journal of clinical medicine

Background/Objectives: Large loop excision of the transformation zone (LLETZ) is used as a standard treatment for cervical dysplasia. Although obesity is associated with reduced cervical screening participation and may complicate…

View details →DOI: 10.3390/jcm15114307
Negative / Null Result ReportMedicine

Efficacy of High Flow Nasal Cannula in Reducing Hypoxemia in Children Undergoing Elective Flexible Fibreoptic Bronchoscopy as Compared to Conventional Low Flow Nasal Cannula: A Randomized Controlled Trial.

Rajvanshi, Kumar, Goyal et al. · 2026 · Pediatric pulmonology

Flexible fibreoptic bronchoscopy (FFB) is widely used in pediatric pulmonology, though hypoxemia remains a primary concern during the procedure. High-flow nasal cannula (HFNC) has shown potential in reducing hypoxemia in adults undergoing…

View details →DOI: 10.1002/ppul.71683
Negative / Null Result ReportMedicine

Prospective observational comparative study of radiotherapy induced toxicities (xerostomia, skin reaction, and mucositis) between three-dimensional conformal radiotherapy and intensity modulated radiotherapy technique to oral cavity cancer of head and neck.

Dhakar, Ghori, Parihar et al. · 2026 · The Gulf journal of oncology

Oral cavity cancers often require radiotherapy (RT), leading to toxicities such as xerostomia, skin reactions, and mucositis. This study aims to compare these toxicities between three-dimensional conformal radiotherapy (3D-CRT) and…

Negative / Null Result ReportMedicine

Comparison of Interferon-Based and Interferon-Free Treatments on the Prognosis of Hepatocellular Carcinoma After Hepatitis C Virus-Sustained Virological Response: A Multicenter Study.

Itoh, Iseda, Yoshizumi et al. · 2026 · Cancer medicine

We examine the impact of interferon (IFN)-based and IFN-free treatment on the prognosis of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) sustained virological response (SVR). Clinical information was collected on 311 cases…

View details →DOI: 10.1002/cam4.71963
Negative / Null Result ReportMedicine

Oral health-related quality of life after early extraction of primary second molars in children with congenitally missing second premolars: a randomized controlled trial with matched controls.

Naoumova, Nawaia, Krekmanova · 2026 · European journal of orthodontics

Extraction of mandibular primary second molars in patients with congenitally missing second premolars may influence oral health-related quality of life (OHRQoL), yet this has not been previously investigated. To assess the impact of…

View details →DOI: 10.1093/ejo/cjag048
Negative / Null Result ReportMedicine

Utility of Postoperative Thyroid Hormone Levels in Predicting the Diagnosis of Adult Growth Hormone Deficiency in Patients Undergoing Surgery for Nonfunctioning Pituitary Neuroendocrine Tumor: A Pilot Study.

Tsujimoto, Yamashiro, Suzuki et al. · 2026 · International journal of endocrinology

Adult growth hormone deficiency (AGHD) is often diagnosed after surgery for nonfunctioning pituitary neuroendocrine tumor (NF-PitNET). While a growth hormone stimulation test (GHST) is required to establish its diagnosis, it is associated…

View details →DOI: 10.1155/ije/8842344
Negative / Null Result ReportMedicine

Task Shifting in Cardiac Ablations Compared With Percutaneous Coronary Interventions: The Japanese Circulation Society Chugoku-Shikoku Regional Survey Subanalysis.

Fukue, Suetomi, Matsuura et al. · 2026 · Circulation reports

As part of work-style reform for physicians, task shifting to non-physician healthcare professionals has been promoted in Japan. We previously reported task shifting results for percutaneous coronary interventions (PCI), but the status in…

View details →DOI: 10.1253/circrep.cr-25-0329
Negative / Null Result ReportMedicine

Robotic Mitral Valve Repair in Patients With Thoracic Deformity.

Tomita, Kakuta, Kainuma et al. · 2026 · Circulation reports

Robotic mitral valve repair (MVr) offers superior visualization and dexterity, potentially overcoming challenges in severe thoracic deformity such as pectus excavatum. This study compared surgical outcomes after MVr in patients with and…

View details →DOI: 10.1253/circrep.cr-26-0003
Negative / Null Result ReportMedicine

The Impact of Kidney Donor Profile Index and Human Leukocyte Antigen Mismatch on Graft Survival in Pediatric Kidney Transplant Recipients.

Ranabothu, Smith, Perkins et al. · 2026 · Pediatric transplantation

Pediatric kidney transplant recipients typically receive low-KDPI deceased donor kidneys but often experience higher HLA mismatches. The relationship between KDPI and HLA mismatch and their combined effect on graft and patient outcomes in…

View details →DOI: 10.1111/petr.70351