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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19854 results in Negative / Null Result Report · page 363 of 662

Negative / Null Result ReportOpen accessMedicine

Assessment of changes in lung aeration and diaphragmatic function using ultrasonography in laparoscopic abdominal surgery: a prospective observational study.

Sethi D, Prajapati S, Garg G · 2026 · Anesthesia and pain medicine

Background A few studies investigating the perioperative use of lung ultrasound (LUS) have shown loss of lung aeration with decline in diaphragmatic function after general anesthesia. We aimed to measure changes in lung aeration and…

View details →DOI: 10.17085/apm.25248
Negative / Null Result ReportMedicine

Precision, least significant change and validity of body composition estimates from bioelectrical impedance analysis, 3D-optical scanning, and dual X-ray absorptiometry.

Oliver CJ, Del Vecchio L, Climstein M et al. · 2026 · Clinical nutrition ESPEN

Background Accurate assessment of body composition beyond BMI is necessary in clinical care. Bioelectrical impedance analysis (BIA) and 3D scanning (3DS) are practical two-compartment (2C) methods estimating % body fat (%BF), fat mass…

View details →DOI: 10.1016/j.clnesp.2026.102959
Negative / Null Result Report

1-Year Assessment of a Children’s Physical Activity Implementation Strategy with College Student Implementers in a Rural Middle School

Kwaiser MM, King JF, Troyer LE et al. · 2026 · Preprint

Abstract Background Many physical activity interventions exist, but few are sustained, with additional barriers in rural populations. The primary objective was to evaluate the feasibility of a refined implementation strategy for a…

View details →DOI: 10.21203/rs.3.rs-8584037/v1
Negative / Null Result ReportMedicine

Real-world outcomes of naïve, early switch and late switch eyes treated with dexamethasone intravitreal implant for retinal vein occlusion.

Diego-Navarro O, Copete S, Moreno-Martínez A et al. · 2026 · European journal of ophthalmology

PurposeTo evaluate functional and anatomical outcomes after intravitreal dexamethasone implant (DEXI) in macular edema secondary to retinal vein occlusion (ME-RVO), comparing treatment-naïve eyes with early-switch (ES) and late-switch (LS)…

View details →DOI: 10.1177/11206721261461913
Negative / Null Result ReportMedicine

Peripheral Blood Eosinophilia as a Marker of Acute Cellular Rejection in Liver Transplant Recipients: A Retrospective Analysis.

Şafak A, Karakaya E, Yıldırım S et al. · 2026 · Transplantation proceedings

Introduction Although liver biopsy in patients with acute cellular rejection (ACR) is the gold standard for diagnosis, its invasive nature highlights the need for reliable noninvasive biomarkers. With evidence suggesting that peripheral…

View details →DOI: 10.1016/j.transproceed.2026.04.034
Negative / Null Result ReportMedicine

Incremental peritoneal dialysis with days off vs standard-dose peritoneal dialysis: a propensity-matched study (PD holiday).

Parapiboon W, Pattanapongpaibool A, Sanprasert S · 2026 · International urology and nephrology

Purpose The benefits of incremental peritoneal dialysis (IPD) with days off remain controversial. This study aimed to compare the survival rate between IPD with days off and standard-dose peritoneal dialysis (PD). Methods Participants who…

View details →DOI: 10.1007/s11255-026-05207-z
Negative / Null Result ReportOpen accessMedicine

Machine learning for patient selection in corticosteroid decision making in knee osteoarthritis: A feasibility model.

Musbahi O, Pouris K, Hadjixenophontos S et al. · 2025 · World journal of methodology

Background Relieving pain is central to the early management of knee osteoarthritis, with a plethora of pharmacological agents licensed for this purpose. Intra-articular corticosteroid injections are a widely used option, albeit with…

View details →DOI: 10.5662/wjm.v15.i4.105493
Negative / Null Result ReportMedicine

Integrated nonparametric diagnostics and decay modeling reveal contrasting microbial contamination patterns in a semi-enclosed coastal system.

Bushaibah O · 2026 · Environmental monitoring and assessment

Understanding long-term microbial dynamics in semi-enclosed coastal systems is essential for evaluating wastewater-related impacts and informing management responses. This study applies an integrated nonparametric diagnostic framework to…

View details →DOI: 10.1007/s10661-026-15444-5
Negative / Null Result ReportMedicine

Comparison of the Effects of Different Routes of Hysterectomy With Salpingectomy Procedures on the Ovarian Reserve, Ovarian Doppler, and Sexual Function Parameters.

Aytekin AM, Ulusoy HE, Efe MA et al. · 2026 · The journal of obstetrics and gynaecology research

Objective To evaluate the impact of bilateral salpingectomy added to hysterectomy performed via different surgical routes on ovarian reserve, ovarian stromal blood flow, and sexual function in premenopausal women. Methods This prospective…

View details →DOI: 10.1111/jog.70351
Negative / Null Result ReportMedicine

The EQ-5D-3L Questionnaire Demonstrates Moderate Ceiling Effects at One and Two Years After Total Hip Arthroplasty: Preoperative Predictors and Clinical Implications.

Lee YJ, Clement ND, Asopa V et al. · 2026 · The Journal of arthroplasty

Background The objectives were to evaluate whether the EQ-5D-3L questionnaire demonstrated a ceiling effect after total hip arthroplasty (THA), identify which patients were more likely to reach the ceiling score, and determine whether this…

View details →DOI: 10.1016/j.arth.2026.06.036
Negative / Null Result ReportMedicine

Behavioral Evidence for a Chemical Disturbance Cue in Bat Rays (Myliobatis californica).

Bowman J, Cornelius JM, Schoen A et al. · 2026 · Journal of experimental zoology. Part A, Ecological and integrative physiology

The release of waterborne chemical cues is a well-documented anti-predator strategy in teleost fish, allowing individuals to detect, and respond to, predation threats. However, little is known about whether an ancient group of fishes,…

View details →DOI: 10.1002/jez.70102
Negative / Null Result Report

Peer Coaching Adaptive Self-Management Interventions for Young Adults with Congenital Heart Disease (CHASM in ACHD) – A Pilot Randomized Controlled Trial

Balachandran A, Elliot JLN, Curtis S et al. · 2026 · Preprint

Abstract Background: Adolescents and young adults (AYAs) with congenital heart disease (CHD) are frequently lost to follow-up during transition to adult congenital heart disease (ACHD) care. Successful transition requires navigating…

View details →DOI: 10.21203/rs.3.rs-9900638/v1
Negative / Null Result Report

Temporal persistence of unidirectional rhythmic coupling is inversely associated with salivary oxytocin change during facilitated drum circles in children

Kikuchi M, Yoshimura Y, Tanaka S et al. · 2026 · Preprint

Abstract Facilitated drum circles may promote social bonding in children, yet endocrine responses vary widely. In a school-based pilot study (n = 11; aged 9–10 years), we examined whether the temporal structure of facilitator–child…

View details →DOI: 10.21203/rs.3.rs-9139008/v1
Negative / Null Result ReportMedicine

Effectiveness of Interruptive Clinical Decision Support Alerts on Intravenous vs. Oral Acetaminophen Prescribing.

Booth SE, Rubins D, O'Donoghue AL et al. · 2026 · Applied clinical informatics

Intravenous (IV) and oral (PO) acetaminophen have equivalent bioavailability and effectiveness, but IV formulations are significantly more expensive. Clinical decision support (CDS) tools can encourage cost-effective prescribing. We…

View details →DOI: 10.1055/a-2902-8381
Negative / Null Result ReportMedicine

Rate of functional recovery after hip arthroscopy for femoroacetabular impingement syndrome: patient-reported outcomes at three, six, and twelve months.

Seijas R, Vázquez M, Barastegui D et al. · 2026 · International orthopaedics

Purpose To characterise recovery trajectories across nine patient-reported outcomes (PROs) during the first twelve months after hip arthroscopy for femoroacetabular impingement syndrome (FAIS), and to determine whether six-month assessment…

View details →DOI: 10.1007/s00264-026-06912-1
Negative / Null Result ReportMedicine

Impact of DXA acquisition mode on bone mineral density and longitudinal monitoring: Evidence from the Manitoba BMD registry.

Aftabi S, Leslie WD · 2026 · Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

Dual-energy X-ray absorptiometry (DXA) is the gold standard for assessing bone mineral density (BMD), but technical factors such as acquisition mode may affect measurement. On GE Healthcare DXA systems, Thin and Thick modes are often…

View details →DOI: 10.1016/j.jocd.2025.101660
Negative / Null Result ReportMedicine

Molecular crosstalk between lncRNA H19, miR-29a, and JAK2/STAT3 signaling in alopecia areata: a preliminary study.

Abd Elghany AA, Kamel Eyada MM, Maher SA et al. · 2026 · Cytokine

Background Alopecia areata (AA) is a common autoimmune disease which causes non-scarring patches of hair loss and has a 2% lifetime risk. Its chronic, recurrent nature makes treatment difficult. Potential roles of the JAK/STAT pathway,…

View details →DOI: 10.1016/j.cyto.2026.157121
Negative / Null Result ReportMedicine

Effect of a Participatory Learning Capacity-Building Program on Knowledge, Perception, and Breastfeeding Skills Among Female Village Health Volunteers in Thailand.

Boonperm P, Buaboon N, Vatanavilai C et al. · 2026 · Journal of human lactation : official journal of International Lactation Consultant Association

Background Breastfeeding is a key strategy for improving maternal and infant health; however, Thailand continues to fall short of national and international breastfeeding targets. Village Health Volunteers (VHVs) play an essential role in…

View details →DOI: 10.1177/08903344261446114
Negative / Null Result ReportMedicine

Comparison of accelerated corneal collagen cross-linking under normal and increased oxygen concentrations: A pilot study.

Sinha R, Sabir M, Tripathi M et al. · 2026 · Indian journal of ophthalmology

Objective To evaluate the role of local oxygen supplementation in accelerated collagen cross-linking (CXL) in human subjects. Method Patients with progressive keratoconus were enrolled and randomized to undergo accelerated CXL in either…

View details →DOI: 10.4103/ijo.ijo_1965_25
Negative / Null Result ReportMedicine

Longitudinal spatial correlation of retinal sensitivity and structural changes in macular telangiectasia type 2.

Kim S, Kim YJ, Yoon YH et al. · 2026 · International journal of retina and vitreous

Purpose This study aimed to investigate the spatial correlation between retinal structure and function in macular telangiectasia type 2 (MacTel) using Compass fundus-tracked microperimetry. Methods Medical records of 54 eyes from 28…

View details →DOI: 10.1186/s40942-026-00873-8
Negative / Null Result ReportMedicine

Impact of Newborn CCHD Screening Using Pulse Oximetry in the United States.

Ting J, Grills N, Sochet AA et al. · 2026 · Pediatric cardiology

Critical congenital heart disease (CCHD) screening using pulse oximetry was mandated by all states between 2011-2018. We sought to evaluate the effect on the age at initial admission to a children's hospital, the hospital length of stay…

View details →DOI: 10.1007/s00246-026-04307-y
Negative / Null Result ReportMedicine

The Role of Adjuvant Corneal Cross-linking in the Management of Infectious Keratitis: An OCT-Based Assessment Study.

Soliman S, Said D, Maqsood S et al. · 2026 · Advances in therapy

Introduction Infectious keratitis can lead to significant ocular morbidity and threaten vision if not treated promptly with antimicrobial therapy. Adjuvant treatment with corneal cross-linking (CXL) can improve visual outcomes in cases of…

View details →DOI: 10.1007/s12325-026-03621-4