A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19854 results in Negative / Null Result Report · page 347 of 662
Pacheco CFO, Costa RF, Silva AEB et al. · 2026 · Forest Ecology and Management.
Mangroves face increasing threats from human degradation and extreme weather events, yet limited information exists on whether they can naturally recover after those disturbances. In this study, we attempted to fill this gap by assessing…
Antonarakis ES, Antonarakis ES, Cao Q et al. · 2026 · Clinical cancer research : an official journal of the American Association for Cancer Research
Purpose This multicenter, single-arm, phase II trial evaluated the safety and efficacy of cabazitaxel and carboplatin followed by abiraterone, plus androgen deprivation therapy (ADT), in patients with high-volume metastatic…
Wanner P, Ostermair F, Cristini J et al. · 2026 · Experimental brain research
A single bout of cardiovascular exercise (CVE) can promote neuroplasticity in an intensity-dependent manner. Consequently, performing CVE immediately after encoding may enhance motor memory consolidation, with stronger effects reported for…
Agarwal N, Rochat P · 2025 · Preprint
Across two experiments, children (N = 259, ages 4–10) evaluated protagonists who either protested unfair, arbitrary rules ("good trouble") or upheld the status quo. Study 1 demonstrates that from age 5, children prefer affiliating with…
Almeida OP, Page A, Etherton-Beer C · 2026 · International psychogeriatrics
Behavioural and psychological disturbances are common among individuals with dementia. It is unclear if the use of antidementia medicines reduces their presence. This study aimed to clarify if the introduction of antidementia medicines…
Getachew ED, Wronski ML, Van De Water AL et al. · 2026 · The International journal of eating disorders
Objective Avoidant/restrictive food intake disorder (ARFID) is an eating disorder characterized by persistent avoidant/restrictive eating unrelated to body image. Sex differences in clinical phenotypes and neurobiology of ARFID are…
Pohjola A, Asikainen A, Kaprio J et al. · 2026 · Neurology
Background and objectives The growing use and improved accessibility of noninvasive imaging modalities have increased the detection of incidental intracranial findings, such as unruptured brain arteriovenous malformations (AVMs). At the…
Crawford M, Leonardi C, Martin MP et al. · 2026 · Journal of surgical orthopaedic advances
This study sought to characterize patient interest in utilizing telemedicine for orthopaedic surgery clinic visits in a primarily Medicaid population. The authors hypothesized that interest in telemedicine would be associated with higher…
De Laet H, Nijhof A, Wiersema JR · 2025 · Preprint
While prevailing theories suggest social interaction difficulties are inherent to autism, the theory of the double empathy problem (DEP) proposes these difficulties arise from a mismatch between different neurotypes. The theory predicts…
Tröger A, Schneider J, Tsapekos D et al. · 2026 · Preprint
Intro: Many people with bipolar disorder (BD) experience persistent cognitive deficits. Sleep spindles have been linked to cognitive ability in healthy populations and psychotic disorders. While there is preliminary evidence for altered…
Raidl P, Vogl A, Dreisoerner A et al. · 2025 · Preprint
Introduction: Prior evidence suggests that individuals with higher fitness exhibit attenuated endocrine and autonomic responses to acute stress. However, it remains unclear whether this stress-buffering effect depends on the type of…
Lorrimar V, van Mulukom V · 2025 · Preprint
In an era of polycrisis, the philosophy of longtermism posits that positively influencing the long-term future is a key moral priority. This study investigates psychological factors predicting moral concern for future generations, focusing…
Le Blanc-Brillon J, Fortin JS, Lafrance L et al. · 2025 · Frontiers in psychology
Introduction Social networking sites (SNSs) have become an integral part of daily life, raising concerns about their potential impact on mental health. One key mechanism through which SNSs may affect wellbeing is social comparison. The…
Smulligan KL, Lempke LB, Mannix RC et al. · 2026 · The Journal of pediatrics
Objective To investigate whether slower reaction time (RT) was associated with higher concussion odds among middle school female soccer players. Study design We performed a retrospective cohort study, analyzing pre-participation…
De Laet H, Nijhof A, Wiersema JR · 2025 · Preprint
Purpose: Autism is associated with social interaction and communication difficulties. The theory of the double empathy problem challenges the idea that these difficulties are inherent to autism, arguing that they rather stem from a…
Kemp LT, Smeets T, Jansen A et al. · 2026 · Journal of behavior therapy and experimental psychiatry
While studying appetitive and aversive conditioning is common in psychopathology research, studies that measure both types of learning simultaneously are rare. To gain insight into the role of appetitive and aversive learning in the…
Del Grosso SJ, Nichols KL, Delgado JA et al. · 2025 · Nutrient cycling in agroecosystems.
Grassland soils managed with livestock grazing can act as sources and sinks for methane (CH₄) and nitrous oxide (N₂O), but, in aggregate, are typically a source of N₂O and a sink for CH₄. Previously, we observed higher N₂O losses from…
Arriero-Cabañero A, Díaz-Rubio N, Talabán-Rocha C et al. · 2025 · Molecular neurobiology
Pyruvate kinases are key enzymes of glycolytic metabolism of neurons and glia. One of them, pyruvate kinase M2 (PKM2) can also act as a transcriptional regulator and in this function has been implicated in several neurodegenerative…
Moreau AL, Rappaport BI, Saturday ML et al. · 2026 · Journal of psychiatric research
Intolerance of uncertainty (IU) is an individual difference dimension reflecting negative cognitive, emotional, and behavioral responses to uncertainty. IU is an important etiological and maintaining mechanism of internalizing…
Elster A, Ron L · 2026 · Journal of personality
Introduction Behavior is not solely determined by individual dispositions or situational demands, but by the dynamic interplay between them. The current research investigates the contextual sensitivity of behavioral determinants by…
Raidl P, Vogl A, Dreisörner A et al. · 2026 · Psychophysiology
Prior evidence suggests that individuals with higher fitness exhibit attenuated endocrine and autonomic responses to acute psychological and physical stressors. However, it remains unclear whether this stress-buffering effect depends on…
Varden Gjerde K, Bartz-Johannessen C, Løberg EM et al. · 2026 · Schizophrenia research
Background Schizophrenia patho-etiology may involve endothelial inflammation and blood-brain barrier (BBB) dysregulation with cellular adhesion molecules (CAMs) as important mediators. CAMs are essential for cellular integrity but can show…
Chhabra BR, Madan AK, Tichansky DS · 2025 · Cureus
Introduction Relationships with industry may create a potential conflict of interest (COI). Disclosure of COI is essential for integrity of educational programming. In 2013, Center for Medicare and Medicaid Services (CMS) developed the…
Lin X, Lee JB, Phua HP et al. · 2025 · Preprint
Introduction Migrants are drawn to high-income countries (HICs) for employment, often in sectors deemed difficult, risky, and low paying. However, they experience more injuries and deaths and face barriers to healthcare. The World Health…
Hashimoto C, Yoshino A, Hida S et al. · 2025 · Preprint
Abstract Background With the increasing diversity of nationalities in Japan, the number of foreign patients with limited Japanese language proficiency is growing. While various multilingual support resources have been developed in recent…
Chung YH, Williams L, Brady TF et al. · 2025 · Preprint
Across many studies, verbal labels have been shown to significantly affect perceptual and cognitive processes. Here we ask whether verbal labels can also improve visual working memory performance by making objects more recognizable. In a…
Weerakoon SM, Henson-Garcia M, Rose R et al. · 2025 · Community health equity research & policy
BackgroundBlack and Latinx youth are disproportionately exposed to neighborhood violence and related mental health challenges. Racial-ethnic identity shapes how adolescents perceive, interpret, and cope with stressful environmental…
van Witteloostuijn M, Blom E · 2025 · Journal of communication disorders
Multilingual children naturally encounter language mixing in their environment. Since children's language development depends on their language input, and processing language mixing in the input may be cognitively demanding, the amount of…
Pizzolla E, Fiorio M, Marotta A et al. · 2026 · Quarterly journal of experimental psychology (2006)
Fatigue has a profound impact on various sensory and perceptual processes; yet, its effects differ depending on whether it arises from physical or mental exertion. While physical fatigue is known to alter body weight perception, it remains…
Traylor DA, Nunes EA, Lees MJ et al. · 2026 · Health science reports
Background and aim Testosterone is an important hormone in male physiology, playing a key role in reproductive function, muscle growth, bone mineral density, and metabolic regulation. Cold exposure is celebrated in fitness and wellness…