Negative / Null Result ReportMedicine
Yahanda AT, Joseph K, Bui TT et al. · 2026 · Spine deformity
Purpose Surgical corrections for adult spinal deformity (ASD) often extend from T4-pelvis. Certain patients may require fusion from C2-pelvis. Comparisons are necessary to guide surgical decision-making, particularly for frailer patients…
View details →DOI: 10.1007/s43390-026-01490-z Negative / Null Result Report
Xu P, Li Y, Chen Y et al. · 2026 · Preprint
Background: Moderate-to-severe preterm brain injury (PBI), including intraventricular hemorrhage (IVH) and periventricular leukomalacia (PVL), remains an important cause of adverse neurodevelopmental outcomes in preterm infants. Early risk…
View details →DOI: 10.20944/preprints202606.0340.v1 Negative / Null Result Report
Mitchell WJ, Schmidt H, Moughan E et al. · 2026 · Preprint
Continuous self-report during ongoing experience provides a high-resolution window into subjective processing, yet concerns that it may disrupt the neural and cognitive processes being measured have limited its use in neuroimaging. We…
View details →DOI: 10.31234/osf.io/rhd9u_v1 Negative / Null Result ReportMedicine
Ziva A, Ziori E, Pothos EM · 2026 · Quarterly journal of experimental psychology (2006)
Implicit (unconscious) learning ostensibly affects cognitive and social skills in both typical and atypical populations, such as those on the autism spectrum. Research into implicit learning in autism has yielded conflicting results,…
View details →DOI: 10.1177/17470218261446884 Negative / Null Result ReportOpen accessMedicine
Newman EL, Mashanova-Galikova I, Tiganj Z et al. · 2026 · Hippocampus
Spatial tuning is a hallmark property of neural firing in the hippocampal formation. Yet, that tuning is often less well correlated with the instantaneous current position of an animal than it is with an integrated version of the past or…
View details →DOI: 10.1002/hipo.70110 Negative / Null Result ReportMedicine
Agboola OE, Agboola SS, Shaleye AB et al. · 2026 · Journal of molecular graphics & modelling
Predicting drug-target interactions computationally is a practical strategy for prioritizing candidate compounds in early drug discovery, but the reliability of published models is often limited by small resampled datasets, warm-only…
View details →DOI: 10.1016/j.jmgm.2026.109461 Negative / Null Result ReportMedicine
Ramos MN, Bedore LM, Peña ED · 2026 · American journal of speech-language pathology
Purpose This study examines the diagnostic accuracy of four measures derived from English narrative language samples for identifying developmental language disorder (DLD) in 5- and 6-year-old Spanish-English bilinguals. Method Ninety-two…
View details →DOI: 10.1044/2025_ajslp-25-00182 Negative / Null Result ReportMedicine
Blanco-Moreno C, Bippus AC, Tomescu AMF · 2026 · Annals of botany
Background and aims The bryophyte fossil record is less abundant and diverse than predicted by the age of the group and as compared to the fossil record of younger plant groups. Taphonomic biases explain only partially its scarcity. Here,…
View details →DOI: 10.1093/aob/mcaf070 Negative / Null Result ReportMedicine
Ashouri R, Reynolds PS, Rajavel S et al. · 2026 · Urology
Objective To guide biopsy decision making via a predictive model for clinically significant prostate cancer (csPCa) in men with positive imaging (PI-RADS 3-5). We aim to elucidate the influence of zone on the predictive accuracy of PI-RADS…
View details →DOI: 10.1016/j.urology.2026.01.028 Negative / Null Result ReportOpen accessMedicine
Christianson G, Howard ZM, Kenney S et al. · 2026 · mAbs
The use of animal models that can reliably predict drug performance in human patients is critical to antibody therapeutic development. Along with assessing toxicity and efficacy, determining the pharmacokinetic (PK) properties of…
View details →DOI: 10.1080/19420862.2026.2649990 Negative / Null Result ReportMedicine
Lutfi W, Desai ND, Pan Z et al. · 2026 · The Annals of thoracic surgery
Background The choice between bioprosthetic or mechanical surgical aortic valve replacement (SAVR) for dialysis patients is debated. Rapid adoption of transcatheter aortic valve replacement (TAVR) complicates decision-making further. This…
View details →DOI: 10.1016/j.athoracsur.2026.03.007 Negative / Null Result Report
Keskinel I, Eryilmaz M, Diktas Tahtasakal S · 2026 · Preprint
Objectives: Streptococcus pneumoniae is a major respiratory pathogen. Reports during the COVID-19 era suggest decreased pneumococcal activity. This study aimed to assess the frequency of S. pneumoniae in adult sputum cultures and its…
View details →DOI: 10.20944/preprints202606.0633.v1 Negative / Null Result ReportMedicine
Akmansoy ŞC, Kahramanoğlu E · 2026 · Journal of oral science
Purpose This study compares the marginal and internal gaps for four restorative materials produced by two fabrication methods in both minimally invasive occlusal veneer and conventional onlay cavities. Methods Eighty mandibular molars…
View details →DOI: 10.2334/josnusd.25-0348 Negative / Null Result ReportMedicine
Xie J, Song Z, Fang W et al. · 2026 · Naunyn-Schmiedeberg's archives of pharmacology
This study aimed to elucidate the potential molecular mechanisms by which artificial sweeteners contribute to the initiation and progression of atherosclerosis, with the goal of providing a theoretical basis for the safety evaluation of…
View details →DOI: 10.1007/s00210-026-05241-9 Negative / Null Result ReportMedicine
Robinson E, Chapman C, Orchard F et al. · 2026 · Journal of child and adolescent mental health
Background: Exposure of children and young people to potentially traumatic events is common. There is a need for increased access to early interventions following a potentially traumatic event. Objective: This review aimed to identify…
View details →DOI: 10.2989/17280583.2025.2581754 Negative / Null Result Report
Ross SR, Suzuki H, Urabe J et al. · 2026 · Preprint
1 Ecosystem functioning can be maintained in species-rich communities even under fairly severe perturbations. This is because communities with high richness include variation both in species’ functional roles ( functional diversity ) and…
View details →DOI: 10.64898/2026.06.19.733370 Negative / Null Result ReportMedicine
Zheng, Jia, Jing et al. · 2026 · International journal of cancer
This single-center retrospective study evaluated radiation pneumonitis (RP) in 209 treatment-naive EGFR-mutant non-small cell lung cancer (NSCLC) patients receiving first-line third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs)…
View details →DOI: 10.1002/ijc.70630 Negative / Null Result ReportMedicine
Ng Fat, West, E Jackson · 2026 · BMJ public health
Stopping tobacco smoking, reducing alcohol consumption from high-risk levels, increasing physical activity and improving diet can improve mental well-being. To gain a preliminary estimate of the potential benefits of healthy lifestyle…
View details →DOI: 10.1136/bmjph-2025-004301 Negative / Null Result ReportMedicine
Karlsson, Ekendahl, Lindner · 2026 · Child and adolescent psychiatry and mental health
Individuals with substance use problems have higher mortality risks than the general population. This study aimed to assess all-cause and specific-cause mortality among adolescents and young adults in specialized substance use treatment in…
View details →DOI: 10.1186/s13034-026-01125-1 Negative / Null Result ReportMedicine
Harmantepe, Canturk, Küçük et al. · 2026 · BMC surgery
Low anterior resection syndrome (LARS) is a frequent functional disorder following sphincter-preserving surgery for rectal cancer. This study aimed to assess the impact of surgical approach and anastomosis distance on LARS development. We…
View details →DOI: 10.1186/s12893-026-03975-0 Negative / Null Result ReportMedicine
Sun, Li, Li et al. · 2026 · Journal of food science
Lead (Pb) exposure is a major environmental risk factor for cognitive impairment. This effect is mainly caused by oxidative stress, mitochondrial dysfunction in the hippocampus, and neuronal apoptosis. This study examined whether black…
View details →DOI: 10.1111/1750-3841.71233 Negative / Null Result ReportMedicine
Manca, Paulus, Almeida et al. · 2026 · Neuroscience
Social connectedness strongly influences health and longevity, and adult pair bonds provide psychological benefits distinct from other social relationships. Oxytocin (OT), corticotropin-releasing hormone (CRH), and opioids play an…
View details →DOI: 10.1016/j.neuroscience.2026.06.028 Negative / Null Result ReportMedicine
Ertürkmen Aru, Büke, Saat et al. · 2026 · Familial cancer
Biallelic loss-of-function variants in NTHL1 are associated with an autosomal recessive cancer predisposition syndrome, whereas the cancer risk associated with monoallelic NTHL1 variants remains uncertain. The recurrent truncating variant…
View details →DOI: 10.1007/s10689-026-00578-9 Negative / Null Result ReportMedicine
Alencar, Teles, Cunha et al. · 2026 · Revista brasileira de ortopedia
Artificial intelligence (AI) tools based on natural language, such as ChatGPT 4.1 mini (OpenAI Group PBC) and Gemini 2.5 Flash (Alphabet Inc.), are used by patients as sources of medical information. The current study aimed to evaluate and…
View details →DOI: 10.1055/s-0046-1820461 Negative / Null Result ReportMedicine
Petrina, Dong, Beamer et al. · 2026 · Open forum infectious diseases
Vaginal dysbiosis is associated with HIV acquisition and preterm delivery. Our objective was to evaluate prevalent vaginal infections, and changes in microbiota and cytokines among pregnant and breastfeeding women from 4 African countries…
View details →DOI: 10.1093/ofid/ofag329 Negative / Null Result ReportMedicine
Hardika, Kurniawan, Laksmi et al. · 2026 · Journal of the ASEAN Federation of Endocrine Societies
Leukocyte telomere length (LTL) is considered a biomarker of cellular senescence. Previous studies have reported the associations between shortened telomere length and type 2 diabetes mellitus (T2DM). However, the role of underlying…
View details →DOI: 10.15605/jafes.041.01.5071 Negative / Null Result ReportMedicine
Durgala, Horvath, Skrabanova et al. · 2026 · Frontiers in behavioral neuroscience
Traumatic brain injury (TBI) is a major health concern in the current population. Animal models are increasingly important for identifying early neurobehavioural changes associated with mild to severe as well as repetitive brain injuries.…
View details →DOI: 10.3389/fnbeh.2026.1839876 Negative / Null Result ReportMedicine
Choi, Park, Song et al. · 2026 · Psychiatry investigation
Although its potential antidepressant effects have been suggested, evidence on long-term outcomes for post-delivery depression remains limited. We evaluated whether peripartum intravenous magnesium sulfate (MgSO₄) is associated with…
View details →DOI: 10.30773/pi.2025.0427 Negative / Null Result ReportMedicine
Lamb, Akulian, Musani et al. · 2026 · Respiratory research
Single chain urokinase (LTI-01) intrapleural enzymatic therapy (IET) was safe and promising in a phase 1 clinical trial to overcome failed drainage in patients with pleural infection. The LTI-01-2001 phase 2a trial was a randomized,…
View details →DOI: 10.1186/s12931-026-03782-4 Negative / Null Result ReportMedicine
Akdogan, Aydin · 2026 · BMC oral health
Data comparing the wear of 3D printed permanent resin (PR) and milled zirconia (Z) to that of primary tooth enamel are limited. This study aimed to investigate the wear behavior of two materials and their effect on antagonist primary…
View details →DOI: 10.1186/s12903-026-08916-0 