A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
20240 results in Negative / Null Result Report · page 323 of 675
Yang J, Zhu D, Liu R et al. · 2026 · Bioresource technology
Partial nitritation (PN) underpins two-stage anaerobic ammonium oxidation-based nitrogen removal, but biomass management in sidestream PN reactors remains largely empirical. This study tested three PN sequencing batch reactors maintained…
Ashraf A, Shamel M, Massieh C et al. · 2026 · BMC oral health
Background Energy drinks are acidic beverages with recognized erosive potential, but their effect on enamel characteristics relevant to orthodontic bonding remains incompletely described. This in vitro study evaluated the effect of…
Mata M, Harmand MG, Prada-Arrondo PC et al. · 2026 · Preprint
Objective Older adults undergoing cardiac surgery may be vulnerable to postoperative cognitive decline. However, no studies have examined postoperative cognitive outcomes in older patients with cardiovascular disease (CVD) according to…
Ganji SK, Talari K, Maloth RK et al. · 2026 · Rapid communications in mass spectrometry : RCM
Rationale Nitrite anion is among the highly reactive anions and converts the secondary amines to their corresponding carcinogenic N-nitroso metabolites in the human body. Nitrite ion is highly abundant in natural waters and enters the body…
Niu J, Huang W, Zou J · 2026 · Clinical neurology and neurosurgery
Purpose To compare rupture-related signals captured by automatically extracted computed tomography angiography (CTA) morphologic features and threshold-based computed tomography perfusion (CTP) metrics in large unruptured intracranial…
Sezen E, Kurtulmus H · 2026 · Preprint
Abstract Background To compare the time-dependent retentive-force behavior and wear-related surface alterations of two unsplinted overdenture attachment systems, a ball attachment system and a TRI Raptor Smart Box system, after…
Xie B, Rui Y · 2026 · Plants (Basel, Switzerland)
Nanotechnology has attracted increasing attention in agricultural and environmental research, but the biological effects and potential risks of nanoparticles based on non-essential elements remain insufficiently understood. This study…
Potdar A, Kumari A · 2026 · Preprint
Abstract Solar radio bursts in the metric and decametric ranges are direct signatures of accelerated electrons in the solar atmosphere. It is almost always the case that these bursts are associated with solar flares. In the present study,…
Destro JM, Reis BO, Chrisostomo DA et al. · 2026 · Journal of functional biomaterials
This study aimed to evaluate the effects of experimental bioactive glass solutions on dentinal fluid flow and hydraulic conductance in vitro. Dentin blocks of 50 bovine incisors were divided into 5 groups according to the desensitizing…
Xu Z, Su S, Xu Z et al. · 2026 · Frontiers in psychology
The Drive for Muscularity Attitudes Questionnaire (DMAQ) is a brief tool for assessing muscularity-related attitudes. This study translated the DMAQ into Chinese and evaluated its reliability and validity separately in males and females. A…
Koyuncu Z, Evcil FY, Kilimci ÖS et al. · 2026 · BMC psychiatry
Objective This study investigated whether current comorbid psychiatric symptoms were involved in statistical indirect associations between childhood attention-deficit/hyperactivity disorder (ADHD) symptoms (CAS) and functional impairment…
Hirano K, Seki T, Watanabe A et al. · 2026 · Preprint
Background Initiation of emergency dialysis, often requiring temporary catheter owing to unprepared definitive vascular access, is associated with infectious and vascular complications and suggests advanced chronic kidney disease (CKD)…
Gessler KB, Rescaroli J, Pires SM et al. · 2026 · Neurotoxicity research
Atorvastatin is a widely prescribed statin used for its cholesterol-lowering effects; however, it also exerts known pleiotropic effects, including antioxidant and anti-inflammatory properties. Atorvastatin´s impact on mitochondrial…
Pan Y, Sun Y, Shi C et al. · 2026 · Preprint
Abstract Genetic testing guides personalized management of differentiated thyroid carcinoma (DTC). However, tumor heterogeneity, including spatial and temporal heterogeneity, has created an unresolved clinical problem. It remains unclear…
Tuo Y, Yang S, Dai X et al. · 2026 · Journal of ethnopharmacology
Ethnopharmacological relevance Syringa oblata Lindl. emits a variety of biogenic volatile organic compounds (BVOCs) during full bloom, which forms the key chemical basis for its characteristic floral scent. Species of the genus Syringa…
Partoazar A, Shahabi S, Afrasiabi S · 2026 · BMC oral health
Background Biofilms contribute to the dental calculus formation, which in turn deteriorates oral and systemic health. The use of antimicrobial photodynamic therapy (PDT) may be limited by problems with photosensitizer penetration. In…
Lipa AJ, Janata-Schwatczek K, Sterz M et al. · 2026 · Seminars in thrombosis and hemostasis
Pulmonary embolism (PE) in octogenarians (i.e., patients > 80 years) is associated with substantial morbidity and mortality, yet this population remains underrepresented in major studies. We compared the predictive performance of the…
Chen W, Ge X, Hu C et al. · 2026 · Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Prospective studies are necessary to determine the association between circulating proteins and colorectal cancer (CRC) risk, offering non-invasive biomarkers for early CRC risk prediction and interventions. The Olink Explore-3072 platform…
Umer H, Mumtaz T, Weiskirchen R et al. · 2026 · Chronobiology international
Disruption of circadian rhythm is common in rotating shift workers, individuals with jet lag, and people with irregular sleep schedules and contributes to metabolic diseases including obesity, type 2 diabetes, metabolic…
Liu Y, Tao G, Zhao Y et al. · 2026 · Frontiers in medicine
Objective To characterize choroidal structural and perfusion changes in children with emmetropia, low myopia, and moderate myopia using enhanced depth imaging optical coherence tomography (EDI-OCT) and optical coherence tomography…
Kurogochi K, Stern JA, DeFrancesco TC et al. · 2026 · Journal of the American Veterinary Medical Association
Objective The T-wave peak-end (TpTe) interval and its ratio to the QT interval (TpTe:QT) are ECG markers of myocardial repolarization dispersion. We hypothesized that these markers are associated with echocardiographic indices reflecting…
Eydou Z, Garber S, Sikkema M · 2026 · Cureus
Fusobacterium necrophorum is a recognized cause of brain abscesses and has been classically associated with Lemierre syndrome. We report a case of a 17-year-old male patient who presented with seizures, fever, and altered mental status…
Szeto CYY, Kwan HS · 2026 · Preprint
Dietary and lifestyle microbiome interventions often produce mild but heterogeneous remodeling rather than uniform community shifts. In this setting, scalar diversity or group-level summaries can appear weak or inconclusive even when…
Boualia B, Sandeli A, Boulebd H et al. · 2026 · ACS omega
In this research, we present the successful synthesis of benzimidazolium salts ( 2a - e ) and their corresponding selenium-NHC adducts ( 3a - e ), achieved with satisfactory yields ranging from 75% to 88%, and characterized using…
Qaid MM, Al-Garadi MA, Al-Abdullatif AA et al. · 2026 · Poultry science
Coccidiosis remains a major constraint in poultry production; therefore, this study evaluated the anticoccidial efficacy of a phytogenic blend of cinnamon bark and Rumex nervosus leaf in Eimeria tenella-challenged broilers. Birds were…
Hayashi E, Kano H, Nakamura K et al. · 2026 · Respirology case reports
Small-cell lung cancer (SCLC) has a poor prognosis, and the efficacy of tarlatamab for untreated brain metastases remains unclear. We report a case demonstrating a discrepant response between extracranial and intracranial lesions after…
Wei X, Xue M, Fan B et al. · 2026 · BMC pulmonary medicine
Background Long-term changes in lung function in children with symptom control asthma are rare. To assess the trajectory of pulmonary function in children and analyze the influence factors. Methods The effects of gender, age, Body Mass…
Eltahir M, Young K, Younes S et al. · 2026 · American journal of clinical pathology
Objectives Determination of B-cell clonality in formalin-fixed, paraffin-embedded tissues is challenging, especially in cases where tumor B cells are sparse. Flow cytometry is of limited utility in Hodgkin lymphomas, at least in part due…
Hauck F, Herber V, Moecke S et al. · 2026 · International journal of oral implantology (Berlin, Germany)
Purpose The aim of this pilot preclinical study was to investigate the performance of a novel double-lead thread, conical bone-level ceramic implant manufactured by injection moulding (test group) in comparison to a well-established…
Uğurlu İ · 2026 · Journal of clinical laboratory analysis
Background Apelin-13 and Galectin-3 (Gal-3) are bioactive mediators linked to inflammation and cardiometabolic pathways. Their clinical utility in COVID-19 alongside routine laboratory tests remains unclear. Methods In this case-control…