Negative / Null Result ReportOpen accessMedicine
Bertsias A, Flouri I, Emmanouilidou E et al. · 2026 · Arthritis research & therapy
Background Difficult to manage (D2M) axial spondyloarthritis (axSpA) is an evolving clinical concept. We aimed to assess the prevalence, predictors and long-term outcomes of D2M axSpA. Methods Prospective single center cohort study of…
View details →DOI: 10.1186/s13075-026-03732-x Negative / Null Result ReportOpen accessMedicine
Bošnjak K, Vengust R · 2025 · Journal of clinical medicine
Background : We aimed to analyze radiographic sagittal balance parameters in patients who underwent a TLIF procedure for single-level degenerative spondylolisthesis with a mean follow-up of 8.6 years and to determine whether lumbar…
View details →DOI: 10.3390/jcm14155457 Negative / Null Result Report
Ribic A, McCoy E, Pendala V et al. · 2024 · Preprint
Abstract Preterm birth is a leading risk factor for atypicalities in cognitive and sensory processing, but it is unclear how prematurity impacts circuits that support these functions. To address this, we trained adult mice born a day early…
View details →DOI: 10.21203/rs.3.rs-5529783/v1 Negative / Null Result ReportOpen accessMedicine
Ikegishi Y, Abe R, Maehata A et al. · 2026 · Internal medicine (Tokyo, Japan)
Copper deficiency is a rare but critical cause of anemia and neurological impairment. We herein report a hemodialysis patient who developed acute-onset copper deficiency after spinal surgery with zinc supplementation, despite no…
View details →DOI: 10.2169/internalmedicine.5960-25 Negative / Null Result ReportOpen accessMedicine
Umer A, Nafis S, Karimi M · 2026 · Cureus
Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare inherited bone marrow failure disorder characterized by severe thrombocytopenia due to absent or markedly decreased megakaryocytes. It typically presents in infancy and may…
View details →DOI: 10.7759/cureus.102147 Negative / Null Result ReportMedicine
Pisljar Z, Markelc B, Brezar SK et al. · 2025 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Radiotherapy is a standard therapy for oral squamous cell carcinoma (OSCC) with immunomodulatory potential. Due to high lymphocyte radiosensitivity, partial tumor-volume irradiation (pIR), targeting only part of the tumor, is being…
View details →DOI: 10.1016/j.biopha.2025.118107 Negative / Null Result ReportMedicine
Paul N, Weiss B · 2025 · Die Anaesthesiologie
With a decrease in mortality of critically ill patients in recent years, intensive care medicine research has shifted its focus on functional impairments of intensive care units (ICU) survivors. ICU survivorship is characterized by…
View details →DOI: 10.1007/s00101-024-01483-5 Negative / Null Result ReportOpen accessMedicine
Aguila L, Castillo R, Pérez-García F et al. · 2026 · Animals : an open access journal from MDPI
Haploid embryos constitute a valuable model for genetic and epigenetic studies; however, their developmental competence is reduced compared with diploid counterparts. This study evaluated whether supplementation of the culture medium with…
View details →DOI: 10.3390/ani16101517 Negative / Null Result ReportMedicine
Vicenti C, Cercone M, Nieman G et al. · 2025 · Veterinary Anaesthesia and Analgesia
To compare early versus late time-controlled adaptive ventilation (TCAV) for setting airway pressure release ventilation (APRV) on arterial oxygenation in dorsally recumbent anesthetized horses. A crossover, nonrandomized, experimental…
Negative / Null Result ReportOpen accessMedicine
Kaplan A, Malik S, Persaud NA et al. · 2025 · Cureus
Fragile X syndrome (FXS) is classified as a genetic disorder located in the fragile X messenger ribonucleoprotein-1 (FMR1) gene on the X chromosome. FXS is considered the most prevalent single-gene cause of intellectual disability and…
View details →DOI: 10.7759/cureus.88159 Negative / Null Result ReportMedicine
Calvani R, Giampaoli O, Marini F et al. · 2024 · Clinical nutrition (Edinburgh, Scotland)
Background & aims Long-term effects of coronavirus disease 2019 (long COVID) develop in a substantial number of people following an acute COVID-19 episode. Red beetroot juice may have positive effects on multiple pathways involved in long…
View details →DOI: 10.1016/j.clnu.2024.11.023 Negative / Null Result ReportOpen accessMedicine
Tardif A, Boulay ME, Côté A et al. · 2026 · Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology
BACKGROUND: Tezepelumab is the most recent human monoclonal antibody in the therapeutic arsenal of patients with severe uncontrolled asthma. It neutralizes thymic stromal lymphopoietin (TSLP). Phase 2 and phase 3 studies showed a…
View details →DOI: 10.1186/s13223-026-01037-x Negative / Null Result ReportOpen accessMedicine
Fu Y, Zhang Y, Deng Q et al. · 2025 · BMC psychiatry
Background Post-stroke depression (PSD) constitutes an important complication of stroke, affecting approximately one-third of stroke patients. PSD decreases rehabilitation motivation, delays function recovery, and increases the family and…
View details →DOI: 10.1186/s12888-025-06673-y Negative / Null Result ReportMedicine
Kateh Shamshiri M, Vakili-Ghartavol R, Aiyelabegan HT et al. · 2025 · Cytokine
While liposomes enhance the safety and pharmacokinetic profile of free drugs, they have not significantly improved therapeutic efficacy. To overcome this challenge, targeted depletion of tumor-associated macrophages (TAMs) shows…
View details →DOI: 10.1016/j.cyto.2025.156860 Negative / Null Result ReportMedicine
Lamboley Q, Fourcade Y · 2024 · Journal of biogeography
AIM: The continuous development of statistical tools applied to ecology has contributed to great advances for modelling species' niches and distributions from opportunistic observations. However, as these observations are subject to biases…
Negative / Null Result ReportMedicine
Alghizzi TM, Alshahrani TM · 2024 · Heliyon
Despite considerable evidence that supports the use of grading rubrics (GRs) as tools for written corrective feedback, there is a paucity of research that investigates which of the different types of GRs best develops learners'…
Negative / Null Result Report
Siegrist H, Spieler A, Peters AS et al. · 2024 · Preprint
There is currently no clinically valid biomarker for predicting the growth and prognosis of abdominal aortic aneurysms (AAA). The most promising candidates with highest diagnostic values are plasma D-dimers and markers of activated…
View details →DOI: 10.20944/preprints202410.2260.v1 Negative / Null Result Report
Lefebvre C, Tiffay A, Breemeersch C et al. · 2024 · Preprint
Rationale Obesity is often associated with sex-dependent metabolic complications, in which altered intestinal barrier function and gut microbiota contribute. Glutamine (Gln) supplementation previously showed beneficial effects on gut…
View details →DOI: 10.1101/2024.11.21.624683 Negative / Null Result ReportOpen accessMedicine
Bousamaki J, Maciag G, Petersen AG et al. · 2026 · Basic & clinical pharmacology & toxicology
Nintedanib, a multitargeted tyrosine kinase inhibitor, is approved for idiopathic pulmonary fibrosis (IPF) for its ability to slow lung function decline. This study systematically evaluated the effects of nintedanib across three…
View details →DOI: 10.1111/bcpt.70220 Negative / Null Result ReportMedicine
Güngör HS, Łabuz G, Yildirim TM et al. · 2024 · Journal of refractive surgery (Thorofare, N.J. : 1995)
Purpose To investigate how varying levels of longitudinal chromatic aberration (LCA) affect visual quality in patients with trifocal intraocular lenses (IOLs). Methods Twenty-nine patients implanted with trifocal IOLs were assessed for…
View details →DOI: 10.3928/1081597x-20240731-03 Negative / Null Result ReportOpen accessMedicine
Hui Q, Xiang T, Qinglan X et al. · 2026 · Food science & nutrition
The link between Vitamin D (Vit D) deficiency and sudden sensorineural hearing loss (SSNHL), especially regarding recurrence and age-related disparities, remains unclear. Recurrence and age-specific risks of SSNHL are under addressed,…
View details →DOI: 10.1002/fsn3.71383 Negative / Null Result ReportOpen accessMedicine
Tanabe S, Shi Y · 2024 · The American journal of case reports
BACKGROUND Retained products of conception (RPOC) is a rare complication following second-trimester delivery or pregnancy termination, often leading to significant hemorrhage. Diagnosed via ultrasound or CT, RPOC requires surgical…
View details →DOI: 10.12659/ajcr.945672 Negative / Null Result ReportMedicine
Hyun J, Cerino ES, Katz MJ et al. · 2025 · The journals of gerontology. Series B, Psychological sciences and social sciences
Objectives Investigating social determinants of health and related outcomes may help identify effective and sustainable intervention targets. This study examined whether contextual-level social capital (bonding and bridging capital) and…
View details →DOI: 10.1093/geronb/gbaf157 Negative / Null Result ReportOpen accessMedicine
Kumekawa T, Akaihata H, Natsuya H et al. · 2024 · IJU case reports
Introduction Human T-cell lymphotropic virus type 1 infection can cause HTLV-1-associated myelopathy/tropical spastic paraparesis, characterized by spastic paralysis of both lower limbs. More than 90% of HAM/TSP patients show lower urinary…
View details →DOI: 10.1002/iju5.12773 Negative / Null Result Report
Su X, Zhang L, Sun Y et al. · 2024 · Preprint
Abstract Background The diverse types and processing methods of grains intricately influence the sites and digestibility of starch digestion, thereby impacting energy utilization. This study aimed to explore the impact of grain variety and…
View details →DOI: 10.21203/rs.3.rs-4958601/v1 Negative / Null Result ReportOpen accessMedicine
Nikolaeva A, Vandeputte M · 2025 · Endocrinology, diabetes & metabolism case reports
Summary Semaglutide, a GLP-1 receptor agonist (RA), is approved for the treatment of type 2 diabetes and obesity. However, its increasing off-label use, particularly for cosmetic weight loss, raises concerns considering its potential…
View details →DOI: 10.1530/edm-25-0081 Negative / Null Result ReportMedicine
El Idrissi Y, El Moudden H, Belhoussaine O et al. · 2025 · Chemistry & biodiversity
This study investigates for the first time the effects of UV light exposure on the chemical composition of artisanal and cold-pressed culinary and cosmetic argan oils, as well as their quality and biological activities. We ascertained the…
View details →DOI: 10.1002/cbdv.202401262 Negative / Null Result ReportMedicine
Jhaj J, Woolner B, Rankin S et al. · 2025 · Shoulder & elbow
This study evaluated the outcome and recurrence rates after hydrodilatation (HD) in patients with frozen shoulder (FS), comparing the effects of injecting 25 mL or more of fluid versus lower volumes. A total of 132 shoulders (130 patients)…
View details →DOI: 10.1177/17585732241307860 Negative / Null Result ReportMedicine
Banerjee S, Berry Y, Fisher E et al. · 2025 · Neuroscience letters
Genetic leukoencephalopathy (gLE) is a white matter disorder affecting the central nervous system, causing hypomyelination, developmental delays, motor deterioration, and cognitive, visual, and hearing impairments. Its clinical variability…
View details →DOI: 10.1016/j.neulet.2025.138280 Negative / Null Result ReportMedicine
Alsheekh A, Kibrik P, Marks N et al. · 2025 · Vascular
BackgroundThe minimally invasive procedures of venous ablation and iliac vein stenting are evolving treatment options for venous insufficiency. Yet, there are no studies directly comparing the outcome of these procedures. We performed a…
View details →DOI: 10.1177/17085381241273222 