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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19854 results in Negative / Null Result Report · page 348 of 662

Negative / Null Result Report

Optimizing Early Compressive Strength of Ultrafine POFA-Based Green HSC: An Experimental and RSM Approach with Silica Fume and Hybrid Fibers

Alani AH, Ahmed D, Al-obaidi QA et al. · 2026 · Preprint

Recently, studies have focused on producing green, sustainable concrete with improved environmental performance, utilizing recycled waste materials. The early compressive strength of Green High Strength Concrete (GHSC) containing up to 60%…

View details →DOI: 10.12688/f1000research.175237.4
Negative / Null Result ReportOpen accessMedicine

No Evidence of Association Between Human 24-Hour Urinary Dopamine and Weight, BMI or Glucose Homeostasis in a Retrospective Analysis.

Mattelaer N, David S, Steenackers N et al. · 2026 · International journal of endocrinology and metabolism

Background Dopamine is an essential neurotransmitter involved in motivation and reward. In obesity, altered dopaminergic responses to food may drive excess energy intake, implicating dopamine in the pathophysiology of obesity.…

View details →DOI: 10.5812/ijem-166881
Negative / Null Result ReportMedicine

Development and Validation of the Nurses' Performance for Enhancing Patient Participation Scale.

Zhu L, Thungjaroenkul P, Abhicharttibutra K et al. · 2026 · Journal of nursing measurement

Background and Purpose: Patient participation is fundamental to modern health care. No validated instrument exists to assess nurses' performance in enhancing patient participation within Chinese health care. This study developed and…

View details →DOI: 10.1891/jnm-2025-0169
Negative / Null Result ReportMedicine

Relationship between hamstring flexibility (askling H-test) and isokinetic strength ratios in elite soccer players with prior hamstring strain injury: A cross-sectional study.

Takla MKN, Rageh MRM, Aboalata MAM et al. · 2026 · Journal of back and musculoskeletal rehabilitation

BackgroundRecurrent hamstring strain injuries are associated with deficits in eccentric strength and altered muscle-tendon extensibility, which may persist and contribute to reinjury risk.ObjectiveTo examine the relationship between…

View details →DOI: 10.1177/10538127261462651
Negative / Null Result Report

Inter-Limb Asymmetry and Its Limited Role in Physical Performance and Match Demands in Football Players with Spastic Hemiparesis: A Team Study

Peña-González I, Roldán A, Barquero BL et al. · 2026 · Preprint

Background: Inter-limb asymmetry has been widely studied as a potential determinant of physical performance in able-bodied athletes; however, its functional relevance in athletes with neurological impairments such as spastic hemiparesis…

View details →DOI: 10.20944/preprints202606.1603.v1
Negative / Null Result Report

Knowledge of Primary Pediatric Care Providers Regarding Attention Deficit Hyperactivity Disorder (ADHD) in the Southern Region, Saudi Arabia: A Cross-Sectional Study

Alwahbi Z, Asiri A · 2026 · Preprint

Abstract Purpose To assess the level of knowledge regarding ADHD among primary pediatric care providers and to identify factors associated with higher or lower knowledge levels in the southern region of Saudi Arabia in 2026. Methods This…

View details →DOI: 10.21203/rs.3.rs-9912726/v1
Negative / Null Result ReportMedicine

Severe visual loss and ocular complications after intra-arterial chemotherapy for retinoblastoma.

Solera-de-Andrés C, Spang-Valencia P, Peralta-Calvo J · 2026 · The British journal of ophthalmology

Background Retinoblastoma (RB) treatment aims to ensure survival, globe preservation and visual function. Intra-arterial chemotherapy (IAC) has improved globe salvage, but there remains limited information on visual outcomes following this…

View details →DOI: 10.1136/bjo-2025-328113
Negative / Null Result ReportMedicine

Density is a precursor in the perception of visual numerosity: Evidence from adaptation.

Durgin FH, Love A, Taylor G et al. · 2026 · Journal of experimental psychology. Human perception and performance

To dissociate density-based and number-based explanations of the aftereffects affecting visually perceived numerosity, a preregistered psychophysical experiment was conducted with 60 participants. The experiment was designed to address a…

View details →DOI: 10.1037/xhp0001434
Negative / Null Result ReportOpen accessMedicine

Spatioseasonal Variability and Correlations of Particle-Bound Organophosphate Esters in Providence, Rhode Island.

Gathof A, Jahaj L, Patalano S et al. · 2025 · ACS omega

The concentrations of organophosphate esters (OPEs) in atmospheric particulate matter (PM) collected every 6 days at two sites across Providence, Rhode Island (Providence College, PC, and the Port of Providence, Port) are reported for the…

View details →DOI: 10.1021/acsomega.5c07462
Negative / Null Result ReportOpen accessMedicine

Correlation Between Baseline Serum Testosterone Levels and Cognitive Gain Following Combined Oral Contraceptive Treatment in Patients With Polycystic Ovary Syndrome.

Kumari S, Marwah S, Manna S et al. · 2026 · Cureus

Background Combined oral contraceptives (COCs) are the cornerstone therapy for polycystic ovary syndrome (PCOS). While COCs have been shown to improve cognitive performance, the relationship between these gains and hormonal profiles,…

View details →DOI: 10.7759/cureus.108574
Negative / Null Result Report

Long-term and monthly changes in population characteristics and spatial distribution of the swimming crab Portunus trituberculatus in the Bohai Sea

Wu Q, Han Q, Shan X et al. · 2026 · Preprint

Abstract With the global decline of fish stocks, crustaceans have gained increasing ecological and economic significance. Portunus trituberculatus is a key crab species in the Asia-Pacific, with its highest density in China's Bohai Sea.…

View details →DOI: 10.21203/rs.3.rs-9095878/v1
Negative / Null Result ReportMedicine

A Comparative Analysis of Differences in Salivary hBD-2 Levels and Their Correlation with Dental Caries and Unstimulated Saliva pH in Children with Primary and Permanent Dentition.

Stojković B, Igić M, Jevtović Stoimenov T et al. · 2026 · Diagnostics (Basel, Switzerland)

Background/Objectives : This exploratory study aimed to investigate potential differences and associations between salivary hBD-2 levels and dental caries, as well as between unstimulated salivary pH and salivary hBD-2 levels, in children…

View details →DOI: 10.3390/diagnostics16040591
Negative / Null Result Report

The Correlation Between Cognitive Function and Motoric Function With Quality of Life in Chidren Suspected of Down Syndrome

Mauludin MR, Permana I, Pratamawati TM et al. · 2026 · Preprint

Abstract Down syndrome is a genetic disorder caused by the presence of an extra copy of chromosome 21, commonly referred to as trisomy 21. In 2020, its prevalence was estimated at approximately 1 in 10.000 live births. The presence of an…

View details →DOI: 10.21203/rs.3.rs-9119273/v1
Negative / Null Result ReportOpen accessMedicine

FeNO as a Non-Invasive Biomarker of Type 2 Inflammation in Chronic Rhinosinusitis with Nasal Polyps: Correlation with Serum IgE and Eosinophils.

Fereydouni S, Jabbari-Azad F, Bakhshaee M et al. · 2026 · Iranian journal of otorhinolaryngology

Introduction Chronic rhinosinusitis with nasal polyps is a heterogeneous inflammatory disorder often driven by type 2 inflammation. Identification of non-invasive biomarkers, such as fractional exhaled nitric oxide (FeNO), may support the…

View details →DOI: 10.22038/ijorl.2025.88968.3979
Negative / Null Result ReportMedicine

Associations Between Dynamic Quantitative Sensory Testing and Physical Therapy Outcomes in Chronic Low Back Pain: An Exploratory, Prospective Longitudinal Cohort Study.

Petrey K, Golden A, Durbin J et al. · 2026 · European journal of pain (London, England)

Background The primary objective of this study was to determine whether baseline conditioned pain modulation (CPM) is associated with pain and disability outcomes following a 6-week course of physical therapy intervention. Secondary…

View details →DOI: 10.1002/ejp.70312
Negative / Null Result ReportMedicine

Short-term neurocognitive changes among people living with HIV assessed using the International HIV Dementia Scale.

Patel A, Meena DS, Santhosh K et al. · 2026 · Journal of neuroimmunology

Background Neurocognitive dysfunction remains an important complication among people living with HIV (PLWH). Early identification of neurocognitive dysfunction by using the International HIV Dementia Scale (IHDS) may help in the prevention…

View details →DOI: 10.1016/j.jneuroim.2026.579001
Negative / Null Result ReportMedicine

Different effect of aldosterone on corrected HCO<sub>3</sub><sup>-</sup> across primary aldosteronism subtypes.

Yasuda H, Yokota K, Katabami T et al. · 2026 · Hypertension research : official journal of the Japanese Society of Hypertension

Primary aldosteronism (PA) causes biochemical abnormalities such as hypokalemia and metabolic alkalosis. This study aimed to compare the effects of aldosterone on serum potassium and corrected bicarbonate (cHCO 3 - , defined as Na - Cl -…

View details →DOI: 10.1038/s41440-026-02609-5
Negative / Null Result ReportMedicine

Axial length, anterior chamber parameters, and white-to-white corneal diameter: Their inter-correlations with intraocular pressure among young Saudis.

Alotaibi W, Alrasheed S · 2026 · JPMA. The Journal of the Pakistan Medical Association

Objective To evaluate axial length, anterior chamber angle, anterior chamber depth, refractive errors and white-to-white corneal diameter, and to assess their inter-correlations with intraocular pressure among young individuals. Methods…

View details →DOI: 10.47391/jpma.20964
Negative / Null Result ReportOpen accessMedicine

Sex differences modulate olfactory bulb volume-function relationships but not olfactory training-induced plasticity.

Hsieh YT, Liao YC, Dulnuan HGP et al. · 2026 · Brain structure & function

Men typically display larger olfactory bulb (OB) volumes, while women demonstrate superior olfactory performance. Olfactory training (OT) has been shown to induce structural changes in OB, but whether sex influences OT-related plasticity…

View details →DOI: 10.1007/s00429-026-03126-4
Negative / Null Result ReportMedicine

Correlation between blood biomarkers and patient-reported outcomes (PROs) of depression and mental health scores in individuals with multiple sclerosis (iwMS).

Baharnoori M, Glanz B, Polgar-Turcsanyi M et al. · 2026 · Journal of the neurological sciences

Background Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are promising biomarkers for Multiple Sclerosis (MS) disease activity. There is less known about their association with the symptomatic…

View details →DOI: 10.1016/j.jns.2026.125786
Negative / Null Result ReportOpen accessMedicine

Positive correlation between IL-6 levels and lumbar bone mineral density in menopausal women diagnosed with osteoporosis in comparison to menopausal women without osteoporosis.

Alhosseini R, Aghaie M, Ghorbani S et al. · 2026 · BMC research notes

BACKGROUND: Osteoporosis is a common bone disorder characterized by decreased bone density. Interleukin-6 (IL-6), plays a crucial role in bone homeostasis. This study aimed to evaluate the relationship between serum levels of IL-6 and…

View details →DOI: 10.1186/s13104-026-07811-9
Negative / Null Result ReportMedicine

Multiple sclerosis and related disorders multiple sclerosis across Isfahan Province, Iran: Urban-rural disparities and no association with air quality measures.

Etemadifar M, Bagheri S, Dehghani A et al. · 2026 · Multiple sclerosis and related disorders

Background Multiple sclerosis (MS) prevalence varies worldwide and appears to be rising in Iran. Environmental factors like air pollution have been hypothesized to contribute to MS risk. This study aimed to map MS prevalence across Isfahan…

View details →DOI: 10.1016/j.msard.2026.107025