A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20240 results in Negative / Null Result Report · page 341 of 675
SHEN Z, LIU Y, LIU Y et al. · 2025 · Preprint
Abstract Purpose To analyze the clinical features of ocular surface diseases caused by Epstein-Barr virus (EBV) infection. Methods A retrospective case series study was conducted. Data from 48 patients (54 eyes) with EBV infection who…
Zhang C, Xie C, Zhang Z et al. · 2026 · Pathogens (Basel, Switzerland)
Background Sepsis, a life-threatening organ dysfunction caused by dysregulated host responses to infection, frequently involves impaired macrophage efferocytosis that leads to apoptotic cell accumulation, secondary necrosis, and persistent…
Ito K, Hiranaka T, Basaqr AA et al. · 2026 · Orthopaedics & traumatology, surgery & research : OTSR
Background Kinematic alignment (KA) aims to restore the distal and posterior joint surfaces by matching the resected bone to the implant thickness. However, whether KA also accurately reproduces the anterior femoral anatomy, including the…
Barman Kakil Ş, Sarı SA, Hazar L · 2026 · Current eye research
Purpose To evaluate retinal and optic nerve head microcirculation in children with dyslexia using optical coherence tomography angiography (OCTA) and to explore whether retinal microvascular parameters differ between dyslexic and typically…
Jiang C, Cheng P, Liu Y et al. · 2025 · Journal of pediatric orthopedics
Introduction Imaging-based measurement indices of patellar height are essential for diagnosing patella alta in children and adolescents. The Patellotrochlear Index (PTI) measures the cartilaginous anatomy which is crucial for identifying…
Gül O, Ayazoglu MA, Yazıcı A et al. · 2026 · Journal of shoulder and elbow surgery
Background Perianchor fluid collection may differ according to anchor material following arthroscopic rotator cuff repair (ARCR), but its relationship with tendon healing remains unclear. This study aimed to compare perianchor fluid…
Kocak OF, Alpayci M, Demir CY et al. · 2025 · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Objective To determine the frequency and severity of joint hypermobility (JH) in rhinoplasty patients and to assess rhinoplasty satisfaction in rhinoplasty cases with JH. Study design Comparative cross-sectional study. Place and Duration…
Alsayegh MMA, Sallom BA, Fadel EA et al. · 2026 · Scientific reports
Prenatal exposure to trace metal elements remains a significant public health concern, particularly because these elements can cross the placental barrier and accumulate in fetal tissues. Meconium and neonatal hair are commonly used as…
Menxhiqi L, Marinova G · 2026 · Preprint
In a closed-inventory Large Language Model (LLM) system such as Online-CADCOM, which recommends engineering tools from a verified inventory, mention-level hallucination occurs when the model recommends tools not present in the inventory.…
Öztürk G, Orhon F, Bayrakoğlu D et al. · 2026 · International archives of allergy and immunology
The severity and incidence of invasive pneumococcal infections increase in inborn errors of immunities. However, there are limited number of studies in the literature evaluating pneumococcal antibody levels in patients with a prediagnosis…
Ferrara M, Maccario V, Fantino S et al. · 2026 · Preprint
This study investigates intracellular (IC) exposure to tenofovir alafenamide (TAF) and its clinical determinants in experienced people living with HIV. We conducted a monocentric retrospective analysis of 86 adults treated with either…
Abdelaziz AW, Alkherkhisy MM, El-Sheikh HR et al. · 2026 · BMC psychiatry
Background Lipid metabolism and its regulatory molecules, especially adipokines, have gained significant attention in recent pathogenesis research of autism spectrum disorder (ASD). Aims To evaluate serum fatty acid-binding protein 4…
Babadzhanova E, Tilov B, Davcheva D et al. · 2026 · Preprint
Abstract Background Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with metabolic disturbances, including insulin resistance and obesity, chronic anovulation and impaired fertility. Its pathogenesis is complex…
Zhang D, Eurich J, Pitz-Goncalves L et al. · 2026 · Journal of orthopaedic trauma
Objectives To determine the rate of occult vascular abnormalities in high-energy tibial plateau fractures using Computed Tomography Angiography (CTA). Methods Design Prospective Cohort Study. Setting Single Academic Level I Trauma Center.…
Bilen YE, Sinanoğlu N, Külekci Ç · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Purpose Total laryngectomy disrupts nasal airflow, often resulting in significant olfactory and gustatory dysfunction. While these sensory losses may adversely affect patients' quality of life and psychological well-being, they typically…
Akıncıoğlu P, Dağlı Ü, Koca E · 2026 · The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
Background/aims Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a chronic inflammatory disorder commonly associated with iron deficiency anemia and anemia of chronic disease. Hepcidin is a key…
Cigdem-Karacay B, Bayramoglu-Demirdogen E, Konar NM et al. · 2026 · Irish journal of medical science
AIM: The effectiveness of EMG-BF in SUI has not yet been proven. This study aimed to the effectiveness of EMG-BF on pelvic floor muscle activity, pad test, severity of complaints, and quality of life in female patients with Stress Urinary…
Gosset M, Coquart A, Delaval B et al. · 2026 · Journal of strength and conditioning research
Abstract Gosset, M, Coquart, A, Delaval, B, Catalano, J, Huou, G, Boufflers, M, Bozok, D, Bellanger, L, Douchet, T, Viroux, P, Jaffré, C, and Abaïdia, A-E. Compression garments and adaptations to plyometric training in soccer players: A…
Fernando H, Vito I, Santillan N et al. · 2026 · Journal of neuroendocrinology
As peptide receptor radionuclide therapy (PRRT) maintains a key role in the treatment of neuroendocrine tumours (NETs), there is growing recognition of the importance of evaluating patient-reported health related quality of life (HRQoL).…
Ikuma H, Hirose T, Kawasaki K et al. · 2026 · Acta medica Okayama
We evaluated the clinical outcomes and limitations of anterior and posterior combined surgery with a mini-open corpectomy applying an expandable cage (Xcore®) and percutaneous pedicle screw (PPS) fixation using single-position surgery in…
Patil S, Raju KN, S Kotnoor S et al. · 2026 · Bioinformation
The additional clinical benefit of diode laser irradiation as an adjunct to open flap debridement (OFD) in the treatment of chronic periodontitis remains uncertain. Therefore, it is of interest to evaluate the impact of diode laser…
Pimouguet C, Kret M, Francis-Oliviero F et al. · 2026 · Journal of Alzheimer's disease : JAD
BackgroundThere is increasing interest in non-pharmacological approaches to address the needs of patients with Alzheimer's disease and other dementia. However, previous research highlighted the need to adapt interventions to the healthcare…
Hansel NN, Putcha N, Woo H et al. · 2026 · American journal of respiratory and critical care medicine
Rationale Indoor particulate matter (PM) is linked to worse respiratory outcomes in adults with chronic obstructive -pulmonary disease (COPD). It is unclear if reducing indoor pollutants can improve respiratory health among current…
Wong ECH, Lo RWM, Kwan RLC et al. · 2026 · Healthcare (Basel, Switzerland)
Background : COVID-19 can have adverse effects on individuals' lung functions for up to 6 months or more after the episode. As a result, people may be reluctant to exercise, and this can have further adverse effects on their lung capacity…
Xie E, He Y, Cao T et al. · 2026 · Preprint
Abstract Background BOPPPS, which comprises six components—Bridge-in, Objective, Pre-assessment, Participatory Learning, Post-assessment, and Summary—is a student-centered structured teaching model widely applied in theoretical courses.…
Maldonado DR, Schab AR, Sikligar D et al. · 2026 · Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
Purposes To compare minimum 2-year patient-reported outcomes measures (PROMs) between adolescents undergoing primary and revision hip arthroscopy. Methods Data were prospectively collected and retrospectively reviewed for adolescents who…
Topan YE, Bayar Muluk N, Yavuz R et al. · 2026 · The Journal of craniofacial surgery
Objective To determine whether biological therapy is a viable option for individuals with recurrent chronic rhinosinusitis with nasal polyps (CRSwNP), we will assess the clinical outcomes of maximal conventional therapy (MCT). Methods For…
Da Costa M, Seitz B, Munteanu C et al. · 2026 · Die Ophthalmologie
Background In Germany, each surgical corneal center defines individual criteria for the indications for Descemet membrane endothelial keratoplasty (DMEK). Clinical experience shows a clear discrepancy between best corrected visual activity…
Eldesoqui M, Al-Batati A, Erfan OS et al. · 2026 · Clinical anatomy (New York, N.Y.)
Generation Z has different requirements, problems, expectations, and attitudes that they bring into the educational environment. Teachers have unprecedented challenges in addressing their needs and aspirations. Gamification involves…
Jia Y, Dong Y, Jiang R et al. · 2026 · Journal of pediatric orthopedics
Background Sprengel deformity is a rare congenital malformation of the scapula. To date, there have been limited reports analyzing the clinical outcomes of the modified Woodward procedure and conservative management in the treatment of…