Negative / Null Result Report
Mrkonjić R, Šribar A, Rudež I et al. · 2026 · Preprint
Background: Cardiac troponin I (TnI) is the reference biomarker for detecting myocardial injury. Saliva has recently emerged as a potential non-invasive diagnostic fluid; however, evidence regarding the clinical utility of salivary TnI…
View details →DOI: 10.20944/preprints202606.0114.v1 Negative / Null Result ReportMedicine
Lan P, Lan T · 2026 · Metabolic syndrome and related disorders
Background Hyperlipidemia constitutes a systemic metabolic disorder. The correlation of cardiovascular disease [CVD] with the triglyceride-glucose index [TyG] in individuals with hyperlipidemia remains unclear. The current study examined…
View details →DOI: 10.1177/15578518251413507 Negative / Null Result ReportMedicine
Gahukamble A, Arikrishnan AM, Thuppale VE et al. · 2026 · Journal of pediatric orthopedics
Background Distal femoral extension osteotomy (DFEO) is an established surgical option for correcting knee flexion deformity (KFD) in children with cerebral palsy. However, the extension deformity created at the distal femur may remodel…
View details →DOI: 10.1097/bpo.0000000000003347 Negative / Null Result ReportMedicine
Almukhlifi Y, Alharbi A, Alghamdi L et al. · 2026 · Scientific reports
Emergency Medical Services (EMS) trainees are exposed to multiple occupational hazards during their training; however, the extent to which their awareness translates into safe professional behaviours remains unclear. This study aimed to…
View details →DOI: 10.1038/s41598-026-56329-4 Negative / Null Result Report
Elrefaey R, Abdelsalam AI, Yara M et al. · 2025 · Preprint
Abstract Background Galectin-3 demonstrates multifunctionality with diverse biological roles. Its potential as a biomarker for inflammation and renal fibrosis has gathered attention. The renal doppler is commonly used as a guide for…
View details →DOI: 10.21203/rs.3.rs-7374078/v1 Negative / Null Result ReportMedicine
Sharma A, Nateghi R, Ayad M et al. · 2026 · Placenta
Introduction The placenta forms a critical barrier to infection through pregnancy, labor and, delivery. Acute placental inflammation in the membranes, diagnosed as Maternal Inflammatory Response (MIR), has short-term, and long-term…
View details →DOI: 10.1016/j.placenta.2026.05.028 Negative / Null Result ReportMedicine
Bandola AM, Wang MH, Guo BF et al. · 2026 · Marine pollution bulletin
Phthalate esters (PAEs) and microplastics (MPs) are emerging contaminants in aquatic environments. However, their co-occurrence in wetland sediments remains poorly understood. This study aimed to quantify PAE concentrations and MP…
View details →DOI: 10.1016/j.marpolbul.2026.119988 Negative / Null Result Report
Ibrahim EA, Alper E · 2026 · Preprint
Abstract Purpose: PSMA PET/CT has transformed prostate cancer management, yet its diagnostic utility is not absolute. It fails to detect PSMA-suppressed disease variants, including treatment-induced neuroendocrine prostate cancer (t-NEPC)…
View details →DOI: 10.21203/rs.3.rs-9598282/v1 Negative / Null Result ReportMedicine
Yokoyama S, Shimada M, Nakagawa J et al. · 2026 · European journal of drug metabolism and pharmacokinetics
Background and objective Vadadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, is transported into hepatocytes via OATP1B1, which is encoded by the SLCO1B1 gene. Although interindividual variability in vadadustat…
View details →DOI: 10.1007/s13318-026-01005-1 Negative / Null Result ReportMedicine
Chen Y, Ren Z, Yan J et al. · 2026 · Urology
Objective To elucidate the association of endogenous circulating testosterone and its related substances with the onset and severity of stress urinary incontinence (SUI) in postmenopausal women. Patients and methods A comparative analysis…
View details →DOI: 10.1016/j.urology.2026.04.047 Negative / Null Result ReportMedicine
Sayur V, Uc C, Baki B et al. · 2026 · Hernia : the journal of hernias and abdominal wall surgery
Background and aim With the increasing use of digital platforms in surgical education, YouTube has become a widely accessible resource for trainees. However, the absence of peer review raises concerns regarding the reliability and…
View details →DOI: 10.1007/s10029-026-03721-8 Negative / Null Result ReportOpen accessMedicine
Koca SB, Kırkgöz T, Kara L et al. · 2026 · BMC endocrine disorders
BACKGROUND: Spexin has an inhibitory effect on the hypothalamus (GnRH expression), pituitary (LH and FSH expression) and ovary (estradiol expression). However, Phoenixin potentiate GnRH-stimulated GnRH receptor expression. Our aim is to…
View details →DOI: 10.1186/s12902-026-02268-0 Negative / Null Result Report
Çiğri E, Çatan İnan F, Gülten S et al. · 2026 · Preprint
Objective: In the present study, cardiovascular risk indices (Atherogenic Index of Plasma [AIP], Atherogenic Coefficient [AC], Castelli Risk Index-1 [CRI-1], and Castelli Risk Index-2 [CRI-2]) and bone mineral density (BMD SDS) were…
View details →DOI: 10.20944/preprints202605.2036.v1 Negative / Null Result ReportMedicine
Altun MNŞ, Yıldız İ · 2026 · Journal of pediatric nursing
Purpose This study aimed to determine the levels of e-health literacy and quality of life in adolescents with Congenital Heart Disease (CHD), to examine associated factors, and to explore the relationship between e-health literacy and…
View details →DOI: 10.1016/j.pedn.2026.04.024 Negative / Null Result ReportMedicine
Sun X, Zhou Q, Qian W et al. · 2026 · BMC medical education
Background Teaching postoperative follow-up for renal cell carcinoma (RCC) is challenging during brief urology rotations. We evaluated a structured module based on a simplified risk model (IMDB: venous invasion, tumor size ≥ 7 cm, systemic…
View details →DOI: 10.1186/s12909-026-09711-9 Negative / Null Result ReportOpen accessMedicine
Mitsea A, Christoloukas N, Rontogianni A et al. · 2026 · Journal of imaging
AI methods (machine learning and deep learning methods) presented promising results concerning the accuracy of dental age estimation and sex determination. Therefore, this pilot study aims to evaluate the efficacy of an artificial…
View details →DOI: 10.3390/jimaging12060239 Negative / Null Result Report
Ye Z, Men R, Shen Y et al. · 2026 · Preprint
Abstract Purpose: The VIATORR Controlled Expansion (VCX) stent-graft was developed to allow more precise control of shunt diameter during transjugular intrahepatic portosystemic shunt (TIPS) creation. However, real-world data on its actual…
View details →DOI: 10.21203/rs.3.rs-9743027/v1 Negative / Null Result ReportOpen accessMedicine
Ulas O, Yuceer RO, Hasbek Z et al. · 2025 · Medicina (Kaunas, Lithuania)
Background and Objectives : Neuroendocrine neoplasms are heterogeneous tumours arising from endocrine gland cells and the neuroendocrine system. Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) constitute two-thirds of this tumour…
View details →DOI: 10.3390/medicina61111952 Negative / Null Result ReportMedicine
Silva VBC, Lucina SB, Wolf M et al. · 2026 · American journal of veterinary research
Objective To assess right ventricular (RV) systolic function using conventional echocardiography and advanced techniques, including strain and tissue motion annular displacement (TMAD), in dogs with and without pulmonary hypertension (PH).…
View details →DOI: 10.2460/ajvr.26.03.0107 Negative / Null Result ReportMedicine
Çerçer Z, Biçer Şahin F, Kanarya T · 2026 · Journal of human lactation : official journal of International Lactation Consultant Association
Background and aim It is important to include fathers in the evaluation of the breastfeeding process. This study aimed to assess fathers' breastfeeding attitudes and participation. Methods The cross-sectional study data were collected…
View details →DOI: 10.1177/08903344261434532 Negative / Null Result ReportMedicine
Igarashi A, Rekate A, Fujiwara K et al. · 2026 · Acta ophthalmologica
Purpose To evaluate whether early postoperative corneal thickness is associated with 12-month endothelial cell and visual outcomes after Descemet membrane endothelial keratoplasty (DMEK). Methods This retrospective multicentre study…
View details →DOI: 10.1111/aos.70166 Negative / Null Result ReportMedicine
Pillet P, Tremblay-Mercier J, Picard C et al. · 2026 · Neurobiology of aging
Preclinical studies consistently associate body temperature with tau phosphorylation in the brain. This study examined the relationship between body temperature taken at lumbar puncture (LP) and CSF pTau181 levels in 142 cognitively…
View details →DOI: 10.1016/j.neurobiolaging.2026.06.003 Negative / Null Result Report
CAI J, ZHAO P, LIN R et al. · 2025 · Preprint
Abstract The purpose of this study is to analyze the relationship between RPE-based method and internal training load (%HRavg, Banister's TRIMP, and Edward's TL) among high-level female volleyball players. 31 Chinese youth high-level…
View details →DOI: 10.21203/rs.3.rs-7342917/v1 Negative / Null Result ReportMedicine
Hamama I, Katodia V, Landry NM et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM
Objectives Hypoglycemia is a common metabolic problem in newborns, often asymptomatic but can lead to cognitive impairment and neuromotor delays. This study assesses the practicality and accuracy of whole blood capillary bedside glucose…
View details →DOI: 10.1515/jpem-2025-0736 Negative / Null Result ReportMedicine
Bakaç E, Bayburt KA, Diker N et al. · 2026 · Cranio : the journal of craniomandibular practice
Objective To assess early temporomandibular joint (TMJ) adaptation by evaluating angular and volumetric changes of the mandibular condyle relative to the cranial base in skeletal Class III patients following orthognathic surgery using…
View details →DOI: 10.1080/08869634.2026.2656900 Negative / Null Result Report
Han H, Huh Y, Lee SW et al. · 2026 · Preprint
Abstract Background: Electroencephalography (EEG) has emerged as a promising biomarker for predicting motor recovery in stroke patients undergoing non-invasive brain stimulation (NIBS), including repetitive transcranial magnetic…
View details →DOI: 10.21203/rs.3.rs-9648366/v1 Negative / Null Result ReportOpen accessMedicine
Elyasi B · 2026 · Veterinary medicine and science
Background The main goal of this study was to identify various brightness, motion and Doppler echocardiographic variables in small-breed dogs with myxomatous mitral valve disease. Animals Sixty client-owned small-breed dogs with mitral…
View details →DOI: 10.1002/vms3.70922 Negative / Null Result ReportOpen accessMedicine
Aydemir M, Sarkılar G, Atay T et al. · 2026 · Turk gogus kalp damar cerrahisi dergisi
Background Hypotension during anesthesia induction is a clinically significant event linked to perioperative complications. This study aimed to assess if arterial stiffness and stiffness index, measured by Doppler ultrasonography (USG),…
View details →DOI: 10.4274/tjtcs.2025.28548 Negative / Null Result ReportMedicine
Kook PH · 2026 · Journal of feline medicine and surgery
ObjectivesIt remains unclear whether pancreatic lipase immunoreactivity (PLI) and lipase activity similarly reflect clinical status and disease severity in cats with suspected pancreatitis. This retrospective cohort study aimed to directly…
View details →DOI: 10.1177/1098612x261451449 Negative / Null Result ReportMedicine
Sakai M, Miyati T, Ohno N et al. · 2026 · Magnetic resonance imaging
Purpose To apply dynamical network biomarker (DNB) theory to diffusion MRI and develop the diffusion MRI-derived DNB (dMRI-DNB) index for evaluating neurofluid fluctuation in idiopathic normal pressure hydrocephalus (iNPH). Methods…
View details →DOI: 10.1016/j.mri.2026.110728 