A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19850 results in Negative / Null Result Report · page 339 of 662
Bregulla M, Packheiser J, Merz CJ et al. · 2026 · Scientific reports
Episodic memories can be shaped by various contextual factors. While social and sensory cues such as odors and music have been shown to influence encoding and retrieval, the role of tactile information remains unclear. In this…
Marinello WP, Zylka MJ · 2026 · Frontiers in toxicology
Introduction Per- and polyfluoroalkyl substances (PFAS), particularly perfluorooctanoic acid (PFOA), are persistent environmental contaminants known for bioaccumulation and adverse health effects, including neurodevelopmental toxicity.…
Parhizmeymandi N, Azimi R, Sanjari MA et al. · 2026 · Motor control
Muscular fatigue often induces compensatory adjustments-such as increased motor unit recruitment and synchronization-that can elevate kinematic variability. By contrast, mental fatigue alters top-down neural control, modulates…
McGlynn M, Steffes LC, Shah A et al. · 2026 · Preprint
Pulmonary arterial hypertension is a progressive, fatal disease driven by pathologic vascular remodeling including arterial medial hypertrophy, occlusive neointimal lesion formation, and venous muscularization. Current vasodilatory…
Albanna RH, El-Farraj H, Awawdeh S et al. · 2026 · Preprint
Abstract Apical debris extrusion is an unavoidable phenomenon; however, evidence remains limited regarding the effect of newer motion kinematics, specifically counterclockwise optimum torque reverse (CCW OTR). Sixty-six mandibular molars…
Skondras EV, Kamalakidis SN, Skondra E et al. · 2026 · Preprint
Implant-supported overdentures improve denture retention and patient satisfaction, but debonding of attachment housings from the denture base remains a frequent prosthetic complication. This in vitro study evaluated the influence of…
Belenger M, Dumont C, Geelhand P et al. · 2026 · Journal of speech, language, and hearing research : JSLHR
Purpose We investigated sex differences in the production of pauses in autistic (pre-)adolescents in two conversational contexts: a monologue and an interactive discussion. Method This study included 107 French-speaking participants ( M…
Zhang M, Chai X, Zhang X et al. · 2026 · Annals of hematology
Chimeric antigen receptor T cells (CAR-T cells) have been widely applied in hematologic malignancies. It has shown limited efficacy in the treatment of myeloid neoplasms. We retrospectively analyzed the safety and efficacy of CD123 CAR-T…
Seeger J, Henke NA · 2026 · Preprint
Astaxanthin can be derived from different sources such as petrochemical synthesis, natural sourcing from green algae or by microbial fermentation. As one of the strongest antioxidants known by nature, astaxanthin is rising attention as an…
Szulim D, Kucharska E, Machalińska A et al. · 2026 · Nutrients
Background/Objectives : Age-related macular degeneration (AMD) is a leading cause of permanent deterioration of central vision in elderly people. While anti-VEGF therapy remains the standard of care for neovascular AMD, disease progression…
Osorio-Vasco J, Rojas-Mora J, Barrera-Causil C et al. · 2026 · Work (Reading, Mass.)
BackgroundStanding work is common across a wide range of industries and service sectors and has been associated with the development of low back pain.ObjectiveTo analyze changes in low back pain across eight experimental scenarios…
Suttles S, Boeth RR, Frazier M et al. · 2026 · Military medicine
Objective Describe an innovative Sports Medicine clinic design implemented in an outpatient Physical Therapy (PT) clinic within a Military Treatment Facility (MTF) for both referral and direct access (DA) entry portal pathways, and to…
Ramezani A, Rahimi S, Soltani A et al. · 2026 · Preprint
Abstract Background : Chronic pain is highly prevalent among older adults and has been shown to be associated with differences in cognitive function. While pain intensity reflects the severity of pain, pain interference assesses the extent…
Yılmaz A, Kurt D · 2026 · BMC pregnancy and childbirth
Objective To evaluate systemic immune-inflammatory biomarkers in patients diagnosed with eclampsia and to investigate their potential association with inflammation. Methods This retrospective study included 31 patients with eclampsia and…
Chen G, Jiang L · 2026 · Preprint
Abstract How do contentious implementation processes reshape political trust in multi-level governance systems? This article examines this question through the case of land expropriation in China, a policy domain marked by visible local…
Lengerli Efe A, Özen Sütüven E, Uçar Y et al. · 2026 · International journal of computerized dentistry
Aim The aim was to evaluate the effect of hydrogen peroxide disinfectant exposure for 60 minutes -representing the longest exposure time recommended for achieving the widest antimicrobial spectrum- on the flexural strength (FS) of…
Hwang I, Yun S, Park J · 2026 · Scientific reports
The present study investigates the human haptic perception of 2.5D dome-shaped surface features in terms of difference and absolute thresholds. We conducted two experiments to measure the thresholds, analyzing the effect of sample base…
Zayas-Bórquez R, Diaz-Barrientos CZ, Canto-Losa J et al. · 2026 · Revista de gastroenterologia de Mexico (English)
Introduction and aims Hemorrhoidal disease is a common condition and may affect quality of life. Although it tends to respond to conservative treatment, some cases require surgery. The present study examined clinical and demographic…
Yaman İ, Korkmaz H, Akağaç AE et al. · 2026 · Journal of cardiovascular development and disease
Background Pulmonary arterial hypertension (PAH) is a rare and progressive disorder characterized by increased pulmonary vascular resistance and vascular remodeling. Genetic polymorphisms, epigenetic modifications, and ion channel…
Yılmaz A, Gokturk I · 2026 · Preprint
Abstract Background Eyelid tumors represent a broad and heterogeneous group of lesions arising from various periocular structures, including the epidermis, adnexal glands, and stromal tissues. Although the majority of these lesions are…
Jahangeer A, Jabeen R, Fatima S et al. · 2026 · BMC endocrine disorders
Background Thyroid dysfunction and Helicobacter pylori (H. pylori) infection are both highly prevalent in Pakistan. Several studies have proposed a potential immunological link between H. pylori infection and autoimmune thyroid disease,…
Elmetwally AA, Khashaba MH, Wagih HM et al. · 2026 · Diagnostic pathology
BACKGROUND: Thyroid carcinoma is a common tumor affecting the Egyptian population accounting for 2% of newly diagnosed cases of cancer in Egypt yearly and constituting 7.73% of 5 year prevalence in Egypt. Stomatin-Like Protein 2 (SLP-2)…
Ozden Sertcelik U, Turker M, Sertcelik A et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Perspectives : Obstructive sleep apnea (OSA) is a prevalent condition associated with increased perioperative risks. Endobronchial ultrasound (EBUS), a diagnostic and staging procedure requiring deep sedation, may pose…
Bakay H, Kılavuz FA · 2026 · Psychopharmacology
Rationale Systemic inflammation is increasingly recognized as a key component of the pathophysiology and neuroprogression of bipolar disorder (BD). Novel hematologic indices, including the NLR, PLR, SII, SIRI, and PIV, provide accessible…
Tian X, Jiang T, Lei Y et al. · 2026 · The American surgeon
BackgroundSphincter-preserving surgery for low rectal cancer is challenging. The double stapling technique (DST) and modified Bacon procedure are commonly used, but their differences in postoperative functional recovery, complication…
Umudova K, Demir Ö · 2026 · BMC women's health
Introduction and hypothesis Post-void residual (PVR) urine volume is routinely evaluated in women with urinary incontinence and/or pelvic organ prolapse (POP). However, its clinical relevance in postmenopausal women without these…
Henriques Cavalcanti Torres de Melo R, de Barros Silva PG, Neto HFEC et al. · 2026 · World journal of surgical oncology
Introduction Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide, with up to 50% of patients developing metastatic disease, predominantly involving the liver. Hepatectomy remains the gold standard for resectable…
Karlin NJ · 2026 · Psychological reports
Given the unique challenges faced by frontier aging older adults, such as limited access to healthcare and social services, the potential for different functional disabilities as compared to rural older adults exists. By comparing frontier…
Aghdasi Z, Negahban H, Movahedi Aliabadi M et al. · 2026 · The Journal of manual & manipulative therapy
Background Lumbar disc herniation (LDH) is a leading causes of low back pain (LBP). Conservative approaches, such as the McKenzie Method of Mechanical Diagnosis and Therapy (MDT), are widely used as first-line treatments. MDT is based on…
Park S, Shin JH, Moon WJ et al. · 2026 · Medicine
It is important to identify the origin of ultrasonographic punctate echogenic foci (PEF), which represent microcalcifications, in cervical lymph nodes (LNs). This study aimed to explore the malignancy rate of LNs with PEF and investigate…