A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19850 results in Negative / Null Result Report · page 323 of 662
Huaizhou You (414624), Chuanming Hao (124404), Ying Zhou (25031) et al. · 2013
(a1) Failure plots for probability of survival at 90 days between high and low 25-hydroxyvitamin D level subgroups. No significant difference between the two subgroups was found (log rank, p = 0.554). (b1) Failure plots for probability of…
Partoazar A, Shahabi S, Afrasiabi S · 2026 · BMC oral health
Background Biofilms contribute to the dental calculus formation, which in turn deteriorates oral and systemic health. The use of antimicrobial photodynamic therapy (PDT) may be limited by problems with photosensitizer penetration. In…
Lipa AJ, Janata-Schwatczek K, Sterz M et al. · 2026 · Seminars in thrombosis and hemostasis
Pulmonary embolism (PE) in octogenarians (i.e., patients > 80 years) is associated with substantial morbidity and mortality, yet this population remains underrepresented in major studies. We compared the predictive performance of the…
Chen W, Ge X, Hu C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Prospective studies are necessary to determine the association between circulating proteins and colorectal cancer (CRC) risk, offering non-invasive biomarkers for early CRC risk prediction and interventions. The Olink Explore-3072 platform…
Umer H, Mumtaz T, Weiskirchen R et al. · 2026 · Chronobiology international
Disruption of circadian rhythm is common in rotating shift workers, individuals with jet lag, and people with irregular sleep schedules and contributes to metabolic diseases including obesity, type 2 diabetes, metabolic…
Liu Y, Tao G, Zhao Y et al. · 2026 · Frontiers in medicine
Objective To characterize choroidal structural and perfusion changes in children with emmetropia, low myopia, and moderate myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography…
Kurogochi K, Stern JA, DeFrancesco TC et al. · 2026 · Journal of the American Veterinary Medical Association
Objective The T-wave peak-end (TpTe) interval and its ratio to the QT interval (TpTe:QT) are ECG markers of myocardial repolarization dispersion. We hypothesized that these markers are associated with echocardiographic indices reflecting…
Eydou Z, Garber S, Sikkema M · 2026 · Cureus
Fusobacterium necrophorum is a recognized cause of brain abscesses and has been classically associated with Lemierre syndrome. We report a case of a 17-year-old male patient who presented with seizures, fever, and altered mental status…
Szeto CYY, Kwan HS · 2026 · Preprint
Dietary and lifestyle microbiome interventions often produce mild but heterogeneous remodeling rather than uniform community shifts. In this setting, scalar diversity or group-level summaries can appear weak or inconclusive even when…
Boualia B, Sandeli A, Boulebd H et al. · 2026 · ACS omega
In this research, we present the successful synthesis of benzimidazolium salts ( 2a - e ) and their corresponding selenium-NHC adducts ( 3a - e ), achieved with satisfactory yields ranging from 75% to 88%, and characterized using…
Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science
Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…
Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports
Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…
Wei X, Xue M, Fan B et al. · 2026 · BMC pulmonary medicine
Background Long-term changes in lung function in children with symptom control asthma are rare. To assess the trajectory of pulmonary function in children and analyze the influence factors. Methods The effects of gender, age, Body Mass…
Eltahir M, Young K, Younes S et al. · 2026 · American journal of clinical pathology
Objectives Determination of B-cell clonality in formalin-fixed, paraffin-embedded tissues is challenging, especially in cases where tumor B cells are sparse. Flow cytometry is of limited utility in Hodgkin lymphomas, at least in part due…
Hauck F, Herber V, Moecke S et al. · 2026 · International journal of oral implantology (Berlin, Germany)
Purpose The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established…
Uğurlu İ · 2026 · Journal of clinical laboratory analysis
Background Apelin-13 and Galectin-3 (Gal-3) are bioactive mediators linked to inflammation and cardiometabolic pathways. Their clinical utility in COVID-19 alongside routine laboratory tests remains unclear. Methods In this case-control…
Yang B, Guo Y, Li J et al. · 2026 · Preprint
Abstract Purpose This study presents the first national-scale assessment of heavy metal contamination, ecological risks, and human health implications in paired park surface dust and soil across 40 Chinese cities over a 15 years period…
Rouzic FL, Lacroix J, Ehrmann A et al. · 2026 · Preprint
Abstract Background Several walking tests assess mobility and fall-related function in older adults, but their clinimetric properties remain insufficiently documented across task conditions and assessment environments. Augmented reality…
Qian MY, He LY, Lan P et al. · 2026 · International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
This study aimed to identify predictors of outcomes and evaluate the therapeutic impact of surgical intervention in CM patients, with a specific focus on the growing HIV-negative population in East Asia. We conducted a single-center…
Fang H, Feng L, Gu M et al. · 2026 · Personality and mental health
Invalidating family environments are theorized to undermine youths' emotion socialization and confer risk for psychopathology, yet heterogeneity in how invalidation is expressed within families is rarely examined. This study employed…
Katip A, Demiralp E · 2026 · Toxics
Industrial and domestic wastewaters, nonpoint pollution sources, and climate change affect stream ecosystems, water quantity, and quality. Within the scope of this study, the water quality of Nilüfer Stream was evaluated using the Water…
Takashima K, Kawabe T · 2026 · Preprint
The Medusa effect refers to the cognitive phenomenon in which individuals depicted directly in a photograph (Level 1; L1) are judged as possessing more mind than individuals depicted within a photograph embedded inside another photograph…
Bakhshalizadeh S, Mora-Medina R, Ayala-Soldado N · 2026 · Animals : an open access journal from MDPI
Bivalves are widely used in aquatic monitoring, but the potential of their shells to provide comparative metal signatures remains insufficiently explored in the Caspian Sea. This study quantified major and trace elements in empty shells of…
Alvina, Jaffar H, Onwuzo CN et al. · 2026 · Digestive diseases and sciences
Background Biliary adverse events (AEs) have been reported with glucagon-like peptide-1 receptor agonists (GLP-1RAs), but within-class differences remain unclear. Methods We conducted a disproportionality analysis of FAERS comparing…
Ding J, Li X · 2026 · Biology
Soil depth and habitat degradation can reshape fungal communities in salt-affected wetlands, but their effects on fungal ecological processes remain insufficiently understood. This study examined soil fungi in the Halahai Provincial Nature…
Zaini AZ, Loganathan T, Danaee M et al. · 2026 · Journal of racial and ethnic health disparities
Background Equitable healthcare access is a key aspect of health equity, yet migrants face substantial barriers. In Malaysia, migrant workers encounter structural and socio-economic barriers to healthcare. Acculturation and social support…
Nagakura Y, Yamaki F, Saimaru H et al. · 2026 · Currents in pharmacy teaching & learning
Introduction In Japanese pharmacy education, success on the National Pharmacist Examination is a key objective. This study evaluated learning gain across face-to-face, mixed-attendance, and live online participation patterns in a…
Long CY, Chang CY, Sung IC et al. · 2026 · Frontiers in bioengineering and biotechnology
Background Interstitial cystitis (IC) is a disease comprised of multiple symptoms, included persistent bladder pain syndrome (BPS), frequent urination, and urgency without getting infection or other identifiable causes. Methods In our…
Li L, Wang C, Ji Y et al. · 2026 · Behavioral sciences (Basel, Switzerland)
Previous research suggests receiving a concurrent auditory version of text during reading, i.e., reading-while-listening, improves eye-movement behavior in less skilled readers, while disrupting skilled reading. We extended this approach…
Seiser M, Deininger C, Fierlbeck J et al. · 2026 · European journal of trauma and emergency surgery : official publication of the European Trauma Society
Purpose External fixators are essential for the surgical management of long-bone fractures, particularly in resource-limited settings where access to commercial systems is often restricted by cost and logistics. This study aimed to develop…