Negative / Null Result ReportMedicine
Vazquez M, Wilkinson LL, Pembroke T · 2026 · Physiology & behavior
Metabolic dysfunction-associated steatotic liver disease (MASLD) affects 38 % of adults globally and has been identified as a significant and increasing contributor to global health and economic burdens. Obesity is significantly associated…
View details →DOI: 10.1016/j.physbeh.2025.115186 Negative / Null Result ReportMedicine
Forehand A, Criswell S · 2025 · Biotechnic & histochemistry : official publication of the Biological Stain Commission
Dogs represent the most common domesticated animal outside of the research arena for whom tissue for pathological diagnosis is requested. Currently, there is a paucity of literature describing the cross-reactivity of anti-human antibodies…
View details →DOI: 10.1080/10520295.2025.2566683 Negative / Null Result ReportMedicine
Kim AL, Lee WK, Kwon S et al. · 2026 · Tissue engineering and regenerative medicine
Background Alzheimer's disease (AD) presents significant unmet medical needs with no effective therapeutic options. Current pharmacological treatments provide only symptomatic relief and do not prevent the ongoing neurodegeneration. Cell…
View details →DOI: 10.1007/s13770-025-00782-1 Negative / Null Result Report
Van Goor F, Francioli L, Sosnay PR et al. · 2025 · Preprint
Rationale Cystic fibrosis (CF) is a chronic, life-limiting genetic disease. CFTR modulators such as elexacaftor (ELX)/tezacaftor (TEZ)/ivacaftor (IVA) have significantly improved clinical outcomes and quality of life for many people with…
View details →DOI: 10.1101/2025.10.16.25338186 Negative / Null Result ReportOpen accessMedicine
Furlong CT, Stanton HL, Yin R et al. · 2026 · Journal of hand surgery global online
Purpose Pain from dorsal wrist ganglion cysts may result from irritation of the terminal branch of the posterior interosseous nerve. Excision of this branch is often used to treat wrist pain from various etiologies, including recurrent…
View details →DOI: 10.1016/j.jhsg.2026.101051 Negative / Null Result ReportOpen accessMedicine
Ashayeri H, Balafar M, Ebrahimi A et al. · 2025 · BMC neurology
Background Therapeutic hypothermia (TH) is an intervention conducted to reduce brain damage in neonatal asphyxia and postcardiac arrest patients. Traumatic brain injury (TBI) dysregulates cerebral blood flow and causes ischemic brain…
View details →DOI: 10.1186/s12883-025-04463-3 Negative / Null Result ReportMedicine
Turner D, Kamadasala K, McGarity B · 2025 · Heart, lung & circulation
The management of anticoagulation in patients with non-valvular atrial fibrillation at high risk of bleeding complications can be challenging. One such group is elderly patients with previous intracranial haemorrhage secondary to cerebral…
View details →DOI: 10.1016/j.hlc.2025.06.1027 Negative / Null Result ReportMedicine
Giorgi J, Flores-Bravo Y, Dandamudi M et al. · 2025 · Heart failure reviews
Interatrial shunt devices (IASDs) and implant-free strategies have emerged as novel approaches for heart failure (HF) management by mechanically unloading the left atrium (LA) to reduce left atrial pressure (LAP), a key driver of pulmonary…
View details →DOI: 10.1007/s10741-025-10580-5 Negative / Null Result ReportMedicine
Gusdorf J, Earle WB, Li S et al. · 2026 · The American journal of cardiology
Atherosclerotic renal artery stenosis (RAS) affects nearly 7% of adults over age 65 and is associated with increased cardiovascular and renal morbidity. Although early observational studies suggested benefit from renal artery stenting,…
View details →DOI: 10.1016/j.amjcard.2025.12.011 Negative / Null Result ReportMedicine
Yazdy GM, Workowski KA, Ghanem KG et al. · 2026 · American journal of obstetrics and gynecology
Bacterial vaginosis, the most common cause of vaginal complaints among reproductive-aged women, is highly recurrent and often challenging to treat. Whether bacterial vaginosis is sexually transmissible has long been questioned by patients,…
View details →DOI: 10.1016/j.ajog.2025.11.001 Negative / Null Result ReportMedicine
Xue J, Ye J, Han P et al. · 2025 · The journal of gene medicine
Background Synovial mesenchymal stem cell-derived exosomes (SMSC-Exos) can regulate macrophage polarization and alleviate knee osteoarthritis (KOA). However, the underlying mechanisms remain unclear. This study explored the role of…
View details →DOI: 10.1002/jgm.70064 Negative / Null Result ReportMedicine
Diener HC · 2025 · Brain : a journal of neurology
A number of neuropeptides, including pituitary adenylate cyclase-activating polypeptide (PACAP), play an important role in the pathophysiology of migraine. Infusions of PACAP in patients with migraine can provoke migraine attacks. A…
View details →DOI: 10.1093/brain/awaf131 Negative / Null Result ReportOpen accessMedicine
Park SK, Chung Y, Oh CM et al. · 2026 · Global heart
Background There have been inconsistent findings regarding the effects of high sodium intake on coronary artery disease (CAD). This study therefore aimed to investigate the relationship between sodium intake and the coronary artery calcium…
View details →DOI: 10.5334/gh.1528 Negative / Null Result ReportOpen accessMedicine
Ichimura Y, Niiyama S, Hirata A · 2026 · Case reports in dermatology
Introduction Basal cell carcinoma (BCC) is the most common skin cancer, with a rising incidence globally. We encountered a patient with the nonpigmented adenoid subtype of BCC. The nonpigmented subtype of BCC accounts for only a small…
View details →DOI: 10.1159/000551351 Negative / Null Result Report
Spyropoulou N, Diamantopoulou S, Patrinos S et al. · 2025 · Preprint
OBJECTIVE: The purpose of this study was to examine and compare the clinical be-havior of indirect onlays/overlays made of lithium disilicate and composite resin and to investigate risk factors associated with restorations failures.…
View details →DOI: 10.20944/preprints202506.2433.v1 Negative / Null Result ReportOpen accessMedicine
Hayat F, Chiu S, Stuart A et al. · 2025 · Journal of gastrointestinal oncology
Background Tobacco smoking accounts for 22% of the pancreatic cancer burden in Australia. Smoking may increase therapy-related adverse effects and was associated with shorter survival in the previous analysis of all stages of pancreatic…
View details →DOI: 10.21037/jgo-2025-186 Negative / Null Result ReportOpen accessMedicine
Gu L, Lin J, Yue J et al. · 2025 · Journal of inflammation research
Janus kinase (JAK) inhibitors, developed for autoimmune diseases, have been repurposed as potential therapies for severe COVID-19. Growing evidence indicates that their clinical utility is heterogeneous and cannot be generalized as a class…
View details →DOI: 10.2147/jir.s554898 Negative / Null Result ReportMedicine
Jain H, Zakieh O, Chanbour H et al. · 2025 · Clinical neurology and neurosurgery
Introduction Coronal malalignment (CM) remains an understudied and challenging problem in adult spinal deformity (ASD) surgery, and the impact of the lumbosacral fractional curve (LSF) correction on postoperative outcomes remains poorly…
View details →DOI: 10.1016/j.clineuro.2025.109152 Negative / Null Result ReportMedicine
Gkini E, Mehta RL, Tearne S et al. · 2025 · COPD
Rationale The Predict&Prevent trial was designed to provide a definitive randomised clinical trial of a personalised early warning decision support system, COPDPredict™. Methods Adults with ≥1 AECOPD were randomly assigned in a 1:1 ratio…
View details →DOI: 10.1080/15412555.2025.2544719 Negative / Null Result Report
Askarian-Amiri S, Weissenhorn W, Sadoul R et al. · 2025 · Preprint
Extracellular vesicles (EVs), including exosomes, are widely believed to mediate intercellular communication by delivering molecular cargo to recipient cells. However, the efficiency and mechanisms of such cargo delivery remain unclear. In…
View details →DOI: 10.1101/2025.04.01.646561 Negative / Null Result ReportMedicine
Manolitsis I, Feretzakis G, Tzelves L et al. · 2025 · Studies in health technology and informatics
The ASCAPE project aims to improve the health-related quality of life of prostate cancer patients using artificial intelligence-driven solutions. This study tries to unravel the complex relationships between patient data variables and…
View details →DOI: 10.3233/shti250634 Negative / Null Result ReportMedicine
Heck MM, Lehmann J, Amiel T et al. · 2025 · European urology
The extent of lymph node dissection (LND) at the time of radical cystectomy (RC) for bladder cancer (BC) may affect oncologic outcomes. We present updated long-term data from a prospective, multicenter, phase 3 trial involving patients…
View details →DOI: 10.1016/j.eururo.2025.09.001 Negative / Null Result ReportOpen accessMedicine
Helk O, Wagner L, Sengölge G et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives: Kidney injury is a frequent complication of multiple myeloma (MM) and monoclonal gammopathies. Podocyte stress markers, such as urinary nephrin and podocin, have been studied in other renal diseases but their utility…
View details →DOI: 10.3390/diagnostics16060922 Negative / Null Result ReportMedicine
Zivkovic Habibi L, Zaibat M, Frenkiel J et al. · 2025 · Soins. Gerontologie
Day care centers are medical and social facilities that provide day care for people over 60 with Alzheimer's or related diseases. The main aim of the study presented here was to assess the impact of horticultural therapy sessions on the…
View details →DOI: 10.1016/j.sger.2024.10.008 Negative / Null Result ReportMedicine
Osama G, Elhilali H, Salah M et al. · 2025 · Strabismus
Purpose To compare the efficacy of two methods: first, bilateral symmetric anteriorization of the inferior oblique muscle and second: combined resection and anteriorization of the inferior oblique (IO) muscle for asymmetric dissociated…
View details →DOI: 10.1080/09273972.2024.2402925 Negative / Null Result ReportMedicine
Sadeghinia A, Emadi SN, Jamshidi S et al. · 2025 · Lasers in medical science
Background Despite extensive research, there is still no consensus on the optimal treatment for Striae distensae (SD). Aim To evaluate the efficacy of ablative (short pulse (SP) mode) versus combined ablative and non-ablative (short pulse…
View details →DOI: 10.1007/s10103-025-04488-7 Negative / Null Result ReportOpen accessMedicine
Dubin A · 2025 · Annals of intensive care
Background Fluids are a key component of shock resuscitation. Nevertheless, their microvascular effects are complex. In fluid responsive patients, fluids may increase tissue perfusion because of the increase in cardiac output. Since shock…
View details →DOI: 10.1186/s13613-025-01607-z Negative / Null Result ReportMedicine
Wregg JF, Hofer A, Gruber-Wackernagel A et al. · 2026 · Experimental dermatology
Water-filtered infrared-A (wIRA) has been proposed to enhance tissue perfusion and modulate fibrosis, but clinical evidence in morphea (localised scleroderma) is limited. We conducted a prospective, intra-individual pilot split-study in 10…
View details →DOI: 10.1111/exd.70273 Negative / Null Result Report
Cradeur A, Abshire M, Schichtel M et al. · 2025 · Preprint
Objectives: This prospective study aimed to assess noise levels in otolaryngology operating rooms (OR), explore noise variation across subspecialties, and examine the correlation between noise, verbal communication, and surgery complexity.…
View details →DOI: 10.20944/preprints202512.0871.v1 Negative / Null Result ReportMedicine
Acikgoz NB, Toplu-Hocaoglu A, Yildirim BA et al. · 2026 · Epilepsy research
Purpose The ketogenic diet has long been used in epilepsy treatment, particularly in drug-resistant cases, but its efficacy in idiopathic generalized epilepsy, including absence epilepsy, remains less studied. This study aimed to evaluate…
View details →DOI: 10.1016/j.eplepsyres.2026.107847 