A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19854 results in Negative / Null Result Report · page 346 of 662
Mohan Kumar R, Gomaa AR, Scarffe D et al. · 2026 · Foot (Edinburgh, Scotland)
Introduction Achilles Tendon Ruptures (ATR) in sport has only previously been investigated in an athletic population. Our aim in this study was to understand the psychology and function of ATR and their return to sport. Methods A historic…
Morais RF, Duro D, Pires R et al. · 2026 · Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
Background Emotion perception is the capacity that enables humans to correctly identify the cues that guide interpersonal interactions, forming the basis for social behavior. The parahippocampal cortex may contribute to emotion perception…
Ford LB, Irvine M, Lee H et al. · 2026 · HLA
Mismatched allogeneic haematopoietic stem cell transplants (HSCT) are complicated by the presence of pre-existing HLA-specific antibodies targeting the mismatched HLA antigens (DSAs). Data indicates that the presence of DSAs…
Nithya M, Titiyal R, Ajayababu A et al. · 2026 · Journal of clinical medicine
Background: Obstructive sleep apnea (OSA) is common in individuals with obesity, largely due to increased soft tissue causing upper airway narrowing. However, mechanisms of OSA improvement following weight loss are incompletely understood,…
Soumboundou SM, Ndiaye ML, Ndiaye R et al. · 2026 · Cureus
Introduction The advent of 3D imaging has created a significant opportunity to enhance the accuracy of age estimation. By utilizing 3D segmentation, it is now possible to evaluate the three-dimensional pulp volume as an indicator of age.…
Kong W, Mosciatti A, Boulanger J et al. · 2026 · Preprint
Paul Green hypothesized that growth anisotropy of plant cylindrical organs could be controlled by cell-wall elastic strain. The present study aimed to challenge this hypothesis through a robust experimental and analytical framework. By…
Lee BJ, Kong IJ, Yoon JA · 2026 · Lymphatic research and biology
Purpose To examine the association between clinical severity and lymphatic function of breast cancer-related lymphedema. Methods and results A total of 151 patients with lymphedema after breast cancer-related mastectomy were enrolled. The…
Fedeli L, Magistrelli A, Vaiano A et al. · 2026 · Journal of radiological protection : official journal of the Society for Radiological Protection
The reduction of the annual equivalent dose limit to the lens of the eye from 150 to 20 mSv has increased the need for reliable assessment of occupational eye lens exposure, particularly in interventional radiology. Lens absorbed dose is…
Brandtzäg AA, Eiberg JP, Taudorf M et al. · 2026 · EJVES vascular forum
Introduction To evaluate intra-arterial pressure measurement (IAPM) in relation to pre- and intra-operative diagnostic methods for assessing superior mesenteric artery (SMA) stenosis in patients with a diagnosis of chronic mesenteric…
Kain ZE, Schuurman E, Baez-Navarro X et al. · 2026 · Laboratory investigation; a journal of technical methods and pathology
Purpose HER2-low breast cancer has gained clinical relevance owing to the efficacy of trastuzumab deruxtecan. However, variability in detecting low HER2 expression may affect patient eligibility. This nationwide study in the Netherlands…
Rasmussen LS, Alstrup A, Markussen L et al. · 2026 · Military medicine
Introduction A run test is used in the assessment of physical fitness in military applicants. Seismocardiography is a fast, non-invasive method for estimation of cardiorespiratory fitness which could replace conventional run tests. We…
Psenicka O, Brutvan T, Vitkova H et al. · 2026 · Preprint
Abstract Background : Systemic inflammatory response syndrome (SIRS) is associated with changes in muscle metabolism. Resulting muscle weakness is linked with adverse outcomes, e.g. prolonged mechanical ventilation, length of hospital stay…
Brilli D, Giansanti M, Bertoldo S et al. · 2026 · International journal of computerized dentistry
Aim The aim of the present study was to evaluate the accuracy of dynamic navigation (DN) in miniscrew insertion in the palatal vault by comparing the deviation between planned and placed miniscrew positions. The secondary outcome was to…
Nasr A, Hourani R, Ghzayel L et al. · 2026 · The Laryngoscope
Objective To analyze the correlation between vocal tract fat volume and patient tolerance to office-based laryngeal surgery using the transnasal approach. Methods The medical records and video recordings of all patients who underwent…
Itagaki T, Ueki Y, Oyama Y et al. · 2026 · Scientific reports
Achilles tendon (AT) xanthomas are characteristic manifestations of familial hypercholesterolemia (FH). Although soft X-ray radiography (XR) and ultrasonography (US) are used to assess AT thickness, data comparing their diagnostic…
Madini S, Suresh TN, Kattepur AK · 2026 · Cureus
Introduction Epithelial ovarian carcinoma usually has TP53 expression. The TP53 gene is the most frequently mutated gene in ovarian cancer and therapies targeting these mutations may improve treatment outcomes, but there are only few…
He J, Xu G, Zhao J et al. · 2026 · Biology of sex differences
Background Overwhelming evidence shows that obesity is associated with brain structural alterations in young adults. However, the specific sex related changes in obesity and their associated with crystallized intelligence still remained…
Nalwa A, Visakhan A, Elhence PA et al. · 2026 · Indian journal of surgical oncology
Programmed cell death ligand-1 (PD-L1) is involved in T-cell regulation by acting as an immune checkpoint inhibitor, and its expression is being widely studied in various malignancies. The following study was designed to examine the role…
Rizvanoglu İH · 2026 · Foot & ankle orthopaedics
Background Osteochondral lesions of the talus (OLT) represent a challenging ankle pathology that may lead to persistent pain, functional impairment, and progressive joint degeneration. Open transmalleolar osteochondral autograft transfer…
Mhlana A, Milanes-Rodriguez G, Olojede SO et al. · 2026 · BMC endocrine disorders
Background Sleep is essential for maintaining the body's balance, particularly in regulating the Hypothalamic-pituitary-adrenal (HPA) axis, which controls cortisol, the main stress hormone. Cortisol follows a daily rhythm, but irregular…
Doğantekin E, Albayrak F, Doğantekin A et al. · 2026 · Preprint
Introduction: Microbiota refers to all microorganisms colonising the body, whereas microbiome is a broader term covering the genetic material and ecosystem of this population. The skin is the largest organ of the body with a skin…
Mizuta I, Yamashita F, Sutoh Y et al. · 2026 · Geriatrics & gerontology international
Aim Cerebral small vessel disease (CSVD)-related MRI findings, including white matter hyperintensities (WMHs), are not rare in general elderly populations. The aim of this study was to elucidate the contribution of hereditary CSVD-related…
Iturregui C, Liu CC, Carter RT et al. · 2026 · Veterinary ophthalmology
Justification Circadian variations in central corneal thickness (CCT) and their correlation with intraocular pressure (IOP) have not been reported in horses. This information may be clinically relevant when interpreting IOP readings.…
Samim M, Jardon M, Vonck C et al. · 2026 · Journal of orthopaedics
Purpose To assess correlation of pre-operative symptoms, labral damage and chondrolabral junction pathology on MRI with intra-operative findings in patients undergoing hip arthroscopy for femoroacetabular impingement (FAI). Methods…
Santo B, Romanello M, De Franco P et al. · 2026 · Journal of clinical medicine
Background/Objectives: The neutrophil-to-lymphocyte ratio (NLR) is a simple biomarker reflecting systemic inflammatory status and has been investigated in head and neck cancer (HNC) as a potential prognostic indicator. Its role in relation…
Melek Ş, Orhun ÖT, Şenocak MG et al. · 2026 · The Journal of small animal practice
Objectives The present study evaluated the accuracy and agreement of heart rate and peripheral oxygen saturation measurements obtained using the Owlet Smart Sock in awake dogs with low activity levels, using a veterinary patient monitor as…
Li C, Liu s · 2026 · Preprint
Abstract Objective: This study aims to investigate the dynamic evolution patterns of regional ventilation parameters monitored by bedside electrical impedance tomography (EIT) in pediatric patients with acute respiratory distress syndrome…
SUHA BK · 2026 · Preprint
Abstract This study aims to determine the relationship between the moral intelligence of intensive care nurses and their attitudes towards medical errors. The study was designed as a descriptive, cross-sectional study. The study sample…
shoabjareh ME, Ansari-Astaneh M, Shoeibi N et al. · 2026 · Preprint
Abstract Background This study evaluated choroidal thickness in healthy Iranian individuals using enhanced depth imaging optical coherence tomography (EDI-OCT) and evaluated its correlation with demographic characteristics, laboratory test…
Alves TG, Bonadiman EA, Ruiz DC et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem Periapical radiographs have been the primary adjunctive diagnostic method of evaluating abutment-prosthesis misfit. However, whether different radiographic receptor‑holders interfere with diagnostic accuracy depending…