A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19850 results in Negative / Null Result Report · page 337 of 662
Liu W, Gan Y, Gu Q et al. · 2026 · BMC medical education
Objective To evaluate the effectiveness of digital pathology technology in the standardized residency training (SRT) in clinical pathology, compare the performance differences between digital slide-based and traditional microscope-based…
Gu XY, Cao JF, Zhang XY et al. · 2026 · Drug design, development and therapy
Objective This trial aimed to compare the effects of alfentanil and sufentanil on postoperative nausea and vomiting (PONV) in patients at moderate-to-high risk undergoing sedated gastrointestinal endoscopy. Methods Two hundred and eighteen…
Soleimani S, Pirhadi S, Jadidi K et al. · 2026 · International ophthalmology
Purpose To compare the visual, refractive, corneal curvature, and aberrometry outcomes one year following implantation of two intra-stromal corneal rings (ICRS) with different cross-sectional designs. Methods This retrospective…
Kurt Akgül Ş, Boylu ÖF · 2026 · Surgical and radiologic anatomy : SRA
PURPOSE: Mandibular hypomobility is a condition in which the jaw joint is restricted due to various causes, including temporomandibular joint disorders (TMD), ankylosis, head and neck infections and tumors, coronoid processes hyperplasia…
Sumner SM, Naskou MC · 2026 · Frontiers in veterinary science
Introduction Platelet-rich plasma (PRP) and platelet lysate (PL) are biologically active products used in regenerative medicine because of their high concentrations of growth factors, cytokines, and other bioactive molecules that promote…
Wang K, Chen Y, Fu H et al. · 2026 · American journal of translational research
Objective To compare the clinical efficacy of four root canal filling materials for the treatment of chronic periapical periodontitis. Methods The clinical data of 200 patients with chronic periapical periodontitis from January 2023 to…
Boudreau C, Couture M, Rousseau-Saine N et al. · 2026 · BMC anesthesiology
Introduction Glucagon-like peptide-1 receptor agonists (GLP-1 RA) are now increasingly used for glycemic control in type 2 diabetes mellitus as well as for weight loss. Their effect on gastric emptying may increase the risk of aspiration…
Adamowitsch N, Reiterer C, Fleischmann E et al. · 2026 · Scientific reports
Volatile anesthetics modulate inflammatory responses, but it remains unclear whether desflurane and sevoflurane differ in their effects on postoperative inflammation. We evaluated in this secondary analysis of a prospective randomized…
Gianaris A, Ramalho MO, de Oliveira AA et al. · 2026 · Neotropical entomology
Historically, studies have sought to identify host-specific factors in host-microbe interactions as a means of understanding evolutionary success. The genus Atta, comprising leaf-cutter ants, is native to the southern Neotropics and…
Zhang J, Liang J, Lv F et al. · 2026 · Practical laboratory medicine
Objective To investigate the distribution characteristics of potential high-risk pathogens for early-onset neonatal infection in maternal vaginal secretions, and to perform a head-to-head comparative evaluation of detection performance for…
Pabarjay M, Azarfarin R, Alizadeh-Ghavidel A et al. · 2026 · BMC anesthesiology
Background Ultrafiltration is integral to cardiopulmonary bypass, yet the optimal replacement fluid for zero-balance ultrafiltration requires further investigation to guide clinical practice. This study aimed to compare the efficacy of…
Meng C, Deng X, Yang Y et al. · 2026 · BMC musculoskeletal disorders
Background There is still debate regarding whether the remnant tendon on the greater tuberosity should be removed during rotator cuff repair (RCR). This study aimed to evaluate whether remnant preservation (RP) in RCR leads to better…
Abd Allah DAE, Abdelfattah AM, Nawar NH et al. · 2026 · The Journal of prosthetic dentistry
Statement of problem The effect of integrating facial scans into digital planning on the accuracy of placement of dental implants and the preplanned interim prosthesis in maxillary complete arch implant rehabilitations has not been clearly…
Xu Y, Czajkowski M, Hanley N et al. · 2025 · Ecological economics
A large literature in behavioral science suggests that people's emotional condition can have an impact on their choices. We consider how people's emotions affect their stated preferences and willingness to pay for changes in environmental…
Koutsonida M, Markozannes G, Kanellopoulou A et al. · 2026 · Preprint
Background: Metabolic syndrome (MetS) has been associated with cognitive decline. Considering its increasing prevalence worldwide, the goal of this study was to evaluate the feasibility and efficacy of a short-term, self-administered…
Ding L, He M, Zhu Y et al. · 2026 · Scientific reports
Pregnancy emotional states can influence postpartum colostrum delivery, and lactational capacity establishes 1-5 days postpartum. Breast milk production capacity is key to promoting breastfeeding. This study applied positive psychology…
Chern CWJ, Cheng LJ, Chiang GSW et al. · 2026 · Age and ageing
Background Physio-cognitive dual-task training (PCDT), combining physical and cognitive tasks, is a promising approach. However, clarity regarding its effectiveness and evidence credibility remains limited. Objective To evaluate PCDT…
Chandi JK, Nandi K, Biswas RK et al. · 2026 · BMJ case reports
Idiopathic vascular epiretinal membrane (ERM) is a macular disorder which is an extremely rare entity. A hypertensive male in his early 50s presented with complaints of distortion and diminished vision in the left eye. Fundus examination…
Ali MAA, Zeitoun MM, Ebeid TA et al. · 2026 · Preprint
Abstract This study aims to investigate the roles of adding oleuropein and two types of monosaccharides on the post-thaw bull semen characteristics. Semen was collected from five Brown Swiss bulls twice a week for 16 weeks. Two experiments…
Shayan SK, Abbood RS, Al-Taie SF et al. · 2026 · Pharmacology research & perspectives
Cardiovascular diseases (CVD) remain to impose a main global burden of morbidity and mortality despite advances in anticipation and treatment. Omega-3 fatty acids, mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have…
Wildhagen S, Rechlin J, Kocaöz G et al. · 2026 · Journal of dentistry
Objectives The aim of this in vitro study was to evaluate the scanning accuracy of two intraoral scanners at different post-preparation depths and diameters, using micro-computed tomography (µ-CT) data as the reference standard. Methods…
Enow AMH · 2026 · Preprint
Abstract This study empirically examines the impact of import dependence, gross capital formation, and population growth on Somalia's gross domestic product (GDP) from 1991 to 2023—a period encompassing state collapse, prolonged conflict,…
Prihanti GS, Firmansyah FH · 2026 · Frontiers in medicine
Introduction This study aimed to assess medical students' perceptions of spiritual care using a culturally adapted Muslim-context version of the Spirituality and Spiritual Care Rating Scale (SSCRS). Methods A cross-sectional study was…
Aydin MA, Aydoğdu NG, Kizilarslan V et al. · 2026 · Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society
Background This study was conducted to examine the mediating role of eudaimonic well-being in the effect of perceived poverty on quality of life in the elderly. Methods This descriptive cross-sectional study was conducted with 523 elderly…
Li Y, Wang Z, Xu T et al. · 2026 · BMC plant biology
Arbuscular mycorrhizal (AM) fungi can effectively enhance the photosynthesis and antioxidant capacity of plants under cadmium stress; however, the underlying regulatory mechanisms remain poorly understood. This study focuses on the…
Duarte ABA, Dias-Silva TP, Viana WCC et al. · 2026 · Tropical animal health and production
The aim of this study was to evaluate the effect of xylanase addition (1.8 g/kg dry matter [DM]) to tropical grass haylage used in total mixed rations (TMR) on in vitro organic matter degradability, ruminal fermentation kinetics, and…
Abbasi S, Akbari N, Yazdani M et al. · 2026 · Artificial cells, nanomedicine, and biotechnology
Ex vivo expansion of human adipose-derived stem cells (hADSCs) remains challenging because reduced-serum culture conditions can compromise short-term cell function. Here, we evaluated a microenvironment-inspired tri-component…
Özkar B, Söylemez E · 2026 · Neurological research
Objective Previous studies evaluating central auditory processing in migraine have used conventional tests, but the findings have remained inconsistent. This study aimed to assess the central auditory abilities of individuals with migraine…
Ray S, Bhutia E, Meena RK · 2025 · Cureus
Background In recent years, the rise of digital technology has led to a significant increase in screen time among children, raising concerns about the potential effects of excessive screen exposure on children's development. The objectives…
Tayebi SM, Mirzaei M, Stout JR · 2026 · Journal of the International Society of Sports Nutrition
Purpose High-intensity judo bouts induce oxidative stress and muscle damage, impairing recovery. This randomized, double-blind, placebo-controlled pilot trial examined whether acute β -hydroxy- β -methylbutyrate free acid (HMB-FA)…